EP0858340A4 - Kombinationstherapie zur behandlung des diabetes und der obesität - Google Patents
Kombinationstherapie zur behandlung des diabetes und der obesitätInfo
- Publication number
- EP0858340A4 EP0858340A4 EP96937097A EP96937097A EP0858340A4 EP 0858340 A4 EP0858340 A4 EP 0858340A4 EP 96937097 A EP96937097 A EP 96937097A EP 96937097 A EP96937097 A EP 96937097A EP 0858340 A4 EP0858340 A4 EP 0858340A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- obesity
- diabetes
- treatment
- combination therapy
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2264—Obesity-gene products, e.g. leptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US713895P | 1995-11-01 | 1995-11-01 | |
US7138P | 1995-11-01 | ||
GBGB9603724.7A GB9603724D0 (en) | 1996-02-22 | 1996-02-22 | Combinatyion therapy for the treatment of diabebes and obesity |
GB9603724 | 1996-02-22 | ||
PCT/US1996/017444 WO1997016189A1 (en) | 1995-11-01 | 1996-10-31 | Combination therapy for the treatment of diabetes and obesity |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0858340A1 EP0858340A1 (de) | 1998-08-19 |
EP0858340A4 true EP0858340A4 (de) | 1999-12-29 |
Family
ID=26308780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96937097A Withdrawn EP0858340A4 (de) | 1995-11-01 | 1996-10-31 | Kombinationstherapie zur behandlung des diabetes und der obesität |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0858340A4 (de) |
JP (1) | JPH11515027A (de) |
AU (1) | AU7484596A (de) |
WO (1) | WO1997016189A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6001968A (en) | 1994-08-17 | 1999-12-14 | The Rockefeller University | OB polypeptides, modified forms and compositions |
JP2000504318A (ja) * | 1996-01-19 | 2000-04-11 | イーライ・リリー・アンド・カンパニー | 肥満症タンパク質製剤 |
JP2001501177A (ja) * | 1996-08-30 | 2001-01-30 | アムジエン・インコーポレーテツド | Obタンパク質受容体をアップレギュレートすることによりobタンパク質に対する個体の感受性を増加させる方法 |
EP0969852A4 (de) * | 1996-10-31 | 2004-05-06 | Merck & Co Inc | Kombinationstherapie zur behandlung von diabetes und fettsucht |
EP0920864A1 (de) * | 1997-12-03 | 1999-06-09 | Pfizer Products Inc. | Kombinationstherapie durch einen spezifischen beta-3 Agonisten und einen Appetithemmer |
CA2362070A1 (en) * | 1999-02-16 | 2000-08-24 | Masaru Mitsuda | Substituted acetylpyridine derivatives and process for the preparation of intermediates for optically active .beta.3 agonist by the use of the same |
JP2004331500A (ja) * | 2001-02-16 | 2004-11-25 | Dainippon Pharmaceut Co Ltd | 血中濃度制御製剤 |
EP1454899A1 (de) * | 2001-10-17 | 2004-09-08 | Kaneka Corporation | Verfahren zur herstellung von (s)-alpha-halogenmethylpyridin methanol derivaten |
DE60334787D1 (de) | 2002-03-12 | 2010-12-16 | Merck Sharp & Dohme | Substituierte amide |
GB0718415D0 (en) | 2007-09-20 | 2007-10-31 | Glaxo Group Ltd | Compounds |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0611003A1 (de) * | 1993-02-09 | 1994-08-17 | Merck & Co. Inc. | Substituierte Phenylsulfonamine als selektive B3-Agonisten zur Behandlung von Diabetes und Fettleibigkeit |
WO1995029159A1 (en) * | 1994-04-26 | 1995-11-02 | Merck & Co., Inc. | SUBSTITUTED SULFONAMIDES AS SELECTIVE β3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY |
EP0920864A1 (de) * | 1997-12-03 | 1999-06-09 | Pfizer Products Inc. | Kombinationstherapie durch einen spezifischen beta-3 Agonisten und einen Appetithemmer |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
-
1996
- 1996-10-31 EP EP96937097A patent/EP0858340A4/de not_active Withdrawn
- 1996-10-31 AU AU74845/96A patent/AU7484596A/en not_active Abandoned
- 1996-10-31 JP JP9517529A patent/JPH11515027A/ja active Pending
- 1996-10-31 WO PCT/US1996/017444 patent/WO1997016189A1/en not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0611003A1 (de) * | 1993-02-09 | 1994-08-17 | Merck & Co. Inc. | Substituierte Phenylsulfonamine als selektive B3-Agonisten zur Behandlung von Diabetes und Fettleibigkeit |
WO1995029159A1 (en) * | 1994-04-26 | 1995-11-02 | Merck & Co., Inc. | SUBSTITUTED SULFONAMIDES AS SELECTIVE β3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY |
EP0920864A1 (de) * | 1997-12-03 | 1999-06-09 | Pfizer Products Inc. | Kombinationstherapie durch einen spezifischen beta-3 Agonisten und einen Appetithemmer |
Non-Patent Citations (1)
Title |
---|
See also references of WO9716189A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0858340A1 (de) | 1998-08-19 |
JPH11515027A (ja) | 1999-12-21 |
WO1997016189A1 (en) | 1997-05-09 |
AU7484596A (en) | 1997-05-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980602 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19991115 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 6A 61K 31/44 A, 6A 61K 38/18 B, 6A 61K 38/17 B, 6A 61K 38/22 B |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20010501 |