EP0983296A4 - Rezeptoren für tgf beta related neurotrophic factors - Google Patents
Rezeptoren für tgf beta related neurotrophic factorsInfo
- Publication number
- EP0983296A4 EP0983296A4 EP98918515A EP98918515A EP0983296A4 EP 0983296 A4 EP0983296 A4 EP 0983296A4 EP 98918515 A EP98918515 A EP 98918515A EP 98918515 A EP98918515 A EP 98918515A EP 0983296 A4 EP0983296 A4 EP 0983296A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- tgf
- receptors
- beta
- factors associated
- neurotrophic factors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108010025020 Nerve Growth Factor Proteins 0.000 title 1
- 102000007072 Nerve Growth Factors Human genes 0.000 title 1
- 239000003900 neurotrophic factor Substances 0.000 title 1
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4400797P | 1997-04-17 | 1997-04-17 | |
| US44007P | 1997-04-17 | ||
| US85998897A | 1997-05-21 | 1997-05-21 | |
| US859988 | 1997-05-21 | ||
| PCT/US1998/007996 WO1998046622A1 (en) | 1997-04-17 | 1998-04-16 | RECEPTORS FOR TGF-β-RELATED NEUROTROPHIC FACTORS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0983296A1 EP0983296A1 (de) | 2000-03-08 |
| EP0983296A4 true EP0983296A4 (de) | 2002-11-06 |
Family
ID=26721078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP98918515A Withdrawn EP0983296A4 (de) | 1997-04-17 | 1998-04-16 | Rezeptoren für tgf beta related neurotrophic factors |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0983296A4 (de) |
| AU (1) | AU748639B2 (de) |
| CA (1) | CA2291705A1 (de) |
| NZ (1) | NZ501423A (de) |
| WO (1) | WO1998046622A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6696259B1 (en) | 1995-11-13 | 2004-02-24 | Licentia Ltd. | Assays using glial cell line-derived neurotrophic factor receptors |
| CA2290426A1 (en) * | 1997-05-22 | 1998-11-26 | Carlos F. Ibanez | Glial cell line-derived neurotrophic factor receptors |
| WO2000050592A1 (en) * | 1999-02-24 | 2000-08-31 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| WO2017152105A1 (en) * | 2016-03-04 | 2017-09-08 | Ngm Biopharmaceuticals, Inc. | Compositions and methods for modulating body weight |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997044356A2 (en) * | 1996-05-08 | 1997-11-27 | Biogen, Inc. | RET LIGAND (RetL) FOR STIMULATING NEURAL AND RENAL GROWTH |
| WO1998036072A1 (en) * | 1997-02-18 | 1998-08-20 | Genentech, Inc. | Neurturin receptor |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5739307A (en) * | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
| US5641750A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product |
-
1998
- 1998-04-16 EP EP98918515A patent/EP0983296A4/de not_active Withdrawn
- 1998-04-16 WO PCT/US1998/007996 patent/WO1998046622A1/en not_active Ceased
- 1998-04-16 NZ NZ501423A patent/NZ501423A/en unknown
- 1998-04-16 AU AU71422/98A patent/AU748639B2/en not_active Ceased
- 1998-04-16 CA CA002291705A patent/CA2291705A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997044356A2 (en) * | 1996-05-08 | 1997-11-27 | Biogen, Inc. | RET LIGAND (RetL) FOR STIMULATING NEURAL AND RENAL GROWTH |
| WO1998036072A1 (en) * | 1997-02-18 | 1998-08-20 | Genentech, Inc. | Neurturin receptor |
Non-Patent Citations (4)
| Title |
|---|
| BALOH ROBERT H ET AL: "TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret.", NEURON, vol. 18, no. 5, 1997, pages 793 - 802, XP002210548, ISSN: 0896-6273 * |
| DATABASE EMBL [online] 21 June 1996 (1996-06-21), HILLIER L. ET AL., XP002210549, retrieved from EBI Database accession no. W73681 * |
| DATABASE EMBL [online] 21 June 1996 (1996-06-21), HILLIER L. ET AL., XP002210550, retrieved from EBI Database accession no. W73633 * |
| See also references of WO9846622A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ501423A (en) | 2002-02-01 |
| WO1998046622A1 (en) | 1998-10-22 |
| AU7142298A (en) | 1998-11-11 |
| CA2291705A1 (en) | 1998-10-22 |
| EP0983296A1 (de) | 2000-03-08 |
| AU748639B2 (en) | 2002-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 19991214 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
| RTI1 | Title (correction) |
Free format text: RECEPTORS FOR TGF-BETA-RELATED NEUROTROPHIC FACTORS |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20020923 |
|
| AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20031031 |