EP0957883B1 - Adapter for extracting a liquid from a container closed with a stopper - Google Patents

Adapter for extracting a liquid from a container closed with a stopper Download PDF

Info

Publication number
EP0957883B1
EP0957883B1 EP19960945696 EP96945696A EP0957883B1 EP 0957883 B1 EP0957883 B1 EP 0957883B1 EP 19960945696 EP19960945696 EP 19960945696 EP 96945696 A EP96945696 A EP 96945696A EP 0957883 B1 EP0957883 B1 EP 0957883B1
Authority
EP
European Patent Office
Prior art keywords
adapter
stopper
adaptor
characterised
funnel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP19960945696
Other languages
German (de)
French (fr)
Other versions
EP0957883A2 (en
Inventor
Bernd GRÄF
Werner Mrotzek
Ingoberth SCHÖNKE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Intellectual Property GmbH
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19540476 priority Critical
Priority to DE19540476 priority
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Priority to PCT/DE1996/002027 priority patent/WO1997015267A2/en
Publication of EP0957883A2 publication Critical patent/EP0957883A2/en
Application granted granted Critical
Publication of EP0957883B1 publication Critical patent/EP0957883B1/en
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096Combination of a vial and a syringe for transferring or mixing their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00General characteristics or adaptations
    • A61J2200/10Coring prevention means, e.g. for plug or septum piecing members

Abstract

An adapter is disclosed for extracting a liquid from a container closed with a stopper or for filling this container closed by a stopper retained by a flange. The adapter has at least one spike at its front end for piercing through the stopper, a connector with an inner cone at its rear end for coupling medical apparatus and a flat gripping element in the intermediate area to facilitate mounting the adapter. A funnel open towards the rear end of the adapter is arranged on the connector. In addition, an elastic centring and holding element is arranged towards the front end of the adapter on the gripping element. The inner contour of the centring and holding element corresponds at least in sections approximately to the outer contour of the flange that retains the stopper on the injection container. The inner contour also has locking elements that engage at least sections of the flange. This adapter may be used to extract liquid from a container closed with a stopper or to fill the container with a liquid by means of a standard syringe. It allows liquids to be transferred in a quick and reliable manner, without any risk of injury and with little effort.

Description

The present invention relates to an adapter for removal a liquid from a sealed with a stopper Container or for filling this container, which means a stopper fixed by a crimp cap is, with at least one partially hollow, with at least one Nozzle provided at the front end for piercing the Plug, a connecting part with an inner cone on the rear End for coupling medical devices and a flat Handle element to facilitate the adaptation process in between lying area.

Such adapters or withdrawal cannulas, cf. EP 0 499 481 A1 and WO 93/24095 - which forms the basis of the preamble of claim 1 - are used in the medical field, to i.a. commercially available infusion sets on infusion bottles to be able to connect. To do this, the adapters usually have a lockable taper connection according to DIN 13 090 part 2. Das Connect the infusion sets to the infusion bottles is done by trained personnel who have no problems the stopper of the infusion bottles with the adapter to pierce and connect the cutlery to the adapter. However, it is very difficult for an inexperienced person to use the infusion bottle to couple to the adapter. With an adapter that with the help of locking elements the crimp cap of the infusion bottle reaches behind, the thorn must stop the rubber plug at that moment pierce, in which the locking elements on the edge of Crimp cap come to rest to be pushed outwards. Especially in the initial phase of puncturing, if so a lot of power is needed to find the right one aligning adapter and infusion bottle the spread locking elements quite unstable on the upper outer edge the crimp cap. Even if the Operator gets lost between adapter and container. As a result, at least one locking element extends far outwards bent, possibly under cancel, while usually at least one locking element returns to its starting position and further postponement prevented by tilting.

In the event that from an infusion bottle, for example a partial quantity is to be drawn onto a syringe no adapter used. Rather, a cannula is placed on the syringe with which the stopper of the infusion bottle is attached is punctured. This procedure requires one certain routine and a steady hand. The suction is also carried out the liquid through the cannula is relatively slow because the free cannula cross-section is very small.

It is particularly difficult to wind up medical devices Preparations whose active ingredients are available as lyophilisates. For example motor-impaired MS patients need such Preparations for self-medication. Such a drug is stored in two size R2 infusion bottles. The first infusion bottle contains saline while the second infusion bottle contains the lyophilisate. The patient so far taken with a disposable syringe with attached Cannulae the saline solution from the first infusion bottle. The He injects the contents of the syringe into the second infusion bottle.

When doing so, he must make sure that the saline solution is not direct strikes the lyophilisate, otherwise a lump is inevitable is. The solution of saline and lyophilisate after shaking the second infusion bottle taken to be finally administered.

An aid for placing the disposable syringe on the infusion bottle offers an adapter known from WO 95/07066. This adapter is used as a guide for the disposable syringe on the Infusion bottle attached. The cannula of the disposable syringe pierces the straight when inserted into the adapter Closure of the infusion bottle. An inexperienced in handling syringes or a motor-impaired patient finds it difficult to use the single-use syringe not to tilt when inserted into the adapter. On Tilting will break the cannula. Even if the cannula is correctly inserted into the infusion bottle Lyophilisates still have the above-mentioned risk of clumping.

The present invention is therefore based on the problem to create an adapter with the help of which a liquid via a standardized syringe and one with a stopper Container removed as well as filled can. The transfer process should also be done by an inexperienced person fast, reliable, without any risk of injury and without greater effort can be performed. Furthermore should the risk of contamination should be as small as possible. Moreover are those known from the prior art Disadvantages are avoided.

The problem is solved by the features of the characterizing part of claim 1.

The elastic centering and gripping part is for example a thin-walled sleeve that emerges directly from the basic element. The inside diameter of the sleeve is slightly larger than the outside diameter of the stopper on the infusion bottle fixing crimp cap. There are three or inside the sleeve four individual, protruding locking elements in one arranged parallel to the base plate. The distance between the base plate and the locking element level is slight greater than the height of the crimp cap. The pod itself is several Extended millimeters beyond the locking elements. she is included - also to minimize the risk of injury - a few millimeters longer than the mandrel of the adapter. consequently the sleeve centers the adapter when it is placed on the infusion bottle cap. Only when the sleeve is the crimp cap the mandrel tip is almost completely surrounded or covered on the stopper. As soon as the tip of the mandrel pierces the stopper has, the locking elements on the top of the Crimp cap. If the adapter is pushed open further the locking elements pushed outwards. This deforms the thin-walled sleeve elastic. Reached in the locking element level they have a polygonal cross-section during sliding open. After fully sliding open the Locking elements the lower edge of the crimp cap, the sleeve returns to its cylindrical shape.

Instead of a sleeve with the molded locking elements can also individual cantilever arms arranged on the base element are used become. The one-part or multi-part centering and gripping part can also be designed so that after complete at least partially put on the infusion bottle is plastically deformed.

Furthermore, the centering and gripping part can be extended so far be that it is the cylindrical outer surface of the corresponding Infusion bottle partially covered or that the infusion bottle completely disappears into it. The whole serves here Bottle body as a centering aid.

Furthermore, the infusion bottle can also be attached and pre-latched adapter so that when Preparation and administration of the preparation, putting on and There is no need to center the adapter.

The one arranged on the other side of the grip element an inner cone equipped connecting part enables a easy coupling with an outer cone as a connecting part provided syringe. The syringe's outer cone slides along the inner funnel contour in the on the Funnel connecting standardized inner cone. By applying A low axial force creates a tight cone connection. The syringe forms together with the infusion bottle via the adapter a cohesive by positive and positive locking Unit that is stable in every position. For filling the syringe or to empty the respective infusion bottle the unit can only be held by the syringe barrel be brought into the winding position. The emptying or The infusion bottle is filled due to the large bore and nozzle cross sections in the adapter quickly with little Effort.

Each nozzle integrated in the mandrel has a jet direction, that deviates from the center line of the adapter by at least 30 °. This prevents the saline solution when injected directly into the second infusion bottle meets the lyophilisate. It is usually attached to the and / or sprayed inside the bottle. Depending on the infusion bottle position it flows along there or drips from there down. In this way it is prevented that the lyophilisate partially clumps.

For easier or ergonomic handling of the adapter the funnel sits on the handle element so that its Top edge of the handle element is a length away that about 2/3 of the middle, distant index finger width of one male adults according to DIN 33 402 Part 2. To the The patient stops, for example, by piercing the sealing plug the adapter with the infusion bottle positioned underneath in the area between the funnel and the handle element between the index and middle fingers, with the spine on the inside of the hand shows. With the thumb of the same hand on the ground of the infusion bottle, it pushes in a kind of Forceps move the infusion bottle and the adapter onto each other to. With this design, the patient is not forced to the adapter by placing your fingers on the sterile Connect the funnel to the infusion bottle.

The edge design also serves for easier handling of the grip element and / or the funnel. At least one of the Parts are flattened in the edge area, for example. This will make the adapter sterile after removing it Packing a roll away on a slightly inclined Level prevented.

The adapter is made, for example, by injection molding made of clear, transparent plastic. Preferably it consists of one piece. Depending on the purpose there may be a vent duct with or without a particle filter contain.

Furthermore, instead of the simple inner cone in the funnel base an inner cone with locking, e.g. a luer lock inner cone, be integrated.

Further details of the invention result from the exemplary embodiment described below and shown schematically.

Figure 1:
Adapter in a partially sectioned side view, a bottom view and a container on which the adapter is placed;
Figure 2:
Top view of the adapter;
Figure 3:
Front view of thorn, enlarged, with two cuts.

Figure 1 shows the adapter in the middle in a side view. The adapter is shown enlarged by a factor of two and cut on one side. It is suitable for a liquid with the aid of a syringe, for example a disposable syringe according to DIN 13098 part 1 with outer cone, without injection cannula from a closed injection bottle according to DIN ISO 8362 Take part 1. Such an injection bottle (1), see. FIG. 1, lower drawing, is closed with a stopper (2), by an aluminum crimp cap (3) on the Injection bottle (1) is held. The injection bottle shown (1) has a volume of approx. 4 ml.

The adapter has one in its middle area Handle plate (21) aligned vertically. centric a mandrel (11) is arranged below the handle plate (21). With it, the plug (2) when putting on the Push the adapter through the injection bottle (1). To the Mandrel (11) around, parallel to it, four cantilever arms (25) in Circle arranged, which protrude from the handle plate (21) down. The cantilever arms (25) facilitate as a centering aid one placing the adapter on the corresponding injection bottle (1) and secondly they reach for the completely push the lower edge of the crimp cap. On the handle plate (21) is a funnel-shaped connecting part (31) arranged after the insertion of the outer cone DIN 13090 part 1 of the disposable syringe facilitated and a tight Establishes connection between disposable syringe and adapter.

The connection part (31) below the handle plate (21) concentrically arranged mandrel (11) has one circular cross section, at least in the front area tapered towards a tip, see Figure 3. In the here Detail "Z" shown at the bottom right is the mandrel (11) the adapter center line by 90 ° compared to the illustration in Figure 1 shown rotated.

The mandrel (11) has a central bore (12) in the upper part. in the middle of the mandrel in two perpendicular to the adapter center line arranged nozzles (13) merges. The diameter the bore (12) corresponds approximately to the bore diameter from the outer cone of the standardized disposable syringe.

The opposing nozzles (13) have approximately one rectangular opening cross-section. Each nozzle (13) opens out into one aligned in the mandrel (11) parallel to the adapter center line Groove (14). Located immediately below each nozzle (13) a lip (15), the outer contour of which is in the nozzle area corresponds approximately to the contour of the bore (12) and thereby rises above the bottom of the groove. The lip (15) prevents i.a. on Blocking of the nozzles (13) lying above them during the piercing the plug, for example made of rubber (2).

To influence the jet direction of the nozzles (13), the Because of the hole (12) have different shapes. For example a blasting at approx. 45 ° to the adapter center line if desired, the bore (12) is provided with a bottom, which has the shape of a gable roof, with each roof side is facing a nozzle. The lower edges of the roof form the lower edges of the nozzle openings.

Each of the four cantilever arms arranged around the mandrel (11) (25) has a cross-section over its entire length that approximately corresponds to the shape of a circular ring section. The The inner diameter of the circular ring sections is slightly larger than the outside diameter of the crimp cap (3) of the injection bottle (1). Has the outer contour of the circular ring section approx. the length of 1/8 of the circumference. The not curved ones Side surfaces of the cantilever arms (25) form planes around the Half the cantilever width offset parallel to the center line of the adapter run. Approximately at half the height of each cantilever (25) a detent (26) is arranged on the inside thereof. each Latch (26) has a trapezoidal cross section and extends across the entire width of each cantilever (25). The nose flank oriented towards the grip plate (21) is inclined by approx. 30 ° to the horizontal. In the The direction of the nose is aligned with the Horizontal an angle of approx. 41 °. The Lugs (26) rise approx. 0.7 mm above the inner contour of the cantilever arms (25).

On the outer contour, each cantilever arm (25) has the handle plate in the upper one (21) oriented area a parallel to the adapter center line and stiffening rib aligned centrally to the cantilever width (27). It has a semicircular cross section. About the appropriate dimensioning of the cross section and the length of the individual stiffening rib (27) can affect the bending stiffness of each cantilever (25) become.

The handle plate carrying the mandrel (11) and the cantilever arms (25) (21) is a flat, substantially circular Plate. Missing in the areas between two cantilever arms (25) each have a circular section with, for example, 0.9 mm arc height to the full circle. The flats (22) prevent rolling of the adapter on one slightly against the horizontal inclined, inclined plane.

On the base plate (21) is concentric to the mandrel (11) Connection part (31) formed. It consists of a funnel (33), an inner cone element (32) and four stiffening ribs (34). The inner cone element (32) is directly with the Base plate (21) connected. It is the counterpart to the outer cone the disposable syringe to be coupled. By pushing in the outer cone of the disposable syringe into the inner cone element (32) creates a relatively rigid connection. It is liable the outer cone in the inner cone element (32) via frictional connection. The funnel (33) connects to the inner cone element (32) on. For example, it has an opening angle of 110 °. His maximum outer diameter corresponds to the base plate diameter. Between the funnel (33) and the base plate (21) are the four stiffening ribs along the inner cone element (32) (34) arranged. They are located in radial planes the adapter center line, cf. Figure 2. There they are in the Top view shown in dashed lines. The individual stiffening ribs (34) are in the middle above the cantilever arms (25) arranged. The depth of the stiffening ribs (34) is chosen, for example, so that the radius of one around the outer edges of the stiffening ribs (34) around the circumference centered between the outer radius of the inner cone element (32) and the maximum radius of the funnel (33).

LIST OF REFERENCE NUMBERS

1
Container, infusion bottle R2
2
Plug
3
Crimp cap, aluminum crimp cap
11
mandrel
12
drilling
13
jet
14
groove
15
lips
21
Handle element, handle plate
22
flats
25
Centering and gripping part, cantilever arms
26
Locking elements, locking lugs
27
stiffening ribs
31
connecting part
32
Inner cone element
33
funnel
34
stiffening ribs

Claims (5)

  1. Adaptor for withdrawing a liquid from a receptacle (1) sealed with a stopper or for filling such a receptacle (1) sealed by means of a stopper (2) fixed in place by a crimped-on cap (3), having at its forward end at least one partially hollow spike (11) provided with at least one nozzle (13), having at its rear end a connecting portion (31) comprising an internal cone, and having in the region located therebetween a flat gripping element (21) comprising a base plate, there being arranged on that gripping element (21), towards the forward end of the adaptor, a resilient engaging-around portion (25), the internal contour of which corresponds approximately to the external contour of the crimped-on cap (3) at least in some regions and which has locking elements (26), which engage behind the crimped-on cap (3) at least partly and are located spaced apart from the base plate by at least the height of the crimped-on cap (3), the forward edge of the engaging-around portion (25) projecting beyond the spike (11),
    characterised in that
    the locking elements (26) are located in the region behind the tip of the spike (11);
    a funnel (33) open towards the rear end is arranged on the connecting portion (31); and
    the forward edge of the engaging-around portion (25) extends beyond the locking element (26) and is so shaped as to centre the adaptor when it is being placed on the receptacle (1).
  2. Adaptor according to claim 1, characterised in that each nozzle (13) incorporated in the spike (11) has a jet direction that departs by at least 30° from the centre-line of the adaptor.
  3. Adaptor according to claim 1, characterised in that the upper edge of the funnel (33) is spaced apart from the gripping element (21) by 2/3 of the average distal index finger width of a male adult according to DIN 33 402 Part 2.
  4. Adaptor according to claim 1, characterised in that the external contour of the gripping element (21) and/or of the funnel (33) is not round.
  5. Adaptor according to claim 1, characterised in that it consists of one piece.
EP19960945696 1995-10-20 1996-10-18 Adapter for extracting a liquid from a container closed with a stopper Expired - Lifetime EP0957883B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE19540476 1995-10-20
DE19540476 1995-10-20
PCT/DE1996/002027 WO1997015267A2 (en) 1995-10-20 1996-10-18 Adapter for extracting a liquid from a container closed with a stopper

Publications (2)

Publication Number Publication Date
EP0957883A2 EP0957883A2 (en) 1999-11-24
EP0957883B1 true EP0957883B1 (en) 2003-03-05

Family

ID=7776218

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19960945696 Expired - Lifetime EP0957883B1 (en) 1995-10-20 1996-10-18 Adapter for extracting a liquid from a container closed with a stopper

Country Status (8)

Country Link
US (1) US6039093A (en)
EP (1) EP0957883B1 (en)
AT (1) AT233530T (en)
AU (1) AU1765097A (en)
DK (1) DK0957883T3 (en)
ES (1) ES2192236T3 (en)
PT (1) PT957883E (en)
WO (1) WO1997015267A2 (en)

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US6681946B1 (en) 1998-02-26 2004-01-27 Becton, Dickinson And Company Resealable medical transfer set
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
US6681475B2 (en) 1998-04-20 2004-01-27 Becton Dickinson And Company Method of sealing a medical container with a plastic closure
US6382442B1 (en) 1998-04-20 2002-05-07 Becton Dickinson And Company Plastic closure for vials and other medical containers
AR042539A1 (en) * 2003-12-18 2005-06-22 Jose Santiago Rolla Supply unit for injecting manually or automatically
AU2004316287B2 (en) * 2004-02-20 2007-11-15 Point Guard Medical, Incorporated Needle guide
US8123736B2 (en) * 2009-02-10 2012-02-28 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
US8162914B2 (en) * 2009-02-10 2012-04-24 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
IL201323D0 (en) 2009-10-01 2010-05-31 Medimop Medical Projects Ltd Fluid transfer device for assembling a vial with pre-attached female connector
IL202069D0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Fluid transfer device with sealing arrangement
IL202070D0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Inline liquid drug medical device
BR112012021134A2 (en) 2010-02-24 2016-05-17 Medimop Medical Projects Ltd fluid transfer assembly with ventilation arrangement
US8753325B2 (en) 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter
IL209290D0 (en) 2010-11-14 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device having rotary flow control member
IL212420D0 (en) 2011-04-17 2011-06-30 Medimop Medical Projects Ltd Liquid drug transfer assembly
IL215699D0 (en) 2011-10-11 2011-12-29 Medimop Medical Projects Ltd Liquid drug reconstitution assemblage for use with iv bag and drug vial
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
USD737436S1 (en) 2012-02-13 2015-08-25 Medimop Medical Projects Ltd. Liquid drug reconstitution assembly
IL219065D0 (en) 2012-04-05 2012-07-31 Medimop Medical Projects Ltd Fluid transfer device with manual operated cartridge release arrangement
IL221634D0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Universal drug vial adapter
IL221635D0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Drug vial mixing and transfer device for use with iv bag and drug vial
DK2872100T3 (en) 2012-09-13 2017-07-10 Medimop Medical Projects Ltd Telescopic female adapter for drug ampoule
USD734868S1 (en) 2012-11-27 2015-07-21 Medimop Medical Projects Ltd. Drug vial adapter with downwardly depending stopper
IL225734D0 (en) 2013-04-14 2013-09-30 Medimop Medical Projects Ltd Ready-to-use drug vial assemblages including drug vial and drug vial closure having fluid transfer member, and drug vial closure therefor
CN105228676B (en) 2013-05-10 2018-01-05 麦迪麦珀医疗工程有限公司 Include the medical treatment device of the vial adapter with inline dry kit
USD767124S1 (en) 2013-08-07 2016-09-20 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
USD765837S1 (en) 2013-08-07 2016-09-06 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
US9919826B2 (en) * 2013-09-23 2018-03-20 Becton Dickinson and Company Ltd. Piercing member for container access device
USD757933S1 (en) 2014-09-11 2016-05-31 Medimop Medical Projects Ltd. Dual vial adapter assemblage
EP3217944B1 (en) 2015-01-05 2019-04-10 West Pharma. Services IL, Ltd Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
JP6367512B1 (en) 2015-07-16 2018-08-01 ウエスト・ファーマ.サービシーズ・イスラエル,リミテッド Solution transfer device for securely snap-fitting into injection vials
USD801522S1 (en) 2015-11-09 2017-10-31 Medimop Medical Projects Ltd. Fluid transfer assembly
WO2017090042A1 (en) 2015-11-25 2017-06-01 Medimop Medical Projects Ltd Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
USD832430S1 (en) 2016-11-15 2018-10-30 West Pharma. Services IL, Ltd. Dual vial adapter assemblage

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IE60235B1 (en) * 1986-09-18 1994-06-15 Kabi Pharmacia Ab "Connector and disposable assembly utilising said connector"
GB9103291D0 (en) * 1991-02-15 1991-04-03 Waverley Pharma Ltd Transfer adaptor
GB9211912D0 (en) * 1992-06-04 1992-07-15 Drg Flexpak Ltd Vial connector system
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EP0692235A1 (en) * 1994-07-14 1996-01-17 International Medication Systems (U.K.) Ltd. Mixing & dispensing apparatus
US5526853A (en) * 1994-08-17 1996-06-18 Mcgaw, Inc. Pressure-activated medication transfer system

Also Published As

Publication number Publication date
US6039093A (en) 2000-03-21
WO1997015267A2 (en) 1997-05-01
DK957883T3 (en)
ES2192236T3 (en) 2003-10-01
PT957883E (en) 2003-07-31
WO1997015267A3 (en) 1997-07-17
AT233530T (en) 2003-03-15
DK0957883T3 (en) 2003-06-30
EP0957883A2 (en) 1999-11-24
AU1765097A (en) 1997-05-15

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