EP0708639A4 - Procedes et compositions utilises pour traiter la depression et d'autres affections avec de la sibutramine (+) optiquement pure - Google Patents
Procedes et compositions utilises pour traiter la depression et d'autres affections avec de la sibutramine (+) optiquement pureInfo
- Publication number
- EP0708639A4 EP0708639A4 EP93915449A EP93915449A EP0708639A4 EP 0708639 A4 EP0708639 A4 EP 0708639A4 EP 93915449 A EP93915449 A EP 93915449A EP 93915449 A EP93915449 A EP 93915449A EP 0708639 A4 EP0708639 A4 EP 0708639A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- sibutramine
- disorders
- compositions
- methods
- optically pure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90303492A | 1992-06-23 | 1992-06-23 | |
US903034 | 1992-06-23 | ||
PCT/US1993/005967 WO1994000047A1 (fr) | 1992-06-23 | 1993-06-22 | Procedes et compositions utilises pour traiter la depression et d'autres affections avec de la sibutramine (+) optiquement pure |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0708639A1 EP0708639A1 (fr) | 1996-05-01 |
EP0708639A4 true EP0708639A4 (fr) | 1997-08-20 |
Family
ID=25416828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93915449A Withdrawn EP0708639A4 (fr) | 1992-06-23 | 1993-06-22 | Procedes et compositions utilises pour traiter la depression et d'autres affections avec de la sibutramine (+) optiquement pure |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0708639A4 (fr) |
JP (1) | JPH07508281A (fr) |
AU (1) | AU4542993A (fr) |
CA (1) | CA2139000A1 (fr) |
WO (1) | WO1994000047A1 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020006964A1 (en) * | 1995-05-16 | 2002-01-17 | Young James W. | Methods of using and compositions comprising (+) sibutramine optionally in combination with other pharmacologically active compounds |
DE19518988A1 (de) * | 1995-05-29 | 1996-12-05 | Basf Ag | Verwendung arylsubstituierter Cyclobutylalkylamine zur Behandlung der Fettleibigkeit |
GB9619962D0 (en) * | 1996-09-25 | 1996-11-13 | Knoll Ag | Medical treatment |
US6476078B2 (en) | 1999-08-11 | 2002-11-05 | Sepracor, Inc. | Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction |
US6339106B1 (en) | 1999-08-11 | 2002-01-15 | Sepracor, Inc. | Methods and compositions for the treatment and prevention of sexual dysfunction |
US6331571B1 (en) | 1998-08-24 | 2001-12-18 | Sepracor, Inc. | Methods of treating and preventing attention deficit disorders |
US6974838B2 (en) | 1998-08-24 | 2005-12-13 | Sepracor Inc. | Methods of treating or preventing pain using sibutramine metabolites |
US6046242A (en) * | 1998-11-27 | 2000-04-04 | Basf Aktiengesellschaft | Use of aryl-substituted cyclobutylalkylamines for treating urinary incontinence |
US6197828B1 (en) | 1998-12-01 | 2001-03-06 | Sepracor, Inc. | Derivatives of (+)-venlafaxine and methods of preparing and using the same |
US6342533B1 (en) | 1998-12-01 | 2002-01-29 | Sepracor, Inc. | Derivatives of (−)-venlafaxine and methods of preparing and using the same |
US6323242B1 (en) * | 1998-12-02 | 2001-11-27 | Peter Sterling Mueller | Treatment of disorders secondary to organic impairments |
US6696495B2 (en) | 1998-12-02 | 2004-02-24 | Snowden Pharmaceuticals, Llc | Treatment of disorders secondary to organic impairments |
MXPA01009461A (es) * | 1999-03-19 | 2004-03-19 | Abbott Gmbh & Co Kg | Tratamiento de osteoartritis. |
CA2368083A1 (fr) | 1999-04-06 | 2000-10-12 | Sepracor Inc. | Derives de la venlafaxine et leurs procedes de preparation et utilisation |
US6399826B1 (en) | 1999-08-11 | 2002-06-04 | Sepracor Inc. | Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain |
US20020115727A1 (en) * | 2000-12-04 | 2002-08-22 | Senanayake Chris H. | Synthesis, methods of using, and compositions of hydroxylated cyclobutylalkylamines |
DK1360169T3 (da) | 2001-02-12 | 2007-11-26 | Wyeth Corp | Succinatsalt af O-desmethyl-venlafaxin |
US6610887B2 (en) | 2001-04-13 | 2003-08-26 | Sepracor Inc. | Methods of preparing didesmethylsibutramine and other sibutramine derivatives |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3008993A1 (de) * | 1980-03-08 | 1981-10-01 | Röhm Pharma GmbH, 6100 Darmstadt | Pharmazeutische zubereitungen |
GB2098601B (en) * | 1981-04-02 | 1985-07-24 | Sandoz Products Ltd | Improvements in or relating to organic compounds |
ZA821577B (en) * | 1981-04-06 | 1983-03-30 | Boots Co Plc | Therapeutic agents |
GB8531071D0 (en) * | 1985-12-17 | 1986-01-29 | Boots Co Plc | Therapeutic compound |
JP2675573B2 (ja) * | 1988-03-31 | 1997-11-12 | 科研製薬株式会社 | 脳機能改善剤 |
-
1993
- 1993-06-22 AU AU45429/93A patent/AU4542993A/en not_active Abandoned
- 1993-06-22 JP JP6502537A patent/JPH07508281A/ja active Pending
- 1993-06-22 EP EP93915449A patent/EP0708639A4/fr not_active Withdrawn
- 1993-06-22 CA CA002139000A patent/CA2139000A1/fr not_active Abandoned
- 1993-06-22 WO PCT/US1993/005967 patent/WO1994000047A1/fr not_active Application Discontinuation
Non-Patent Citations (2)
Title |
---|
No further relevant documents disclosed * |
See also references of WO9400047A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU4542993A (en) | 1994-01-24 |
EP0708639A1 (fr) | 1996-05-01 |
CA2139000A1 (fr) | 1994-01-06 |
WO1994000047A1 (fr) | 1994-01-06 |
JPH07508281A (ja) | 1995-09-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19950118 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
RHK1 | Main classification (correction) |
Ipc: A61K 31/135 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19970704 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 19991119 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: SEPRACOR INC. |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20050101 |