EP0898951A2 - Dispositif d'accès vers un liquide et méthode pour préparer un médicament liquide - Google Patents

Dispositif d'accès vers un liquide et méthode pour préparer un médicament liquide Download PDF

Info

Publication number
EP0898951A2
EP0898951A2 EP19980115546 EP98115546A EP0898951A2 EP 0898951 A2 EP0898951 A2 EP 0898951A2 EP 19980115546 EP19980115546 EP 19980115546 EP 98115546 A EP98115546 A EP 98115546A EP 0898951 A2 EP0898951 A2 EP 0898951A2
Authority
EP
European Patent Office
Prior art keywords
ampoule
cannula
vial
adapter
syringe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP19980115546
Other languages
German (de)
English (en)
Other versions
EP0898951B1 (fr
EP0898951A3 (fr
Inventor
Fredy Zinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medimop Medical Projects Ltd
Original Assignee
Medimop Medical Projects Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimop Medical Projects Ltd filed Critical Medimop Medical Projects Ltd
Publication of EP0898951A2 publication Critical patent/EP0898951A2/fr
Publication of EP0898951A3 publication Critical patent/EP0898951A3/fr
Application granted granted Critical
Publication of EP0898951B1 publication Critical patent/EP0898951B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/065—Rigid ampoules, e.g. glass ampoules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end

Definitions

  • the present invention relates to a fluid access assembly and a method for preparing a liquid drug.
  • a fluid access assembly (10) having a vial access pin (12) and an ampoule access tube (14) for enabling access to a liquid drug contained either in a vial or an ampoule, respectively.
  • the vial access pin (12) has a mounting hub (20) constituted by a female Luer connector, a flange (30) and a cannula (36) with a piercing end and on which the ampoule access tube (14) is sealingly and detachably mounted for aspiration of an ampoule's contents.
  • the fluid access assembly does not facilitate neither the handling nor the discarding of a spent vessel and particularly an ampoule. In particular, it is relatively difficult to slide an opened ampoule's opened end which is of a small cross section area onto the ampoule access tube whilst its attendant exposed sharp edge when opened further militates against convenient use and its discarding when spent.
  • a needle is typically attached to an initially empty syringe for insertion into a previously opened ampoule for aspirating its contents thereinto. Thereafter, the syringe is employed for puncturing a vial's stopper so that the syringe's contents can be injected thereinto for mixing with the vial's contents. Finally, the vial's contents are aspirated into the syringe for injection to a patient, another vial or a Y-site fitting of an intravenous set.
  • the needle which is required for a subsequent step is often shorter than an ampoule and therefore militates against aspirating all of its contents.
  • a fluid access assembly for use with a syringe, a vial having a stopper and/or an ampoule with a frangible end and a sealed end, the assembly comprising:
  • the ampoule adapter of the present invention affords easier handling of an ampoule by virtue of its gripping members which facilitates sliding an ampoule onto its cannula. Additionally, the body portion of the ampoule adapter precludes injury from an opened ampoule's exposed sharp edge during handling and also provides for safer discarding of a spent ampoule together therewith.
  • the fluid access assembly of the present invention can be employed as a universal adapter for use with either an ampoule or a vial and can be employed for mixing liquid drugs in a convenient manner.
  • a method for preparing a syringe with a liquid drug from one component contained in a vial having a stopper and another component contained in an ampoule having a frangible end and a sealed end comprising the following steps:
  • the method of the present invention provides for a convenient preparation of a liquid drug mixed from at least two components inter alia by the fluid access assembly of the present invention thereby affording safer and easier handling of spent parts and in particular a spent ampoule.
  • a fluid access assembly 1 includes a vial adapter 2 and an ampoule adapter 3 for preparing a syringe 4 with a liquid drug mixed from a first component stored in a vial 6 having a mouth portion 7 housing a rubber stopper 8 and a second component stored in an ampoule 9 having a frangible end 10 and a sealed end 11.
  • the vial 6 contains a dry powder, however, it can equally contain a liquid component.
  • the vial adapter 2 has a cannula 12 having a female Luer connector 13 (constituting a proximal portion) for sealingly receiving a syringe's male Luer connector and a puncturing member 14 (constituting a distal portion) for piercing the vial's stopper 8.
  • the cannula 12 has a flange 16 disposed along a central portion thereof, the flange 16 having four resiliently flexible gripping members 17 shaped and dimensioned to snap fit under the vial's mouth portion 7 on the positive insertion of the vial 6 into the vial adapter 2 (see Figure 4).
  • the cannula 12 is dimensioned so as to be slightly longer than the thickness of the vial's stopper 8 (see Figure 4) for facilitating aspiration all of the vial's contents.
  • the ampoule adapter 3 has a tubular shroud 18 constituting a body portion and attached to a cannula 19 having a proximal portion 19A and a distal portion 19B terminating in a V-shaped tip 21, the shroud 18 having a flange 22 with a downward depending rim 23 substantially co-directional with the cannula 19.
  • Two pairs of oppositely disposed gripping members 24 downwardly depend from the rim 23 and are substantially co-directional and co-extensive with the cannula 19.
  • the ampoule adapter 3 is longitudinally dimensioned to receive substantially the entire opened ampoule 6 when fully inserted therein i.e. when further insertion is prevented by the cannula tip 21 abutting against the ampoule's sealed end 11. On such insertion, the ampoule's opened end is received in the shroud 18 and the gripping members 24 friction fit grip substantially its entire periphery (see Figure 3).
  • the ampoule adapter 3 is detachably mounted on the vial adapter 2 by means of its cannula's proximal portion 19A being initially sealingly and detachably mounted on the puncturing member 14.
  • the use of the fluid access assembly 1 for preparing an initially empty syringe with a reconstituted drug is now described with reference to Figures 5A-5F.
  • the syringe 4 is inserted into the ampoule adapter's female Luer connector 13 (see Figure 5A).
  • the ampoule 9 is broken open and fully slided up the cannula 19 until the cannula's tip 21 abuts against its sealed end 11 whereby its opened end 10 is contained within the ampoule adapter's shroud 18 and its lower portion is gripped by the gripping members 24 (see Figure 5A).
  • the ampoule's contents are aspirated into the syringe 4 (see Figure 5B).
  • the ampoule adapter 3 is detached from the vial adapter 2 together with spent ampoule 9 and discarded (see Figure 5C).
  • the vial 6 is positively inserted into the vial adapter 2 so that its puncturing member 14 punctures the vial's stopper 8 (see Figure 5D).
  • the syringe's contents are injected into the vial 6 which is then shaken so as to reconstitute the dry powder concentrate contained therein.
  • the reconstituted drug is aspirated into the syringe 4 which is then removed from the vial adapter 2 which is then discarded together with the spent vial 6.
  • an ampoule adapter can have a telescopic cannula whereby it is suitable for use with ampoules of different lengths.
  • Figures 6A and 6B show an ampoule adapter 26 having a cannula 27 with a proximal portion 27A rigidly attached to its shroud 18 and a distal portion 27B slidingly mounted on the proximal portion 27A, the distal portion 27B being initially extendingly mounted on the proximal portion 27A for sliding up thereon on the full insertion of a short ampoule 28 into the ampoule adapter 26.
  • Figures 7A and 7B show an ampoule adapter 29 having a cannula 31 with an initially extended compressible bellows-like portion 31A whereupon the bellows-like portion 31A is at least partly compacted on the full insertion of the short ampoule 28 into the ampoule adapter 29.
  • an ampoule adapter can have gripping members suitable for use with ampoules of different widths.
  • Figures 8A-8C show an ampoule adapter 32 with gripping members 33 each having a lower portion 33A urgable from a normal inwardly radially disposed state toward the cannula 19 for gripping a small diameter ampoule 34 (see Figure 8B) to a flexed outwardly radially disposed state for gripping a large diameter ampoule 36 (see Figure 8C).
  • Figures 9A-9D shows an ampoule adapter 37 with gripping members 38 each having a flange portion 38A substantially co-extensive therewith and resiliently foldable from a normally inwardly radially disposed state for gripping the small diameter ampoule 34 (see Figures 9A and 9B) to a flexed circumferentially disposed state for gripping the large diameter ampoule 36 (see Figures 9C and 9D).
  • the syringe can initially contain a liquid drug component whilst the ampoule can contain a dry powder.
  • the spent vial can be removed whereby the vial adapter can then be inserted into another vial or a Y-site fitting of an intravenous set.

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP19980115546 1997-08-22 1998-08-18 Dispositif d'accès vers un liquide et méthode pour remplir une sirenge avec un médicament liquide Expired - Lifetime EP0898951B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL12160597 1997-08-22
IL12160597A IL121605A (en) 1997-08-22 1997-08-22 Fluid access assembly and a method for preparing a liquid drug

Publications (3)

Publication Number Publication Date
EP0898951A2 true EP0898951A2 (fr) 1999-03-03
EP0898951A3 EP0898951A3 (fr) 1999-11-10
EP0898951B1 EP0898951B1 (fr) 2002-11-13

Family

ID=11070540

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19980115546 Expired - Lifetime EP0898951B1 (fr) 1997-08-22 1998-08-18 Dispositif d'accès vers un liquide et méthode pour remplir une sirenge avec un médicament liquide

Country Status (3)

Country Link
EP (1) EP0898951B1 (fr)
DE (1) DE69809352T2 (fr)
IL (1) IL121605A (fr)

Cited By (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001080929A1 (fr) * 2000-04-27 2001-11-01 David William Parker Chargement de seringues hypodermiques au moyen d'une substance a injecter
JP2005516696A (ja) * 2002-02-08 2005-06-09 アラリス メディカル システムズ，インコーポレイテッド 様々な寸法のバイアル封緘部と共に使用する針なし弁を有するバイアル・アダプタ
US7326194B2 (en) 1995-03-20 2008-02-05 Medimop Medical Projects Ltd. Fluid transfer device
USD616984S1 (en) 2009-07-02 2010-06-01 Medimop Medical Projects Ltd. Vial adapter having side windows
USD630732S1 (en) 2009-09-29 2011-01-11 Medimop Medical Projects Ltd. Vial adapter with female connector
USD641080S1 (en) 2009-03-31 2011-07-05 Medimop Medical Projects Ltd. Medical device having syringe port with locking mechanism
US8016809B2 (en) 2007-09-25 2011-09-13 Medimop Medical Projects Ltd. Liquid drug delivery devices for use with syringes with widened distal tips
US8021325B2 (en) 2004-04-29 2011-09-20 Medimop Medical Projects Ltd. Liquid drug medical device
US8070739B2 (en) 2005-08-11 2011-12-06 Medimop Medical Projects Ltd. Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials
USD669980S1 (en) 2010-10-15 2012-10-30 Medimop Medical Projects Ltd. Vented vial adapter
US8317743B2 (en) 2007-09-18 2012-11-27 Medimop Medical Projects Ltd. Medicament mixing and injection apparatus
USD674088S1 (en) 2012-02-13 2013-01-08 Medimop Medical Projects Ltd. Vial adapter
US8435210B2 (en) 2007-04-17 2013-05-07 Medimop Medical Projects Ltd. Fluid control device with manually depressed actuator
US8608723B2 (en) 2009-11-12 2013-12-17 Medimop Medical Projects Ltd. Fluid transfer devices with sealing arrangement
US8684994B2 (en) 2010-02-24 2014-04-01 Medimop Medical Projects Ltd. Fluid transfer assembly with venting arrangement
US8752598B2 (en) 2011-04-17 2014-06-17 Medimop Medical Projects Ltd. Liquid drug transfer assembly
US8753325B2 (en) 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter
US8852145B2 (en) 2010-11-14 2014-10-07 Medimop Medical Projects, Ltd. Inline liquid drug medical device having rotary flow control member
US8905994B1 (en) 2011-10-11 2014-12-09 Medimop Medical Projects, Ltd. Valve assembly for use with liquid container and drug vial
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
WO2015021499A1 (fr) 2013-08-13 2015-02-19 Noble House Group Pty. Ltd. Capuchon de prélèvement universel
US8998875B2 (en) 2009-10-01 2015-04-07 Medimop Medical Projects Ltd. Vial assemblage with vial and pre-attached fluid transfer device
USD734868S1 (en) 2012-11-27 2015-07-21 Medimop Medical Projects Ltd. Drug vial adapter with downwardly depending stopper
USD737436S1 (en) 2012-02-13 2015-08-25 Medimop Medical Projects Ltd. Liquid drug reconstitution assembly
US9132063B2 (en) 2009-11-12 2015-09-15 Medimop Medical Projects Ltd. Inline liquid drug medical devices with linear displaceable sliding flow control member
US9283324B2 (en) 2012-04-05 2016-03-15 Medimop Medical Projects, Ltd Fluid transfer devices having cartridge port with cartridge ejection arrangement
US9339438B2 (en) 2012-09-13 2016-05-17 Medimop Medical Projects Ltd. Telescopic female drug vial adapter
USD757933S1 (en) 2014-09-11 2016-05-31 Medimop Medical Projects Ltd. Dual vial adapter assemblage
USD765837S1 (en) 2013-08-07 2016-09-06 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
USD767124S1 (en) 2013-08-07 2016-09-20 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
US9795536B2 (en) 2012-08-26 2017-10-24 Medimop Medical Projects, Ltd. Liquid drug transfer devices employing manual rotation for dual flow communication step actuations
US9801786B2 (en) 2013-04-14 2017-10-31 Medimop Medical Projects Ltd. Drug container closure for mounting on open-topped drug container to form drug reconstitution assemblage for use with needleless syringe
USD801522S1 (en) 2015-11-09 2017-10-31 Medimop Medical Projects Ltd. Fluid transfer assembly
US9839580B2 (en) 2012-08-26 2017-12-12 Medimop Medical Projects, Ltd. Liquid drug transfer devices
US9943463B2 (en) 2013-05-10 2018-04-17 West Pharma. Services IL, Ltd. Medical devices including vial adapter with inline dry drug module
GB2561542A (en) * 2017-03-17 2018-10-24 Rabmed As Ampoule closure
USD832430S1 (en) 2016-11-15 2018-10-30 West Pharma. Services IL, Ltd. Dual vial adapter assemblage
US10278897B2 (en) 2015-11-25 2019-05-07 West Pharma. Services IL, Ltd. Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
US10285907B2 (en) 2015-01-05 2019-05-14 West Pharma. Services IL, Ltd. Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
US10357429B2 (en) 2015-07-16 2019-07-23 West Pharma. Services IL, Ltd. Liquid drug transfer devices for secure telescopic snap fit on injection vials
US10646404B2 (en) 2016-05-24 2020-05-12 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including identical twin vial adapters
US10688295B2 (en) 2013-08-07 2020-06-23 West Pharma. Services IL, Ltd. Liquid transfer devices for use with infusion liquid containers
US10765604B2 (en) 2016-05-24 2020-09-08 West Pharma. Services IL, Ltd. Drug vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter
US10772798B2 (en) 2016-12-06 2020-09-15 West Pharma Services Il, Ltd. Liquid transfer device with integral telescopic vial adapter for use with infusion liquid container and discrete injection vial
US10806671B2 (en) 2016-08-21 2020-10-20 West Pharma. Services IL, Ltd. Syringe assembly
US10806667B2 (en) 2016-06-06 2020-10-20 West Pharma. Services IL, Ltd. Fluid transfer devices for filling drug pump cartridges with liquid drug contents
GB2584889A (en) * 2019-06-19 2020-12-23 Rabmed As Ampoule closure
US10945921B2 (en) 2017-03-29 2021-03-16 West Pharma. Services IL, Ltd. User actuated liquid drug transfer devices for use in ready-to-use (RTU) liquid drug transfer assemblages
USD917693S1 (en) 2018-07-06 2021-04-27 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923782S1 (en) 2019-01-17 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD923812S1 (en) 2019-01-16 2021-06-29 West Pharma. Services IL, Ltd. Medication mixing apparatus
USD954253S1 (en) 2019-04-30 2022-06-07 West Pharma. Services IL, Ltd. Liquid transfer device
USD956958S1 (en) 2020-07-13 2022-07-05 West Pharma. Services IL, Ltd. Liquid transfer device
USD983366S1 (en) 2021-07-15 2023-04-11 Kairish Innotech Private Limited Vial adapter
US11642285B2 (en) 2017-09-29 2023-05-09 West Pharma. Services IL, Ltd. Dual vial adapter assemblages including twin vented female vial adapters
US11918542B2 (en) 2019-01-31 2024-03-05 West Pharma. Services IL, Ltd. Liquid transfer device
USD1043974S1 (en) 2022-04-22 2024-09-24 West Pharma. Services IL, Ltd. Liquid transfer device

Families Citing this family (3)

* Cited by examiner, † Cited by third party
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CA2834152C (fr) 2006-05-25 2016-07-05 Bayer Healthcare Llc Dispositif de reconstitution
WO2012150587A1 (fr) * 2011-05-03 2012-11-08 Sabiedriba Ar Ierobezotu Atbildibu "Sdmd" Adaptateur pour flacon
WO2015002646A1 (fr) * 2013-07-02 2015-01-08 Hoftman Mike Moshe Dispositif pour prendre et administrer en toute sécurité des liquides par une seringue

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0637443A1 (fr) 1993-08-02 1995-02-08 Becton, Dickinson and Company Dispositif d'accès au médicament d'une ampoule

Family Cites Families (1)

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AU8880991A (en) * 1990-12-04 1992-06-11 Automatic Liquid Packaging, Inc. Hermetically sealed vial

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0637443A1 (fr) 1993-08-02 1995-02-08 Becton, Dickinson and Company Dispositif d'accès au médicament d'une ampoule

Cited By (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7879018B2 (en) 1995-03-20 2011-02-01 Medimop Medical Projects, Ltd. Fluid transfer device
US7326194B2 (en) 1995-03-20 2008-02-05 Medimop Medical Projects Ltd. Fluid transfer device
US7632261B2 (en) 1995-03-20 2009-12-15 Medimop Medical Projects, Ltd. Fluid transfer device
WO2001080929A1 (fr) * 2000-04-27 2001-11-01 David William Parker Chargement de seringues hypodermiques au moyen d'une substance a injecter
JP2005516696A (ja) * 2002-02-08 2005-06-09 アラリス メディカル システムズ，インコーポレイテッド 様々な寸法のバイアル封緘部と共に使用する針なし弁を有するバイアル・アダプタ
US8066688B2 (en) 2004-04-29 2011-11-29 Medimop Medical Projects Ltd. Liquid drug medical device
US8021325B2 (en) 2004-04-29 2011-09-20 Medimop Medical Projects Ltd. Liquid drug medical device
US8070739B2 (en) 2005-08-11 2011-12-06 Medimop Medical Projects Ltd. Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials
US8435210B2 (en) 2007-04-17 2013-05-07 Medimop Medical Projects Ltd. Fluid control device with manually depressed actuator
US8317743B2 (en) 2007-09-18 2012-11-27 Medimop Medical Projects Ltd. Medicament mixing and injection apparatus
US8016809B2 (en) 2007-09-25 2011-09-13 Medimop Medical Projects Ltd. Liquid drug delivery devices for use with syringes with widened distal tips
USD641080S1 (en) 2009-03-31 2011-07-05 Medimop Medical Projects Ltd. Medical device having syringe port with locking mechanism
USD616984S1 (en) 2009-07-02 2010-06-01 Medimop Medical Projects Ltd. Vial adapter having side windows
USD630732S1 (en) 2009-09-29 2011-01-11 Medimop Medical Projects Ltd. Vial adapter with female connector
US8998875B2 (en) 2009-10-01 2015-04-07 Medimop Medical Projects Ltd. Vial assemblage with vial and pre-attached fluid transfer device
US9132063B2 (en) 2009-11-12 2015-09-15 Medimop Medical Projects Ltd. Inline liquid drug medical devices with linear displaceable sliding flow control member
US8608723B2 (en) 2009-11-12 2013-12-17 Medimop Medical Projects Ltd. Fluid transfer devices with sealing arrangement
US8753325B2 (en) 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter
US8684994B2 (en) 2010-02-24 2014-04-01 Medimop Medical Projects Ltd. Fluid transfer assembly with venting arrangement
USD669980S1 (en) 2010-10-15 2012-10-30 Medimop Medical Projects Ltd. Vented vial adapter
US8852145B2 (en) 2010-11-14 2014-10-07 Medimop Medical Projects, Ltd. Inline liquid drug medical device having rotary flow control member
US8752598B2 (en) 2011-04-17 2014-06-17 Medimop Medical Projects Ltd. Liquid drug transfer assembly
US8905994B1 (en) 2011-10-11 2014-12-09 Medimop Medical Projects, Ltd. Valve assembly for use with liquid container and drug vial
USD737436S1 (en) 2012-02-13 2015-08-25 Medimop Medical Projects Ltd. Liquid drug reconstitution assembly
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
USD674088S1 (en) 2012-02-13 2013-01-08 Medimop Medical Projects Ltd. Vial adapter
US9283324B2 (en) 2012-04-05 2016-03-15 Medimop Medical Projects, Ltd Fluid transfer devices having cartridge port with cartridge ejection arrangement
US10299990B2 (en) 2012-08-26 2019-05-28 West Pharma. Services IL, Ltd. Liquid drug transfer devices
US9795536B2 (en) 2012-08-26 2017-10-24 Medimop Medical Projects, Ltd. Liquid drug transfer devices employing manual rotation for dual flow communication step actuations
US9839580B2 (en) 2012-08-26 2017-12-12 Medimop Medical Projects, Ltd. Liquid drug transfer devices
US9339438B2 (en) 2012-09-13 2016-05-17 Medimop Medical Projects Ltd. Telescopic female drug vial adapter
USD734868S1 (en) 2012-11-27 2015-07-21 Medimop Medical Projects Ltd. Drug vial adapter with downwardly depending stopper
US9801786B2 (en) 2013-04-14 2017-10-31 Medimop Medical Projects Ltd. Drug container closure for mounting on open-topped drug container to form drug reconstitution assemblage for use with needleless syringe
US9943463B2 (en) 2013-05-10 2018-04-17 West Pharma. Services IL, Ltd. Medical devices including vial adapter with inline dry drug module
USD767124S1 (en) 2013-08-07 2016-09-20 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
USD765837S1 (en) 2013-08-07 2016-09-06 Medimop Medical Projects Ltd. Liquid transfer device with integral vial adapter
US10688295B2 (en) 2013-08-07 2020-06-23 West Pharma. Services IL, Ltd. Liquid transfer devices for use with infusion liquid containers
EP3033139A4 (fr) * 2013-08-13 2017-03-15 Noble House Group Pty. Ltd. Capuchon de prélèvement universel
WO2015021499A1 (fr) 2013-08-13 2015-02-19 Noble House Group Pty. Ltd. Capuchon de prélèvement universel
USD757933S1 (en) 2014-09-11 2016-05-31 Medimop Medical Projects Ltd. Dual vial adapter assemblage
US10285907B2 (en) 2015-01-05 2019-05-14 West Pharma. Services IL, Ltd. Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
US10357429B2 (en) 2015-07-16 2019-07-23 West Pharma. Services IL, Ltd. Liquid drug transfer devices for secure telescopic snap fit on injection vials
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Also Published As

Publication number Publication date
DE69809352D1 (de) 2002-12-19
EP0898951B1 (fr) 2002-11-13
EP0898951A3 (fr) 1999-11-10
IL121605A (en) 2001-03-19
DE69809352T2 (de) 2003-03-20
IL121605A0 (en) 1998-02-08

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