EP0949946A4 - Behandeln von biologischen flüssigkeiten - Google Patents

Behandeln von biologischen flüssigkeiten

Info

Publication number
EP0949946A4
EP0949946A4 EP97954595A EP97954595A EP0949946A4 EP 0949946 A4 EP0949946 A4 EP 0949946A4 EP 97954595 A EP97954595 A EP 97954595A EP 97954595 A EP97954595 A EP 97954595A EP 0949946 A4 EP0949946 A4 EP 0949946A4
Authority
EP
European Patent Office
Prior art keywords
biological fluid
obtaining
leukocyte
container
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97954595A
Other languages
English (en)
French (fr)
Other versions
EP0949946A1 (de
Inventor
Judy Angelbeck
Barry Wenz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pall Corp
Original Assignee
Pall Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pall Corp filed Critical Pall Corp
Publication of EP0949946A1 publication Critical patent/EP0949946A1/de
Publication of EP0949946A4 publication Critical patent/EP0949946A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0439—White blood cells; Leucocytes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues

Definitions

  • stored and/or non-stored components typically include undesirable material such as bacteria and/or leukocytes.
  • Bacteria can contaminate the blood or blood component during blood collection and/or storage.
  • One source of bacterial contamination may be the blood donor's skin, which may contain one or more varieties of bacteria, e.g., gram positive bacteria such as Staphylococcus epidermidis. and S ⁇ aureus, and/or gram negative bacteria. Since swabbing the donor's skin (e.g. , with alcohol) prior to venipuncture may be inadequate to assure sterility, the bacteria may pass into the blood collection container, and the bacteria may reproduce while the blood or blood component is stored. Moreover, since some phlebotomy needles may cut a disc of skin when the phlebotomy needle is inserted into the donor, the bacteria-containing skin plug can pass with the blood into the blood collection container, and the bacteria can reproduce during storage.
  • Figure 4B illustrates another embodiment of a biological fluid pooling system that can be used in accordance with the invention.
  • the illustrated system includes a plurality of containers 12, each suitable for holding a biological fluid such as buffy coat, in fluid communication via conduits 160 with a first receiving container 118a for pooled buffy coat.
  • the illustrated system in Figure 4B also includes a filter assembly 26, such as a leukocyte depletion assembly, interposed between the first receiving container 118a and a second receiving container 118a.
  • the system also includes an additional container 20, e.g., for holding an additive or wash solution.
  • pooled biological fluid is then recovered in the receiving or transfer container 118a and, in accordance with the invention, the introduction of air or gas into the receiving container can be minimized, so the biological fluid is recovered without collecting excess air.
  • gas may be introduced behind the biological fluid retained in the system. Using the illustrative system illustrated in Figure 3 for reference, the gas that was initially introduced into the containers 18a through either the gas inlet 80 or the gas outlet 82 will follow the biological fluid as it flows through the conduits. This increases the recovery of the biological fluid, since the gas following the biological fluid "chases" the fluid from the conduits.
EP97954595A 1996-12-24 1997-12-19 Behandeln von biologischen flüssigkeiten Withdrawn EP0949946A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3414596P 1996-12-24 1996-12-24
US34145P 1996-12-24
PCT/US1997/023558 WO1998028057A1 (en) 1996-12-24 1997-12-19 Biological fluid processing

Publications (2)

Publication Number Publication Date
EP0949946A1 EP0949946A1 (de) 1999-10-20
EP0949946A4 true EP0949946A4 (de) 2001-02-14

Family

ID=21874592

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97954595A Withdrawn EP0949946A4 (de) 1996-12-24 1997-12-19 Behandeln von biologischen flüssigkeiten

Country Status (5)

Country Link
EP (1) EP0949946A4 (de)
JP (1) JP2001507353A (de)
AU (1) AU736156B2 (de)
CA (1) CA2271440A1 (de)
WO (1) WO1998028057A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592613B1 (en) 1998-01-16 2003-07-15 Terumo Kabushiki Kaisha Blood collecting apparatus and blood collecting method using blood collecting apparatus
US6387086B2 (en) 1999-07-29 2002-05-14 Baxter International Inc. Blood processing set including an integrated blood sampling system
JP2003514218A (ja) * 1999-10-29 2003-04-15 パル・コーポレーション 生物学的流体処理
JP2002173433A (ja) 2000-12-04 2002-06-21 Terumo Corp 白血球除去血液製剤の調製方法および血液セット
US7264608B2 (en) * 2001-12-05 2007-09-04 Fenwal, Inc. Manual processing systems and methods for providing blood components conditioned for pathogen inactivation
US20040009542A1 (en) * 2002-05-03 2004-01-15 Gambro, Inc. Apparatus and method for detecting bacteria in blood products
ITRM20030467A1 (it) * 2003-10-10 2005-04-11 Advance Holdings Ltd Contenitore monouso per la centrifugazione ed il trattamento di un materiale biologico fluido.
BRPI1007666B8 (pt) * 2009-05-14 2021-05-25 Biotechnology Inst I Mas D Sl método para preparar um composto a partir do sangue e dispositivo de extração
DE102012022826B4 (de) * 2012-11-22 2022-10-13 Hubert Wöllenstein Verfahren zur Herstellung eines gepoolten Thrombozytenkonzentrats
US9796166B2 (en) 2014-03-24 2017-10-24 Fenwal, Inc. Flexible biological fluid filters
US9968738B2 (en) 2014-03-24 2018-05-15 Fenwal, Inc. Biological fluid filters with molded frame and methods for making such filters
US9782707B2 (en) 2014-03-24 2017-10-10 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US10159778B2 (en) 2014-03-24 2018-12-25 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US10376627B2 (en) 2014-03-24 2019-08-13 Fenwal, Inc. Flexible biological fluid filters
US11135343B2 (en) 2016-12-01 2021-10-05 Fenwal, Inc. Blood component pooling device, system and method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2058577A5 (de) * 1969-09-17 1971-05-28 Medicoplast Labor
US4280497A (en) * 1979-10-09 1981-07-28 Cutter Laboratories, Inc. Container for platelet storage
US4670013A (en) * 1982-12-27 1987-06-02 Miles Laboratories, Inc. Container for blood and blood components
WO1989009025A1 (en) * 1988-03-31 1989-10-05 Maria Hansby Blood collecting unit and its use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0349188B1 (de) * 1988-06-23 1992-09-02 ASAHI MEDICAL Co., Ltd. Verfahren zur Trennung von Blut in Blutkomponenten und Einheit zur Trennung von Blutkomponenten
US5100564A (en) * 1990-11-06 1992-03-31 Pall Corporation Blood collection and processing system
CA2072378C (en) * 1991-11-21 2000-12-26 Vlado Ivan Matkovich System for processing separate containers of biological fluid
US5549834A (en) * 1991-12-23 1996-08-27 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
CA2083075A1 (en) * 1992-06-10 1993-12-11 Vlado I. Matkovich System for treating transition zone material

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2058577A5 (de) * 1969-09-17 1971-05-28 Medicoplast Labor
US4280497A (en) * 1979-10-09 1981-07-28 Cutter Laboratories, Inc. Container for platelet storage
US4670013A (en) * 1982-12-27 1987-06-02 Miles Laboratories, Inc. Container for blood and blood components
WO1989009025A1 (en) * 1988-03-31 1989-10-05 Maria Hansby Blood collecting unit and its use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9828057A1 *

Also Published As

Publication number Publication date
WO1998028057A1 (en) 1998-07-02
JP2001507353A (ja) 2001-06-05
AU736156B2 (en) 2001-07-26
CA2271440A1 (en) 1998-07-02
AU5900898A (en) 1998-07-17
EP0949946A1 (de) 1999-10-20

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