EP0904847B1 - Container with sealed insert and pump for breaking the seal - Google Patents
Container with sealed insert and pump for breaking the seal Download PDFInfo
- Publication number
- EP0904847B1 EP0904847B1 EP98104631A EP98104631A EP0904847B1 EP 0904847 B1 EP0904847 B1 EP 0904847B1 EP 98104631 A EP98104631 A EP 98104631A EP 98104631 A EP98104631 A EP 98104631A EP 0904847 B1 EP0904847 B1 EP 0904847B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- container
- pump device
- insert
- base
- wall
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/0005—Components or details
- B05B11/0037—Containers
- B05B11/0038—Inner container disposed in an outer shell or outer casing
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1043—Sealing or attachment arrangements between pump and container
- B05B11/1046—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container
- B05B11/1047—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container the pump being preassembled as an independent unit before being mounted on the container
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1081—Arrangements for pumping several liquids or other fluent materials from several containers, e.g. for mixing them at the moment of pumping
Definitions
- the invention relates to a container with a pump device for dispensing a liquid container content, such as a liquid drug.
- the container preferably has the shape of a vial with a bottle neck on which a spray pump or vacuum pump sits by depressing it of the upper pump part in the direction of the bottle neck predetermined amount of the liquid container contents in a chamber of the pump and then - with the next pump stroke - off fine channels of the upper pump part ejects, the liquid is atomized finely at an outlet nozzle.
- the liquid can also be dispensed drop by drop.
- Pumps are used, for example, to spray a liquid drug widespread in the nose.
- the invention preferably relates to those containers which are produced by the coextrusion blow molding process are made and from a rigid Outer container and consist of a soft inner bag, the Materials do not weld together.
- the preferred container is by squeezing the tubular preform sealed in the blow mold Bottom seam of the inner bag in an outwardly protruding Bottom web of the outer container is clamped, the outer web is also closed by means of a weld seam, which itself has formed in that the weld seam of the inner bag due to a jamming effect in the bottom seam of the outer container forming section withdrawn from the separation point Has.
- the wall of the outer container contains pressure equalization openings, for example through unwelded shoulder seams of the outer container or can be formed in that a Chip of the outer container cut flat on a convex section is, when the knife hits the Inner bag of the latter not damaged, but inside is pushed away. With the gradual release of the liquid The inner bag is increasingly contracting inside the container, whereby for pressure equalization according to ambient air through the Pressure equalization openings in the space between the outer container and the inner bag enters.
- the invention is not based on the use of such Container limited, and the container does not have to necessarily have a bottle shape with a bottle neck.
- the container according to the invention is also preferred for receiving of a liquid drug is provided and will follow described using such an example, although emphasized is that he will also take up and dispense another liquid is suitable if it consists of two substances, namely one solvent in the container and one in a second chamber of the container, initially kept separately, preferably in the solid state active ingredient is miscible.
- Some active pharmaceutical ingredients such as hormones are not long-term stable if they are dissolved in a liquid, which is especially the case when there are no preservatives can be added. To remedy this create, it is known to freeze such active ingredients in Store form and in a solvent before use enter with the active ingredient in the dissolved state a liquid Drugs forms, for example, by means of a Pipette can be administered.
- the present invention has for its object a container with a Specify the pump device that is used to receive and dispense a liquid an active ingredient that is not stable in the long term.
- the opening of the container preferably in the neck of the container, if there is one, essentially one tubular insert is arranged, which abuts the edge of the opening and has a bottom which is closed in a first state of the arrangement and before the first dispensing of the liquid container content by the action of a Force is opened.
- the front end portion of the preferably used as an airless pump engages, the peripheral wall of this front end portion or Suction section abuts the wall of the insert, and being the peripheral wall upon application of a corresponding force in the axial direction of the container can be moved relative to the insert.
- the in the closed state of the floor of one in the rest of the interior of the Container second substance is separated. If the bottom of the But opened by pushing the pump device forward or is torn open, the one in use Substance out of use and can with the substance be mixed in the container.
- This is in use preferably a freeze-dried active ingredient of a medicament first of all a solvent in the container, e.g. sterile water, isolated and after opening the bottom with mixed this liquid.
- a solvent in the container e.g. sterile water
- the essentially tubular insert has expediently a cylindrical shape, even if the bottle neck of the container and the front housing section of the pump device has a corresponding one Cylindrical shape - but with a larger or smaller one Diameter- has.
- the pump device extends over the front end region projecting tubular projection with the ball valve has, which is aligned with the circumferential groove of the bottom and on its free end is cut away obliquely, so that the projection when feeding the pump device into the container only with the tip of the projection into the groove occurs and the seam tears open with a high pressing force, whereby an increasing circumferential area the weakened seam with persistent Feed further tears open, so that finally the bottom in the position of use folds down and the content of the insert is fully released.
- the protrusion is preferred formed by the peripheral wall of the front suction area the pump device beyond the valve area is extended.
- the insert expediently lies on a ring shoulder the top of the container or the top edge of the container neck if there is one.
- an additional peripheral wall is arranged on the container, partially overlapped by a housing part of the pump device that is axially displaceable.
- the additional peripheral wall is expediently part of an outer cap that comprises at least the lower region of the container. It can the outer cap also extends to the top of the container.
- the outer cap on its upper Edge of a thickening with an outwardly projecting ring shoulder has, while the housing part of the pump device a thickening at the bottom with an inward protrusion Has ring shoulder.
- the thickening of the outer cap is accordingly facing the inner wall of the housing part while thickening of the housing part faces the outer wall of the outer cap. in the the two ring shoulders are in abutting condition the pump device is in the retracted starting position, in which the bottom of the insert is closed and the one inside Substance separated from the rest of the interior of the container is.
- both ring shoulders have bevels on the outside, which when feeding the housing part in the direction of Outer cap hit each other, creating the area of thickening of the housing part of the pump is expanded radially, while the housing part with its thickening over the thickening the outer cap slides. That way, these two can Part can be assembled easily.
- either the thickening of the Outer cap or the thickening of the housing part a small has radial excess, such that this thickening with a bias on the associated wall of the other Partial.
- this other wall is at an axial distance from the thickening formed a circumferential groove into which the The thickening engages with the radial oversize.
- This groove defines the position of the pump device in which the bottom of the Is torn open and unfolded and in which the Arrangement is in the state in which the container contents can be applied by the pump device.
- the pump device two axial positions of the pump device limited relative to the container, namely the withdrawn Initial situation due to the application of the ring shoulders to each other and the ready-to-use inserted into the container Location in which a thickening in the associated groove locks.
- the container sits in an outer cap that extends to the top of the container neck can be enough.
- the outer cap is at its upper edge area provided with a thread that is preferably on the Outside of the outer cap. With this thread is a Internal thread of a housing part of the pump device engages.
- the pump device By turning the housing part, the pump device is also pushed their suction section into the container until one Ring shoulder of another housing part of the pump device runs onto the container, causing the use position of the Pump device is defined.
- the front end portion of the pump means the bottom of the insert torn open and opened so that the active ingredient in the Container can enter.
- This screwing process makes the pump device continuous and smoothly pushed into the container with its suction section, tilting the suction section in the insert is reliably prevented.
- the one required to tear open the floor Force can also be achieved by screwing less skillful people can be easily applied.
- thread Sawtooth thread is used.
- the thread sections are preferably so short that in the advanced end position Thread of the housing part beyond the thread of the outer cap is screwed so that the housing part of the pump device can no longer be screwed back. Through this self-locking the thread, which also causes other measures can be reliably prevented that the pump device is moved out of its position of use.
- the figures show a bottle-shaped container 1 with a Neck 2, in which an insert 3 is arranged, with one after externally facing ring shoulder 4 on the upper edge of the bottle neck 2 rests.
- the insert 3 has a circular cylindrical shape and lies close to the inner wall of the container neck 2.
- the insert 3 has a bottom 5, which is shown in FIG Initial state of the arrangement is closed.
- the inner wall of the base 5 is a circumferential V-shaped groove 30 trained, which represents a predetermined breaking seam.
- the front end or suction section 31 engages in the insert 3 a pump device designated overall by reference number 6 on.
- the pump device has conventional means in the area of the suction opening 7, a ball valve 8, which acts upon of an overpressure closes the suction opening 7 and at Exposure to a vacuum from the valve seat so that the front suction chamber 9 by lifting the upper pump part due to the force of the coil spring 10 with from the container chamber 11 can suck in liquid.
- the liquid from fine channels 12 of the upper Part of the pump device and an atomizing nozzle 13 are applied.
- Cap 14 has been removed.
- the known components of the pump device can be found here to be dispensed with.
- a second receiving chamber 15 Between the lower suction end of the pump device 6 and the Bottom 5 of the insert 3 is a second receiving chamber 15, in which, for example, a solution that is not long-term stable in solution Active ingredient of a drug that is liquid in the delivery state freeze-dried form can be kept as long as that Medicines should not be administered.
- the bottle 1 is in its lower area in a cup-shaped Outer cap 16 taken close to the outer wall of the vial.
- the outer cap 16 has at its top End of an outwardly facing circumferential thickening 17 with a lower ring shoulder 18 and at the top of a slope 19.
- An outwardly facing annular shoulder 20 of a pump part 21 is by an inwardly facing annular flange 22nd of a housing part 23 of the pump device 6, which with a cylindrical outer wall 24 partially over the cylindrical outer wall of the outer cap 16 extends.
- the housing part 24 also has a circumferential thickening 25 on its lower end with an overhead ring shoulder 25a and below lying slope 26.
- the annular thickening of the housing part 23 has a radial after inside a little oversize so that the thickening with a certain bias is applied to the outer wall of the outer cap 16.
- a predetermined distance from the thickening 17 of the outer cap is located in the outer wall of the outer cap 16 circumferential annular groove 27a, in the insertion of the pump device into the vial 1 in the liquid dispensing position shown in Figure 2 the thickening of the housing 23 engages. As a result, the delivery position of the pump device is fixed.
- the pump device 6 sits with the one surrounding the suction chamber 9
- the peripheral wall 27 is tight in the insert 3.
- the peripheral wall 27 sits down (in the figures down) in a tubular Projection 28 continues, which is cut away obliquely at its end and the suction opening 7 of the pump device 6 protrudes.
- the invention extends the outer cap 31 in which the container 1 is arranged up to the upper edge of the container neck.
- the container 1 sits with radial play in the outer cap 13 and is non-rotatably connected to it by one of the Bottom of the outer cap 31 projecting web 32 in a corresponding shaped bottom groove of the container 1 engages.
- the outer cap 31 has an axial in its upper end region short threaded section 33, in which a likewise axially short Threaded portion 34 on the inside of the housing part 35 of the Pump device 6 engages.
- a sawtooth thread is preferred for this.
- the bottom 5 of the insert 3 is torn open in that the Housing part 35 is screwed clockwise, opening it an annular extension (39) of another housing part (40) the pump device slides until an end edge 36 of a Housing part 37 on the shoulder portion 38 of the container 1st incident.
- the bottom 5 of the insert 3 is in this end position torn open, as Figure 4 indicates.
- the threaded portion 34 of the housing part 35 is in this Position no longer with the threaded section 33 of the outer cap 31 engaged so that it is not possible for a user to screw the housing part 35 back into the initial state.
Landscapes
- Closures For Containers (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Package Specialized In Special Use (AREA)
- Reciprocating Pumps (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Centrifugal Separators (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Spinning Or Twisting Of Yarns (AREA)
Abstract
Description
Die Erfindung betrifft einen Behälter mit einer Pumpeneinrichtung zur Abgabe eines flüssigen Behälterinhalts, wie beispielsweise eines flüssigen Arzneimittels. Der Behälter hat vorzugsweise die Form eines Fläschchens mit einem Flaschenhals, auf der eine Spraypumpe oder Vakuumpumpe sitzt, die durch Niederdrücken des oberen Pumpenteils in Richtung des Flaschenhalses eine vorbestimmte Menge des flüssigen Behälterinhalts in eine Kammer der Pumpe einsaugt und dann -mit dem nächsten Pumpenhub- aus feinen Kanälen des oberen Pumpenteils ausstößt, wobei die Flüssigkeit an einer Austrittsdüse fein zerstäubt wird. Die Flüssigkeit kann aber auch tropfenweise abgegeben werden. Derartige Pumpen sind beispielsweise zum Einsprühen eines flüssigen Arzneimittels in die Nase weit verbreitet.The invention relates to a container with a pump device for dispensing a liquid container content, such as a liquid drug. The container preferably has the shape of a vial with a bottle neck on which a spray pump or vacuum pump sits by depressing it of the upper pump part in the direction of the bottle neck predetermined amount of the liquid container contents in a chamber of the pump and then - with the next pump stroke - off fine channels of the upper pump part ejects, the liquid is atomized finely at an outlet nozzle. The liquid can also be dispensed drop by drop. such Pumps are used, for example, to spray a liquid drug widespread in the nose.
Bevorzugt betrifft die Erfindung solche Behälter, die im Coextrusions-Blasverfahren hergestellt sind und aus einem starren Außenbehälter und aus einem weichen Innenbeutel bestehen, deren Materialien keine Schweißverbindung miteinander eingehen. Bei den bevorzugten Behältern ist die durch das Abquetschen des schlauchförmigen Vorformlings in der Blasform verschlossene Bodennaht des Innenbeutels in einem nach außen vorstehenden Bodensteg des Außenbehälters eingeklemmt, wobei der Außensteg ebenfalls mittels einer Schweißnaht verschlossen ist, die sich dadurch gebildet hat, daß sich die Schweißnaht des Innenbeutels durch eine Stauwirkung in dem die Bodennaht des Außenbehälters ausbildenden Formabschnitt von der Trennstelle zurückgezogen hat. Die Wand des Außenbehälters enthält Druckausgleichsöffnungen, die beispielsweise durch unverschweißte Schulternähte des Außenbehälters oder dadurch ausgebildet sein können, daß ein Span des Außenbehälters an einem konvexen Abschnitt flach weggeschnitten ist, wobei beim Auftreffen des Messers auf den Innenbeutel der letztere nicht beschädigt, sondern nach innen weggedrückt wird. Bei der allmählichen Abgabe des flüssigen Behälterinhalts zieht sich der Innenbeutel zunehmend zusammen, wobei zum Druckausgleich entsprechend Umgebungsluft durch die Druckausgleichsöffnungen in den Zwischenraum zwischen dem Außenbehälter und den Innenbeutel eintritt.The invention preferably relates to those containers which are produced by the coextrusion blow molding process are made and from a rigid Outer container and consist of a soft inner bag, the Materials do not weld together. at the preferred container is by squeezing the tubular preform sealed in the blow mold Bottom seam of the inner bag in an outwardly protruding Bottom web of the outer container is clamped, the outer web is also closed by means of a weld seam, which itself has formed in that the weld seam of the inner bag due to a jamming effect in the bottom seam of the outer container forming section withdrawn from the separation point Has. The wall of the outer container contains pressure equalization openings, for example through unwelded shoulder seams of the outer container or can be formed in that a Chip of the outer container cut flat on a convex section is, when the knife hits the Inner bag of the latter not damaged, but inside is pushed away. With the gradual release of the liquid The inner bag is increasingly contracting inside the container, whereby for pressure equalization according to ambient air through the Pressure equalization openings in the space between the outer container and the inner bag enters.
Die Erfindung ist jedoch nicht auf die Verwendung eines derartigen Behälters beschränkt, und der Behälter muß auch nicht unbedingt eine Flaschenform mit einem Flaschenhals haben.However, the invention is not based on the use of such Container limited, and the container does not have to necessarily have a bottle shape with a bottle neck.
Der erfindungsgemäße Behälter ist ferner bevorzugt zur Aufnahme eines flüssigen Arzneimittels vorgesehen und wird nachfolgend anhand eines derartigen Beispiels beschrieben, obwohl betont wird, daß er auch zur Aufnahme und Abgabe einer anderen Flüssigkeit geeignet ist, wenn diese aus zwei Substanzen, nämlich einem zunächst in dem Behälter befindlichen Lösungsmittel und einem in einer zweiten Kammer des Behälters zunächst getrennt aufbewahrten, vorzugsweise im festen Zustand befindlichen Wirkstoff mischbar ist.The container according to the invention is also preferred for receiving of a liquid drug is provided and will follow described using such an example, although emphasized is that he will also take up and dispense another liquid is suitable if it consists of two substances, namely one solvent in the container and one in a second chamber of the container, initially kept separately, preferably in the solid state active ingredient is miscible.
Einige pharmazeutische Wirkstoffe wie beispielsweise Hormone sind -wenn sie in einer Flüssigkeit gelöst sind- nicht langzeitstabil, was vor allem dann der Fall ist, wenn keine Konservierungsmittel beigegeben werden können. Um hier Abhilfe zu schaffen, ist es bekannt, solche Wirkstoffe in gefriergetrockneter Form aufzubewahren und vor Gebrauch in ein Lösungsmittel einzugeben, mit dem der Wirkstoff im aufgelösten Zustand ein flüssiges Arzneimittel bildet, das beispielsweise mittels einer Pipette verabreicht werden kann.Some active pharmaceutical ingredients such as hormones are not long-term stable if they are dissolved in a liquid, which is especially the case when there are no preservatives can be added. To remedy this create, it is known to freeze such active ingredients in Store form and in a solvent before use enter with the active ingredient in the dissolved state a liquid Drugs forms, for example, by means of a Pipette can be administered.
Aus der EP 0679443 A1 ist ein Behälter bekannt, in dessen Behälterhals ein rohrförmiger Einsatz angeordnet ist, dessen Boden durch zwei Elastomerlippen verschlossen ist, die unter Vorspannung aneinander anliegen. Der Boden des Einsatzes wird geöffnet, wenn der vordere Saugabschnitt einer Pumpe in den Behälter hineingeschoben wird. Wenn der Behälter gelagert wird, kann die Behälteröffnung mit einer Folie abgedichtet werden, die unmittelbar vor der Benutzung der Pumpe entfernt wird.From EP 0679443 A1 a container is known, in the container neck tubular insert is arranged, the bottom of which is formed by two elastomer lips is closed, which lie against each other under pretension. The bottom of the Insert is opened when the front suction section of a pump in the Container is pushed into it. If the container is stored, the Container opening are sealed with a film that is immediately in front of the Using the pump is removed.
Der vorliegenden Erfindung liegt die Aufgabe zugrunde, einen Behälter mit einer Pumpeneinrichtung anzugeben, der zur Aufnahme und Abgabe einer Flüssigkeit mit einem nicht langzeitstabilen Wirkstoff geeignet ist.The present invention has for its object a container with a Specify the pump device that is used to receive and dispense a liquid an active ingredient that is not stable in the long term.
Diese Aufgabe wird erfindungsgemäß durch die Merkmale des Patentanspruchs 1
gelöst.This object is achieved according to the invention by the features of
Vorteilhafte Ausgestaltung der Erfindung sind in den Unteransprüchen gekennzeichnet.Advantageous embodiments of the invention are in the subclaims characterized.
Erfindungsgemäß ist vorgesehen, daß in der Öffnung des Behälters, bevorzugt in dem Behälterhals, wenn ein solcher vorhanden ist, ein im wesentlichen röhrförmiger Einsatz angeordnet ist, der dicht am Rand der Öffnung anliegt und einen Boden aufweist, der in einem ersten Zustand der Anordnung geschlossen ist und vor der erstmaligen Abgabe des flüssigen Behälterinhalts durch Einwirken einer Kraft geöffnet wird. Ferner ist vorgesehen, daß der vordere Endabschnitt der bevorzugt als Airless-Pumpe vorgesehenen Pumpeneinrichtung in den Einsatz eingreift, wobei die Umfangswand dieses vorderen Endabschnitts bzw. Saugabschnitts dicht an der Wand des Einsatzes anliegt, und wobei die Umfangswand bei Einwirken einer entsprechenden Kraft in axialer Richtung des Behälters gegenüber dem Einsatz verschiebbar ist. Ferner ist vorgesehen, daß sich zwischen dem Boden des Einsatzes und dem Ende der Pumpeneinrichtung eine Aufnahmekammer befindet, in die eine Substanz aufgenommen werden kann, die im geschlossenen Zustand des Bodens von einer in dem übrigen Innenraum des Behälters befindlichen zweiten Substanz getrennt ist. Wenn der Boden des Einsatzes jedoch durch Vorschieben der Pumpeneinrichtung geöffnet bzw. aufgerissen wird, tritt die im Einsatz befindliche Substanz aus dem Einsatz aus und kann mit der Substanz in dem Behälter vermischt werden. Dabei wird in den Einsatz bevorzugt ein gefriergetrockneter Wirkstoff eines Arzneimittels zunächst von einem in dem Behälter befindlichen Lösungsmittels, z.B. sterilem Wasser, isoliert und nach öffnen des Bodens mit dieser Flüssigkeit vermischt. Auf letzteres ist -wie bereits oben erwähnt- die Erfindung aber nicht beschränkt.According to the invention it is provided that in the opening of the container, preferably in the neck of the container, if there is one, essentially one tubular insert is arranged, which abuts the edge of the opening and has a bottom which is closed in a first state of the arrangement and before the first dispensing of the liquid container content by the action of a Force is opened. It is also provided that the front end portion of the preferably used as an airless pump engages, the peripheral wall of this front end portion or Suction section abuts the wall of the insert, and being the peripheral wall upon application of a corresponding force in the axial direction of the container can be moved relative to the insert. It is also provided that between the bottom of the insert and the end of the pump device Receiving chamber is located, in which a substance can be taken, the in the closed state of the floor of one in the rest of the interior of the Container second substance is separated. If the bottom of the But opened by pushing the pump device forward or is torn open, the one in use Substance out of use and can with the substance be mixed in the container. This is in use preferably a freeze-dried active ingredient of a medicament first of all a solvent in the container, e.g. sterile water, isolated and after opening the bottom with mixed this liquid. The latter is - as already mentioned above - but the invention is not limited.
Der im wesentlichen rohrförmige Einsatz hat zweckmäßigerweise eine Zylinderform, wenn auch der Flaschenhals des Behälters und der vordere Gehäuseabschnitt der Pumpeneinrichtung eine entsprechende Zylinderform -allerdings mit größerem bzw. kleineren Durchmesser- hat.The essentially tubular insert has expediently a cylindrical shape, even if the bottle neck of the container and the front housing section of the pump device has a corresponding one Cylindrical shape - but with a larger or smaller one Diameter- has.
Am Boden des Einsatzes ist -bevorzugt an der Innenseite- entweder über den ganzen Umfang umlaufend oder nahezu ganz umlaufend eine Nut ausgebildet, die querschnittlich etwa eine V-Form haben kann und eine Schwächungsnaht bildet, an der bei Einwirken einer Kraft der Boden aufreißt. Besonders bevorzugt ist hierzu, daß die Pumpeneinrichtung einen sich über den vorderen Endbereich mit dem Kugelventil hinaus vorspringenden rohrförmigen Vorsprung aufweist, der mit der umlaufenden Nut des Bodens fluchtet und an seinem freien Ende schräg weggeschnitten ist, so daß der Vorsprung beim Vorschub der Pumpeneinrichtung in den Behälter hinein zunächst nur mit der Spitze des Vorsprungs in die Nut eintritt und mit einer hohen Preßkraft die Naht aufreißt, wobei ein zunehmender Umfangsbereich die geschwächte Naht bei anhaltendem Vorschub weiter aufreißt, so daß schließlich der Boden in der Gebrauchsstellung nach unten klappt und der Inhalt des Einsatzes vollständig freigegeben wird. Der Vorsprung ist vorzugsweise dadurch gebildet, daß die Umfangswand des vorderen Saugbereichs der Pumpeneinrichtung über den Ventilbereich hinaus verlängert wird. On the bottom of the insert, preferably on the inside, is either all the way around or almost all the way round formed a groove which have a V-shaped cross section can and forms a weakening seam on which when exposed to a Force the ground tearing open. It is particularly preferred that the pump device extends over the front end region projecting tubular projection with the ball valve has, which is aligned with the circumferential groove of the bottom and on its free end is cut away obliquely, so that the projection when feeding the pump device into the container only with the tip of the projection into the groove occurs and the seam tears open with a high pressing force, whereby an increasing circumferential area the weakened seam with persistent Feed further tears open, so that finally the bottom in the position of use folds down and the content of the insert is fully released. The protrusion is preferred formed by the peripheral wall of the front suction area the pump device beyond the valve area is extended.
Der Einsatz liegt zweckmäßigerweise mit einer Ringschulter auf der Oberseite des Behälters oder der oberen Randkante des Behälterhalses auf, wenn ein solcher vorhanden ist.The insert expediently lies on a ring shoulder the top of the container or the top edge of the container neck if there is one.
Weiter wird mit großem Vorteil vorgeschlagen, daß an der Außenseite des Behälters eine zusätzliche Umfangswand angeordnet ist, die von einem Gehäuseteil der Pumpeneinrichtung teilweise übergriffen wird, das axial verlagerbar ist. Die zusätzliche Umfangswand ist zweckmäßigerweise Teil einer Außenkappe, die zumindest den unteren Bereich des Behälters umfaßt. Dabei kann sich die Außenkappe auch bis zum oberen Rand des Behälters erstrecken.It is also proposed with great advantage that on the outside an additional peripheral wall is arranged on the container, partially overlapped by a housing part of the pump device that is axially displaceable. The additional peripheral wall is expediently part of an outer cap that comprises at least the lower region of the container. It can the outer cap also extends to the top of the container.
Weiter wird vorgeschlagen, daß die Außenkappe an ihrem oberen Rand eine Verdickung mit einer nach außen ragenden Ringschulter aufweist, während das Gehäuseteil der Pumpeneinrichtung an seinem unteren Rand eine Verdickung mit einer nach innen ragenden Ringschulter hat. Die Verdickung der Außenkappe ist demnach der Innenwand des Gehäuseteils zugewandt, während die Verdickung des Gehäuseteils der Außenwand der Außenkappe zugewandt ist. Im aneinander anliegenden Zustand der beiden Ringschultern befindet sich die Pumpeneinrichtung in der zurückgezogenen Ausgangslage, in der der Boden des Einsatzes geschlossen und die darin aufgenommene Substanz von dem übrigen Innenraum des Behälters getrennt ist.It is further proposed that the outer cap on its upper Edge of a thickening with an outwardly projecting ring shoulder has, while the housing part of the pump device a thickening at the bottom with an inward protrusion Has ring shoulder. The thickening of the outer cap is accordingly facing the inner wall of the housing part while thickening of the housing part faces the outer wall of the outer cap. in the the two ring shoulders are in abutting condition the pump device is in the retracted starting position, in which the bottom of the insert is closed and the one inside Substance separated from the rest of the interior of the container is.
Damit das Gehäuseteil mit seiner Ringschulter die Außenkappe bzw. dessen Verdickung übergreifen kann, wird ferner vorgeschlagen, daß beide Ringschultern an der Außenseiten Schrägen aufweisen, die beim Vorschub des Gehäuseteils in Richtung der Außenkappe aufeinander auftreffen, wodurch der Bereich der Verdickung des Gehäuseteils der Pumpe radial aufgeweitet wird, während das Gehäuseteil mit seiner Verdickung über die Verdickung der Außenkappe gleitet. Auf diese Weise können diese beiden Teil leicht zusammengesetzt werden. So that the housing part with its ring shoulder the outer cap or its thickening can spread, it is also proposed that both ring shoulders have bevels on the outside, which when feeding the housing part in the direction of Outer cap hit each other, creating the area of thickening of the housing part of the pump is expanded radially, while the housing part with its thickening over the thickening the outer cap slides. That way, these two can Part can be assembled easily.
Weiter wird vorgeschlagen, daß entweder die Verdickung der Außenkappe oder die Verdickung des Gehäuseteils ein kleines radiales Übermaß aufweist, derart, daß diese Verdickung mit einer Vorspannung an der zugeordneten Wand des jeweils anderen Teils anliegt. In dieser anderen Wand ist im axialen Abstand von der Verdickung eine umlaufende Nut ausgebildet, in die die Verdickung mit dem radialen übermaß einrastet. Diese Nut definiert die Position der Pumpeneinrichtung, in der der Boden des Einsatzes aufgerissen und aufgeklappt ist und in der sich die Anordnung in dem Zustand befindet, in dem der Behälterinhalt durch die Pumpeneinrichtung ausgebracht werden kann.It is also proposed that either the thickening of the Outer cap or the thickening of the housing part a small has radial excess, such that this thickening with a bias on the associated wall of the other Partial. In this other wall is at an axial distance from the thickening formed a circumferential groove into which the The thickening engages with the radial oversize. This groove defines the position of the pump device in which the bottom of the Is torn open and unfolded and in which the Arrangement is in the state in which the container contents can be applied by the pump device.
Demnach sind durch den Eingriff der Außenkappe mit dem Gehäuseteil der Pumpeneinrichtung zwei axiale Positionen der Pumpeneinrichtung relativ zu dem Behälter begrenzt, nämlich die zurückgezogene Ausgangslage durch das Anliegen der Ringschultern aneinander und die in den Behälter eingeschobene gebrauchsfertige Lage, in der die eine Verdickung in die zugeordnete Nut einrastet.Accordingly, by the engagement of the outer cap with the housing part the pump device two axial positions of the pump device limited relative to the container, namely the withdrawn Initial situation due to the application of the ring shoulders to each other and the ready-to-use inserted into the container Location in which a thickening in the associated groove locks.
In einer besonders bevorzugten Ausführungsform sitzt der Behälter in einer Außenkappe, die bis zum oberen Rand des Behälterhalses reichen kann. Die Außenkappe ist an ihrem oberen Randbereich mit einem Gewinde versehen, das sich bevorzugt an der Außenseite der Außenkappe befindet. Mit diesem Gewinde steht ein Innengewinde eines Gehäuseteils der Pumpeneinrichtung in Eingriff.In a particularly preferred embodiment, the container sits in an outer cap that extends to the top of the container neck can be enough. The outer cap is at its upper edge area provided with a thread that is preferably on the Outside of the outer cap. With this thread is a Internal thread of a housing part of the pump device engages.
Durch Drehen des Gehäuseteils wird die Pumpeneinrichtung mit ihrem Saugabschnitt in den Behälter vorgeschoben, bis eine Ringschulter eines anderen Gehäuseteils der Pumpeneinrichtung auf den Behälter aufläuft, wodurch die Gebrauchsposition der Pumpeneinrichtung definiert ist. In diesem Zustand hat der vordere Endabschnitt der Pumpeneinrichtung den Boden des Einsatzes aufgerissen und aufgeklappt, so daß der Wirkstoff in den Behälter eintreten kann.By turning the housing part, the pump device is also pushed their suction section into the container until one Ring shoulder of another housing part of the pump device runs onto the container, causing the use position of the Pump device is defined. In this state the front end portion of the pump means the bottom of the insert torn open and opened so that the active ingredient in the Container can enter.
Durch diesen Schraubvorgang wird die Pumpeneinrichtung kontinuierlich und glatt mit ihrem Saugabschnitt in den Behälter vorgeschoben, wobei ein Verkanten des Saugabschnitts in dem Einsatz zuverlässig verhindert ist. Die zum Aufreißen des Bodens erforderliche Kraft kann ebenfalls durch den Schraubvorgang auch von weniger geschickten Personen problemlos aufgebracht werden.This screwing process makes the pump device continuous and smoothly pushed into the container with its suction section, tilting the suction section in the insert is reliably prevented. The one required to tear open the floor Force can also be achieved by screwing less skillful people can be easily applied.
Mit großem Vorteil wird vorgeschlagen, daß als Gewinde ein Sägezahngewinde verwendet wird. Die Gewindeabschnitte sind vorzugsweise so kurz, daß in der vorgeschobenen Endstellung das Gewinde des Gehäuseteils über das Gewinde der Außenkappe hinaus geschraubt ist, so daß das Gehäuseteil der Pumpeneinrichtung nicht mehr zurückgeschraubt werden kann. Durch diese Selbsthemmung des Gewindes, das auch durch andere Maßnahmen bewirkt werden kann, ist zuverlässig verhindert, daß die Pumpeneinrichtung aus ihrer Gebrauchsstellung heraus bewegt wird.It is proposed with great advantage that a thread Sawtooth thread is used. The thread sections are preferably so short that in the advanced end position Thread of the housing part beyond the thread of the outer cap is screwed so that the housing part of the pump device can no longer be screwed back. Through this self-locking the thread, which also causes other measures can be reliably prevented that the pump device is moved out of its position of use.
Weitere Einzelheiten der Erfindung ergeben sich aus der nachfolgenden Beschreibung bevorzugter Ausführungsformen der Erfindung und aus der beigefügten Zeichnung. Dabei zeigen:
- Fig. 1
- einen Vertikalschnitt durch eine erste Ausführungsform eines Behälters mit einer Pumpeneinrichtung im Ausgangszustand;
- Fig. 2
- einen Vertikalschnitt durch die Anordnung gemäß Fig. 1 in dem Zustand, in dem der Behälterinhalt ausbringbar ist;
- Fig. 3
- einen Vertikalschnitt durch eine zweite Ausführungsform eines Behälters mit einer Pumpeneinrichtung im Ausgangszustand und
- Fig. 4
- einen Vertikalschnitt durch die Anordnung gemäß Fig. 3 in dem Zustand, in dem der Behälterinhalt aus dem Einsatz ausgetreten ist.
- Fig. 1
- a vertical section through a first embodiment of a container with a pump device in the initial state;
- Fig. 2
- a vertical section through the arrangement of Figure 1 in the state in which the container contents can be dispensed.
- Fig. 3
- a vertical section through a second embodiment of a container with a pump device in the initial state and
- Fig. 4
- a vertical section through the arrangement of FIG. 3 in the state in which the container content has exited the insert.
Die Figuren zeigen einen flaschenförmigen Behälter 1 mit einem
Hals 2, in dem ein Einsatz 3 angeordnet ist, der mit einer nach
außen weisenden Ringschulter 4 auf der Oberkante des Flaschenhalses
2 aufruht. Der Einsatz 3 hat eine kreiszylindrische Form
und liegt dicht an der Innenwand des Behälterhalses 2 an.The figures show a bottle-shaped
Der Einsatz 3 hat einen Boden 5, der in dem in Figur 1 dargestellten
Ausgangszustand der Anordnung geschlossen ist. In der
Innenwand des Bodens 5 ist eine umlaufende V-förmige Nut 30
ausgebildet, die eine Sollbruchnaht darstellt.The
In den Einsatz 3 greift der vordere End- oder Saugabschnitt 31
einer insgesamt mit dem Bezugszeichen 6 bezeichneten Pumpeneinrichtung
ein. Die Pumpeneinrichtung hat auf herkömliche Weise
im Bereich der Ansaugöffnung 7 ein Kugelventil 8, das bei Einwirken
eines Überdrucks die Ansaugöffnung 7 verschließt und bei
Einwirkung eines Unterdrucks von dem Ventilsitz abhebt, so daß
sich die vordere Saugkammer 9 durch Hub des oberen Pumpenteils
infolge der Kraft der Schraubenfeder 10 mit aus der Behälterkammer
11 angesaugter Flüssigkeit füllen kann. Mit einem erneuten
Pumpenhub wird die Flüssigkeit aus feinen Kanälen 12 des oberen
Teils der Pumpeneinrichtung und einer Zerstäubungsdüse 13 ausgebracht.
Zuvor ist natürlich die in den Figuren dargestellte
Kappe 14 abgenommen worden. Auf eine detaillierte Beschreibung
der bekannten Bestandteile der Pumpeneinrichtung kann hier
verzichtet werden. The front end or
Zwischen dem unteren Saugende der Pumpeneinrichtung 6 und dem
Boden 5 des Einsatzes 3 befindet sich eine zweite Aufnahmekammer
15, in der beispielsweise ein in Lösung nicht langzeitstabiler
Wirkstoff eines im Abgabezustand flüssigen Arzneimittels in
gefriergetrockneter Form aufbewahrt werden kann, solange das
Arzneimittel nicht verabreicht werden soll.Between the lower suction end of the
Das Fläschchen 1 ist in seinem unteren Bereich in eine napfförmige
Außenkappe 16 aufgenommen, die dicht an der Außenwandung
des Fläschchens anliegt. Die Außenkappe 16 hat an ihrem oberen
Ende eine nach außen weisende umlaufende Verdickung 17 mit einer
unteren Ringschulter 18 und an der Oberseite einer Schräge 19.The
Eine nach außen weisende Ringschulter 20 eines Pumpenteils 21
wird von einem nach innen weisenden ringförmigen Flansch 22
eines Gehäuseteils 23 der Pumpeneinrichtung 6 übergriffen, das
sich mit einer zylindrischen Außenwand 24 teilweise über die
zylindrische Außenwand der Außenkappe 16 erstreckt. Das Gehäuseteil
24 hat ebenfalls eine umlaufende Verdickung 25 an seinem
unteren Ende mit einer oben liegenden Ringschulter 25a und darunter
liegender Schräge 26.An outwardly facing
In der in Figur 1 dargestellten Ausgangslage der Anordnung liegt
die Ringschulter 25 des Gehäuseteils 23 an der Ringschulter 18
der Außenkappe an. Hierdurch ist die von dem Fläschchen 1 zurückgezogene
Ausgangslage der Pumpeneinrichtung 6 definiert.In the starting position of the arrangement shown in Figure 1
the
Die ringförmige Verdickung des Gehäuseteils 23 hat radial nach
innen ein kleines übermaß, so daß die Verdickung mit einer
gewissen Vorspannung an der Außenwand der Außenkappe 16 anliegt.
In einem vorgegebenen Abstand von der Verdickung 17 der Außenkappe
befindet sich in der Außenwand der Außenkappe 16 eine
umlaufende Ringnut 27a, in die beim Einschub der Pumpeneinrichtung
in das Fläschchen 1 in die in Figur 2 dargestellte Flüssigkeits-Abgabeposition
die Verdickung des Gehäuses 23 einrastet.
Hierdurch wird die Abgabeposition der Pumpeneinrichtung fixiert.The annular thickening of the
Die Pumpeneinrichtung 6 sitzt mit der die Saugkammer 9 umgebenden
Umfangswand 27 dicht in dem Einsatz 3. Die Umfangswand 27
setzt sich (in den Figuren nach unten) in einem rohrförmigen
Vorsprung 28 fort, der an seinem Ende schräg weggeschnitten ist
und die Saugöffnung 7 der Pumpeneinrichtung 6 überragt.The
Beim Einschub der Pumpeneinrichtung in das Fläschchen 1 in die
in Fig. 2 dargestellte Endposition trifft der rohrförmige Vorsprung
28 zunächst mit seiner axial vorderen (in der Figur
linken) Spitze 29 auf den Boden 5 auf, genauer gesagt, in die V-förmige
Nut 30, wobei die Sollbruchnaht aufgerissen wird, bis
der Boden 5 in der aus Figur 2 ersichtlichen Weise nach unten
weggeklappt ist. In diesem Zustand ist der in Kammer 15 befindliche
Wirkstoff freigegeben, so daß er mit einem in der Kammer
11 des Fläschchens 1 befindlichen Lösungsmittel vermischt werden
kann.When inserting the pump device into the
Bei der in den Figuren 3 und 4 dargestellten zweiten Ausführungsform
der Erfindung erstreckt sich die Außenkappe 31, in der
der Behälter 1 angeordnet ist, bis zur Oberkante des Behälterhalses.
Der Behälter 1 sitzt mit radialem Spiel in der Außenkappe
13 und ist mit dieser drehfest verbunden, indem ein vom
Boden der Außenkappe 31 vorstehender Steg 32 in eine entsprechend
geformte Bodennut des Behälters 1 eingreift.In the second embodiment shown in Figures 3 and 4
the invention extends the
Die Außenkappe 31 hat in ihrem oberen Endbereich einen axial
kurzen Gewindeabschnitt 33, in den ein ebenfalls axial kurzer
Gewindeabschnitt 34 an der Innenseite des Gehäuseteils 35 der
Pumpeneinrichtung 6 eingreift. Bevorzugt ist hierfür ein Sägezahngewinde. The
Der Boden 5 des Einsatzes 3 wird dadurch aufgerissen, daß das
Gehäuseteil 35 im Uhrzeigersinn vorgeschraubt wird, wobei es auf
einem ringförmigen Ansatz (39) eines anderen Gehäuseteils (40)
der Pumpeneinrichtung gleitet, bis eine Stirnkante 36 eines
Gehäuseteils 37 auf den Schulterabschnitt 38 des Behälters 1
auftrifft. In dieser Endlage ist der Boden 5 des Einsatzes 3
aufgerissen, wie Figur 4 andeutet.The
Der Gewindeabschnitt 34 des Gehäuseteils 35 steht in dieser
Position nicht mehr mit dem Gewindeabschnitt 33 der Außenkappe
31 in Eingriff, so daß es für einen Benutzer nicht möglich ist,
das Gehäuseteil 35 wieder in den Ausgangszustand zurückzuschrauben.The threaded
Claims (9)
- A container, in whose opening is arranged a pump device for delivering a liquid container content, whereby closely engaging the inner wall of the opening (2) of the container there is a substantially tubular insert (3), which has a base (5), which is closed in an initial state, whereby before putting the pump device (6) into operation, by advancing a front suction section of the pump device (6), which engages in the insert (3) and whose peripheral wall (27) closely engages the inner wall of the insert (3), the base is opened by direct contact with the suction section, characterised in that located within the insert (3) above its base (5) there is a receiving chamber (15) for an active substance, which is separated from the liquid container contents before the opening of the base and enters into it after the opening process.
- A container with a pump device as claimed in Claim 1, characterised in that the base (5) of the insert (3) has a peripheral groove (30).
- A container with a pump device as claimed in Claim 1 or 2, characterised in that the peripheral wall (27) of the end section of the pump device (6) has a tubular projection (28), which is aligned with the groove (30) in the base (5) and is obliquely cut away.
- A container with a pump device as claimed in one of Claims 1 to 3, characterised in that, on its outer surface, the container (1) has an additional peripheral wall (16), which is part of an external cap (16), which surrounds at least the lower region of the container (1) and that a housing portion (23) of the pump device (6) is in axially movable engagement with the peripheral wall (16).
- A container with a pump device as claimed in Claim 4, characterised in that the external cap (16) has, on its upper edge, an outwardly projecting annular shoulder (18) and the housing portion (23) has, on its lower edge, an inwardly projecting annular shoulder (25).
- A container with a pump device as claimed in Claim 5, characterised in that the annular shoulder (18) on the external cap (16) or the annular shoulder (25) on the housing portion (23) has a small radial oversize so that it engages the wall of the housing portion (23) or the external cap (16) under a preload, whereby the latter has a peripheral groove (27), axially spaced from its annular shoulder, for engaging the other annular shoulder.
- A container with a pump device as claimed in one of Claims 1 to 6, characterised in that the container (1) is arranged in an external cap (31), which is provided with a screwthread (34) and with which a housing portion (35) of the pump device (6) is in threaded engagement.
- A container with a pump device as claimed in Claim 7, characterised in that the screwthread (33, 34) on the external cap (31) and the housing (35) is self-locking in the screwed-in end position.
- A container with a pump device as claimed in Claim 7 or 8, characterised in that the container (1) is rotationally fixedly situated in the external cap (31).
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742559A DE19742559C2 (en) | 1997-09-26 | 1997-09-26 | Container with a pump |
AT98104631T ATE248660T1 (en) | 1997-09-26 | 1998-03-14 | CONTAINER WITH SEALED INSERT AND PUMP TO OPEN THE SEAL |
PT98104631T PT904847E (en) | 1997-09-26 | 1998-03-14 | RECIPE WITH SEALED INSERTION PART AND PUMP TO BREAK SEAL |
EP98104631A EP0904847B1 (en) | 1997-09-26 | 1998-03-14 | Container with sealed insert and pump for breaking the seal |
ES98104631T ES2206776T3 (en) | 1997-09-26 | 1998-03-14 | CONTAINER WITH A CLOSED INSERT AND PUMP TO OPEN THE CLOSURE. |
DK98104631T DK0904847T3 (en) | 1997-09-26 | 1998-03-14 | Container with sealed insert and pump to break the seal |
DE59809472T DE59809472D1 (en) | 1997-09-26 | 1998-03-14 | Container with sealed insert and pump to open the seal |
CZ20000956A CZ297286B6 (en) | 1997-09-26 | 1998-08-21 | Container provided with a pump |
JP2000513677A JP4231623B2 (en) | 1997-09-26 | 1998-08-21 | Container with pump |
RU2000110627/12A RU2201296C2 (en) | 1997-09-26 | 1998-08-21 | Container with pump |
AU96204/98A AU731460B2 (en) | 1997-09-26 | 1998-08-21 | Container comprising a pump |
US09/508,893 US6412659B1 (en) | 1997-09-26 | 1998-08-21 | Container and pump assembly |
PCT/DE1998/002444 WO1999016552A1 (en) | 1997-09-26 | 1998-08-21 | Container with a sealed insert, and pump for opening said sealing |
CA2303880A CA2303880C (en) | 1997-09-26 | 1998-08-21 | Container comprising a pump |
BR9812367-0A BR9812367A (en) | 1997-09-26 | 1998-08-21 | Container with a sealed seal and pump to cover the seal |
TR2000/00857T TR200000857T2 (en) | 1997-09-26 | 1998-08-21 | Container with a pump. |
UA2000042377A UA53752C2 (en) | 1997-09-26 | 1998-08-21 | Container containing a pump |
SK411-2000A SK286670B6 (en) | 1997-09-26 | 1998-08-21 | Container with a sealed insert, and pump for opening said sealing |
HU0003839A HU223435B1 (en) | 1997-09-26 | 1998-08-21 | Container with a sealed insert, and pump for opening said sealing |
CN98809483A CN1112262C (en) | 1997-09-26 | 1998-08-21 | Container with a sealed inset, and pump for opening said sealing |
NO20001467A NO319538B1 (en) | 1997-09-26 | 2000-03-21 | Container containing, in an aperture, a pumping device for ejecting a liquid container contents |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742559A DE19742559C2 (en) | 1997-09-26 | 1997-09-26 | Container with a pump |
DE19742559 | 1997-09-26 | ||
EP98104631A EP0904847B1 (en) | 1997-09-26 | 1998-03-14 | Container with sealed insert and pump for breaking the seal |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0904847A1 EP0904847A1 (en) | 1999-03-31 |
EP0904847B1 true EP0904847B1 (en) | 2003-09-03 |
Family
ID=26040344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98104631A Expired - Lifetime EP0904847B1 (en) | 1997-09-26 | 1998-03-14 | Container with sealed insert and pump for breaking the seal |
Country Status (20)
Country | Link |
---|---|
US (1) | US6412659B1 (en) |
EP (1) | EP0904847B1 (en) |
JP (1) | JP4231623B2 (en) |
CN (1) | CN1112262C (en) |
AT (1) | ATE248660T1 (en) |
AU (1) | AU731460B2 (en) |
BR (1) | BR9812367A (en) |
CA (1) | CA2303880C (en) |
CZ (1) | CZ297286B6 (en) |
DE (2) | DE19742559C2 (en) |
DK (1) | DK0904847T3 (en) |
ES (1) | ES2206776T3 (en) |
HU (1) | HU223435B1 (en) |
NO (1) | NO319538B1 (en) |
PT (1) | PT904847E (en) |
RU (1) | RU2201296C2 (en) |
SK (1) | SK286670B6 (en) |
TR (1) | TR200000857T2 (en) |
UA (1) | UA53752C2 (en) |
WO (1) | WO1999016552A1 (en) |
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-
1997
- 1997-09-26 DE DE19742559A patent/DE19742559C2/en not_active Expired - Fee Related
-
1998
- 1998-03-14 DK DK98104631T patent/DK0904847T3/en active
- 1998-03-14 DE DE59809472T patent/DE59809472D1/en not_active Expired - Lifetime
- 1998-03-14 EP EP98104631A patent/EP0904847B1/en not_active Expired - Lifetime
- 1998-03-14 ES ES98104631T patent/ES2206776T3/en not_active Expired - Lifetime
- 1998-03-14 PT PT98104631T patent/PT904847E/en unknown
- 1998-03-14 AT AT98104631T patent/ATE248660T1/en active
- 1998-08-21 RU RU2000110627/12A patent/RU2201296C2/en not_active IP Right Cessation
- 1998-08-21 HU HU0003839A patent/HU223435B1/en not_active IP Right Cessation
- 1998-08-21 JP JP2000513677A patent/JP4231623B2/en not_active Expired - Fee Related
- 1998-08-21 CN CN98809483A patent/CN1112262C/en not_active Expired - Fee Related
- 1998-08-21 CA CA2303880A patent/CA2303880C/en not_active Expired - Fee Related
- 1998-08-21 TR TR2000/00857T patent/TR200000857T2/en unknown
- 1998-08-21 SK SK411-2000A patent/SK286670B6/en not_active IP Right Cessation
- 1998-08-21 UA UA2000042377A patent/UA53752C2/en unknown
- 1998-08-21 WO PCT/DE1998/002444 patent/WO1999016552A1/en active IP Right Grant
- 1998-08-21 CZ CZ20000956A patent/CZ297286B6/en not_active IP Right Cessation
- 1998-08-21 BR BR9812367-0A patent/BR9812367A/en not_active IP Right Cessation
- 1998-08-21 AU AU96204/98A patent/AU731460B2/en not_active Ceased
- 1998-08-21 US US09/508,893 patent/US6412659B1/en not_active Expired - Fee Related
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2000
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HU223435B1 (en) | 2004-07-28 |
HUP0003839A2 (en) | 2001-02-28 |
DE19742559C2 (en) | 1999-08-05 |
NO20001467L (en) | 2000-03-21 |
UA53752C2 (en) | 2003-02-17 |
ES2206776T3 (en) | 2004-05-16 |
RU2201296C2 (en) | 2003-03-27 |
CN1112262C (en) | 2003-06-25 |
JP2001518428A (en) | 2001-10-16 |
SK286670B6 (en) | 2009-03-05 |
US6412659B1 (en) | 2002-07-02 |
HUP0003839A3 (en) | 2001-04-28 |
WO1999016552A1 (en) | 1999-04-08 |
CZ297286B6 (en) | 2006-10-11 |
BR9812367A (en) | 2000-09-19 |
CA2303880A1 (en) | 1999-04-08 |
AU9620498A (en) | 1999-04-23 |
CA2303880C (en) | 2010-04-27 |
DE59809472D1 (en) | 2003-10-09 |
SK4112000A3 (en) | 2000-09-12 |
ATE248660T1 (en) | 2003-09-15 |
EP0904847A1 (en) | 1999-03-31 |
DE19742559A1 (en) | 1999-05-06 |
DK0904847T3 (en) | 2004-01-12 |
CN1271301A (en) | 2000-10-25 |
NO319538B1 (en) | 2005-08-29 |
TR200000857T2 (en) | 2000-11-21 |
NO20001467D0 (en) | 2000-03-21 |
AU731460B2 (en) | 2001-03-29 |
CZ2000956A3 (en) | 2001-06-13 |
PT904847E (en) | 2004-01-30 |
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