EP0963440A4 - Verbessertes verfahren zur transduktion von zellen - Google Patents

Verbessertes verfahren zur transduktion von zellen

Info

Publication number
EP0963440A4
EP0963440A4 EP97950669A EP97950669A EP0963440A4 EP 0963440 A4 EP0963440 A4 EP 0963440A4 EP 97950669 A EP97950669 A EP 97950669A EP 97950669 A EP97950669 A EP 97950669A EP 0963440 A4 EP0963440 A4 EP 0963440A4
Authority
EP
European Patent Office
Prior art keywords
improved methods
transducing cells
transducing
cells
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97950669A
Other languages
English (en)
French (fr)
Other versions
EP0963440A1 (de
Inventor
Isaiah J Fidler
Zhongyun Dong
Rakesh Kumar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Nebraska
University of Texas System
Original Assignee
University of Nebraska
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Nebraska, University of Texas System filed Critical University of Nebraska
Publication of EP0963440A1 publication Critical patent/EP0963440A1/de
Publication of EP0963440A4 publication Critical patent/EP0963440A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP97950669A 1996-11-20 1997-11-19 Verbessertes verfahren zur transduktion von zellen Withdrawn EP0963440A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3133096P 1996-11-20 1996-11-20
US31330P 1996-11-20
PCT/US1997/021475 WO1998022605A1 (en) 1996-11-20 1997-11-19 Improved methods for transducing cells

Publications (2)

Publication Number Publication Date
EP0963440A1 EP0963440A1 (de) 1999-12-15
EP0963440A4 true EP0963440A4 (de) 2004-12-29

Family

ID=21858846

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97950669A Withdrawn EP0963440A4 (de) 1996-11-20 1997-11-19 Verbessertes verfahren zur transduktion von zellen

Country Status (4)

Country Link
EP (1) EP0963440A4 (de)
JP (1) JP2001505205A (de)
CA (1) CA2275438A1 (de)
WO (1) WO1998022605A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004016021A (ja) 2002-06-12 2004-01-22 Japan Science & Technology Corp 抗体および阻害剤並びにそれを用いた形質転換方法および形質転換キット

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4442587A1 (de) * 1994-11-30 1996-08-01 Boehringer Ingelheim Int Verfahren zum Einbringen von Fremdmaterial in höhere eukaryotische Zellen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4987071A (en) * 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5656465A (en) * 1994-05-04 1997-08-12 Therion Biologics Corporation Methods of in vivo gene delivery
US5626862A (en) * 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
US5552309A (en) * 1994-09-30 1996-09-03 Indiana University Foundation Use of polyols for improving the introduction of genetic material into cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4442587A1 (de) * 1994-11-30 1996-08-01 Boehringer Ingelheim Int Verfahren zum Einbringen von Fremdmaterial in höhere eukaryotische Zellen

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1988, SHIROKI K ET AL: "ACTIVATION OF THE HUMAN BETA INTERFERON GENE BY THE ADENOVIRUS TYPE 12 E1B GENE", XP002285026, Database accession no. PREV198885057675 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1992, LALLEMAND C ET AL: "AN ANTISENSE INTERFERON-BETA RNA ABOLISHES REPRESSION OF C-FOS GENE EXPRESSION", XP002283638, Database accession no. PREV199294039408 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1992, NIELSCH U ET AL: "INDUCED EXPRESSION OF THE ENDOGENOUS BETA INTERFERON GENE IN ADENOVIRUS TYPE 5-TRANSFORMED RAT FIBROBLASTS", XP002285025, Database accession no. PREV199293135844 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1994, NICKOLAUS PETER ET AL: "Inhibition by interleukin-4 of constitutive beta interferon synthesis in mouse macrophages", XP002283639, Database accession no. PREV199497512589 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1997, DONG ZHONGYUN ET AL: "Neutralization of endogenous interferon-beta increases the efficiency of adenoviral vector-mediated gene transduction", XP002283640, Database accession no. PREV199799707380 *
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, vol. 17, no. 7, 1997, pages 401 - 407, ISSN: 1079-9907 *
JOURNAL OF VIROLOGY, vol. 62, no. 1, 1988, pages 325 - 330, ISSN: 0022-538X *
JOURNAL OF VIROLOGY, vol. 66, no. 4, 1992, pages 1884 - 1890, ISSN: 0022-538X *
JOURNAL OF VIROLOGY, vol. 68, no. 10, 1994, pages 6763 - 6766, ISSN: 0022-538X *
ONCOGENE, vol. 7, no. 6, 1992, pages 1109 - 1118, ISSN: 0950-9232 *
See also references of WO9822605A1 *

Also Published As

Publication number Publication date
CA2275438A1 (en) 1998-05-28
EP0963440A1 (de) 1999-12-15
WO1998022605A1 (en) 1998-05-28
JP2001505205A (ja) 2001-04-17

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19990621

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

Effective date: 20041111

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20060314