EP0877554A4 - - Google Patents

Info

Publication number
EP0877554A4
EP0877554A4 EP96937010A EP96937010A EP0877554A4 EP 0877554 A4 EP0877554 A4 EP 0877554A4 EP 96937010 A EP96937010 A EP 96937010A EP 96937010 A EP96937010 A EP 96937010A EP 0877554 A4 EP0877554 A4 EP 0877554A4
Authority
EP
European Patent Office
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96937010A
Other versions
EP0877554A1 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603833.6A external-priority patent/GB9603833D0/en
Priority claimed from GBGB9605156.0A external-priority patent/GB9605156D0/en
Application filed filed Critical
Publication of EP0877554A1 publication Critical patent/EP0877554A1/en
Publication of EP0877554A4 publication Critical patent/EP0877554A4/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP96937010A 1995-10-31 1996-10-28 Triterpene derivatives with immunosuppressant activity Withdrawn EP0877554A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US818995P 1995-10-31 1995-10-31
US816995P 1995-10-31 1995-10-31
US8189P 1995-10-31
US8169P 1995-10-31
GBGB9603833.6A GB9603833D0 (en) 1996-02-23 1996-02-23 Triterpene derivatives with immunosuppressive activity
GB9603833 1996-02-23
GB9605156 1996-03-12
GBGB9605156.0A GB9605156D0 (en) 1996-03-12 1996-03-12 Triterpene derivatives with immunosuppressant activity
PCT/US1996/017211 WO1997016068A1 (en) 1995-10-31 1996-10-28 Triterpene derivatives with immunosuppressant activity

Publications (2)

Publication Number Publication Date
EP0877554A1 EP0877554A1 (en) 1998-11-18
EP0877554A4 true EP0877554A4 (ja) 1998-12-02

Family

ID=27451409

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96937010A Withdrawn EP0877554A1 (en) 1995-10-31 1996-10-28 Triterpene derivatives with immunosuppressant activity

Country Status (4)

Country Link
EP (1) EP0877554A1 (ja)
JP (1) JPH11514648A (ja)
AU (1) AU712015B2 (ja)
WO (1) WO1997016068A1 (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998408A (en) * 1996-10-16 1999-12-07 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
US5952371A (en) * 1996-10-16 1999-09-14 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
US5874594A (en) * 1996-10-16 1999-02-23 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
US6083980A (en) * 1997-10-17 2000-07-04 Merck & Co., Inc. Furanyl, tetracyclic triterpene derivatives with immunosuppressant activity
US6100293A (en) * 1997-10-17 2000-08-08 Merck & Co., Inc. Tetracyclic triterpene derivatives with immunosuppressant activity
US6022890A (en) * 1997-11-14 2000-02-08 Merck & Co., Inc. Immunosuppressant tetracyclic triterpenes
US6051590A (en) * 1999-05-13 2000-04-18 Merck & Co., Inc. Immunosuppressant tricyclic compounds
PT1539157E (pt) 2002-09-18 2013-10-04 Univ Pennsylvania Rapamicina para utilização na inibição ou prevenção de neovascularização coroidal
EP1639121A4 (en) * 2003-06-30 2008-04-16 Idenix Cayman Ltd SYNTHESIS OF BETA-L-2-DESOXYNUCLEOSIDES
EP1768662A2 (en) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
BRPI0608152A2 (pt) 2005-02-09 2009-11-10 Macusight Inc formulações para tratamento ocular
WO2007092620A2 (en) 2006-02-09 2007-08-16 Macusight, Inc. Stable formulations, and methods of their preparation and use
CA2645488C (en) 2006-03-23 2014-09-02 Macusight, Inc. Formulations comprising rapamycin and methods using same for vascular permeability-related diseases or conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997016438A1 (en) * 1995-10-31 1997-05-09 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
WO1997016182A1 (en) * 1995-10-31 1997-05-09 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3483191A (en) * 1963-09-13 1969-12-09 Squibb & Sons Inc Steroids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997016438A1 (en) * 1995-10-31 1997-05-09 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
WO1997016182A1 (en) * 1995-10-31 1997-05-09 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANAIS ASSOC. QUIM. BRASIL, vol. 5, no. 2, 1946, pages 39 - 42 *
CHEMICAL ABSTRACTS, vol. 41, no. 10, 20 May 1947, Columbus, Ohio, US; abstract no. 3109a, O. RIBEIRO ET AL: "Lophanterine, a new alkaloid" XP002077672 *
See also references of WO9716068A1 *

Also Published As

Publication number Publication date
EP0877554A1 (en) 1998-11-18
AU712015B2 (en) 1999-10-28
JPH11514648A (ja) 1999-12-14
WO1997016068A1 (en) 1997-05-09
AU7478196A (en) 1997-05-22

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19980602

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 19981020

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

17Q First examination report despatched

Effective date: 19990714

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20000127