EP0838203B1 - Implant to medialize vocal cords - Google Patents
Implant to medialize vocal cords Download PDFInfo
- Publication number
- EP0838203B1 EP0838203B1 EP97115386A EP97115386A EP0838203B1 EP 0838203 B1 EP0838203 B1 EP 0838203B1 EP 97115386 A EP97115386 A EP 97115386A EP 97115386 A EP97115386 A EP 97115386A EP 0838203 B1 EP0838203 B1 EP 0838203B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- implant
- thyroid cartilage
- vocal
- bend
- medialize
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/06—Titanium or titanium alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/20—Epiglottis; Larynxes; Tracheae combined with larynxes or for use therewith
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
Definitions
- the invention relates to an implant for medialization of the Vocal cords according to the preamble of claim 1, as is known for example from US-A-5 197 982.
- These implants are used for paralysis of the vocal fold narrow the glottis and the vocal folds out to bring them back to the midline in their lateral position.
- an opening is made in the thyroid cartilage, through which the implant is inserted and thereby the vocal fold is medialized.
- a disadvantage of the so far mainly The implants used is that there are certain objections to this used material exist. These implants must be dated Surgeons are cut out of a silicone block. The Application is therefore time-consuming and the design is successful not always optimal.
- the fixation of the implants difficult, so that a shift is possible.
- Such Displacement of the implants z. B. inside the larynx can have life-threatening consequences as it causes breathing is relocated.
- the object of the present invention is an implant to create that with a standardized technique during surgery under local anesthesia of the patient can be used quickly and safely, the degree of Medialization is individually adjustable.
- the task is carried out with an implant of the type mentioned at the beginning Art solved according to the invention in that between the middle part and at least one of the hook-shaped End regions a bend of the metal strip is arranged, that after inserting the implant between the thyroid cartilage and the vocal fold lies.
- the contact pressure can also be used also vary in a smaller range in that the entire implant changed in its distance from the vocal fold becomes.
- the implant can either be made from a body-compatible body Made of metal and / or with a body-compatible Be covered. Coming as material for the implant for example titanium sheet or also gold or stainless steel sheet in question.
- a particular advantage of the present invention is that The implant is secure after insertion into the thyroid cartilage can be positioned so that a displacement of the implant, possibly even in the airways with life-threatening Complications, is not possible. This is due to the special Shaping the implant and bending the metal ends achieved, and can be achieved by fixing the implant further secured with a set screw on the thyroid cartilage become.
- the only figure shows a partial section through the human Larynx. It is the one located in the anterior larynx area To recognize thyroid cartilage 10 from which itself Vocal folds 11 to cartilage 20 not shown extend. There is an opening in the side of the thyroid cartilage 10 12 has been introduced through which an implant 13 for one of the two vocal folds 11 is inserted.
- the implant 13 is indicated in the figure by a thick black line and bent from a metal strip. It points a middle part 14 which bears against the vocal fold 11.
- the end regions 15 and 16 of the implant 13 are hook-shaped trained and embrace the edges of the opening 12 in the thyroid cartilage 10. Between the middle part 14 and the lower hook-shaped End region 16 of implant 13 is a bend 17 of the metal strip arranged.
- This bend 17 is between the thyroid cartilage 10 and the vocal fold 11 and generated thus a bias of the middle part 14 against the vocal fold 11.
- the degree of preload can be changed by changing the Radius of the bend 17 can be varied, indicated by a double arrow 18 is indicated. Also a shift in the middle section 14 in the direction of the vocal fold 11 leads to a Increasing the preload of the middle part 14.
- This shift can be made by means of a set screw 19, with which the end region 15 of the implant 13 with the thyroid cartilage 10 is connected.
- the bias of the middle part 14 against the vocal fold 11 either by bending or compressing the bend 17 or by adjusting the screw 19 during the Operation of the patient under local anesthesia become. According to the result of being constantly with the patient feasible voice tests can thus be an optimal Preloading the implant 13 and thus optimal support achieve the vocal fold 11.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Description
Die Erfindung betrifft ein Implantat zur Medialisation der Stimmlippen gemäß dem Oberbegriff des Anspruchs 1, wie es beispielsweise aus US-A-5 197 982 bekannt ist. Diese Implantate dienen dazu, bei einer Stimmlippenlähmung die Stimmritze zu verengen und die Stimmlippen aus ihrer Lateralstellung wieder in die Mittellinie zu bringen. Hierzu wird in den Schildknorpel eine Öffnung eingebracht, durch die das Implantat eingesetzt und dadurch die Stimmlippe medialisiert wird. Nachteilig bei den bisher hauptsächlich verwendeten Implantaten ist, daß gewisse Einwände gegen das eingesetzte Material bestehen. Diese Implantate müssen vom Chirurgen aus einem Silikonblock herausgeschnitten werden. Die Anwendung ist somit zeitraubend und die Formgebung gelingt nicht immer optimal. Außerdem ist die Fixierung der Implantate schwierig, so daß eine Verschiebung möglich ist. Eine solche Verschiebung der Implantate z. B. in das Innere des Kehlkopfes kann lebensgefährliche Folgen haben, da dadurch die Atmung verlegt wird.The invention relates to an implant for medialization of the Vocal cords according to the preamble of claim 1, as is known for example from US-A-5 197 982. These implants are used for paralysis of the vocal fold narrow the glottis and the vocal folds out to bring them back to the midline in their lateral position. For this purpose, an opening is made in the thyroid cartilage, through which the implant is inserted and thereby the vocal fold is medialized. A disadvantage of the so far mainly The implants used is that there are certain objections to this used material exist. These implants must be dated Surgeons are cut out of a silicone block. The Application is therefore time-consuming and the design is successful not always optimal. In addition, the fixation of the implants difficult, so that a shift is possible. Such Displacement of the implants z. B. inside the larynx can have life-threatening consequences as it causes breathing is relocated.
Der vorliegenden Erfindung liegt die Aufgabe zugrunde, ein Implantat zu schaffen, das mit einer standardisierten Technik während der Operation unter lokaler Anästhesie des Patienten rasch und sicher eingesetzt werden kann, wobei der Grad der Medialisierung individuell einstellbar ist. The object of the present invention is an implant to create that with a standardized technique during surgery under local anesthesia of the patient can be used quickly and safely, the degree of Medialization is individually adjustable.
Die Aufgabe wird mit einem Implantat der eingangs genannten Art erfindungsgemäß dadurch gelöst, daß zwischen dem Mittelteil und mindestens einem der hakenförmigen Endbereiche eine Biegung des Metallstreifens angeordnet ist, die nach dem Einsetzen des Implantates zwischen dem Schildknorpel und der Stimmlippe liegt. Durch Veränderung des Radius dieser Biegung läßt sich der Anpreßdruck des Mittelteils gegen die Stimmlippe variieren. Weiter läßt sich der Anpreßdruck auch dadurch in einem kleineren Bereich variieren, daß das gesamte Implantat in seinem Abstand zur Stimmlippe verändert wird. Um diese Art der Einstellung des Anpreßdruckes des Implantates zu ermöglichen, kann mindestens einer der hakenförmigen Endbereiche mittels einer Stellschraube am Schildknorpel befestigbar sein. Zur Vermeidung von Abstoßungsreaktionen des Körpers kann das Implantat entweder aus einem körperverträglichen Metall gefertigt und/oder mit einem körperverträglichen Überzug versehen sein. Als Material für das Implantat kommen beispielsweise Titanblech oder aber auch Gold- oder Edelstahlblech in Frage.The task is carried out with an implant of the type mentioned at the beginning Art solved according to the invention in that between the middle part and at least one of the hook-shaped End regions a bend of the metal strip is arranged, that after inserting the implant between the thyroid cartilage and the vocal fold lies. By changing the radius the contact pressure of the middle part can be countered by this bend the vocal fold vary. The contact pressure can also be used also vary in a smaller range in that the entire implant changed in its distance from the vocal fold becomes. About this type of setting the contact pressure of the implant to enable at least one of the hook-shaped End areas using a set screw on the thyroid cartilage be attachable. To avoid rejection reactions of the The implant can either be made from a body-compatible body Made of metal and / or with a body-compatible Be covered. Coming as material for the implant for example titanium sheet or also gold or stainless steel sheet in question.
Ein spezieller Vorteil der vorliegenden Erfindung ist, daß das Implantat nach seinem Einsetzen in den Schildknorpel sicher positioniert werden kann, so daß eine Verschiebung des Implantates, eventuell sogar in die Luftwege mit lebensbedrohlichen Komplikationen, nicht möglich ist. Dies wird durch die spezielle Formgebung des Implantates und das Umbiegen der Metallenden erreicht, und kann durch die Fixierung des Implantates mittels einer Stellschraube am Schildknorpel noch weiter abgesichert werden. A particular advantage of the present invention is that The implant is secure after insertion into the thyroid cartilage can be positioned so that a displacement of the implant, possibly even in the airways with life-threatening Complications, is not possible. This is due to the special Shaping the implant and bending the metal ends achieved, and can be achieved by fixing the implant further secured with a set screw on the thyroid cartilage become.
Nachfolgend wird ein bevorzugtes Ausführungsbeispiel eines erfindungsgemäßen Implantates anhand der Zeichnung näher erläutert.A preferred embodiment of a implant according to the invention explained in more detail with reference to the drawing.
Die einzige Figur zeigt einen Teilschnitt durch den menschlichen
Kehlkopf. Es ist der im vorderen Kehlkopfbereich angeordnete
Schildknorpel 10 zu erkennen, von den aus sich
Stimmlippen 11 zu nicht näher dargestellten Stellknorpeln 20
erstrecken. In dem Schildknorpel 10 ist seitlich eine Öffnung
12 eingebracht worden, durch die ein Implantat 13 für
eine der beiden Stimmlippen 11 eingesetzt ist. Das Implantat
13 ist in der Figur durch eine dicke schwarze Linie gekennzeichnet
und aus einem Metallstreifen gebogen. Es weist
einen Mittelteil 14 auf, der gegen die Stimmlippe 11 anliegt.
Die Endbereiche 15 und 16 des Implantates 13 sind hakenförmig
ausgebildet und umgreifen die Ränder der Öffnung 12 im Schildknorpel
10. Zwischen dem Mittelteil 14 und dem unteren hakenförmigen
Endbereich 16 des Implantates 13 ist eine Biegung 17
des Metallstreifens angeordnet. Diese Biegung 17 liegt zwischen
dem Schildknorpel 10 und der Stimmlippe 11 und erzeugt
somit eine Vorspannung des Mittelteils 14 gegen die Stimmlippe
11. Der Grad der Vorspannung kann durch Veränderung des
Radius der Biegung 17 variiert werden, was durch einen Doppelpfeil
18 angedeutet ist. Auch eine Verschiebung des Mittelteils
14 in Richtung auf die Stimmlippe 11 führt zu einer
Erhöhung der Vorspannung des Mittelteils 14. Diese Verschiebung
kann mittels einer Stellschraube 19 vorgenommen werden,
mit der der Endbereich 15 des Implantates 13 mit dem Schildknorpel
10 verbunden ist. Bei dem dargestellten Implantat kann
also die Vorspannung des Mittelteils 14 gegen die Stimmlippe
11 entweder durch Aufbiegen oder Zusammendrücken der Biegung
17 oder durch Verstellen der Schraube 19 während der
Operation des Patienten unter lokaler Anästhesie vorgenommen
werden. Entsprechend dem Ergebnis der ständig mit dem Patienten
durchführbaren Stimmtests läßt sich somit eine optimale
Vorspannung des Implantates 13 und somit eine optimale Unterstützung
der Stimmlippe 11 erzielen.The only figure shows a partial section through the human
Larynx. It is the one located in the anterior larynx area
To recognize
Claims (4)
- Implant to medialise vocal cords, in particular after vocal cord paralysis, which can be inserted into a surgically-formed opening in the thyroid cartilage, the implant having a bent element made of a meta strip having a central part (14) which can be placed against the vocal cord and hooked end portions (15,16) encompassing the edges of the opening in the thyroid cartilage (12), characterised in that a bend (17) is arranged between central part (14) and at least one of the hooked end portiors (16) of the metal strip, which bend (17) is located between the thyroid cartilage (10) and the vocal cord (11) after insertion of the implant (13).
- Implant according to Claim 1, characterised in that at least one of the hooked end portions (15,16) is fixable to the thyroid cartlage (10) by means of an adjusting screw (19).
- Implant according to Claim 1 or 2, characterised in that it is made of a body-compatible material and/or is provided with a body-compatible sheath.
- Implant according to one of Claims 1 to 3, characterised in that it is made of titanium sheet.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE29616828U | 1996-09-27 | ||
| DE29616828U DE29616828U1 (en) | 1996-09-27 | 1996-09-27 | Implant for medialization of the vocal folds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0838203A1 EP0838203A1 (en) | 1998-04-29 |
| EP0838203B1 true EP0838203B1 (en) | 2001-11-28 |
Family
ID=8029806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP97115386A Expired - Lifetime EP0838203B1 (en) | 1996-09-27 | 1997-09-05 | Implant to medialize vocal cords |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US5855607A (en) |
| EP (1) | EP0838203B1 (en) |
| DE (2) | DE29616828U1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010111140A2 (en) * | 2009-03-25 | 2010-09-30 | University Of Iowa Research Foundation | Methods and devices for arytenoid repositioning |
| US8613767B2 (en) | 2010-12-13 | 2013-12-24 | Wisconsin Alumni Research Foundation | Laryngeal implant for treating glottic insufficiency |
| US9277913B2 (en) * | 2012-04-18 | 2016-03-08 | Timothy M. McCulloch | Devices and methods for anterior arytenoid adduction |
| EP2700384B1 (en) | 2012-08-24 | 2018-01-17 | Cook Medical Technologies LLC | Medical devices and systems for medialization of a vocal cord |
| US9433499B2 (en) | 2013-05-07 | 2016-09-06 | Cook Medical Technologies Llc | Vocal cord medialization |
| WO2015111340A1 (en) * | 2014-01-27 | 2015-07-30 | 学校法人東邦大学 | Dysphonia treatment implement |
| ES2919227T3 (en) * | 2015-08-10 | 2022-07-22 | Nobelpharma Co Ltd | Voice disorders treatment tool |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2047376T3 (en) * | 1990-04-20 | 1994-02-16 | Smith & Nephew Richards Inc | FONOCIRUGIA INSTRUMENTAL. |
| US5344453A (en) * | 1991-05-30 | 1994-09-06 | Boston Medical Products, Inc. | Thyroplasty implant |
| US5201765A (en) * | 1991-09-20 | 1993-04-13 | Xomed-Treace Inc. | Vocal cord medialization prosthesis |
| US5197982A (en) * | 1991-10-15 | 1993-03-30 | Goldsmith Iii Manning M | Adjustable prosthetic device for vocal cord and method |
| US5306298A (en) * | 1993-02-16 | 1994-04-26 | Godley Iii Frederick A | Adjustable laryngoplasty device |
-
1996
- 1996-09-27 DE DE29616828U patent/DE29616828U1/en not_active Expired - Lifetime
-
1997
- 1997-09-05 DE DE59705529T patent/DE59705529D1/en not_active Expired - Lifetime
- 1997-09-05 EP EP97115386A patent/EP0838203B1/en not_active Expired - Lifetime
- 1997-09-26 US US08/938,201 patent/US5855607A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5855607A (en) | 1999-01-05 |
| DE59705529D1 (en) | 2002-01-10 |
| EP0838203A1 (en) | 1998-04-29 |
| DE29616828U1 (en) | 1996-12-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE19603285B4 (en) | Intramedullary nail | |
| DE69922075T2 (en) | Orthopedic bone plate | |
| DE69111329T2 (en) | Device for correcting scoliosis. | |
| DE60130317T2 (en) | CLAMP ATTACHING ARRANGEMENT FOR ATTACHING A SURGICAL CLIP TO BODY TISSUE | |
| EP1287787B1 (en) | Implant for the fixation of bone fractures | |
| DE3021238A1 (en) | ARRANGEMENT WITH HOOK-SHAPED ELEMENTS | |
| EP1152703B1 (en) | Implant for fixing a bone plate | |
| EP0809982B1 (en) | Stapedial prosthesis for implantation in the middle ear | |
| EP0689798A1 (en) | Connecting member to connect an elastic rod with a spinal pedicle screw | |
| DE3900738C2 (en) | ||
| DD142843A5 (en) | DEVICE FOR TREATING BACKGRADE CLEARANCE | |
| DE10159181A1 (en) | Surgical auxiliary instrument | |
| DE4127550A1 (en) | Implantable surgical connecting plate - is used for attaching strap to bone and has two parallel slots to hold strap to plate | |
| EP1452148A2 (en) | Bracket | |
| WO2003068091A1 (en) | Bone plate | |
| DE60103380T2 (en) | SURGEONIC SURGERY | |
| AT395940B (en) | BONE NAIL AND TOOL FOR THE SAME | |
| EP0838203B1 (en) | Implant to medialize vocal cords | |
| EP1624831A1 (en) | Device for implanting in a human or animal vertebral column | |
| EP1744698A1 (en) | Orthodontic bracket | |
| DE29908794U1 (en) | Cannula, especially for insertion into the spinal canal | |
| DE2459257C3 (en) | Curved elastic bone nail for fixing bridges in the proximal thigh area | |
| DE29718091U1 (en) | Ear prosthesis | |
| DE29903131U1 (en) | Implant to fix a bone plate | |
| WO2024067949A1 (en) | Retractor for surgical operations, and retractor system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): DE FR GB NL |
|
| 17P | Request for examination filed |
Effective date: 19981009 |
|
| AKX | Designation fees paid |
Free format text: DE FR GB NL |
|
| RBV | Designated contracting states (corrected) |
Designated state(s): DE FR GB NL |
|
| GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
| GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
| GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
| 17Q | First examination report despatched |
Effective date: 20010425 |
|
| GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
| GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
| AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): DE FR GB NL |
|
| REG | Reference to a national code |
Ref country code: GB Ref legal event code: IF02 |
|
| REF | Corresponds to: |
Ref document number: 59705529 Country of ref document: DE Date of ref document: 20020110 |
|
| GBT | Gb: translation of ep patent filed (gb section 77(6)(a)/1977) |
Effective date: 20020207 |
|
| ET | Fr: translation filed | ||
| PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
| 26N | No opposition filed | ||
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 20090923 Year of fee payment: 13 Ref country code: GB Payment date: 20090820 Year of fee payment: 13 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20091016 Year of fee payment: 13 |
|
| REG | Reference to a national code |
Ref country code: NL Ref legal event code: V1 Effective date: 20110401 |
|
| GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20100905 |
|
| REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20110531 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100930 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100905 Ref country code: NL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20110401 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20160822 Year of fee payment: 20 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 59705529 Country of ref document: DE |