EP0938313A4 - Verfahren und zusammenstellungen zur behandlung von urininkontinenz durch enantomerisch angereichertes (s)-clidinum - Google Patents
Verfahren und zusammenstellungen zur behandlung von urininkontinenz durch enantomerisch angereichertes (s)-clidinumInfo
- Publication number
- EP0938313A4 EP0938313A4 EP97932350A EP97932350A EP0938313A4 EP 0938313 A4 EP0938313 A4 EP 0938313A4 EP 97932350 A EP97932350 A EP 97932350A EP 97932350 A EP97932350 A EP 97932350A EP 0938313 A4 EP0938313 A4 EP 0938313A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- clidinium
- compositions
- methods
- urinary incontinence
- enantiomerically enriched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2092596P | 1996-07-01 | 1996-07-01 | |
US20925P | 1996-07-01 | ||
PCT/US1997/011259 WO1998000139A1 (en) | 1996-07-01 | 1997-06-27 | Methods and compositions for treating urinary incontinence using enantiomerically enriched (s)-clidinium |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0938313A1 EP0938313A1 (de) | 1999-09-01 |
EP0938313A4 true EP0938313A4 (de) | 2000-02-23 |
Family
ID=21801321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97932350A Withdrawn EP0938313A4 (de) | 1996-07-01 | 1997-06-27 | Verfahren und zusammenstellungen zur behandlung von urininkontinenz durch enantomerisch angereichertes (s)-clidinum |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0938313A4 (de) |
WO (1) | WO1998000139A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060210625A1 (en) * | 2003-11-04 | 2006-09-21 | Shire Laboratories, Inc. | Sustained release of positively charged pharmacologically active molecules from a matrix containing polymers with polarized oxygen atoms |
CA2536401C (en) * | 2003-11-04 | 2011-08-30 | Shire Laboratories Inc. | Compositions of quaternary ammonium compounds containing bioavailability enhancers |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1219606A (en) * | 1968-07-15 | 1971-01-20 | Rech S Et D Applic Scient Soge | Quinuclidinol derivatives and preparation thereof |
US4644003A (en) * | 1985-04-03 | 1987-02-17 | Research Corporation | 3-quinuclidinol esters, useful as antagonists of muscarinic acetylcholine receptors |
US5340826A (en) * | 1993-02-04 | 1994-08-23 | Pfizer Inc. | Pharmaceutical agents for treatment of urinary incontinence |
-
1997
- 1997-06-27 WO PCT/US1997/011259 patent/WO1998000139A1/en not_active Application Discontinuation
- 1997-06-27 EP EP97932350A patent/EP0938313A4/de not_active Withdrawn
Non-Patent Citations (7)
Title |
---|
HAURI D.: "[Incontinence of urine: Possibilities for pharmacotherapy].", MEDIZINISCHE MONATSSCHRIFT FUR PHARMAZEUTEN, (1984) 7/8 (233-239). CODEN: MMPHDB, XP000863460 * |
KOPPENHOEFER B. ET AL: "Separation of enantiomers of drugs by capillary electrophoresis I..gamma.-Cyclodextrin as chiral solvating agent.", JOURNAL OF CHROMATOGRAPHY A, (1995) 717/1-2 (181-190)., XP000605057 * |
KOPPENHOEFER, BERNHARD ET AL: "Separation of enantiomers of drugs by capillary electrophoresis Part 4: hydroxypropyl-gamma-cyclodextrin as chiral solvating agent", ELECTROPHORESIS (1997), 18(6), 924-930, XP000863400 * |
LIN B C (REPRINT) ET AL: "SEPARATION OF DRUG ENANTIOMERS BY CAPILLARY ELECTROPHORESIS ALPHA-CYCLODEXTRIN AS CHIRAL SOLVATING AGENT", CHROMATOGRAPHIA, (JAN 1996) VOL. 42, NO. 1-2, PP. 106-110. ISSN: 0009-5893., vol. 42, no. 1/2, 1996, DALIAN INST CHEM PHYS, ZHONG SHAN RD 161, DALIAN 116012, PEOPLES R CHINA (Reprint);CHINA PHARMACEUT UNIV, NANJING 250009, PEOPLES R CHINA; UNIV TUBINGEN, INST ORGAN CHEM, D-72076 TUBINGEN, GERMANY, pages 106 - 110, XP000863359 * |
LIN, BINGCHENG ET AL: "Investigation of 123 chiral drugs by cyclodextrin-modified capillary electrophoresis", LC-GC (1997), 15(1), 40, 44-46, XP000863469 * |
See also references of WO9800139A1 * |
YURDAKOK M ET AL: "Treatment of enuresis: a study with imipramine, amitriptyline, chlordiazepoxide- clidinium and piracetam.", TURKISH JOURNAL OF PEDIATRICS, (1986 JUL-SEP) 28 (3) 171-5., XP000863478 * |
Also Published As
Publication number | Publication date |
---|---|
EP0938313A1 (de) | 1999-09-01 |
WO1998000139A1 (en) | 1998-01-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19990120 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20000111 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20030103 |