EP1001826A1 - Implant syringe - Google Patents

Implant syringe

Info

Publication number
EP1001826A1
EP1001826A1 EP98945024A EP98945024A EP1001826A1 EP 1001826 A1 EP1001826 A1 EP 1001826A1 EP 98945024 A EP98945024 A EP 98945024A EP 98945024 A EP98945024 A EP 98945024A EP 1001826 A1 EP1001826 A1 EP 1001826A1
Authority
EP
European Patent Office
Prior art keywords
needle
implant
preparation
piston
syringe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98945024A
Other languages
German (de)
French (fr)
Inventor
Roland Kneer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gaplast GmbH
Original Assignee
Gaplast GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gaplast GmbH filed Critical Gaplast GmbH
Publication of EP1001826A1 publication Critical patent/EP1001826A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments

Definitions

  • the invention relates to an implant syringe, from the syringe needle of which an elongated, strand-like preparation with a long-term active ingredient is preferably dispensed by means of a piston.
  • a long-term preparation is usually placed in the abdominal wall of a patient, into which a receiving channel for the preparation has previously been inserted using the syringe needle of the implant syringe.
  • the procedure has been such that, after the puncture channel has been formed, the plunger of the implant syringe is advanced into the syringe needle, while at the same time the entire implant syringe with the syringe needle is withdrawn from the puncture channel, the preparation slowly emerging from the syringe needle and finally leaving it .
  • the problem here is that the advance of the plunger and the retraction of the syringe needle must be coordinated with one another in such a way that the preparation, which is a hard molded article, is inserted exactly into the puncture channel.
  • the preparation is pushed out of the syringe needle faster than it is withdrawn in the puncture channel, the preparation is pushed violently into the tissue of the abdominal wall, which causes great pain in the patient.
  • the syringe needle is withdrawn faster than the preparation this emerges, the result may be that the strand-shaped tablet is not completely absorbed into the puncture channel.
  • the present invention has for its object to provide an implant syringe in which it is ensured that the preparation is placed exactly in the puncture channel, whereby this process - apart from the formation of the puncture channel - is painless.
  • the implant syringe according to the invention has a spacer which limits the advance of the plunger into the syringe needle in such a way that a distance remains between the outlet opening of the syringe needle and the head end of the plunger in the advanced preparation-dispensing position, which is equal to or somewhat larger than the length of the preparation to be dispensed this is.
  • the syringe needle can be withdrawn by a handle in the direction of the spacer by a distance which is at least as long as the length of the preparation or also greater than this.
  • the plunger is thus advanced in a first step after the syringe has been set or the puncture channel has been formed, up to the stop formed by the spacer, as a result of which the strand-shaped tablet located in the implant syringe is advanced up to the needle tip, whereupon the syringe needle is held immovably by a handle at least until the preparation is exposed.
  • This means reliably ensures that the strand-like preparation is not pushed past the needle tip, ie beyond the end of the puncture channel, ie it is impossible to press the hard tablet strand into the patient's tissue.
  • the preparation Since the preparation is brought into a position by the advance of the plunger, in which it is located at the needle tip and thus at the end of the puncture channel, it is also ensured that the entire length of the specimen is placed in the puncture channel since the preparation is not withdrawn as it emerges from the syringe needle. Instead, the syringe needle is withdrawn from the preparation while the latter is held in position by the plunger.
  • the front end face of the syringe housing surrounding the rear region of the syringe needle should remain in contact with the patient's skin if this end face of the housing serves to limit the length or depth of the puncture channel, as is preferred.
  • the implant syringe according to the invention essentially consists of three main components, namely the spacer, which consists of a base plate, preferably running at a right angle to the longitudinal axis of the syringe, and a guide sleeve attached to it and forming the above-mentioned syringe housing, the front end face of which should limit the puncture depth of the syringe needle, further from the handle, which preferably contains as a handle two tabs lying in a parallel plane to the base plate of the spacer, which protrude from a substantially tubular needle holder of the handle extending in the axial direction of the syringe, the Needle holder contains an axial through hole in which the syringe needle is seated, for example pressed, and the piston, which has the shape of an elongated thin rod and which sits centrally on an end plate on which a sleeve is formed which surrounds the end section of the piston and which
  • the essentially tubular, central extension of the handle, which forms the needle holder has an axial through-hole into which the syringe needle engages.
  • the syringe needle preferably does not extend completely through the through hole of the needle holder, but leaves a rear end section of the through hole free, which here has a restricted free inside diameter which is somewhat smaller than the inside diameter of the syringe needle and, above all, somewhat smaller than the outside diameter of the strand-like preparation is.
  • the inside diameter of the end section of the through-hole can be reduced in that individual projections, which can be, for example, bead-like or nose-shaped, protrude a little inwards, these projections being dimensioned such that a strand-shaped tablet engaging in this end section of the through-hole is prevented from doing so to enter the syringe needle without the action of the plunger and thus accidentally slide out of the implant syringe.
  • the preparation is not kept so tightly in the end portion of the through hole that the advance caused by the piston into the syringe needle is impeded.
  • the grip piece preferably has two tabs which protrude from the tubular needle holder and lie opposite one another, without the invention being restricted to this configuration.
  • the rear end of the substantially tubular needle holder is expediently connected to a likewise essentially tubular element which serves to receive the strand-like preparation, the preparation receiving element having a through hole which is flush with that of the needle holder.
  • the two plastic elements can, for example, be put together or connected to one another with their end faces in any other expedient way. Expediently, they have the same cross-sectional shape with a matching outer diameter, the diameter of the through hole being somewhat larger than the outer diameter of the preparation.
  • the strand-like preparation is expediently inserted into the through bore of the preparation receiving element before the handle piece assembled in the manner described is assembled with the spacer and its guide sleeve.
  • the spacer expediently has a base plate with a central bore in which the rear end of the specimen receiving element is seated in the initial state of the implant syringe, and a guide sleeve which extends in the axial direction and projects at a right angle from the base plate.
  • the guide sleeve preferably has two mutually opposite, through-going slots in the axial direction, that is, it consists of two spaced-apart guide sleeve sections, the tabs of the handle reaching through these slots and projecting outward beyond the guide sleeve so that they are from a user's fingers the implant syringe can be used to pull the syringe needle back to dispense the preparation. This is described in more detail below.
  • a sealing ring for the plunger which, in the initial state of the syringe, engages with its front head end over a small distance in the section of the through hole left free by the specimen.
  • the specimen receiving element is slidably seated in the central hole in the base plate of the spacer. After the preparation has been dispensed, the entire length of the preparation receiving element can have passed through the base plate of the spacer, which will be explained further below.
  • the piston of the implant syringe is expediently fastened to an end plate on which the above-mentioned sleeve is formed, which surrounds a rear piston section.
  • This sleeve has an inner diameter that is larger than the outer diameter of the specimen receiving element and possibly the needle holder.
  • the sleeve surrounding the rear end section of the plunger is expediently surrounded by a removable spacer element, which rests with one end on the base plate of the spacer and with the other end on the end plate of the plunger.
  • This removable spacer element which can be, for example, a sleeve cut open over its entire length, prevents the piston from being inadvertently advanced before the implant syringe is used.
  • the implant syringe according to the invention is handled as follows: First, the puncture channel is formed by inserting the syringe needle into the abdominal wall of a patient, for example, until the front end edge of the two-part guide sleeve of the spacer lies on the patient's skin. The spacer is then removed taken. The piston is then advanced by exerting pressure on the end plate connected to it, the base plate of the spacer being engaged behind. This process ends with the impact of the front end edge of the sleeve surrounding the piston on the base plate of the spacer. The strand-like preparation has been advanced to the outlet opening of the syringe needle.
  • the grip is then pulled back until it stops by reaching behind its protruding tabs.
  • the impact of the rear end edge of the specimen receiving element on the piston end plate can serve as a stop.
  • the invention is not limited to this, but for example the tabs of the handle can strike a stop of the guide sleeve or the base plate of the spacer. When the stop is reached, the preparation is deposited so that the section of the syringe needle that still protrudes beyond the guide sleeve can be pulled out of the puncture channel.
  • the implant syringe according to the invention is preferably a disposable syringe for single use, without the invention being restricted to this.
  • the individual components are preferably made of plastic, with the exception of the syringe needle, which is expediently made of metal.
  • the needle holder can for example consist of a polypropylene or polyethylene, this material being suitable for forming the holding lugs for the preparation.
  • the subsequent specimen receiving element expediently consists of transparent polycarbonate.
  • the invention is of course not limited to these materials.
  • the long-term preparation to be discarded does not necessarily have to have a continuous strand form, although this is usually the case.
  • the implant syringe can also be used to place several tablets arranged one behind the other, for example in spherical form.
  • FIG. 2 shows a section through the implant syringe according to FIG. 1 along the line II-II in FIG. 1;
  • Fig. 3 shows the implant syringe of FIG. 1 in the state in which the preparation is advanced to the needle tip and
  • Fig. 4 shows the implant syringe in the retracted state of the needle.
  • the implant or depot syringe 1 shown in the figures contains a handle, generally designated 2, which consists in one piece of a central tubular or sleeve-shaped needle holder 3 and tabs 4 projecting vertically therefrom.
  • the needle holder 3 is slightly tapered on its section facing forward from the tabs 4.
  • a syringe needle 6 preferably made of metal, which does not extend completely through the through bore 5, but leaves an end section 7 of the through bore 5 free.
  • the end section 7 is the free interior of the through hole 5 by inwardly projecting lugs or beads reduced to such an extent that a strand-like preparation 8 is held there in a slight clamping fit, which prevents the preparation 8 from automatically leaving the implant syringe through the syringe needle 6.
  • the needle holder 3 is connected to a specimen receiving element 9, for example by a plug-in connection, which has the same outer diameter as the adjoining section of the needle holder 3.
  • the through hole 10 of the specimen receiving element 9 is aligned with the through hole 5 of the needle holder 3.
  • a sealing ring 11 made of an elastomer sits in the rear end section of the specimen receiving element 9.
  • the end section of the specimen receiving element 9 is seated in a central through-bore 12 of the base plate 3 of a spacer, generally designated 14.
  • the spacer 14 also contains an integrally formed guide sleeve, which consists of two guide sleeve sections 15, between which two diametrically opposite spaces or slots 16 remain open. These two slots 16 are penetrated by the tabs 4 of the handle piece 2.
  • the handle 2 can thus be moved in the axial direction towards the base plate 13 of the spacer 14, the tabs 4 being guided in the slots 16 of the guide sleeve 15, 15.
  • an elongated rod-shaped piston 17 is seated in the sealing ring 11.
  • the piston 17 is aligned with the preparation 8, which in turn is aligned with the syringe needle 6.
  • the piston 17 is fastened to an end plate 18 which is formed in one piece with a sleeve 18 which surrounds the rear end region of the piston 17 with such a distance that the specimen receiving element 9 enter the space between the sleeve 18 and the piston 17 can, as Fig. 4 shows.
  • the sleeve 18 is surrounded by a slotted spacer 19 over its entire length, which rests on the base plate 13 and the end plate 16 and prevents the piston 17 from being advanced.
  • the spacer sleeve 19 is removed before the piston 17 is advanced.
  • the implant syringe 1 is in the state shown in Fig. 1 e.g. stabbed into the abdominal wall of a patient until the front end edge 20 of the guide sleeve 15 abuts the patient's skin.
  • the piston 17 is - as shown in FIG. 3 - pushed to the left in the figure by means of the end plate 16 until the front end edge 21 of the sleeve 18 bears against the base plate 13.
  • the piston 17 pushes the preparation 8 into the syringe needle 6 and forwards up to the needle tip 22.
  • the handle 2 with the syringe needle 6 is slowly withdrawn in the direction of the base plate 13 of the spacer 14 until the rear end edge 23 of the specimen receiving element 9 bears against the end plate 16.
  • This backward stroke of the handle piece 2 is dimensioned such that the head end of the piston 17 reaches or projects above the needle tip, so that the preparation 8 is completely released.
  • the syringe can now be removed from the patient, the preparation 8 remaining in the puncture channel.
  • the implant syringe 1 is expediently mounted in such a way that, after the handle piece 2 has been plugged together with the specimen receiving element 9, the specimen 8 is inserted into the through bore 10. This arrangement is then assembled with the spacer 14, whereupon the piston 17 is inserted into the end region of the bore 10 and the spacer sleeve 9 is attached.

Abstract

The implant syringe has a spacer which limits the advancement of the piston towards the needle in such a way that a space equivalent to the length of the strand-shaped preparation to be administered remains between the outlet orifice of the needle and the end of the piston head. The needle is connected to a grip end that can be retracted along a distance coinciding with the length of the preparation. An insertion channel is initially made with the implant needle in the body of the patient. Subsequently, the preparation to be administered is pushed forward to the tip of the needle by advancing the piston. The needle is then retracted in such a way that the end of the piston head reaches or surpasses the tip of the needle, upon which the preparation is released. A strand-shaped preparation can be painlessly introduced into the insertion channel using the implant syringe.

Description

Implantatspritze Implant syringe
Die Erfindung betrifft eine Implantatspritze, aus deren Spritzennadel mittels eines Kolbens vorzugsweise ein langgestrecktes, strangförmiges Präparat mit einem Langzeitwirkstoff abgegeben wird. Meist wird ein solches Langzeitpräparat in die Bauchdecke eines Patienten gelegt, in die zuvor mittels der Spritzennadel der Implantatspritze ein Aufnahmekanal für das Präparat eingestochen wurde.The invention relates to an implant syringe, from the syringe needle of which an elongated, strand-like preparation with a long-term active ingredient is preferably dispensed by means of a piston. Such a long-term preparation is usually placed in the abdominal wall of a patient, into which a receiving channel for the preparation has previously been inserted using the syringe needle of the implant syringe.
Bisher wird dabei so vorgegangen, daß nach der Ausbildung des Einstichkanals der Kolben der Implantatspritze in der Spritzennadel vorgeschoben wird, während gleichzeitig die gesamte Im- plantspritze mit der Spritzennadel aus dem Einstichkanal zurückgezogen wird, wobei das Präparat langsam aus der Spritzennadel austritt und diese schließlich verläßt. Dabei besteht das Problem, daß der Vorschub des Kolbens und das Zurückziehen der Spritzennadel so aufeinander abgestimmt werden muß, daß das Präparat, bei dem es sich um einen harten Formkörper handelt, exakt in den Einstichkanal eingelegt wird. Wenn nämlich das Präparat schneller aus der Spritzennadel herausgedrückt wird, als diese in dem Einstichkanal zurückgezogen wird, wird das Präparat gewaltsam in das Gewebe der Bauchdecke gestoßen, was bei dem Patienten große Schmerzen hervorruft. Wird andererseits die Spritzennadel schneller zurückgezogen, als das Präparat aus dieser austritt, kann die Folge sein, daß die strangförmige Tablette nicht vollständig in den Einstichkanal aufgenommen wird.So far, the procedure has been such that, after the puncture channel has been formed, the plunger of the implant syringe is advanced into the syringe needle, while at the same time the entire implant syringe with the syringe needle is withdrawn from the puncture channel, the preparation slowly emerging from the syringe needle and finally leaving it . The problem here is that the advance of the plunger and the retraction of the syringe needle must be coordinated with one another in such a way that the preparation, which is a hard molded article, is inserted exactly into the puncture channel. If the preparation is pushed out of the syringe needle faster than it is withdrawn in the puncture channel, the preparation is pushed violently into the tissue of the abdominal wall, which causes great pain in the patient. On the other hand, the syringe needle is withdrawn faster than the preparation this emerges, the result may be that the strand-shaped tablet is not completely absorbed into the puncture channel.
Der vorliegenden Erfindung liegt die Aufgabe zugrunde, eine Implantatspritze anzugeben, bei der gewährleistet ist, daß das Präparat exakt in den Einstichkanal gelegt wird, wodurch dieser Vorgang -abgesehen von der Ausbildung des Einstichkanals- schmerzfrei erfolgt.The present invention has for its object to provide an implant syringe in which it is ensured that the preparation is placed exactly in the puncture channel, whereby this process - apart from the formation of the puncture channel - is painless.
Diese Aufgabe wird erfindungsgemäß durch die Merkmale des Patentanspruchs 1 gelöst.This object is achieved by the features of claim 1.
Vorteilhafte Ausgestaltungen der Erfindung sind in den Unteransprüchen gekennzeichnet.Advantageous embodiments of the invention are characterized in the subclaims.
Die erfindungsgemäße Implantatspritze hat einen Abstandhalter, der den Vorschub des Kolbens in die Spritzennadel derart begrenzt, daß zwischen der Austrittsöffnung der Spritzennadel und dem Kopfende des Kolbens in der vorgeschobenen Präparat-Abgabeposition ein Abstand verbleibt, der gleich der Länge des abzugebenden Präparates oder etwas größer als diese ist. Außerdem ist die Spritzennadel mittels eines Griffstücks in Richtung des Abstandhalters um eine Strecke zurückziehbar, die mindestens so groß ist wie die Länge des Präparats oder auch größer als diese.The implant syringe according to the invention has a spacer which limits the advance of the plunger into the syringe needle in such a way that a distance remains between the outlet opening of the syringe needle and the head end of the plunger in the advanced preparation-dispensing position, which is equal to or somewhat larger than the length of the preparation to be dispensed this is. In addition, the syringe needle can be withdrawn by a handle in the direction of the spacer by a distance which is at least as long as the length of the preparation or also greater than this.
Bei der erfindungsgemäßen Implantatspritze wird demnach in einem ersten Schritt nach dem Setzen der Spritze bzw. dem Ausbilden des Einstichkanals der Kolben bis zu dem durch den Abstandhalter gebildeten Anschlag vorgeschoben, wodurch die in der Implantatspritze befindliche strangförmige Tablette bis zu Nadelspitze vorgeschoben wird, woraufhin -bei unbeweglich gehaltenem Kolben- die Spritzennadel mittels einer Handhabe mindestes soweit zurückgezogen wird, bis das Präparat freiliegt. Hierdurch ist zu- verlässig gewährleistet, daß das strangförmige Präparat nicht über die Nadelspitze, d.h. über das Ende des Einstichkanals hinaus vorgeschoben wird, d.h. es ist unmöglich, den harten Tablettenstrang in das Gewebe des Patienten einzupressen.In the case of the implant syringe according to the invention, the plunger is thus advanced in a first step after the syringe has been set or the puncture channel has been formed, up to the stop formed by the spacer, as a result of which the strand-shaped tablet located in the implant syringe is advanced up to the needle tip, whereupon the syringe needle is held immovably by a handle at least until the preparation is exposed. This means reliably ensures that the strand-like preparation is not pushed past the needle tip, ie beyond the end of the puncture channel, ie it is impossible to press the hard tablet strand into the patient's tissue.
Da das Präparat durch den Vorschub des Kolbens in eine Position gebracht wird, in der es sich an der Nadelspitze und damit am Ende des Einstichkanals befindet, ist außerdem gewährleistet, daß es in seiner ganzen Länge in den Einstichkanal gelegt wird, da das Präparat nicht zurückgezogen wird, während es aus der Spritzennadel austritt. Statt dessen wird die Spritzennadel von dem Präparat zurückgezogen, während das letztere durch den Kolben in seiner Position gehalten wird. Während des Zurückziehens der Spritzennadel sollte die vordere Stirnfläche des den rückwärtigen Bereich der Spritzennadel umgebenden Spritzengehäuses in Kontakt mit der Haut des Patienten bleiben, wenn diese Stirnfläche des Gehäuses zur Begrenzung der Länge bzw. Tiefe des Einstichkanals dient, wie dies bevorzugt ist.Since the preparation is brought into a position by the advance of the plunger, in which it is located at the needle tip and thus at the end of the puncture channel, it is also ensured that the entire length of the specimen is placed in the puncture channel since the preparation is not withdrawn as it emerges from the syringe needle. Instead, the syringe needle is withdrawn from the preparation while the latter is held in position by the plunger. During the retraction of the syringe needle, the front end face of the syringe housing surrounding the rear region of the syringe needle should remain in contact with the patient's skin if this end face of the housing serves to limit the length or depth of the puncture channel, as is preferred.
Die erfindungsgemäße Implantatspritze besteht in einer bevorzugten Ausgestaltung der Erfindung im wesentlichen aus drei Hauptbestandteilen, nämlich aus dem Abstandhalter, der aus einer vorzugsweise im rechten Winkel zur Längsachse der Spritze verlaufenden Basisplatte und einer daran angesetzten, das oben erwähnte Spritzengehäuse bildenden Führungshülse besteht, deren vordere Stirnfläche die Einstichtiefe der Spritzennadel begrenzen sollte, ferner aus dem Griffstück, das als Handhabe bevorzugt zwei in einer parallelen Ebene zur Basisplatte des Abstandhalters liegende Laschen enthält, die von einer im wesentlichen rohrförmigen, sich in axialer Richtung der Spritze erstreckenden Nadelhalterung des Griffstücks abstehen, wobei die Nadelhalterung eine axiale Durchgangsbohrung enthält, in der die Spritzennadel sitzt, beispielsweise eingepreßt ist, sowie dem Kolben, der die Form eines langgestreckten dünnen Stabes hat und der mittig an einer Endplatte sitzt, an der eine den Endab - schnitt des Kolbens umgebende Hülse angeformt ist, die den Vorschub des Kolbens begrenzt, wenn ihre vordere Stirnseite auf die Basisplatte des Abstandhalters auftrifft.In a preferred embodiment of the invention, the implant syringe according to the invention essentially consists of three main components, namely the spacer, which consists of a base plate, preferably running at a right angle to the longitudinal axis of the syringe, and a guide sleeve attached to it and forming the above-mentioned syringe housing, the front end face of which should limit the puncture depth of the syringe needle, further from the handle, which preferably contains as a handle two tabs lying in a parallel plane to the base plate of the spacer, which protrude from a substantially tubular needle holder of the handle extending in the axial direction of the syringe, the Needle holder contains an axial through hole in which the syringe needle is seated, for example pressed, and the piston, which has the shape of an elongated thin rod and which sits centrally on an end plate on which a sleeve is formed which surrounds the end section of the piston and which limits the advance of the piston when its front end face hits the base plate of the spacer.
Im einzelnen wird mit Vorteil vorgeschlagen, daß der im wesentlichen rohrförmige mittige Ansatz des Griffstücks, der die Nadelhalterung bildet, eine axiale Durchgangsbohrung besitzt, in die die Spritzennadel eingreift. Die Spritzennadel erstreckt sich jedoch vorzugsweise nicht vollständige durch die Durchgangsbohrung der Nadelhalterung, sondern läßt einen rückwärtigen Endabschnitt der Durchgangsbohrung frei, die hier einen eingeschränkten freien Innendurchmesser hat, der etwas kleiner als der Innendurchmesser der Spritzennadel und -vor allem- etwas kleiner als der Außendurchmesser des strangförmigen Präparates ist. Der Innendurchmesser des Endabschnitts der Durchgangsbohrung kann dadurch verringert sein, daß einzelne Vorsprünge, die beispielsweise wulst- oder nasenförmig sein können, ein wenig nach innen vorstehen, wobei diese Vorsprünge so bemessen sind, daß eine in diesen Endabschnitt der Durchgangsbohrung eingreifende strangförmige Tablette daran gehindert ist, ohne Einwirkung des Kolbens in die Spritzennadel einzutreten und damit aus der Implantatspritze unbeabsichtigt herauszugleiten. Das Präparat ist jedoch nicht so fest in dem Endabschnitt der Durchgangsbohrung behalten, daß der durch den Kolben hervorgerufene Vorschub in die Spritzennadel behindert wird.In particular, it is advantageously proposed that the essentially tubular, central extension of the handle, which forms the needle holder, has an axial through-hole into which the syringe needle engages. However, the syringe needle preferably does not extend completely through the through hole of the needle holder, but leaves a rear end section of the through hole free, which here has a restricted free inside diameter which is somewhat smaller than the inside diameter of the syringe needle and, above all, somewhat smaller than the outside diameter of the strand-like preparation is. The inside diameter of the end section of the through-hole can be reduced in that individual projections, which can be, for example, bead-like or nose-shaped, protrude a little inwards, these projections being dimensioned such that a strand-shaped tablet engaging in this end section of the through-hole is prevented from doing so to enter the syringe needle without the action of the plunger and thus accidentally slide out of the implant syringe. However, the preparation is not kept so tightly in the end portion of the through hole that the advance caused by the piston into the syringe needle is impeded.
Das Griffstück hat als Handhabe zum Zurückziehen der Spritzennadel bevorzugt zwei von der rohrförmigen Nadelhaltung abstehende, einander gegenüberliegende Laschen, ohne daß die Erfindung auf diese Ausbildung beschränkt ist. Das rückwärtige Ende der im wesentlichen rohrförmigen Nadelhalterung ist zweckmäßigerweise mit einem ebenfalls im wesentlichen rohrförmigen Element, das der Aufnahme des strangförmigen Präparats dient, verbunden, wobei das Präparataufnahmeelement eine Durchgangsbohrung hat, die mit derjenigen der Nadelhalterung fluchet. Die beiden Kunststoffelemente können beispielsweise zusammengesteckt oder auf jede andere zweckmäßige Weise mit ihren Stirnseiten miteinander verbunden sein. Zweckmäßigerweise haben sie dieselbe Querschnittsform mit übereinstimmendem Außendurchmesser, wobei der Durchmesser der Durchgangsbohrung etwas größer als der Außendurchmesser des Präparats sein sollte.As a handle for retracting the syringe needle, the grip piece preferably has two tabs which protrude from the tubular needle holder and lie opposite one another, without the invention being restricted to this configuration. The rear end of the substantially tubular needle holder is expediently connected to a likewise essentially tubular element which serves to receive the strand-like preparation, the preparation receiving element having a through hole which is flush with that of the needle holder. The two plastic elements can, for example, be put together or connected to one another with their end faces in any other expedient way. Expediently, they have the same cross-sectional shape with a matching outer diameter, the diameter of the through hole being somewhat larger than the outer diameter of the preparation.
Zweckmäßigerweise wird das strangförmige Präparat in die Durchgangsbohrung des Präparataufnahmeelementes eingesetzt, bevor das auf die beschriebene Weise zusammengesetzte Griffstück mit dem Abstandhalter und seiner Führungshülse zusammengesetzt wird.The strand-like preparation is expediently inserted into the through bore of the preparation receiving element before the handle piece assembled in the manner described is assembled with the spacer and its guide sleeve.
Der Abstandhalter hat zweckmäßigerweise eine Basisplatte mit einer mittigen Bohrung, in der im Ausgangszustand der Implantatspritze das rückwärtige Ende des Präparataufnahmeelementes sitzt, und eine in axialer Richtung verlaufende Führungshülse, die im rechten Winkel von der Basisplatte absteht. Die Führungshülse weist bevorzugt zwei einander gegenüberliegende, in axialer Richtung durchgehende Schlitze auf, d.h. sie besteht aus zwei im Abstand voneinander angeordneten Führungshülsenabschnitten, wobei die Laschen des Griffstücks diese Schlitze durchgreifen und nach außen über die Führungshülse vorstehen, so daß sie von den Fingern eines Benutzers der Implantatspritze hintergriffen werden können, um die Spritzennadel zur Abgabe der Präparats zurück zu ziehen. Dies wird weiter unten noch näher beschrieben. In dem rückwärtigen Endabschnitt des Präparataufnahmeelementes sitzt zweckmäßigerweise ein Dichtring für den Kolben, der im Ausgangszustand der Spritze mit seinem vorderen Kopfende über eine kleine Strecke in den von dem Präparat freigelassenen Abschnitt der Durchgangsbohrung eingreift. Das Präparataufnahmeelement sitzt verschieblich in der mittigen Bohrung der Basisplatte des Abstandhalters. Nach der Abgabe des Präparats kann das Präparataufnahmeelement in voller Länge durch die Basisplatte des Abstandhalters hindurchgetreten sein, was weiter unten noch erläutert wird.The spacer expediently has a base plate with a central bore in which the rear end of the specimen receiving element is seated in the initial state of the implant syringe, and a guide sleeve which extends in the axial direction and projects at a right angle from the base plate. The guide sleeve preferably has two mutually opposite, through-going slots in the axial direction, that is, it consists of two spaced-apart guide sleeve sections, the tabs of the handle reaching through these slots and projecting outward beyond the guide sleeve so that they are from a user's fingers the implant syringe can be used to pull the syringe needle back to dispense the preparation. This is described in more detail below. In the rear end section of the specimen receiving element there is expediently a sealing ring for the plunger which, in the initial state of the syringe, engages with its front head end over a small distance in the section of the through hole left free by the specimen. The specimen receiving element is slidably seated in the central hole in the base plate of the spacer. After the preparation has been dispensed, the entire length of the preparation receiving element can have passed through the base plate of the spacer, which will be explained further below.
Der Kolben der Implantatspritze ist zweckmäßigerweise an einer Endplatte befestigt, an der die bereits oben erwähnte Hülse angeformt ist, die einen rückwärtigen Kolbenabschnitt umgibt. Diese Hülse hat einen Innendurchmesser, der größer als der Außendurchmesser des Präparataufnahmeelementes und gegebenenfalls des Nadelhalters ist. Beim Zurückziehen der Spritzennadel tritt das Präparataufnahmeelement durch die Basisplatte des Abstandstandhalters hindurch in den Innenraum der Hülse ein.The piston of the implant syringe is expediently fastened to an end plate on which the above-mentioned sleeve is formed, which surrounds a rear piston section. This sleeve has an inner diameter that is larger than the outer diameter of the specimen receiving element and possibly the needle holder. When the syringe needle is withdrawn, the specimen receiving element enters the interior of the sleeve through the base plate of the spacer.
Im Ausgangszustand der Implantatspritze ist die den rückwärtigen Endabschnitt des Kolbens umgebende Hülse zweckmäßigerweise von einem abnehmbaren Distanzelement umgeben, das mit einem Ende an der Basisplatte des Abstandhalters und mit dem anderen Ende an der Endplatte des Kolbens anliegt. Dieses abnehmbare Distanzelement, bei dem es sich beispielsweise um eine auf ganzer Länge aufgeschnittene Hülse handeln kann, verhindert einen unbeabsichtigten Vorschub des Kolbens vor Gebrauch der Implantatspritze.In the initial state of the implant syringe, the sleeve surrounding the rear end section of the plunger is expediently surrounded by a removable spacer element, which rests with one end on the base plate of the spacer and with the other end on the end plate of the plunger. This removable spacer element, which can be, for example, a sleeve cut open over its entire length, prevents the piston from being inadvertently advanced before the implant syringe is used.
Die erfindungsgemäße Implantatspritze wird folgendermaßen gehandhabt: Zunächst wird der Einstichkanal ausgebildet, indem die Spritzennadel soweit beispielsweise in die Bauchdecke eines Patienten eingestochen wird, bis die vordere Stirnkante der zweiteiligen Führungshülse des Abstandhalters auf der Haut des Patienten aufliegt. Anschließend wird das Distanzelement abge- nommen. Daraufhin wird der Kolben durch Ausübung eines Drucks auf die mit ihm verbundene Endplatte vorgeschoben, wobei die Basisplatte des Abstandhalters hintergriffen wird. Dieser Vorgang endet mit dem Auftreffen der vorderen Stirnkante der den Kolben umgebenden Hülse auf die Basisplatte des Abstandhalters. Das strangförmige Präparat ist dabei zur Austrittsöffnung der Spritzennadel vorgeschoben worden.The implant syringe according to the invention is handled as follows: First, the puncture channel is formed by inserting the syringe needle into the abdominal wall of a patient, for example, until the front end edge of the two-part guide sleeve of the spacer lies on the patient's skin. The spacer is then removed taken. The piston is then advanced by exerting pressure on the end plate connected to it, the base plate of the spacer being engaged behind. This process ends with the impact of the front end edge of the sleeve surrounding the piston on the base plate of the spacer. The strand-like preparation has been advanced to the outlet opening of the syringe needle.
Anschließend wird das Griffstück durch Hintergreifen seiner abstehenden Laschen bis zu einem Anschlag zurückgezogen. Als Anschlag kann das Auftreffen der rückwärtigen Stirnkante des Präparataufnahmeelementes auf die Kolben-Endplatte dienen. Die Erfindung ist hierauf nicht beschränkt, sondern es können auch beispielsweise die Laschen des Griffstücks auf einen Anschlag der Führungshülse oder auf die Basisplatte des Abstandhalters auftreffen. Bei Erreichen des Anschlags ist das Präparat abgelegt, so daß der noch über die Führungshülse hinausstehende Abschnitt der Spritzennadel aus dem Einstichkanal herausgezogen werden kann .The grip is then pulled back until it stops by reaching behind its protruding tabs. The impact of the rear end edge of the specimen receiving element on the piston end plate can serve as a stop. The invention is not limited to this, but for example the tabs of the handle can strike a stop of the guide sleeve or the base plate of the spacer. When the stop is reached, the preparation is deposited so that the section of the syringe needle that still protrudes beyond the guide sleeve can be pulled out of the puncture channel.
Die erfindungsgemäße Implantatspritze ist vorzugsweise eine Wegwerf-Spritze für einmaligen Gebrauch, ohne daß die Erfindung hierauf beschränkt ist. Die einzelnen Bestandteile bestehen vorzugsweise aus Kunststoff, mit Ausnahme der Spritzennadel, die zweckmäßigerweise aus Metall besteht. Die Nadelhalterung kann beispielsweise aus einem Polypropylen oder Polyäthylen bestehen, wobei dieses Material zur Ausbildung der Haltenasen für das Präparat geeignet ist. Das anschließende Präparataufnahmeelement besteht zweckmäßigerweise aus durchsichtigem Polykarbonat . Der Dichtungsring des Abstandhalters, für den Polypropylen oder Polyäthylen beispielsweise geeignete Materialien sind, besteht zweckmäßigerweise aus einem Elastomer. Die Erfindung ist natürlich nicht auf diese Materialien beschränkt. Das abzulegende Langzeitpräparat muß nicht unbedingt eine durchgehende Strangform haben, obwohl diese meist der Fall ist. Die Implantatspritze ist aber ebenso zum Ablegen mehrerer hintereinander angeordneter Tabletten beispielsweise in Kugelform verwendbar .The implant syringe according to the invention is preferably a disposable syringe for single use, without the invention being restricted to this. The individual components are preferably made of plastic, with the exception of the syringe needle, which is expediently made of metal. The needle holder can for example consist of a polypropylene or polyethylene, this material being suitable for forming the holding lugs for the preparation. The subsequent specimen receiving element expediently consists of transparent polycarbonate. The sealing ring of the spacer, for which polypropylene or polyethylene are suitable materials, for example, expediently consists of an elastomer. The invention is of course not limited to these materials. The long-term preparation to be discarded does not necessarily have to have a continuous strand form, although this is usually the case. However, the implant syringe can also be used to place several tablets arranged one behind the other, for example in spherical form.
Weitere Einzelheiten der Erfindung ergeben sich aus der nachfolgenden Beschreibung einer bevorzugte Ausführungsform der Erfindung. Dabei zeigen;Further details of the invention result from the following description of a preferred embodiment of the invention. Show;
Fig. 1 eine Implantatspritze im Ausgangszustand;1 shows an implant syringe in the initial state;
Fig. 2 einen Schnitt durch die Implantatspritze gemäß Fig. 1 entlang der Linie II-II in Fig. 1;FIG. 2 shows a section through the implant syringe according to FIG. 1 along the line II-II in FIG. 1;
Fig. 3 die Implantatspritze gemäß Fig. 1 in dem Zustand, in dem das Präparat zur Nadelspitze vorgeschoben ist undFig. 3 shows the implant syringe of FIG. 1 in the state in which the preparation is advanced to the needle tip and
Fig. 4 die Implantatspritze im zurückgezogenen Zustand der Nadel.Fig. 4 shows the implant syringe in the retracted state of the needle.
Die in den Figuren dargestellte Implantat- oder Depotspritze 1 enthält ein insgesamt mit 2 bezeichnetes Griffstück, das einstückig aus einer zentralen röhr- oder hülsenförmigen Nadelhalterung 3 und davon senkrecht abstehenden Laschen 4 besteht. Die Nadelhalterung 3 ist an ihrem von den Laschen 4 nach vorne weisenden Abschnitt leicht konisch zulaufend ausgebildet.The implant or depot syringe 1 shown in the figures contains a handle, generally designated 2, which consists in one piece of a central tubular or sleeve-shaped needle holder 3 and tabs 4 projecting vertically therefrom. The needle holder 3 is slightly tapered on its section facing forward from the tabs 4.
In der Durchgangsbohrung 5 der Nadelhalterung 3 sitzt eine vorzugsweise aus Metall bestehende Spritzennadel 6, die sich nicht vollständig durch die Durchgangsbohrung 5 erstreckt, sondern einen Endabschnitt 7 der Durchgangsbohrung 5 freiläßt. Im Bereich des Endabschnitts 7 ist der freie Innenraum der Durchgangsbohrung 5 durch einwärts vorstehende Nasen oder Wülste soweit verringert, daß ein strangförmiges Präparat 8 dort in einem leichten Klemmsitz gehalten ist, der verhindert, daß das Präparat 8 selbsttätig durch die Spritzennadel 6 die Implantatspritze verläßt.In the through bore 5 of the needle holder 3 there is a syringe needle 6, preferably made of metal, which does not extend completely through the through bore 5, but leaves an end section 7 of the through bore 5 free. In the area of the end section 7 is the free interior of the through hole 5 by inwardly projecting lugs or beads reduced to such an extent that a strand-like preparation 8 is held there in a slight clamping fit, which prevents the preparation 8 from automatically leaving the implant syringe through the syringe needle 6.
Die Nadelhalterung 3 ist mit einem Präparataufnahmeelement 9 beispielsweise durch eine Steckverbindung verbunden, das denselben Außendurchmesser hat wie der anschließende Abschnitt der Nadelhalterung 3. Die Durchgangsbohrung 10 des Präparataufnahmeelementes 9 fluchtet mit der Durchgangsbohrung 5 der Nadelhalterung 3.The needle holder 3 is connected to a specimen receiving element 9, for example by a plug-in connection, which has the same outer diameter as the adjoining section of the needle holder 3. The through hole 10 of the specimen receiving element 9 is aligned with the through hole 5 of the needle holder 3.
In dem rückwärtigen Endabschnitt des Präparataufnahmeelementes 9 sitzt ein Dichtungsring 11 aus einem Elastomer.A sealing ring 11 made of an elastomer sits in the rear end section of the specimen receiving element 9.
In dem Zustand gemäß Fig. 1 sitzt der Endabschnitt des Präparataufnahmeelementes 9 in einer mittigen Durchgangsbohrung 12 der Basisplatte 3 eines insgesamt mit 14 bezeichneten Abstandhalters. Der Abstandhalter 14 enthält außerdem eine einstückig angeformte Führungshülse, die aus zwei Führungshülsenabschnitten 15 besteht, zwischen denen zwei diametral gegenüberliegende Zwischenräume bzw. Schlitze 16 offenbleiben. Diese beiden Schlitze 16 werden von den Laschen 4 des GriffStücks 2 durchgriffen. Das Griffstück 2 ist damit in axialer Richtung auf die Basisplatte 13 des Abstandhalters 14 hin verschiebbar, wobei die Laschen 4 in den Schlitzen 16 der Führungshülse 15, 15 geführt werden.In the state according to FIG. 1, the end section of the specimen receiving element 9 is seated in a central through-bore 12 of the base plate 3 of a spacer, generally designated 14. The spacer 14 also contains an integrally formed guide sleeve, which consists of two guide sleeve sections 15, between which two diametrically opposite spaces or slots 16 remain open. These two slots 16 are penetrated by the tabs 4 of the handle piece 2. The handle 2 can thus be moved in the axial direction towards the base plate 13 of the spacer 14, the tabs 4 being guided in the slots 16 of the guide sleeve 15, 15.
In dem in Fig. 1 dargestellten Zustand sitzt das Kopfende eines langgestreckten stabförmigen Kolbens 17 in dem Dichtungsring 11. Der Kolben 17 fluchtet mit dem Präparat 8, das wiederum mit der Spritzennadel 6 fluchtet. Der Kolben 17 ist an einer Endplatte 18 befestigt, die einstük- kig mit einer Hülse 18 ausgebildet ist, die den rückwärtigen Endbereich des Kolbens 17 mit einem solchen Abstand umgibt, daß das Präparataufnahmeelement 9 in den Zwischenraum zwischen der Hülse 18 und dem Kolben 17 eintreten kann, wie Fig. 4 zeigt.In the state shown in FIG. 1, the head end of an elongated rod-shaped piston 17 is seated in the sealing ring 11. The piston 17 is aligned with the preparation 8, which in turn is aligned with the syringe needle 6. The piston 17 is fastened to an end plate 18 which is formed in one piece with a sleeve 18 which surrounds the rear end region of the piston 17 with such a distance that the specimen receiving element 9 enter the space between the sleeve 18 and the piston 17 can, as Fig. 4 shows.
Die Hülse 18 ist von einer über ihre gesamte Länge aufgeschlitzten Distanzhülse 19 umgeben, die an der Basisplatte 13 und der Endplatte 16 anliegt und verhindert, daß der Kolben 17 vorgeschoben wird. Die Distanzhülse 19 wird abgenommen, bevor der Kolben 17 vorgeschoben wird.The sleeve 18 is surrounded by a slotted spacer 19 over its entire length, which rests on the base plate 13 and the end plate 16 and prevents the piston 17 from being advanced. The spacer sleeve 19 is removed before the piston 17 is advanced.
Die Implantatspritze 1 wird in dem in Fig. 1 dargestellten Zustand z.B. in die Bauchdecke eines Patienten eingestochen, bis die vordere Stirnkante 20 der Führungshülse 15 an der Haut des Patienten anliegt. Nach Abnahme der Distanzhülse 19 wird nun - wie Fig. 3 zeigt- der Kolben 17 mittels der Endplatte 16 soweit in der Figur nach links vorgeschoben, bis die vordere Stirnkante 21 der Hülse 18 an der Basisplatte 13 anliegt. Hierdurch schiebt der Kolben 17 das Präparat 8 in die Spritzennadel 6 hinein und darin bis zur Nadelspitze 22 vor.The implant syringe 1 is in the state shown in Fig. 1 e.g. stabbed into the abdominal wall of a patient until the front end edge 20 of the guide sleeve 15 abuts the patient's skin. After removal of the spacer sleeve 19, the piston 17 is - as shown in FIG. 3 - pushed to the left in the figure by means of the end plate 16 until the front end edge 21 of the sleeve 18 bears against the base plate 13. As a result, the piston 17 pushes the preparation 8 into the syringe needle 6 and forwards up to the needle tip 22.
Anschließend wird durch Ergreifen der Laschen 4 das Griffstück 2 mit der Spritzennadel 6 langsam in Richtung der Basisplatte 13 des Abstandhalters 14 zurückgezogen, bis die rückwärtige Stirnkante 23 des Präparataufnahmeelementes 9 an der Endplatte 16 anliegt. Dieser Rückwärtshub des GriffStücks 2 ist so bemessen, daß das Kopfende des Kolbens 17 die Nadelspitze erreicht oder überragt, so daß das Präparat 8 vollständig freigegeben ist. Die Spritze kann nun von dem Patienten entfernt werden, wobei das Präparat 8 in dem Einstichkanal zurückbleibt. Die Implantatspritze 1 wird zweckmäßigerweise so montiert, daß nach dem Zusammenstecken des GriffStücks 2 mit dem Präparataufnahmeelement 9 das Präparat 8 in die Durchgangsbohrung 10 eingesetzt wird. Anschließend wird diese Anordnung mit dem Abstandhalter 14 zusammengesetzt, woraufhin der Kolben 17 in den Endbereich der Bohrung 10 eingesetzt und die Distanzhülse 9 angebracht wird. Then, by gripping the tabs 4, the handle 2 with the syringe needle 6 is slowly withdrawn in the direction of the base plate 13 of the spacer 14 until the rear end edge 23 of the specimen receiving element 9 bears against the end plate 16. This backward stroke of the handle piece 2 is dimensioned such that the head end of the piston 17 reaches or projects above the needle tip, so that the preparation 8 is completely released. The syringe can now be removed from the patient, the preparation 8 remaining in the puncture channel. The implant syringe 1 is expediently mounted in such a way that, after the handle piece 2 has been plugged together with the specimen receiving element 9, the specimen 8 is inserted into the through bore 10. This arrangement is then assembled with the spacer 14, whereupon the piston 17 is inserted into the end region of the bore 10 and the spacer sleeve 9 is attached.

Claims

Patentansprüche claims
1. Implantatspritze, mit einer Spritzennadel und einem Kolben, d a d u r c h g e k e n n z e i c h n e t, daß der Vorschub des Kolbens (17) in die Spritzennadel (6) durch einen Abstandhalter (14) derart begrenzt ist, daß zwischen der Austrittsöffnung der Spritzennadel (6) und dem Kopfende des Kolbens (17) ein Abstand verbleibt, der mindestens gleich der Länge des abzugebenden Präparats (8) ist, und daß die Spritzennadel (6) mittels eines GriffStücks (2) in Richtung des Abstandhalters (14) mindestens um eine mit der Länge des Präparats (8) übereinstimmende Strecke zurückziehbar ist.1. Implant syringe, with a syringe needle and a piston, characterized in that the feed of the piston (17) into the syringe needle (6) is limited by a spacer (14) such that between the outlet opening of the syringe needle (6) and the head end of the Piston (17) remains a distance that is at least equal to the length of the preparation (8) to be dispensed, and that the syringe needle (6) by means of a handle (2) in the direction of the spacer (14) by at least one with the length of the preparation ( 8) Matching distance is retractable.
2. Implantatspritze nach Anspruch 1, dadurch gekennzeichnet, daß die Spritzennadel (6) fest in der axialen Durchgangsbohrung (5) einer im wesentlichen rohrförmigen mittigen Nadelhalterung (3) des GriffStücks (2) sitzt.2. Implant syringe according to claim 1, characterized in that the syringe needle (6) sits firmly in the axial through bore (5) of an essentially tubular central needle holder (3) of the handle piece (2).
3. Implantatspritze nach Anspruch 2, dadurch gekennzeichnet, daß der freie Innendurchmesser des Endabschnitts der Durchgangsbohrung (5) hinter dem rückwärtigen Ende der Spritzennadel (6) etwas kleiner als der Außendurchmesser des Präparats (8) ist.3. Implant syringe according to claim 2, characterized in that the free inner diameter of the end portion of the through hole (5) behind the rear end of the syringe needle (6) is slightly smaller than the outer diameter of the preparation (8).
4. Imlantatspritze nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß das Griffstück (2) zwei von der Nadelhalterung (3) abstehende, einander gegenüberliegende Laschen (4) aufweist.4. implant syringe according to one of claims 1 to 3, characterized in that the handle (2) has two from the needle holder (3) projecting, opposite tabs (4).
5. Implantatspritze nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß der Abstandhalter (14) eine mit einer mittigen Bohrung (12) versehene Basisplatte (13) und eine in axialer Rrchtung verlaufende Führungshülse (15) aufweist. 5. Implant syringe according to one of claims 1 to 4, characterized in that the spacer (14) has a base plate (13) provided with a central bore (12) and a guide sleeve (15) extending in the axial direction.
6. Implantatspritze nach Anspruch 5, dadurch gekennzeichnet, daß die Führungshülse zwei einander gegenüberliegende, in axialer Richtung durchgehende Schlitze6. Implant syringe according to claim 5, characterized in that the guide sleeve has two opposing slots which are continuous in the axial direction
(16) aufweist, die von den Laschen (4) des GriffStücks (2) durchgriffen sind.(16) which are penetrated by the tabs (4) of the handle (2).
7. Implantatspritze nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, daß das rückwärtige Ende der Nadelhaite- rug (3) mit einem im wesentlichen rohrförmigen Präparataufnahmeelement (9) verbunden ist, dessen Durchgangbohrung (10) mit derjenigen der Nadelhalterung (3) fluchtet.7. Implant syringe according to one of claims 1 to 6, characterized in that the rear end of the Nadelhaite- rug (3) is connected to a substantially tubular preparation receiving element (9), the through bore (10) with which the needle holder (3) is aligned .
8. Implantatspritze nach Anspruch 7, dadurch gekennzeichnet, daß in dem rückwärtigen Endabschnitt des Präparataufnahmeelementes (8) ein Dichtring (11) für den Kolben8. Implant syringe according to claim 7, characterized in that in the rear end portion of the specimen receiving element (8) a sealing ring (11) for the piston
(17) sitzt.(17) sits.
9. Implantatspritze nach Anspruch 7 oder 8, dadurch gekennzeichnet, daß das Präparataufnahmeelement (8) verschieblich in der Bohrung (12) der Basisplatte (13) sitzt.9. Implant syringe according to claim 7 or 8, characterized in that the specimen receiving element (8) is slidably seated in the bore (12) of the base plate (13).
10. Implantatspritze nach einem der Ansprüche 1 bis 9, dadurch gekennzeichnet, daß der Kolben an einer Endplatte (16) befestigt ist, an der eine einen rückwärtigen Kolbenabschnitt umgebende Hülse (18) angeformt ist, deren Innendurchmesser größer als der Außendurchmesser des Präparataufnahmeelementes (9) ist.10. Implant syringe according to one of claims 1 to 9, characterized in that the piston is fastened to an end plate (16) on which a sleeve (18) surrounding a rear piston section is formed, the inside diameter of which is larger than the outside diameter of the specimen receiving element (9 ) is.
11. Implantatspritze nach Anspruch 10, dadurch gekennzeichnet, daß die Hülse (18) von einer abnehmbaren Distanzhülse (19) umgeben ist, die in der zurückgezogenen Ausgangslage des Kolbens (17) an der Basisplatte (13) und an der Endplatte (16) anliegt. 11. Implant syringe according to claim 10, characterized in that the sleeve (18) is surrounded by a removable spacer sleeve (19) which bears against the base plate (13) and the end plate (16) in the retracted initial position of the piston (17) .
EP98945024A 1997-08-08 1998-07-22 Implant syringe Withdrawn EP1001826A1 (en)

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DE19734385A DE19734385C1 (en) 1997-08-08 1997-08-08 Implant syringe
DE19734385 1997-08-08
PCT/DE1998/002057 WO1999007434A1 (en) 1997-08-08 1998-07-22 Implant syringe

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EP1001826A1 true EP1001826A1 (en) 2000-05-24

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JP (1) JP2001513375A (en)
AU (1) AU729686B2 (en)
CA (1) CA2297895A1 (en)
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WO1999007434A1 (en) 1999-02-18
CA2297895A1 (en) 1999-02-18
DE19734385C1 (en) 1999-02-18
US6478768B1 (en) 2002-11-12
AU9252998A (en) 1999-03-01
AU729686B2 (en) 2001-02-08
JP2001513375A (en) 2001-09-04

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