EP0694163A1 - Detecteur a deux capteurs destine a detecter la presence d'air dans une conduite de liquide - Google Patents

Detecteur a deux capteurs destine a detecter la presence d'air dans une conduite de liquide

Info

Publication number
EP0694163A1
EP0694163A1 EP95911606A EP95911606A EP0694163A1 EP 0694163 A1 EP0694163 A1 EP 0694163A1 EP 95911606 A EP95911606 A EP 95911606A EP 95911606 A EP95911606 A EP 95911606A EP 0694163 A1 EP0694163 A1 EP 0694163A1
Authority
EP
European Patent Office
Prior art keywords
tubing
passage
receiver
receivers
transmitter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95911606A
Other languages
German (de)
English (en)
Other versions
EP0694163A4 (fr
Inventor
Hal C. Danby
Alan Keith Brundle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Publication of EP0694163A1 publication Critical patent/EP0694163A1/fr
Publication of EP0694163A4 publication Critical patent/EP0694163A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • A61M5/365—Air detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots

Definitions

  • This invention relates to devices for detecting gas, e.g. air or air bubbles, in fluid conducting tubing and in particular in fluid conducting tubing forming part of a fluid flow system utilized for the intravenous supply of fluid to a medical patient.
  • gas e.g. air or air bubbles
  • the known device includes a body member 1 having a passage 2 passing therethrough in which may be accommodated a length of transparent walled p.v.c. tubing 3.
  • Passage 2 is open at the top (as viewed) in order that the tubing 3 may readily be slotted into position and of course removed after use.
  • Extending into the body 1 from its base and right-hand side (as viewed) respectively are two circular-cylindrical passages 4 and 5 which are orthogonal to each other and exit via apertures 6, 7 respectively into tubing passage 2.
  • an infra-red receiver 8 Located in circular cylindrical passage 4 is an infra-red receiver 8 (a phototransistor) which receives infra-red energy transmitted by an infra-red transmitter 9 (an LED).
  • the output level of receiver 8 depends upon the nature of the fluid passing through the tubing 3 past receiver 8 and transmitter 9. Different fluids will result in different output levels with a significant change if a gas, e.g. air, is present.
  • a gas e.g. air
  • a voltmeter 10 connected to the output of a suitable detector circuit 11 was found to indicate 0.1 volts when the fluid passing through tubing 3 was distilled water; 0.2 volts when the fluid was semi-skimmed milk; 1.4 volts when the fluid was a 20% intralipid solution and 4.2 volts when air passed through.
  • a device as shown in Figure 1 will therefore operate as a detector of air passing through tubing 3.
  • p.v.c. tubing typically used in a clinical analyzer is small bore thick-walled tubing with an outside diameter of 2.5mm and an inside diameter of 0.9mm.
  • the standard p.v.c. tubing used is of relatively large bore and thin walled having an outside diameter of 4mm and an inside diameter of 3.1mm.
  • FIG. 1 were insufficiently marked for the device to be regarded as useful in this connection.
  • an optical spacer between the transmitter and the tubing, and the tubing and the receiver and with this, markedly improved results were achieved.
  • Such an optical spacer is known from EP-A-0481656, which discloses a device for detecting the presence of air in liquid conducting, translucent or transparent tubing, the device comprising a passage for accommodating of said tubing, a transmitter for transmitting radiation (in this case, light) towards said passage; a receiver for receiving radiation from said passage which has passed through the tubing, the receiver being operable to produce an output signal (i) when air is present in the tubing and/or (ii) when the dilution ratio of the liquid in the tubing is below a first predetermined threshold; and processing means.
  • the processing means processes said output signal to provide an indication that air is present in the tubing.
  • the device tends to make a false detection that air is present in instances defined in (ii) above.
  • Claim 1 relates to an improvement of the device of EP-A-0481656, wherein the improvement comprises means for eliminating false detections made by the receiver, that gas is present in the tubing, and comprising means (iii) a second receiver for receiving from said passage radiation which has passed through said tubing, the second receiver being operable to produce an output signal when gas is present in the tubing, the second receiver making false detections under different liquid conditions from the first receiver, and (iv) processing means operatively connected to both receivers to receive said output signals to provide an indication that gas is present in the tubing only when the output signals from both receivers are present.
  • the transmitter and receivers are respectively a light energy transmitter and light energy receivers and are all operative in the infra-red spectrum, and preferably the transmitter is a LED (light emitting diode) and the receivers are phototransistors.
  • the device includes an optical spacer defining said passage and occupying space between said passage and said transmitter and between said passage and said receivers, the optical spacer comprising a cylindrical element having a dielectric constant greater than that of air, said tubing passage extending along a longitudinal axis of the cylindrical element for accommodating said tubing in intimate contact with said cylindrical element.
  • the optical spacer is in the form of a collar surrounding the tubing, the transmitter and the receivers being housed in the body.
  • the transmitter and the receivers are located in passages extending through the body and opening towards the tubing accommodating passage.
  • the transmitter and receiver locating passages open towards the tubing accommodating passage via respective apertures.
  • the apertures may be in fixed walls, integral with the body, which otherwise close the passages or in plugs inserted in the passages otherwise to close the same.
  • the apertures may be of different sizes chosen to provide optimum effect in any given device. Commonly, the aperture through which the transmitter communicates will be of smaller cross-sectional area than the apertures through which the receivers communicate. In one embodiment wherein the apertures are of circular cross-section, the diameter of the aperture through which the transmitter communicates is at least approximately half the diameter of the apertures through which the receivers communicate.
  • the transmitter and receivers are spaced around the tubing accommodating passage, preferably with their principle optical axis in the same transverse plane.
  • the receivers are arranged with their principle optic axes orthogonal one to the other. Where the axes lie in the same transverse plane it may be found that satisfactory results are obtained with the optic axes at some relative angle other than 90° but it is believed that optimum results are obtained when the axes are orthogonal one to the other.
  • spacing the transmitter and receivers along the length of the tubing accommodating passage may be found to give satisfactory results but arranging the transmitter and receivers such that their principle optic axes are spaced around the tubing accommodating passage is believed to provide optimum results.
  • the tubing used in the intravenous supply of fluids to a patient is of course of circular cross- section and therefore for this application the tubing accommodating passage is normally of circular cross-section.
  • the outer diameter of the optical spacer when present, will be between twice and three times the outside diameter of said tubing. In a preferred embodiment the outer diameter of the spacer is 2.5 times the outer diameter of the tubing.
  • the transmitter and receivers are discrete devices and preferably an LED (light emitting diode) and phototransistors, respectively. Normally such components are generally circular-cylindrical in overall outline and accordingly, the transmitter and receiver passages are normally circularly cylindrical.
  • the tubing accommodating passage has a linearly extending slot through which the tubing may be slotted.
  • the material chosen for the optical spacer when present, should have a dielectric constant which is an optically reasonable match to the material of said tubing.
  • the material is acrylic.
  • the transmitter projects a light beam to the fluid conducting tube and light receivers in the form of a pair of sensors disposed perpendicularly to each other operate in opposite modes such that if an air bubble is present in the line the detector will be able to reliably distinguish this situation from the case where there is no air bubble.
  • One sensor is disposed 90° from the optical axis of the transmitter, while the other sensor is disposed 180°, ie., along the transmitter optical axis.
  • Light beams projected from the transmitter are incident on the tubing and are thus reflected or transmitted depending upon the characteristics of the fluid (eg., the opacity of the fluid and/or dilution ratio of the fluid) and also upon the presence or absence of air or air bubbles in the line.
  • the two perpendicularly disposed sensors provide outputs indicative of the amount of light received.
  • a processor determines the presence or absence of air in the line based on the combination of the outputs of the two sensors. When the outputs of both sensors are high, the processor determines that air is present in the line, whereas if one of the two sensors' outputs is low, the processing device determines that no air is present in the line. With this arrangement, both sensor outputs are used in order to determine the presence or absence of air or air bubbles in the fluid conducting tubing, thus providing a reliable detection apparatus regardless of the initial calibration of the sensors and transmitter.
  • Figure 1 is a cross-sectional view of a conventional device for detecting air in tubing
  • Figure 2 is a transverse cross-sectional view of the device disclosed in
  • EP-A-0481656 for detecting the presence of air in tubing forming part of a fluid flow system for the intravenous supply of fluid to a medical patient;
  • Figure 3 shows an arrangement of an embodiment according to the present invention wherein a single transmitter and a pair of sensors which are provided perpendicularly to each other are shown;
  • FIG 4 illustrates the output of sensor 20a shown in Figure 3
  • Figure 5 shows the output of sensor 20b shown in Figure 3;
  • Figure 6 illustrates a graph of the values shown in Table 1 for a "best calibration" case
  • Figure 7 is a graph of the values of Table 1 for the "worst case" calibration.
  • Figure 8 is a circuit diagram illustrating the relationship between the transmitter and sensors of Figure 3.
  • a device as disclosed in EP-A-0481656 includes a body member 12 having a tubing accommodating passage 13 passing therethrough in which may be accommodated a length of transparent large bore thin-walled p.v.c. tubing 14.
  • Tubing 14 has an internal diameter of 3.0mm and an outside diameter of 4.1mm.
  • Passage 13 preferably has a diameter equal to 10mm.
  • an optical spacer 15 Located within passage 13 is an optical spacer 15 of material chosen to be a good optical match with the material of the tubing 14. In this case the material of the optical spacer 15 is acrylic.
  • the optical spacer 15 surrounds the tubing 14 save for a gap 16 which is of width sufficient for the tubing 14 to pass through.
  • Gap 16 is aligned with a slot 17, of similar width, extending longitudinally through the top (as viewed) of the passage 13.
  • the slot 17 and gap 16 enable the tubing 14 to be readily slotted into position and removed after use.
  • Circular-cylindrical passages 18, 19 are orthogonal to each other and exit via apertures 22, 23, respectively, into tubing accommodating passage 13.
  • the openings of apertures 22, 23 in passage 13 are covered by the outer surface of optical spacer 15.
  • the receiver and transmitter apertures 22, 23 are not of the same diameter.
  • the diameter of transmitter aperture 23 is one-half that of receiver aperture 22.
  • a test corresponding to that described earlier in reference to Figure 1 provided an indication of 0.3 volts when the fluid passage through tubing 14 was distilled water; 1.2 volts when the fluid was semi-skimmed milk; 1.2 volts when the fluid was 20% intralipid solution and 4.0 volts when air passed through.
  • the phototransistors 20a, 20b of type BPW 77 also operate in the infrared spectrum wherein sensor 20a is provided at a right angle to the direction of incidence of the light beam from the transmitter, while sensor 20b is provided along a path parallel to the direction of light beam incidence, ie., at a 180° angle.
  • a transparent optical spacer 15 which may be of acrylic material, for example, is also provided within a tubing accommodating passage 13 in the body member 12 for holding the large- bore thin-walled tubing 14.
  • the transmitter and first and second energy receivers are located in respective passages which extend through the body member and open into the tubing accommodating passage.
  • Apertures 22, 23, 24 are shown which connect the tubing accommodating passage with each of the respective passages provided for the transmitter and receivers.
  • the apertures may be of different sizes for each of the receivers and transmitter or, alternatively, may be the same size for two of these elements and of a different size for the third element.
  • the transmitter aperture may be of smaller cross-sectional area than the aperture through which light is received by the first and second receivers.
  • the apertures are of circular cross-section with the diameter of the aperture through which the transmitter transmits light being approximately 1.5 times greater than the diameter of the apertures through which the first and second receivers communicate with the tubing accommodating passage.
  • a suitable diameter for the optical spacer is between 2 and 3 times larger than the outer diameter of the large-bore thin-walled tubing.
  • a preferred outer diameter of the tubing accommodating passage is approximately 2.5 times greater than the outer diameter of the tubing.
  • the voltage outputs provided by sensors 20a and 20b are as shown in Figures 4 and 5.
  • the output of sensor 20a alone will provide satisfactory results provided that the calibration of the transmitter and sensor is within a predetermined range.
  • the output of sensor 20a at a dilution ration of 9/1 for a 20% intralipid solution may be equal to the calibrated output of sensor 20a, ie., the air setting value.
  • the output of each of the sensors will be high, ie., will be equal to the air setting or calibration value.
  • the output of sensor 20a is substantially equal to the output of sensor 20a for the case when an air bubble is present
  • the output of sensor 20b will also be high (3 volts) and equal to the air setting value.
  • the detector device according to the present invention will be able to reliably detect when an air bubble is in fact present in the fluid conducting tubing.
  • the output of sensor 20a may be high but the output of sensor 20b will be low, thereby indicating that no air bubbles are present.
  • Dense Fluid Low or High Low Figure 8 illustrates the circuit diagram arrangement of the transmitter and sensors of Figure 3.
  • the transmitter 21 is connected in series with a resistor R, equal to 100 ohms in a preferred embodiment, and is connected between a 5 volt source and ground.
  • the angle between the light beams received by sensor 20a and those received by sensor 20b is equal to 90° since the sensors are at right angles to each other, and thus the angle illustrated in Figure 8 is not to be considered the actual angle between sensors 20a and 20b.
  • Output terminals 32, 31 of sensors 20a, 20b respectively, are connected to ground through 200 K ⁇ variable resistors R 2 , R 3 , respectively.
  • the outputs of sensors 20a, 20b are input to a processing device 33 which determines the presence or absence of air in the tubing 14 and outputs appropriate signals to a display device (now shown).
  • Processing device 33 outputs a first signal when the outputs of sensors 20a and 20b are both high, a second signal when the output of sensor 20a is low and sensor 20b is high (indicating water or a highly low diluted solution), and a third signal whenever the output of sensor 20b is low (indicating a dense fluid at low dilution).
  • the processing device 33 may include a microprocessor operating under program control for generating the appropriate output signals corresponding to the outputs received from the sensors 20a, 20b thereby indicating the presence or absence of air in the line.
  • the processing device 33 may include discrete logic circuits for receiving the outputs of the light receivers and generating the requisite outputs.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un dispositif destiné à détecter la présence de gaz, par exemple d'air, dans un tuyau (14) véhiculant un liquide. Le dispositif comprend un émetteur (21) qui émet un faisceau lumineux en direction du liquide contenu dans le tuyau (14), et un premier et un second récepteur de lumière (20a, 20b) qui reçoivent la lumière émise par l'émetteur (21), réfléchie et transmise après avoir frappé le liquide dans le tuyau. Les récepteurs de lumière sont situés dans un corps (12) entourant le tuyau conduisant le liquide, chacun de ces récepteurs produisant un signal correspondant à l'état du liquide se trouvant dans le tuyau. Les deux récepteurs produisent un signal prédéterminé lorsque du gaz est présent dans le liquide, mais chaque récepteur produit également un tel signal lorsque le liquide est dans un état différent. Le dispositif présenté comprend également un moyen de traitement (33) qui réagit aux signaux de sortie des deux récepteurs et indique la présence de gaz dans le tuyau seulement lorsque les deux récepteurs envoient le signal prédéterminé correspondant à la présence de gaz dans le liquide.
EP95911606A 1994-02-05 1995-02-03 Detecteur a deux capteurs destine a detecter la presence d'air dans une conduite de liquide Withdrawn EP0694163A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9402256 1994-02-05
GB9402256A GB9402256D0 (en) 1994-02-05 1994-02-05 Dual sensor air-in-line detector
PCT/US1995/001424 WO1995021374A1 (fr) 1994-02-05 1995-02-03 Detecteur a deux capteurs destine a detecter la presence d'air dans une conduite de liquide

Publications (2)

Publication Number Publication Date
EP0694163A1 true EP0694163A1 (fr) 1996-01-31
EP0694163A4 EP0694163A4 (fr) 2000-02-23

Family

ID=10749956

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95911606A Withdrawn EP0694163A4 (fr) 1994-02-05 1995-02-03 Detecteur a deux capteurs destine a detecter la presence d'air dans une conduite de liquide

Country Status (9)

Country Link
EP (1) EP0694163A4 (fr)
JP (1) JPH08508920A (fr)
KR (1) KR100344609B1 (fr)
AU (1) AU678709B2 (fr)
CA (1) CA2157582A1 (fr)
GB (1) GB9402256D0 (fr)
NO (1) NO953946L (fr)
NZ (1) NZ282105A (fr)
WO (1) WO1995021374A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111879665A (zh) * 2020-06-19 2020-11-03 西安交通大学 一种测量制冷剂/润滑油体系扩散性质的装置和方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009038495A1 (de) * 2009-08-21 2011-02-24 Medtron Ag Vorrichtung zur Detektion von Gasansammlungen
JP6404446B2 (ja) * 2015-02-19 2018-10-10 愛知時計電機株式会社 流速計測装置とそれに用いる管
CN110455718A (zh) * 2019-08-16 2019-11-15 佛山市川东磁电股份有限公司 一种液体及其浊度检测装置

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344429A (en) * 1979-12-13 1982-08-17 Baxter Travenol Laboratories, Inc. Bubble detector with feedback circuit for improved sensitivity
US4658244A (en) * 1985-03-28 1987-04-14 Imed Corporation Air-in-line detector
US4829448A (en) * 1984-09-24 1989-05-09 Vi-Tal Hospital Products Ltd. Air-in-line detector
EP0346548A1 (fr) * 1988-06-13 1989-12-20 PACESETTER INFUSION LTD. trading as MINIMED TECHNOLOGIES Détecteur de l'état vide d'un récipient

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366384A (en) * 1980-06-18 1982-12-28 Cutter Laboratories, Inc. Air bubble detector
US4857050A (en) * 1987-09-23 1989-08-15 Fisher Scientific Company Ratiometric air-in-line detector
US4920336A (en) * 1988-11-22 1990-04-24 Fisher Scientific Company Method and apparatus for monitoring the level of the contents in a container

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344429A (en) * 1979-12-13 1982-08-17 Baxter Travenol Laboratories, Inc. Bubble detector with feedback circuit for improved sensitivity
US4829448A (en) * 1984-09-24 1989-05-09 Vi-Tal Hospital Products Ltd. Air-in-line detector
US4658244A (en) * 1985-03-28 1987-04-14 Imed Corporation Air-in-line detector
EP0346548A1 (fr) * 1988-06-13 1989-12-20 PACESETTER INFUSION LTD. trading as MINIMED TECHNOLOGIES Détecteur de l'état vide d'un récipient

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9521374A1 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111879665A (zh) * 2020-06-19 2020-11-03 西安交通大学 一种测量制冷剂/润滑油体系扩散性质的装置和方法

Also Published As

Publication number Publication date
WO1995021374A1 (fr) 1995-08-10
CA2157582A1 (fr) 1995-08-10
AU1910995A (en) 1995-08-21
KR100344609B1 (ko) 2002-11-23
AU678709B2 (en) 1997-06-05
EP0694163A4 (fr) 2000-02-23
KR960702104A (ko) 1996-03-28
NO953946D0 (no) 1995-10-04
NZ282105A (en) 1997-09-22
NO953946L (no) 1995-12-04
GB9402256D0 (en) 1994-03-30
JPH08508920A (ja) 1996-09-24

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