EP0851765A4 - Therapeutische und prophylaktische verfahren, welche hitzeschock-proteine einsetzen - Google Patents
Therapeutische und prophylaktische verfahren, welche hitzeschock-proteine einsetzenInfo
- Publication number
- EP0851765A4 EP0851765A4 EP96930818A EP96930818A EP0851765A4 EP 0851765 A4 EP0851765 A4 EP 0851765A4 EP 96930818 A EP96930818 A EP 96930818A EP 96930818 A EP96930818 A EP 96930818A EP 0851765 A4 EP0851765 A4 EP 0851765A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- therapeutic
- heat shock
- shock proteins
- prophylactic methods
- prophylactic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 102000002812 Heat-Shock Proteins Human genes 0.000 title 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 title 1
- 230000000069 prophylactic effect Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001176—Heat shock proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US527547 | 1995-09-13 | ||
US08/527,547 US5935576A (en) | 1995-09-13 | 1995-09-13 | Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens |
US711918 | 1996-09-10 | ||
US08/711,918 US6030618A (en) | 1995-09-13 | 1996-09-10 | Therapeutic and prophylactic methods using heat shock proteins |
PCT/US1996/014556 WO1997010000A1 (en) | 1995-09-13 | 1996-09-11 | Therapeutic and prophylactic methods using heat shock proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0851765A1 EP0851765A1 (de) | 1998-07-08 |
EP0851765A4 true EP0851765A4 (de) | 2000-01-19 |
Family
ID=27062437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96930818A Ceased EP0851765A4 (de) | 1995-09-13 | 1996-09-11 | Therapeutische und prophylaktische verfahren, welche hitzeschock-proteine einsetzen |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0851765A4 (de) |
JP (1) | JPH11513369A (de) |
AU (1) | AU727673B2 (de) |
CA (1) | CA2231998A1 (de) |
WO (1) | WO1997010000A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6773707B1 (en) | 1995-08-18 | 2004-08-10 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
US6331299B1 (en) | 1995-08-18 | 2001-12-18 | Sloan-Kettering Institute For Cancer Research | Method for treatment of cancer and infectious disease and compositions useful in same |
US6719974B1 (en) | 1995-08-18 | 2004-04-13 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
CA2229595A1 (en) | 1995-08-18 | 1997-02-27 | Sloan-Kettering Institute For Cancer Research | Method for treatment of cancer and infectious diseases and compositions useful in same |
US6761892B1 (en) | 1995-08-18 | 2004-07-13 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
US6017540A (en) * | 1997-02-07 | 2000-01-25 | Fordham University | Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes |
AU2005201826B2 (en) * | 1997-08-05 | 2008-01-17 | Nventa Biopharmaceuticals Corporation | Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins |
JP4198315B2 (ja) | 1997-08-05 | 2008-12-17 | ヌベンタ バイオファーマスティカル コーポレイション | Hpv抗原およびストレスタンパク質またはこれらのタンパク質の発現が可能な発現ベクターを含む組成物によって誘起されるhpv抗原に対する免疫応答 |
DK1336621T3 (da) * | 1997-08-05 | 2006-07-31 | Stressgen Biotechnologies Corp | Immunsvar mod HPV-antigener fremkaldt af sammensætninger, som omfatter et HPV-antigen og et stressprotein eller en ekspressionsvektor i stand til at eksprimere disse proteiner |
US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
ES2439014T3 (es) | 1998-02-20 | 2014-01-21 | The University Of Miami | Complejo de péptido antigénico-proteína de choque térmico modificada |
US6797480B1 (en) | 1998-10-05 | 2004-09-28 | University Of Connecticut Health Center | Purification of heat shock/stress protein cell surface receptors and their use as immunotherapeutic agents |
AUPQ233799A0 (en) | 1999-08-19 | 1999-09-09 | Minister For Agriculture, Minister For Land And Water Conservation For And On Behalf Of The State Of New South Wales | Recombinant sub-unit vaccine |
GB9919733D0 (en) * | 1999-08-19 | 1999-10-20 | Colaco Camilo | Vaccines against intracellular pathogens |
WO2001023421A2 (en) | 1999-09-30 | 2001-04-05 | Corixa Corporation | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease |
US7378096B2 (en) | 1999-09-30 | 2008-05-27 | Health Research, Inc. | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease |
US7030228B1 (en) | 1999-11-15 | 2006-04-18 | Miltenyi Biotec Gmbh | Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby |
US7449557B2 (en) | 2000-06-02 | 2008-11-11 | University Of Connecticut Health Center | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy |
KR20040064688A (ko) | 2001-08-20 | 2004-07-19 | 유니버시티 오브 코네티컷 헬스 센터 | 암 또는 전염병 치료에 유용한 열 충격 단백질 또는알파-2-마크로글로불린을 포함하는 조성물 제조 방법 |
US7691969B2 (en) | 2001-10-01 | 2010-04-06 | Duke University | Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, crystalline form of same, and screening methods employing same |
AU2003231098A1 (en) * | 2002-04-25 | 2003-11-10 | University Of Connecticut Health Center | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
US7420037B2 (en) | 2003-02-13 | 2008-09-02 | Antigenics Inc. | Heat shock protein-based vaccines and immunotherapies |
ATE491463T1 (de) | 2003-02-20 | 2011-01-15 | Univ Connecticut Health Ct | Verfahren zur herstellung von alpha (2) makroglobulin-antigen-molekül-komplexen |
KR20060026004A (ko) | 2003-02-28 | 2006-03-22 | 안티제닉스 아이엔씨 | 당단백질 및 항원성 분자의 올리고머화를 조장하는 렉틴의용도 |
US7309491B2 (en) | 2003-04-11 | 2007-12-18 | Antigenics Inc. | Heat shock protein-based vaccines and immunotherapies |
JP2007505147A (ja) * | 2003-09-12 | 2007-03-08 | アンティジェニクス インコーポレーテッド | 単純ヘルペスウイルス感染の治療および予防用ワクチン |
WO2009114085A2 (en) | 2008-03-03 | 2009-09-17 | The University Of Miami | Allogeneic cancer cell-based immunotherapy |
JP2011515399A (ja) | 2008-03-20 | 2011-05-19 | ユニバーシティー オブ マイアミ | 熱ショックタンパクgp96ワクチン接種及びそれを用いた方法 |
CA2757524A1 (en) | 2009-04-03 | 2010-10-07 | Agenus Inc. | Methods for preparing and using multichaperone-antigen complexes |
GB0910591D0 (en) * | 2009-06-19 | 2009-07-29 | Immunobiology Ltd | Method for the purification of protein complexes |
GB0916557D0 (en) | 2009-09-21 | 2009-10-28 | Health Prot Agency | Commensal neisserial stress protein complexes |
AU2016215175B2 (en) | 2015-02-06 | 2021-09-16 | Heat Biologics, Inc. | Vector co-expressing vaccine and costimulatory molecules |
CA2984643A1 (en) | 2015-05-13 | 2016-11-17 | Agenus Inc. | Vaccines for treatment and prevention of cancer |
US11666649B2 (en) | 2016-10-11 | 2023-06-06 | University Of Miami | Vectors and vaccine cells for immunity against Zika virus |
WO2018187260A1 (en) | 2017-04-04 | 2018-10-11 | Heat Biologics, Inc. | Intratumoral vaccination |
EP3784688A2 (de) | 2018-04-26 | 2021-03-03 | Agenus Inc. | Hitzeschockproteinbindende peptidzusammensetzungen und verfahren zu deren verwendung |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993017712A2 (en) * | 1992-03-06 | 1993-09-16 | Biocine Spa | Conjugates formed from heat shock proteins and oligo- or polysaccharides |
WO1994003208A1 (en) * | 1992-07-30 | 1994-02-17 | Yeda Research And Development Company Ltd. | Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989012455A1 (en) * | 1988-06-15 | 1989-12-28 | Whitehead Institute For Biomedical Research | Stress proteins and uses therefor |
-
1996
- 1996-09-11 CA CA002231998A patent/CA2231998A1/en not_active Abandoned
- 1996-09-11 WO PCT/US1996/014556 patent/WO1997010000A1/en active Application Filing
- 1996-09-11 EP EP96930818A patent/EP0851765A4/de not_active Ceased
- 1996-09-11 AU AU69734/96A patent/AU727673B2/en not_active Ceased
- 1996-09-11 JP JP9512062A patent/JPH11513369A/ja not_active Ceased
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993017712A2 (en) * | 1992-03-06 | 1993-09-16 | Biocine Spa | Conjugates formed from heat shock proteins and oligo- or polysaccharides |
WO1994003208A1 (en) * | 1992-07-30 | 1994-02-17 | Yeda Research And Development Company Ltd. | Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them |
Non-Patent Citations (2)
Title |
---|
P. K. SRIVASTAVA ET AL.: "Heat shock protein-peptide complexes in cancer immunotherapy", CURRENT OPINION IN IMMUNOLOGY, vol. 6, 1994, pages 728 - 732, XP002037578 * |
See also references of WO9710000A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0851765A1 (de) | 1998-07-08 |
CA2231998A1 (en) | 1997-03-20 |
JPH11513369A (ja) | 1999-11-16 |
AU727673B2 (en) | 2000-12-21 |
AU6973496A (en) | 1997-04-01 |
WO1997010000A1 (en) | 1997-03-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980409 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19991208 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 19991208 |
|
17Q | First examination report despatched |
Effective date: 20010326 |
|
17Q | First examination report despatched |
Effective date: 20010326 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 20080219 |