EP0689547A4 - Cloned human alpha1c adrenergic receptor - Google Patents
Cloned human alpha1c adrenergic receptorInfo
- Publication number
- EP0689547A4 EP0689547A4 EP94912209A EP94912209A EP0689547A4 EP 0689547 A4 EP0689547 A4 EP 0689547A4 EP 94912209 A EP94912209 A EP 94912209A EP 94912209 A EP94912209 A EP 94912209A EP 0689547 A4 EP0689547 A4 EP 0689547A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- adrenergic receptor
- cloned human
- alpha1c
- alpha1c adrenergic
- cloned
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3284993A | 1993-03-15 | 1993-03-15 | |
US32849 | 1993-03-15 | ||
PCT/US1994/002609 WO1994021660A1 (en) | 1993-03-15 | 1994-03-10 | Cloned human alpha1c adrenergic receptor |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0689547A1 EP0689547A1 (en) | 1996-01-03 |
EP0689547A4 true EP0689547A4 (en) | 1998-10-28 |
Family
ID=21867151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94912209A Withdrawn EP0689547A4 (en) | 1993-03-15 | 1994-03-10 | Cloned human alpha1c adrenergic receptor |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0689547A4 (en) |
JP (1) | JPH08508163A (en) |
AU (1) | AU685789B2 (en) |
CA (1) | CA2158345A1 (en) |
WO (1) | WO1994021660A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5861309A (en) * | 1992-09-25 | 1999-01-19 | Synaptic Pharmaceutical Corporation | DNA endoding human alpha 1 adrenergic receptors |
US5578611A (en) * | 1992-11-13 | 1996-11-26 | Synaptic Pharmaceutical Corporation | Use of α-1C specific compounds to treat benign prostatic hyperplasia |
US6015819A (en) * | 1992-11-13 | 2000-01-18 | Synaptic Pharmaceutical Corporation | Use of alpha-1C specific compounds to treat benign prostatic hyperplasia |
US5403847A (en) * | 1992-11-13 | 1995-04-04 | Synaptic Pharmaceutical Corporation | Use of α1C specific compounds to treat benign prostatic hyperlasia |
US5952351A (en) * | 1995-02-23 | 1999-09-14 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
US6096763A (en) * | 1995-02-23 | 2000-08-01 | Merck & Co., Inc. | α1a adrenergic receptor antagonists |
US5668148A (en) * | 1995-04-20 | 1997-09-16 | Merck & Co., Inc. | Alpha1a adrenergic receptor antagonists |
US5661163A (en) * | 1995-06-07 | 1997-08-26 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
US5620993A (en) * | 1995-06-07 | 1997-04-15 | Merck & Co., Inc. | Alpha-1a adrenergic receptor antagonists |
US5807856A (en) * | 1995-11-15 | 1998-09-15 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonist |
CN100575368C (en) * | 2004-08-04 | 2009-12-30 | 积水化学工业株式会社 | The manufacture method of the manufacture method of polyvinyl acetal resin, polyvinyl butyral resin and esterified polyvinyl alcohol resin |
WO2006021344A1 (en) * | 2004-08-27 | 2006-03-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with alpha-1a adrenergic receptor (adra1a) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992016213A1 (en) * | 1991-03-20 | 1992-10-01 | Merck & Co., Inc. | Pharmaceutical combination for the treatment of prostatic hyperplasia, containing a 5 alpha-reductase inhibitor and an antiandrogen |
WO1993023038A1 (en) * | 1992-05-20 | 1993-11-25 | Merck & Co., Inc. | 17-AMINO SUBSTITUTED 4-AZASTEROID 5α-REDUCTASE INHIBITORS |
WO1994008040A1 (en) * | 1992-09-25 | 1994-04-14 | Synaptic Pharmaceutical Corporation | Dna encoding human alpha 1 adrenergic receptors and uses thereof |
WO1994010989A1 (en) * | 1992-11-13 | 1994-05-26 | Synaptic Pharmaceutical Corporation | Use of alpha-1c specific compounds to treat benign prostatic hyperplasia |
-
1994
- 1994-03-10 JP JP6521115A patent/JPH08508163A/en active Pending
- 1994-03-10 AU AU64453/94A patent/AU685789B2/en not_active Ceased
- 1994-03-10 CA CA 2158345 patent/CA2158345A1/en not_active Abandoned
- 1994-03-10 EP EP94912209A patent/EP0689547A4/en not_active Withdrawn
- 1994-03-10 WO PCT/US1994/002609 patent/WO1994021660A1/en not_active Application Discontinuation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992016213A1 (en) * | 1991-03-20 | 1992-10-01 | Merck & Co., Inc. | Pharmaceutical combination for the treatment of prostatic hyperplasia, containing a 5 alpha-reductase inhibitor and an antiandrogen |
WO1993023038A1 (en) * | 1992-05-20 | 1993-11-25 | Merck & Co., Inc. | 17-AMINO SUBSTITUTED 4-AZASTEROID 5α-REDUCTASE INHIBITORS |
WO1994008040A1 (en) * | 1992-09-25 | 1994-04-14 | Synaptic Pharmaceutical Corporation | Dna encoding human alpha 1 adrenergic receptors and uses thereof |
WO1994010989A1 (en) * | 1992-11-13 | 1994-05-26 | Synaptic Pharmaceutical Corporation | Use of alpha-1c specific compounds to treat benign prostatic hyperplasia |
Non-Patent Citations (6)
Title |
---|
BRUNO J.F. ET AL.: "Molecular cloning and sequencing of a cDNA encoding a human alpha1A adrenergic receptor.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 179, no. 3, 30 September 1991 (1991-09-30), pages 1485 - 1490, XP002059308 * |
HARISAWA A.: "Cloning, functional expression and tissue distribution of human cDNA for the alpha1C-adrenergic receptor.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 195, no. 2, 15 September 1993 (1993-09-15), pages 902 - 909, XP002059309 * |
LEPOR H ET AL: "THE ALPHA-ADRENOCEPTOR SUBTYPE MEDIATING THE TENSION OF HUMAN PROSTATIC SMOOTH MUSCLE", THE PROSTATE, vol. 22, no. 4, 16 June 1993 (1993-06-16), pages 301 - 307, XP002047748 * |
MELLIN T N ET AL: "AZASTEROIDS AS INHIBITORS OF TESTOSTERONE 5ALPHA-REDUCTASE IN MAMMALIAN SKIN", JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, vol. 44, no. 2, February 1993 (1993-02-01), pages 121 - 131, XP002028037 * |
SCHWINN D A & LOMASNEY J W: "Pharmacological characterization of cloned alpha 1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 227, no. 4, 1 December 1992 (1992-12-01), pages 433 - 436, XP002075428 * |
See also references of WO9421660A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0689547A1 (en) | 1996-01-03 |
JPH08508163A (en) | 1996-09-03 |
AU6445394A (en) | 1994-10-11 |
WO1994021660A1 (en) | 1994-09-29 |
AU685789B2 (en) | 1998-01-29 |
CA2158345A1 (en) | 1994-09-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19951016 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE |
|
RHK1 | Main classification (correction) |
Ipc: C12N 15/12 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19980910 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20010426 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20010907 |