EP1007072A4 - Recepteurs du facteur neurotrophique derive de lignes de cellules gliales - Google Patents
Recepteurs du facteur neurotrophique derive de lignes de cellules glialesInfo
- Publication number
- EP1007072A4 EP1007072A4 EP98920199A EP98920199A EP1007072A4 EP 1007072 A4 EP1007072 A4 EP 1007072A4 EP 98920199 A EP98920199 A EP 98920199A EP 98920199 A EP98920199 A EP 98920199A EP 1007072 A4 EP1007072 A4 EP 1007072A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cell line
- neurotrophic factor
- derived neurotrophic
- factor receptors
- glial cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000004216 Glial cell line-derived neurotrophic factor receptors Human genes 0.000 title 1
- 108090000722 Glial cell line-derived neurotrophic factor receptors Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/861,990 US6696259B1 (en) | 1995-11-13 | 1997-05-22 | Assays using glial cell line-derived neurotrophic factor receptors |
US861990 | 1997-05-22 | ||
PCT/US1998/009056 WO1998052591A1 (fr) | 1997-05-22 | 1998-05-04 | Recepteurs du facteur neurotrophique derive de lignes de cellules gliales |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1007072A1 EP1007072A1 (fr) | 2000-06-14 |
EP1007072A4 true EP1007072A4 (fr) | 2002-06-26 |
Family
ID=25337323
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98920199A Withdrawn EP1007072A4 (fr) | 1997-05-22 | 1998-05-04 | Recepteurs du facteur neurotrophique derive de lignes de cellules gliales |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1007072A4 (fr) |
JP (1) | JP2001527418A (fr) |
KR (1) | KR20010012826A (fr) |
AU (1) | AU741208B2 (fr) |
CA (1) | CA2290426A1 (fr) |
NO (1) | NO995691L (fr) |
NZ (1) | NZ501199A (fr) |
WO (1) | WO1998052591A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6677135B1 (en) | 1996-05-08 | 2004-01-13 | Biogen, Inc. | Ret ligand (RetL) for stimulating neutral and renal growth |
DE19816186A1 (de) * | 1998-04-14 | 1999-10-21 | Univ Muenchen L Maximilians | GDNF-kodierende DNA, Teile davon und GDNF-Varianten |
FI20030130A0 (fi) | 2003-01-29 | 2003-01-29 | Licentia Oy | Seulontamenetelmä |
IL261666B1 (en) | 2016-03-31 | 2024-05-01 | Ngm Biopharmaceuticals Inc | Related proteins and methods of using them |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997044356A2 (fr) * | 1996-05-08 | 1997-11-27 | Biogen, Inc. | Test diagnostique de detection de la schizophrenie faisant appel a de la miacine |
WO1998036072A1 (fr) * | 1997-02-18 | 1998-08-20 | Genentech, Inc. | Recepteur de la neurturine |
WO1998046622A1 (fr) * | 1997-04-17 | 1998-10-22 | Washington University | RECEPTEURS DES FACTEURS NEUROTROPHIQUES ASSOCIES AU TGF-$g(b) |
WO1998053069A2 (fr) * | 1997-05-20 | 1998-11-26 | Human Genome Sciences, Inc. | Recepteurs du gdnf |
WO1998054213A2 (fr) * | 1997-05-30 | 1998-12-03 | Amgen Inc. | Recepteurs du facteur neurotrope |
-
1998
- 1998-05-04 KR KR19997010790A patent/KR20010012826A/ko not_active Application Discontinuation
- 1998-05-04 JP JP55040098A patent/JP2001527418A/ja not_active Ceased
- 1998-05-04 EP EP98920199A patent/EP1007072A4/fr not_active Withdrawn
- 1998-05-04 WO PCT/US1998/009056 patent/WO1998052591A1/fr not_active Application Discontinuation
- 1998-05-04 AU AU72825/98A patent/AU741208B2/en not_active Ceased
- 1998-05-04 NZ NZ501199A patent/NZ501199A/en unknown
- 1998-05-04 CA CA002290426A patent/CA2290426A1/fr not_active Abandoned
-
1999
- 1999-11-19 NO NO995691A patent/NO995691L/no not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997044356A2 (fr) * | 1996-05-08 | 1997-11-27 | Biogen, Inc. | Test diagnostique de detection de la schizophrenie faisant appel a de la miacine |
WO1998036072A1 (fr) * | 1997-02-18 | 1998-08-20 | Genentech, Inc. | Recepteur de la neurturine |
WO1998046622A1 (fr) * | 1997-04-17 | 1998-10-22 | Washington University | RECEPTEURS DES FACTEURS NEUROTROPHIQUES ASSOCIES AU TGF-$g(b) |
WO1998053069A2 (fr) * | 1997-05-20 | 1998-11-26 | Human Genome Sciences, Inc. | Recepteurs du gdnf |
WO1998054213A2 (fr) * | 1997-05-30 | 1998-12-03 | Amgen Inc. | Recepteurs du facteur neurotrope |
Non-Patent Citations (9)
Title |
---|
BALOH R H ET AL: "TRNR2, A NOVEL RECEPTOR THAT MEDIATES NEURTURIN AND GDNF SIGNALING THROUGH RET", NEURON, CAMBRIDGE, MA, US, vol. 18, 23 May 1997 (1997-05-23), pages 793 - 802, XP002065821 * |
DATABASE EMBL 4 July 1997 (1997-07-04), M. TRUPP ET AL: "rattus novegicus glial cell line-derived neurotrophic factor receptor-beta", XP002196288 * |
JING S ET AL: "GDNF-INDUCED ACTIVATION OF THE RET PROTEIN TYROSINE KINASE IS MEDIATED BY GDNFR-ALPHA, A NOVEL RECEPTOR FOR GDNF", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 85, 28 June 1996 (1996-06-28), pages 1113 - 1124, XP002036435, ISSN: 0092-8674 * |
JING S ET AL: "GFRALPHA-2 AND GFRALPHA-3 ARE TWO NEW RECEPTORS FOR LIGANDS OF THE GDNF FAMILY", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 272, no. 52, 26 December 1997 (1997-12-26), pages 33111 - 33117, XP002065824, ISSN: 0021-9258 * |
M. TRUPP ET AL: "Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase", MOL.CELL. NEUROSCI., vol. 11, no. 1-2, 1998, pages 47 - 63 * |
SANICOLA M ET AL: "GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR-DEPENDENT RET ACTIVATION CAN BE MEDIATED BY TWO DIFFERENT CELL-SURFACE ACCESSORY PROTEINS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 94, no. 12, 1 June 1997 (1997-06-01), pages 6238 - 6243, XP002059966, ISSN: 0027-8424 * |
See also references of WO9852591A1 * |
SUVANTO PETRO ET AL: "Cloning, mRNA distribution and chromosomal localisation of the gene for glial cell line-derived neurotrophic factor receptor beta, a homologue to GDNFR-alpha.", HUMAN MOLECULAR GENETICS, vol. 6, no. 8, August 1997 (1997-08-01), pages 1267 - 1273, XP002196287, ISSN: 0964-6906 * |
TREANO J J S ET AL: "CHARACTERIZATION OF A MULTICOMPONENT RECEPTOR FOR GDNF", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 382, no. 6586, 4 July 1996 (1996-07-04), pages 80 - 83, XP002047616, ISSN: 0028-0836 * |
Also Published As
Publication number | Publication date |
---|---|
JP2001527418A (ja) | 2001-12-25 |
AU741208B2 (en) | 2001-11-22 |
WO1998052591A1 (fr) | 1998-11-26 |
CA2290426A1 (fr) | 1998-11-26 |
NO995691D0 (no) | 1999-11-19 |
EP1007072A1 (fr) | 2000-06-14 |
AU7282598A (en) | 1998-12-11 |
NO995691L (no) | 2000-01-19 |
NZ501199A (en) | 2001-12-21 |
KR20010012826A (ko) | 2001-02-26 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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Effective date: 19991209 |
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A4 | Supplementary search report drawn up and despatched |
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Effective date: 20040820 |
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Effective date: 20040820 |
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Ref country code: HK Ref legal event code: WD Ref document number: 1028356 Country of ref document: HK |
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Effective date: 20061107 |