EP0934250A4 - Verfahren zum herstellen pharmazeutischer verbindungen - Google Patents

Verfahren zum herstellen pharmazeutischer verbindungen

Info

Publication number
EP0934250A4
EP0934250A4 EP97941436A EP97941436A EP0934250A4 EP 0934250 A4 EP0934250 A4 EP 0934250A4 EP 97941436 A EP97941436 A EP 97941436A EP 97941436 A EP97941436 A EP 97941436A EP 0934250 A4 EP0934250 A4 EP 0934250A4
Authority
EP
European Patent Office
Prior art keywords
pharmaceutical compounds
prepare pharmaceutical
compounds
prepare
cryptophycin compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97941436A
Other languages
English (en)
French (fr)
Other versions
EP0934250A2 (de
Inventor
Andrew H Fray
Michael J Martinelli
Eric D Moher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hawaii
Wayne State University
Eli Lilly and Co
Original Assignee
University of Hawaii
Wayne State University
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hawaii, Wayne State University, Eli Lilly and Co filed Critical University of Hawaii
Publication of EP0934250A2 publication Critical patent/EP0934250A2/de
Publication of EP0934250A4 publication Critical patent/EP0934250A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP97941436A 1996-09-06 1997-09-05 Verfahren zum herstellen pharmazeutischer verbindungen Withdrawn EP0934250A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2543796P 1996-09-06 1996-09-06
US25437P 1996-09-06
PCT/US1997/015668 WO1998009601A2 (en) 1996-09-06 1997-09-05 Process to prepare pharmaceutical compounds

Publications (2)

Publication Number Publication Date
EP0934250A2 EP0934250A2 (de) 1999-08-11
EP0934250A4 true EP0934250A4 (de) 2004-08-11

Family

ID=21826065

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97941436A Withdrawn EP0934250A4 (de) 1996-09-06 1997-09-05 Verfahren zum herstellen pharmazeutischer verbindungen

Country Status (9)

Country Link
EP (1) EP0934250A4 (de)
JP (1) JP2001500128A (de)
KR (1) KR20010029475A (de)
AU (1) AU4334397A (de)
BR (1) BR9711695A (de)
CA (1) CA2264527A1 (de)
HU (1) HUP0000212A3 (de)
IL (2) IL128643A0 (de)
WO (1) WO1998009601A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19911088A1 (de) * 1999-03-12 2000-09-28 Fraunhofer Ges Forschung Manuell geführtes Montagesystem
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995017093A1 (en) * 1993-12-21 1995-06-29 University Of Hawaii New cryptophycins
WO1996040184A1 (en) * 1995-03-07 1996-12-19 University Of Hawaii New cryptophycins from synthesis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952298A (en) * 1993-12-21 1999-09-14 The University Of Hawaii Cryptophycins
WO1997008334A1 (en) * 1995-08-30 1997-03-06 University Of Hawaii Cryptophycins from aberrant biosynthesis
DE69626544T2 (de) * 1995-12-22 2004-01-15 Lilly Co Eli Arzneistoffe
AU2058197A (en) * 1996-02-27 1997-09-16 Eli Lilly And Company Pharmaceutical compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995017093A1 (en) * 1993-12-21 1995-06-29 University Of Hawaii New cryptophycins
WO1996040184A1 (en) * 1995-03-07 1996-12-19 University Of Hawaii New cryptophycins from synthesis

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BARROW R A ET AL: "TOTAL SYNTHESIS OF CRYPTOPHYCINS. REVISION OF THE STRUCTURES OF CRYPTOPHYCINS A AND C", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 117, no. 9, 8 March 1995 (1995-03-08), pages 2479 - 2490, XP002066281, ISSN: 0002-7863 *
ISHIHARA K. ET AL.: "Antimony-templated macrolactamization of tetraamino esters.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 118, no. 6, 14 February 1996 (1996-02-14), USAMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., pages 1569 - 1570, XP002283973 *
MENGER F. M. ET AL.: "Anion-catalyzed ester aminolyses in a hydrocarbon solvent", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 95, no. 15, 1973, USAMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., pages 4931 - 4934, XP002283974 *
RONY P. R.: "Polyfunctional catalysis. III. Tautomeric catalysis.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 91, no. 22, 1969, USAMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., pages 6090 - 6096, XP002283975 *
WASSERMAN H.H. ET AL.: "Total synthesis of (+-)-Chaenorhine", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 105, no. 6, 1983, USAMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., pages 1697 - 1698, XP002283972 *

Also Published As

Publication number Publication date
AU4334397A (en) 1998-03-26
WO1998009601A3 (en) 1998-04-23
CA2264527A1 (en) 1998-03-12
WO1998009601A2 (en) 1998-03-12
JP2001500128A (ja) 2001-01-09
IL128643A0 (en) 2000-01-31
KR20010029475A (ko) 2001-04-06
HUP0000212A3 (en) 2001-12-28
BR9711695A (pt) 2000-03-08
IL128643A (en) 2006-04-10
HUP0000212A2 (en) 2000-07-28
EP0934250A2 (de) 1999-08-11

Similar Documents

Publication Publication Date Title
ZA968957B (en) Process for the preparation of dihaloazolopyrimidines.
HUP0003305A3 (en) Hiv protease inhibiting tetrahydro-pyrimid-2-on derivative, pharmaceutical compositions containing it and process for producing the compound
ZA9710322B (en) Process for the preparation of benzyl-ethers.
AU4699697A (en) A process for the preparation of (-)-3,4-trans-diarylchromans
EG22337A (en) Process for preparing novel pharmaceutical compounds
AU4838996A (en) Process for tetraazacycloalkane preparation
AU3092297A (en) Process for preparing bitument compositions
EP0673920A3 (de) Verfahren zur Herstellung von Ethanolaminen.
AU1448097A (en) Substances extracted from dictyotales, a process for obtaining them and compositions comprising them
ZA988711B (en) New tetracycles, process for their production and pharmaceutical preparations containing these compounds.
AU7407396A (en) A process for the preparation of pentaerythritol
HU9602763D0 (en) Novel isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
IL131205A0 (en) Process for preparing pharmaceutical compounds
AU3255997A (en) Process for preparing 1,3-alkanediols
AU8127298A (en) Isoxazole compounds, process for the preparation thereof, and insecticides and acaricides
HUP0003452A3 (en) Process for the preparation of 1-aryl-3-cyclopropyl-1,3-propanediones
WO1998009601A3 (en) Process to prepare pharmaceutical compounds
ZA982255B (en) Process for the preparation of arylmalonates.
ZA9711098B (en) Substituted [3H]-benzoxazoles-2-thione and [3H]-benzothiazole-2-thione compounds, a process for their preparation and pharmaceutical compositions containing them.
AU4233997A (en) Process for preparing pharmaceutical compounds
AU4958397A (en) Process for making benzisothiazolin-3-ones
ZA982449B (en) Process for preparing 1-Alkyl-4-(2-chloro-3-alkoxy-4-alkylsulfonylbenzoyl)-5-hydroxypyrazole and related compounds.
AU3783097A (en) Process for the preparation of hexanitrohexaazaisowurtzitanes
AU3953297A (en) Process for preparing paclitaxel
AU7705396A (en) Quinoxaline compounds, pharmaceutical preparations containing them and a process for the preparation thereof

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19990303

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

AX Request for extension of the european patent

Free format text: AL PAYMENT 19990303;LT PAYMENT 19990303;LV PAYMENT 19990303;RO PAYMENT 19990303;SI PAYMENT 19990303

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

A4 Supplementary search report drawn up and despatched

Effective date: 20040629

18D Application deemed to be withdrawn

Effective date: 20040702