EP0756567B1 - Mit einer abgabevorrichtung versehener tablettenbehälter - Google Patents
Mit einer abgabevorrichtung versehener tablettenbehälter Download PDFInfo
- Publication number
- EP0756567B1 EP0756567B1 EP95916631A EP95916631A EP0756567B1 EP 0756567 B1 EP0756567 B1 EP 0756567B1 EP 95916631 A EP95916631 A EP 95916631A EP 95916631 A EP95916631 A EP 95916631A EP 0756567 B1 EP0756567 B1 EP 0756567B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- dispensing
- passage
- tablet
- dispensing opening
- opening
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
- B65D83/0481—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills the articles passing through a small opening or passage, without additional dispensing devices and without retaining means for the following article
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2583/00—Containers or packages with special means for dispensing contents
- B65D2583/04—For dispensing annular, disc-shaped or spherical or like small articles or tablets
- B65D2583/0431—Disc-like articles arranged in a pile on their flat side
Definitions
- This invention relates to a novel container for containing and dispensing tablets.
- This invention provides a container according to claim 1 which in part at least overcomes these disadvantages of known containers.
- Other objects and advantages of the invention will be apparent from the following description.
- the tablets which can be dispensed by the container of this invention may be pharmaceutical formulations, e.g. for oral administration directly or after dispersion or dissolution, confectionery, e.g. sweets, or other tablets.
- Shapes which are flattened about a plane include circular discs, oval discs, lozenge shapes, tetragonal shapes, parallelogram shapes, oblate spheroids etc.
- the plane may be a plane of symmetry of the tablet.
- a particular shape flattened about a plane is a circular disc, for example with beveled edges.
- the cross-sectional shape of the dispensing opening(s), about the dispensing direction is substantially a slot shape, suitably a rectangular slot shape, optionally with rounded corners or one or more rounded ends, e.g. a lozenge shape opening.
- the cross section of the dispensing opening may correspond in shape to the cross section of the tablet perpendicular to the plane about which it is flattened.
- the dispensing opening may be defined by a lip which is the downstream extremity of passage-forming walls which extend upstream from the dispensing opening to define a dispensing passage between passage-forming walls upstream of the dispensing opening.
- the passage-forming walls may taper, narrowing toward and to form a slot-shape dispensing opening. Such a tapering dispensing passage may assist in guiding and orienting tablets toward the dispensing opening.
- Such releasable retention of the tablet in the dispensing passage with part of the tablet projecting outside the dispensing opening provides the advantage that the retained tablet blocks the passage and prevents excess tablets from passing through the dispensing package, thereby preventing spillage of tablets. Additionally this releasable retention allows the user to grip the projecting part of the tablet and withdraw the entire tablet from the dispensing opening, without having to catch a falling or rolling tablet. This reduces the possibility of accidental dropping of the tablet.
- releasable retention it is meant that the tablet is retained in the dispensing opening against the forces urging the tablet in the dispensing direction during dispensing such as gravity or the weight of upstream tablets, but that an easy tug by the hand of a user can extract the tablet without inconvenient effort or damage to the tablet.
- the releasable retention of the tablet may be achieved by making the lip of the dispensing opening and/or an immediately upstream adjacent part of the dispensing passage resilient to a degree that the constriction can be easily urged apart by the act of extracting the tablet.
- the dispensing opening and/or immediately upstream adjacent part of the dispensing passage may be constricted by for example a narrowing of the opening and/or passage-forming walls relative to an upstream part of the dispensing passage, or by means of inwardly-extending projections, e.g. surface convexities, such as ridges, bumps, etc., or by a combination of two or more such types of constriction.
- Other methods of constricting the passage will be apparent to those skilled in the art.
- the constriction may provide a narrowing of the dispensing opening and/or the dispensing passage to slightly less than, e.g. 0.999 - 0.95, e.g. around 0.97 times, the width, e.g.
- diameter of a circular tablet and/or the thickness of a tablet.
- the exact degree of constriction and/or resilience necessary will depend upon the particular materials, size, thickness etc. of the passage forming walls and lip, and the shape, size and strength of the tablet, and can easily be determined by simple experimentation in a particular case.
- the constriction(s) should suitably be located at the dispensing opening, or, relative to the length of the dispensing passage, within one tablet width, or one diameter in the case of circular tablets, of the dispensing opening to ensure that part of the tablet projects from the dispensing opening.
- the constriction(s) may be located at in the vicinity of the dispensing opening, e.g. at the lip of the dispensing opening.
- the constriction(s) should have dimensions such that the tablet is releasable with relative ease from its retention in the dispensing opening, e.g. with gentle pulling, without damage to the tablet surface, but should not be so loosely retained that the tablet can fall under the action of gravity from the opening.
- the tablet may be releasably retained by making at least the lip of the dispensing opening, suitably also the passage forming walls, of thin resilient plastics material.
- the position and nature of the constriction is suitably such that half or less of the tablet projects from the dispensing opening when the tablet is retained in the dispensing opening.
- the amount of the tablet that needs to project to allow easy gripping and extraction will depend upon the tablet and can be easily determined.
- the dispenser may also include other features to make it more easy for the user to extract the retained tablet from the dispensing opening. For example there may be one or more cut-outs in the passage-defining walls, extending upstream from the dispensing opening, enabling the user to grip a larger surface area of the tablet. Two such cut-outs may be positioned on opposite sides of the dispensing passage. In an extreme form of such cut-outs one or more of the passage-forming walls may be completely absent immediately upstream of the dispensing opening.
- the container of the invention may include one or more such dispensing openings, for example two dispensing openings side-by-side, with respective dispensing passages.
- each such dispensing opening may be adapted to dispense tablets with the plane about which each is flattened aligned substantially parallel.
- pairs of such side-by-side dispensing openings may share a common slot-forming wall. If the container of the invention has two or more dispensing openings side by side the common slot forming wall may for example be in the form of a web dividing a larger opening into two side-by-side dispensing openings, and may be formed integrally or may be a separate part, e.g. retained by a snap-fit action.
- the overall container itself may be of any convenient shape.
- the container may suitably be of a shape that causes or encourages the user to align it in a preferred orientation relative to the plane about which the tablet is flattened, for example having a generally rectangular, triangular or oval cross-sectioned body.
- the storage compartment may be of any convenient shape which allows the tablets to freely flow towards the dispensing opening.
- the storage compartment may have a sectional shape which corresponds closely to the shape of the tablets contained within it, but with sufficient internal clearance between tablets and the internal face of the container wall to reduce the possibility of jamming of the tablets within the container during dispensing.
- a suitable storage compartment internal diameter is between D (the diameter of the tablet) and 1.05 times the diagonal of two stacked tablets, i.e. no more than 1.05 x the square root of [D 2 + (2T) 2 ].
- the internal diameter should suitably be no more than 25.4 mm, preferably less, e.g. 25.2 mm or less. Suitable internal dimensions may be determined by relatively straightforward experimentation for any particular application.
- the dispensing opening(s) and the passage-forming walls may for example be formed integrally with the overall container.
- the dispensing opening(s) and/or dispensing passage(s) and their respective forming walls may for example be formed separately in a separate adapter to be attached to the neck of a container body which comprises a storage compartment, to form a container of the invention.
- Such an adapter may for example include a compartment for a desiccant to protect the tablets within the container from atmospheric moisture, or an additional or alternative preservative.
- a compartment may conveniently be formed around the narrowing part of the dispensing passage.
- Such an adapter may be provided as a separate item to be attached to the mouth opening of a container body, and such an adapter forms a further aspect of this invention.
- the dispensing opening(s) of the container may conveniently be provided with closures which may be of an conventional known type, for example a hinged closure having a snap-fit closure action.
- the container may be made of plastics materials, for example by injection moulding.
- a circular tablet (1) is shown in perspective view, having a diameter D and a thickness T. This tablet (1) is flattened about the plane in which the diameter D lies.
- a container of the invention is shown in an exploded view in Fig 3, and in a sectional view in Fig 2, the upper part of the container, i.e. adjacent to the dispensing opening, being shown.
- the container comprises a cylindrical body (2), defining an internal storage compartment (3) which contains disc shaped tablets (1) of thickness T and diameter D, the diagonal of two stacked tablets (1) being Z.
- the internal diameter d of the storage compartment (3) is between D and 1.05 Z.
- an adapter (5 overall) made of a resilient and flexible plastics material, and which is a snap-fit into the open top (4) of the body (2).
- the adapter (5) comprises a shell wall (6) of a generally cylindrical shape conforming to the shape of the body (2), and with a profiled lower end (7) to form a snap-fit with a correspondingly profiled rim around the open top (4) of the body (2).
- Within the shell wall (6) are integral passage-forming walls (8) which define a dispensing passage (9) which tapers towards a dispensing opening (10) which is a rectangular slot shape with rounded ends, i.e. lozenge shaped.
- the passage-forming walls (8) terminate at and to define the lip of the opening (10), and the passage-forming walls (8) extend upstream from the lip of the dispensing opening (10).
- the passage (9) is of circular section, large enough for a tablet (1) to enter the passage (9) and pass along it during dispensing toward the dispensing opening (10).
- the length and width dimensions of the slot of the dispensing opening (10) are just sufficient to allow a tablet (1) to pass through with clearance.
- the diameter d of the body (2) reduces the possibility that tablets (1) will jam during dispensing.
- the tapering dispensing passage (9) guides and orients tablets (1) towards the dispensing opening (10).
- the dispensing opening (10) is closed by a snap fit cap (11) which fits over the entire mouth part.
- a flexible resilient plastics material fork (13) which holds the tablets (1) in place within the storage compartment (3) during storage.
- a desiccant material which helps to preserve the tablets (1).
- the desiccant material is held in place within the cavity (14) by means of covers (15) fitting into the upper part of the cavity. The covers (15) do not form an airtight seal over the top of the cavities (14) so that the desiccant in cavity (14) can exercise its desiccating effect in the interior of the storage compartment (3).
- FIG. 5 one form of the adapter (5) of the container of Figs 2 and 3 is shown in longitudinal section, cut through a longitudinal plane perpendicular to the paper of Fig 2, in Fig 5A, and in cross section about the line A-A of Fig 5A in Fig 5B. Parts corresponding to Figs 2 and 3 are numbered correspondingly.
- the dispensing passage (9) is constricted by narrowing the dispensing passage (9) across the width of the tablet (1) immediately upstream of the dispensing opening (10), to slightly less than the diameter D of the tablet (1), so that as a tablet (1) passes along the dispensing passage (9) from the interior of the container, the tablet (1) is retained and caught at (16) across its width within the dispensing passage (9) with part of the tablet (1) projecting outside the dispensing opening (10).
- FIG 6 another form of the adapter (5) of the container of Figs 2 and 3 is shown in longitudinal sectional view, cut through a longitudinal plane being that of the paper of Fig 2, in Fig 6A, and in cross sectional view in Fig 6B.
- Fig 6A also corresponds to a sectional view through the line B-B of Fig 6B. Parts corresponding to Figs 2 and 3 are numbered correspondingly.
- the dispensing passage (9) is constricted by the provision of small inward projections (17) immediately upstream of the dispensing opening (10), the distance between opposing pairs of projections (17) being slightly less than the thickness T of the tablet (1), so that as a tablet (1) passes along the dispensing passage (9) from the interior of the container, the tablet (1) is retained and caught across its thickness within the dispensing passage (9) with part of the tablet (1) projecting outside the dispensing opening (10).
- the projections (17) are shown in Fig 6 as small rounded bumps, but they could be any convenient shape, e.g. conical or ridges etc.
- the adapter (5) can be constricted both by the narrowing described above with respect to Fig 5 and by inward projections (17).
- the dispensing passage (9) may simply be narrowed in the plane of Fig 6A so that tablets (1) are caught across their thickness, or the dispensing passage (9) may be provided with convexities that project inwardly in the plane of the width of the tablets (1) so that they are caught across their thickness between these projections.
- only one wall (8) need be provided with projections (17) so that a tablet (1) is caught between the projection(s) (17) and the opposite wall (8).
- the retention of the tablet (1) within the dispensing passage (9) as shown in Figs 5 and 6 prevents further tablets (1) from being dispensed, so that only one tablet (1) is dispensed at a time, and there is therefore a reduced possibility of spillage of excess unwanted tablets.
- the adapter (5) is made of resilient plastics the user can grip the projecting part of the tablet (1) and easily withdraw it for use against the releasable grip resulting from the resilience of the plastics material, but the tablet (1) is retained sufficiently to prevent it falling from the dispensing opening (10) under the action of gravity alone.
- FIG 4 a version of the mouth opening of the container of Figs. 2 and 3 is shown, of generally similar construction and operation to Figs 2 and 3, but having upstream extending cut outs (18) in opposite side walls (8) facing each other opposite the width of the passage (9).
- Such a passage may be constricted in the manner shown in Fig 6 and described with respect thereto, but the cut outs (18) allow a greater proportion of the tablet (1 not shown in Fig 4) to be gripped by the user.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Glass Compositions (AREA)
Claims (9)
- Behälter, der Tabletten (1) enthält, welche eine Form aufweisen, die in einer Ebene abgeflacht ist, mit einem Speicherabteil (3) innerhalb eines Behälterkörpers (2) zum Aufbewahren einer Tablettenmenge, wobei das Speicherabteil über eine oder mehrere Abgabedurchlässe (9) mit einer oder mehreren entsprechenden Abgabeöffnungen (10) jeweils an einem austrittsseitigen Ende des Abgabedurchlasses (9) verbunden ist, dadurch gekennzeichnet, daß die Abgabeöffnung und/oder der unmittelbar eintrittsseitig angrenzende Teil des Abgabedurchlasses zwischen eine Einengung bildenden Teilen, die einander gegenüberliegend quer zu der Öffnung oder dem Durchlaß (16, 17) angeordnet sind, in einer Weise eingeengt sind, daß eine den Abgabedurchlaß (9) längs passierende Tablette (1) lösbar zwischen den die Einengung bildenden Teilen an dem schmalsten Teil der Einengung (16, 17) erfaßt wird, in dem Abgabedurchlaß (9) mit einem ausreichenden Anteil der Tablette (1) aus der Abgabeöffnung (10) in der Richtung des Abgabedurchlasses hervorragt, daß der hervorragende Anteil von dem Benutzer erfaßt und die Tablette in der Richtung des Abgabedurchlasses herausgezogen werden kann.
- Behälter nach Anspruch 1, dadurch gekennzeichnet, daß der Querschnitt der Abgabeöffnung (10) in der Form dem Querschnitt der Tablette (1) senkrecht zu der Ebene, in welcher die Tablette abgeflacht ist, entspricht.
- Behälter nach Anspruch 1 oder 2, dadurch gekennzeichnet, daß die Abgabeöffnung (10) durch eine Lippe gebildet wird, welche das austrittsseitige Ende der den Durchlaß bildenden Wände (8) ist, welche sich von der Abgabeöffnung (10) eintrittsseitig erstrecken, um einen Abgabedurchlaß (9) zwischen den den Durchlaß bildenden Wänden (8) eintrittsseitig von der Abgabeöffnung (10) zu bilden.
- Behälter nach Anspruch 3, dadurch gekennzeichnet, daß die den Durchlaß bildenden Wände (8) sich verjüngen und sich dabei an eine schlitzförmige Abgabeöffnung (10) annähern und diese ausbilden.
- Behälter nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß das lösbare Halten der Tablette (1) durch die Lippe der Abgabeöffnung (10) und/oder ein eintrittsseitig angrenzendes Teil des Abgabedurchlasses (9) gebildet wird, das bis zu einem Grad elastisch ist, daß die Einengung (16, 17) leicht durch den Vorgang des Herausziehens der Tablette (1) weggedrückt werden kann.
- Behälter nach einem der Ansprüche 1 bis 5, dadurch gekennzeichnet, daß die Abgabeöffnung (10) und/oder das unmittelbar eintrittsseitig angrenzende Teil der Abgabedurchlaß (9) durch eine Verengung (16) der Öffnung und/oder den Durchlaß formende Wände (8) in Bezug auf einen eintrittsseitigen Teil des Abgabedurchlasses (9) mittels sich nach innen erstreckender Vorsprünge (17), oder durch eine Kombination von zwei oder mehr solcher Einengungsarten eingeengt sind.
- Behälter nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, daß die Einengung (16, 17) an der Abgabeöffnung (10), oder relativ zu der Länge des Abgabedurchlasses (9) innerhalb der Breite einer Tablette (1) oder eines Durchmessers im Falle runder Tabletten (1) eintrittsseitig von der Abgabeöffnung (10) angeordnet ist.
- Behälter nach einem der Ansprüche 1 bis 7, dadurch gekennzeichnet, daß es einen oder mehrere Ausschnitte (18) in den den Durchlaß bildenden Wänden (8) gibt, die sich von der Abgabeöffnung (10) eintrittsseitig erstrecken, und dadurch das Erfassen eines größeren Oberflächenbereichs der Tablette (1) ermöglichen.
- Behälter nach einem der Ansprüche 1 bis 8, dadurch gekennzeichnet, daß die Abgabeöffnung(en) (10) und/oder der Abgabedurchlaß bzw. die Abgabedurchlässe (9) und deren jeweiligen ausbildenden Wände (8) getrennt in einem separaten Adapter (5) ausgebildet sind, der für eine Befestigung auf dem Hals des Behälterkörpers (2), welcher einen Speicherabschnitt (3) enthält, vorgesehen ist.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI9530198T SI0756567T1 (en) | 1994-04-16 | 1995-04-11 | Container for containing and dispensing tablets |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9407589 | 1994-04-16 | ||
GB9407589A GB9407589D0 (en) | 1994-04-16 | 1994-04-16 | Container |
PCT/EP1995/001337 WO1995028338A1 (en) | 1994-04-16 | 1995-04-11 | Container for containing and dispensing tablets |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0756567A1 EP0756567A1 (de) | 1997-02-05 |
EP0756567B1 true EP0756567B1 (de) | 1998-10-14 |
Family
ID=10753655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95916631A Expired - Lifetime EP0756567B1 (de) | 1994-04-16 | 1995-04-11 | Mit einer abgabevorrichtung versehener tablettenbehälter |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0756567B1 (de) |
JP (1) | JPH09511972A (de) |
AT (1) | ATE172166T1 (de) |
AU (1) | AU2306395A (de) |
DE (1) | DE69505367T2 (de) |
DK (1) | DK0756567T3 (de) |
ES (1) | ES2125010T3 (de) |
GB (1) | GB9407589D0 (de) |
HK (1) | HK1012317A1 (de) |
SG (1) | SG50704A1 (de) |
WO (1) | WO1995028338A1 (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9823234B2 (en) | 2013-02-04 | 2017-11-21 | Clariant Production (France) S.A.S. | Dispensing device for holding and dispensing strip-like objects |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602004001226T2 (de) | 2003-03-03 | 2007-03-29 | Airsec S.A.S | Vorrichtung zum verteilen von länglichen gegenständen mit einer hauptöffnung und mindestens einer weiteren länglichen öffnung |
FR2868403B1 (fr) | 2004-03-30 | 2006-06-09 | Airsec Sa | Dispositif de distribution, unite par unite, d'objets conformes tels que comprimes pharmaceutiques |
FR2901253B1 (fr) | 2006-05-19 | 2008-08-15 | Airsec Soc Par Actions Simplif | Ensemble opercule de stockage et de distribution avec limiteur de debit, de produits pharmaceutiques solides |
EP2394926B1 (de) | 2010-06-08 | 2015-01-07 | Clariant Production (France) S.A.S. | Kindersicherer Stopfen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2918167A (en) * | 1957-12-19 | 1959-12-22 | Lowen Stanley | Pill or tablet dispenser |
US2962190A (en) * | 1958-04-21 | 1960-11-29 | Horland Richard | Pill dispensing unit |
FR1213811A (fr) * | 1958-10-29 | 1960-04-04 | Brev De L Ingenieur Savary Soc | Dispositif de distribution d'objets tels que des pilules |
EP0531394B1 (de) * | 1990-06-04 | 1997-03-19 | Toren Consulting Pty. Limited | Behälter zur ausgabe von tabletten |
-
1994
- 1994-04-16 GB GB9407589A patent/GB9407589D0/en active Pending
-
1995
- 1995-04-11 ES ES95916631T patent/ES2125010T3/es not_active Expired - Lifetime
- 1995-04-11 AT AT95916631T patent/ATE172166T1/de not_active IP Right Cessation
- 1995-04-11 JP JP7526696A patent/JPH09511972A/ja active Pending
- 1995-04-11 DK DK95916631T patent/DK0756567T3/da active
- 1995-04-11 AU AU23063/95A patent/AU2306395A/en not_active Abandoned
- 1995-04-11 SG SG1996009147A patent/SG50704A1/en unknown
- 1995-04-11 DE DE69505367T patent/DE69505367T2/de not_active Expired - Fee Related
- 1995-04-11 EP EP95916631A patent/EP0756567B1/de not_active Expired - Lifetime
- 1995-04-11 WO PCT/EP1995/001337 patent/WO1995028338A1/en active IP Right Grant
-
1998
- 1998-12-15 HK HK98113462A patent/HK1012317A1/xx not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9823234B2 (en) | 2013-02-04 | 2017-11-21 | Clariant Production (France) S.A.S. | Dispensing device for holding and dispensing strip-like objects |
Also Published As
Publication number | Publication date |
---|---|
DK0756567T3 (da) | 1999-06-28 |
GB9407589D0 (en) | 1994-06-08 |
EP0756567A1 (de) | 1997-02-05 |
SG50704A1 (en) | 1998-07-20 |
JPH09511972A (ja) | 1997-12-02 |
DE69505367T2 (de) | 1999-04-01 |
HK1012317A1 (en) | 1999-07-30 |
AU2306395A (en) | 1995-11-10 |
ES2125010T3 (es) | 1999-02-16 |
ATE172166T1 (de) | 1998-10-15 |
WO1995028338A1 (en) | 1995-10-26 |
DE69505367D1 (de) | 1998-11-19 |
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