EP0906117A1 - Procede de traitement ou de prevention des lesions lors d'une reperfusion au cours d'une ischemie - Google Patents

Procede de traitement ou de prevention des lesions lors d'une reperfusion au cours d'une ischemie

Info

Publication number
EP0906117A1
EP0906117A1 EP97921343A EP97921343A EP0906117A1 EP 0906117 A1 EP0906117 A1 EP 0906117A1 EP 97921343 A EP97921343 A EP 97921343A EP 97921343 A EP97921343 A EP 97921343A EP 0906117 A1 EP0906117 A1 EP 0906117A1
Authority
EP
European Patent Office
Prior art keywords
ischemia
reperfusion injury
injury
repair
reperfusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97921343A
Other languages
German (de)
English (en)
Inventor
James M. Seeger
Timothy R. S. Harward
Satwant K. Narula
Lyle L. Moldawer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of EP0906117A1 publication Critical patent/EP0906117A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2066—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pretreatment Of Seeds And Plants (AREA)

Abstract

L'invention concerne un procédé de fabrication d'une composition pharmaceutique destinée au traitement des lésions lors d'une reperfusion au cours d'une ischémie, ce procédé consistant à mélanger un excipient acceptable sur le plan pharmacologique et une quantité suffisante d'interleukine-10.
EP97921343A 1996-05-02 1997-05-01 Procede de traitement ou de prevention des lesions lors d'une reperfusion au cours d'une ischemie Withdrawn EP0906117A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64185996A 1996-05-02 1996-05-02
US641859 1996-05-02
PCT/US1997/006809 WO1997040849A1 (fr) 1996-05-02 1997-05-01 Procede de traitement ou de prevention des lesions lors d'une reperfusion au cours d'une ischemie

Publications (1)

Publication Number Publication Date
EP0906117A1 true EP0906117A1 (fr) 1999-04-07

Family

ID=24574163

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97921343A Withdrawn EP0906117A1 (fr) 1996-05-02 1997-05-01 Procede de traitement ou de prevention des lesions lors d'une reperfusion au cours d'une ischemie

Country Status (9)

Country Link
EP (1) EP0906117A1 (fr)
JP (1) JP2000509073A (fr)
KR (1) KR20000065178A (fr)
AU (1) AU721943B2 (fr)
BR (1) BR9709752A (fr)
CA (1) CA2253313A1 (fr)
IL (1) IL126657A0 (fr)
NZ (1) NZ332412A (fr)
WO (1) WO1997040849A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6113629A (en) * 1998-05-01 2000-09-05 Micrus Corporation Hydrogel for the therapeutic treatment of aneurysms
AU2158000A (en) 1998-12-22 2000-07-12 Schering Corporation Treatment of hepatitis c virus infections with interleukin-10
US7108982B1 (en) 1999-02-19 2006-09-19 University Of Iowa Research Foundation Diagnostics and the therapeutics for macular degeneration
AU3704900A (en) * 1999-02-19 2001-02-05 University Of Iowa Research Foundation, The Diagnostics and therapeutics for macular degeneration
EP1620097A4 (fr) * 2003-04-25 2008-03-05 Mitos Inc Pretraitement preventif par antioxydants
JP6999664B2 (ja) 2016-10-31 2022-01-18 サムスン ライフ パブリック ウェルフェア ファウンデーション 胆汁酸を含む虚血性再灌流損傷の予防または治療用薬学的組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP690A (en) * 1994-07-05 1998-10-16 Steeno Res Group A/S Immunomodulators based on a polypeptide other than human interleukin 10.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9740849A1 *

Also Published As

Publication number Publication date
WO1997040849A1 (fr) 1997-11-06
CA2253313A1 (fr) 1997-11-06
JP2000509073A (ja) 2000-07-18
NZ332412A (en) 2000-05-26
AU2740597A (en) 1997-11-19
AU721943B2 (en) 2000-07-20
IL126657A0 (en) 1999-08-17
KR20000065178A (ko) 2000-11-06
BR9709752A (pt) 1999-08-10

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