EP0619744A4 - Nichtionische x-strahlen-kontrastmittel, zusammensetzungen und methoden. - Google Patents
Nichtionische x-strahlen-kontrastmittel, zusammensetzungen und methoden.Info
- Publication number
- EP0619744A4 EP0619744A4 EP93901365A EP93901365A EP0619744A4 EP 0619744 A4 EP0619744 A4 EP 0619744A4 EP 93901365 A EP93901365 A EP 93901365A EP 93901365 A EP93901365 A EP 93901365A EP 0619744 A4 EP0619744 A4 EP 0619744A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- nonionic
- compositions
- methods
- contrast agents
- ray contrast
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80198091A | 1991-12-03 | 1991-12-03 | |
PCT/US1992/010629 WO1993010825A1 (en) | 1991-12-03 | 1992-12-02 | Nonionic x-ray contrast agents, compositions and methods |
US801980 | 1997-02-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0619744A1 EP0619744A1 (de) | 1994-10-19 |
EP0619744A4 true EP0619744A4 (de) | 1995-02-08 |
Family
ID=25182519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP93901365A Withdrawn EP0619744A4 (de) | 1991-12-03 | 1992-12-02 | Nichtionische x-strahlen-kontrastmittel, zusammensetzungen und methoden. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0619744A4 (de) |
JP (1) | JPH07501809A (de) |
AU (1) | AU3273993A (de) |
CA (1) | CA2124559A1 (de) |
WO (1) | WO1993010825A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5622687A (en) * | 1994-11-15 | 1997-04-22 | Molecular Biosystems, Inc. | Calixarene conjugates useful as MRI and CT diagnostic imaging agents |
DE19510864A1 (de) * | 1995-03-16 | 1996-09-19 | Schering Ag | Röntgenkontrastmittel für die Computertomographie und Urographie |
IT1275429B (it) * | 1995-05-18 | 1997-08-07 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di composti organici |
DE19731591C2 (de) * | 1997-07-17 | 1999-09-16 | Schering Ag | Pharmazeutische Mittel enthaltend perfluoralkylgruppenhaltige Trijodaromaten und ihre Verwendung in der Tumortherapie und interventionellen Radiologie |
DE10215941A1 (de) | 2002-04-11 | 2003-10-23 | Bayer Ag | Anorganische UV-Absorber enthaltene Bindemittel |
US8679460B2 (en) | 2004-03-11 | 2014-03-25 | Mallinckrodt Llc | Low osmolar X-ray contrast media formulations |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
DE3038853A1 (de) * | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
-
1992
- 1992-12-02 CA CA002124559A patent/CA2124559A1/en not_active Abandoned
- 1992-12-02 EP EP93901365A patent/EP0619744A4/de not_active Withdrawn
- 1992-12-02 WO PCT/US1992/010629 patent/WO1993010825A1/en not_active Application Discontinuation
- 1992-12-02 JP JP5510391A patent/JPH07501809A/ja active Pending
- 1992-12-02 AU AU32739/93A patent/AU3273993A/en not_active Withdrawn
Non-Patent Citations (2)
Title |
---|
No further relevant documents disclosed * |
See also references of WO9310825A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0619744A1 (de) | 1994-10-19 |
WO1993010825A1 (en) | 1993-06-10 |
AU3273993A (en) | 1993-06-28 |
JPH07501809A (ja) | 1995-02-23 |
CA2124559A1 (en) | 1993-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19940701 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: WHEATLEY, JAMES Inventor name: LIN, YOULIN Inventor name: KNELLER, MILLS, T. |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19941223 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE |
|
17Q | First examination report despatched |
Effective date: 19950720 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19951201 |