EP1011654A4 - METHODS FOR MODULATING CELL ACTIVITY - Google Patents

METHODS FOR MODULATING CELL ACTIVITY

Info

Publication number
EP1011654A4
EP1011654A4 EP98941157A EP98941157A EP1011654A4 EP 1011654 A4 EP1011654 A4 EP 1011654A4 EP 98941157 A EP98941157 A EP 98941157A EP 98941157 A EP98941157 A EP 98941157A EP 1011654 A4 EP1011654 A4 EP 1011654A4
Authority
EP
European Patent Office
Prior art keywords
cellular activity
modulating cellular
modulating
activity
cellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98941157A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1011654A1 (en
Inventor
Mathew Vadas
Jennifer Gamble
Pu Xia
Philip Barter
Kerry-Anne Rye
Brian Wattenberg
Stuart Pitson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Research and Development LLC
Original Assignee
Johnson and Johnson Pharmaceutical Research and Development LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson Pharmaceutical Research and Development LLC filed Critical Johnson and Johnson Pharmaceutical Research and Development LLC
Publication of EP1011654A1 publication Critical patent/EP1011654A1/en
Publication of EP1011654A4 publication Critical patent/EP1011654A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Food Science & Technology (AREA)
  • Vascular Medicine (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
EP98941157A 1997-09-08 1998-09-08 METHODS FOR MODULATING CELL ACTIVITY Withdrawn EP1011654A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPO900297 1997-09-08
AUPO9002A AUPO900297A0 (en) 1997-09-08 1997-09-08 A method of modulating cellular activity
PCT/AU1998/000730 WO1999012533A1 (en) 1997-09-08 1998-09-08 A method of modulating cellular activity

Publications (2)

Publication Number Publication Date
EP1011654A1 EP1011654A1 (en) 2000-06-28
EP1011654A4 true EP1011654A4 (en) 2004-09-15

Family

ID=3803288

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98941157A Withdrawn EP1011654A4 (en) 1997-09-08 1998-09-08 METHODS FOR MODULATING CELL ACTIVITY

Country Status (5)

Country Link
EP (1) EP1011654A4 (https=)
JP (1) JP4570246B2 (https=)
AU (2) AUPO900297A0 (https=)
CA (1) CA2302838C (https=)
WO (1) WO1999012533A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100798375B1 (ko) * 1999-05-13 2008-01-28 존슨 앤드 존슨 파머슈티컬 리서치 앤드 디벨로프먼트 엘엘씨 스핀고신 키나제 효소
AUPQ744700A0 (en) * 2000-05-11 2000-06-01 Medvet Science Pty. Ltd. A method of treatment and agents useful for same
EP1195604A1 (en) * 2000-09-29 2002-04-10 Warner-Lambert Company Methods and compositions for screening modulators of lipid kinases
US6610534B2 (en) * 2000-10-05 2003-08-26 Novartis Ag Induction of blood vessel formation through administration of polynucleotides encoding sphingosine kinases
US20050100547A1 (en) * 2001-06-07 2005-05-12 Pu Xia Etal Sphingosine kinase interacts with traf2 and modulates tumor necrosis factor-induced cellular activity
JP2005526809A (ja) * 2002-03-28 2005-09-08 メドベット サイエンス ピーティーワイ． リミティッド 細胞活性を調節する方法
MXPA05003974A (es) * 2002-10-14 2005-08-03 Medvet Science Pty Ltd Un metodo de modulacion de la actividad celular epitelial mediante la modulacion de los niveles funcionales de la esfingosina cinasa.
EP1481680A1 (en) * 2003-05-30 2004-12-01 Aventis Pharma Deutschland GmbH Use of S1P
EP1765384A4 (en) * 2004-06-15 2009-07-08 Medvet Science Pty Ltd METHOD FOR MODULATING CELLULAR ACTIVITY WITH SPHINGOSINE KINASE AND AGENTS THEREFOR, AND SPHINGOSINE KINASE VARIANTS
AU2005253643B2 (en) * 2004-06-15 2011-12-01 Medvet Science Pty. Ltd. Methods of modulating cellular activity involving sphingosine kinase and agents for same, and sphingosine kinase variants
EP1845971A4 (en) * 2005-01-21 2009-12-30 Medvet Science Pty Ltd METHOD FOR THE TREATMENT OF CELL DAMAGE
JP2013533286A (ja) 2010-07-30 2013-08-22 セントルイス ユニバーシティ 疼痛を治療する方法
WO2017015334A1 (en) 2015-07-21 2017-01-26 Saint Louis University Compositions and methods for diagnosing and treating endometriosis-related infertility

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766111A (en) * 1985-10-31 1988-08-23 Trustees Of Boston University Lipids with plasmin inhibitory properties
ATE133423T1 (de) * 1987-05-20 1996-02-15 Rogosin Inst Rekonstituierte hdl-teilchen und ihre verwendung
US5190876A (en) * 1988-12-27 1993-03-02 Emory University Method of modifying cellular differentiation and function and compositions therefor
CA2007507C (en) * 1989-02-03 1998-05-19 Yasuyuki Igarashi Sphingosine and n-methyl-sphingosine as inhibitor of cell growth
US5466716A (en) * 1990-12-31 1995-11-14 The Biomembrane Institute Liposomal trimethylsphingosine
CA2165982A1 (en) * 1993-07-23 1995-02-02 Fuqiang Ruan N,n,n-trimethylsphingosine derivatives
AU717243B2 (en) * 1994-12-29 2000-03-23 Regents Of The University Of California, The Compounds for inhibition of ceramide-mediated signal transduction
US5677189A (en) * 1995-06-29 1997-10-14 Oncomembrane, Inc. Method for quantifying sphingosine and for diagnosing platelet activation
JPH09176083A (ja) * 1995-12-28 1997-07-08 Sankyo Co Ltd 新規化合物ｆ−１２５０９ａ

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AFTAB D T ET AL: "A semiautomated 96-well plate assay for protein kinase C", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC, NEW YORK, vol. 187, no. 1, 15 May 1990 (1990-05-15), pages 84 - 88, XP024819783, ISSN: 0003-2697, [retrieved on 19900515], DOI: 10.1016/0003-2697(90)90420-E *
No further relevant documents disclosed *
See also references of WO9912533A1 *

Also Published As

Publication number Publication date
EP1011654A1 (en) 2000-06-28
AU8965898A (en) 1999-03-29
CA2302838A1 (en) 1999-03-18
AU757358B2 (en) 2003-02-20
JP4570246B2 (ja) 2010-10-27
CA2302838C (en) 2010-03-16
JP2001515857A (ja) 2001-09-25
AUPO900297A0 (en) 1997-10-02
WO1999012533A1 (en) 1999-03-18

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Effective date: 20150106