EP0606783A1 - Droplet forming tip - Google Patents
Droplet forming tip Download PDFInfo
- Publication number
- EP0606783A1 EP0606783A1 EP19930400052 EP93400052A EP0606783A1 EP 0606783 A1 EP0606783 A1 EP 0606783A1 EP 19930400052 EP19930400052 EP 19930400052 EP 93400052 A EP93400052 A EP 93400052A EP 0606783 A1 EP0606783 A1 EP 0606783A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- filter element
- face
- channel
- liquid
- membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D47/00—Closures with filling and discharging, or with discharging, devices
- B65D47/04—Closures with discharging devices other than pumps
- B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
- B65D47/18—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
- A61J1/145—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using air filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
- A61J1/1456—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using liquid filters
Definitions
- the present invention relates to a drip tip adapted to be fixed to a container containing a liquid, in particular a pharmaceutical product, of the type described in the preamble of claim 1.
- the usual tips have a body adapted to be fixed, for example, in the neck of a bottle containing a liquid.
- the nozzle is crossed by a channel whose transverse dimensions are reduced, and the profile of the channel is determined by the liquid contained in the bottle so as to avoid a distribution by continuous jet of the liquid.
- one solution is to put bactericide in the product.
- the drops dispensed contain not only active product but also bactericide and the volume of liquid to be dispensed is greater than that necessary for treatment.
- the introduction of bactericide increases the cost of the product contained in the bottle, and does not ensure a constant amount of active product distributed in each drop.
- the solution comprises non-solubilized parts which can be evacuated through the channel of the nozzle.
- dropper tips have been proposed equipped with a filter preventing the passage of fine solid particles and / or bacteria between the inside and outside of the bottle and vice versa, and in particular tips of the aforementioned type (see for example FR-A-2 422 569).
- the invention aims to fill this gap and, for this purpose, it relates to a drip tip of the aforementioned type, characterized by the characterizing part of claim 1.
- the invention also relates to a container provided with a nozzle as described above.
- a nozzle 2 according to the prior art (see FIG. 1) comprises a body 4 through which is pierced a channel 6 opening on the one hand on an internal end face 8 of the nozzle located inside the bottle and on the other hand on an outer end face 10 of the nozzle.
- the passage section of the channel at the level of the internal end face 8 is relatively small, of the order, for example, of 0.2 millimeters in diameter.
- This dimension is predetermined, as a function of the liquid contained in the bottle, in order to obtain a predetermined drip rate of liquid.
- the passage section of the channel 6 at the level of the external end face 10 is of a predetermined size depending on the size of the desired drops.
- a channel flaring is thus obtained from the internal end face 8 to the external end face 10.
- the body of the end piece consists of a first part 22 and a second part 24, located in the extension of one another.
- a channel passes through the end piece 20, and comprises a first channel part 26 delimited by the first part 22 of the body and a second channel part 28 delimited by the second part 24 of the body.
- the section of the second channel part 28 is smaller than the section of the first channel part 26, delimiting a shoulder 30 externally delimited by a circular projection 31.
- a filter membrane 32 is arranged transversely between the two parts 26 and 28 of the channel, its periphery being applied against the shoulder 30 by the first part 22 of the body and being positioned by projection 31.
- the membrane 32 is an open porosity membrane, the doors of which have a diameter smaller than 0.2 microns.
- the membrane 32 prevents the passage of bacteria between the first and the second channel parts 26, 28 respectively, and vice versa.
- the flow rate that is to say the number of drops dispensed during a predetermined period of time, is a function of the viscosity of the fluid contained in the bottle and of the effective section of the membrane, this is ie the section of membrane through which the liquid crosses the pores of the membrane.
- the effective section of the membrane is limited by the passage section of the second part 28 of the channel adjacent to the membrane 32.
- the size of the drops is determined by the passage section of the channel 28 adjacent to the external end face 34 of the nozzle.
- the second part 28 of the channel may be cylindrical, as shown in FIG. 2, or have a flaring profile, or the like.
- FIG 3 there is shown a second embodiment of a nozzle 20 according to the invention in which the membrane 32 has been replaced by a filter element 42 composed of at least two superposed filter membranes with open porosity.
- One of these superimposed membranes is an open porosity membrane whose pores have a diameter smaller than 0.2 microns.
- a passage 44 has been arranged hollowed out in the shoulder 30.
- the passage 44 consists of a spiral groove 45 (see FIG. 4), open on its face in contact with the filter element 42, the inner end of the spiral groove communicating with the second channel part 28.
- the fluid flows through the membrane not only in the part located opposite the second part 28 of the channel, but also in the part opposite the passage 44 and then in the second part of channel 28 (see arrows in Figure 3).
- the passage 44 therefore constitutes a part of the effective passage section of the filter element.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Closures For Containers (AREA)
Abstract
Description
La présente invention concerne un embout goutte à goutte adapté pour être fixé sur un récipient contenant un liquide, notamment un produit pharmaceutique, du type décrit dans le préambule de la revendication 1.The present invention relates to a drip tip adapted to be fixed to a container containing a liquid, in particular a pharmaceutical product, of the type described in the preamble of claim 1.
Les embouts habituels comportent un corps adapté pour être fixé, par exemple, dans le goulot d'un flacon contenant un liquide. L'embout est traversé par un canal dont les dimensions transversales sont réduites, et le profil du canal est déterminé par le liquide contenu dans le flacon de manière à éviter une distribution par jet continu du liquide.The usual tips have a body adapted to be fixed, for example, in the neck of a bottle containing a liquid. The nozzle is crossed by a channel whose transverse dimensions are reduced, and the profile of the channel is determined by the liquid contained in the bottle so as to avoid a distribution by continuous jet of the liquid.
Avec de tels embouts, lorsque l'ensemble est débouché, le produit contenu dans le flacon se trouve en contact avec l'air ambiant, ce qui entraîne l'introduction de bactéries dans le produit.With such tips, when the assembly is uncorked, the product contained in the bottle is in contact with the ambient air, which causes the introduction of bacteria into the product.
Pour éviter le développement ou la survie de bactéries dans le produit, une solution consiste à mettre du bactéricide dans le produit.To avoid the growth or survival of bacteria in the product, one solution is to put bactericide in the product.
IL s'avère que dans ce cas, les gouttes distribuées contiennent non seulement du produit actif mais également du bactéricide et le volume de liquide à distribuer est plus grand que celui nécessaire au traitement.It turns out that in this case, the drops dispensed contain not only active product but also bactericide and the volume of liquid to be dispensed is greater than that necessary for treatment.
L'introduction de bactéricide augmente le coût du produit contenu dans le flacon, et n'assure pas une quantité constante de produit actif distribué dans chaque goutte.The introduction of bactericide increases the cost of the product contained in the bottle, and does not ensure a constant amount of active product distributed in each drop.
Par ailleurs, dans le cas où le produit actif est obtenu par dissolution d'une poudre dans un solvant, la solution comporte des parties non solubilisées qui peuvent être évacuées à travers le canal de l'embout. Un tel phénomène est gênant et même dangereux dans certains cas, le contrôle de la quantité de produit actif distribué n'étant pas rigoureux.Furthermore, in the case where the active product is obtained by dissolving a powder in a solvent, the solution comprises non-solubilized parts which can be evacuated through the channel of the nozzle. Such a phenomenon is embarrassing and even dangerous in some case, the control of the quantity of active product distributed is not rigorous.
Pour remédier à ces inconvénients, il a été proposé des embouts goutte à goutte équipés d'un filtre interdisant le passage de fines particules solides et/ou de bactéries entre l'intérieur et l'extérieur du flacon et inversement, et en particulier des embouts du type précité (voir par exemple FR-A-2 422 569).To overcome these drawbacks, dropper tips have been proposed equipped with a filter preventing the passage of fine solid particles and / or bacteria between the inside and outside of the bottle and vice versa, and in particular tips of the aforementioned type (see for example FR-A-2 422 569).
Toutefois, aucune solution fiable permettant à très faible coût et sans danger de détérioration pour la membrane d'obtenir une étanchéité parfaite à la périphérie de l'élément filtrant, n'a encore été proposée.However, no reliable solution has been proposed at very low cost and without danger of deterioration for the membrane to obtain a perfect seal at the periphery of the filter element.
L'invention a pour but de combler cette lacune et, à cet effet, elle a pour objet un embout goutte à goutte du type précité, caractérisé par la partie caractérisante de la revendication 1.The invention aims to fill this gap and, for this purpose, it relates to a drip tip of the aforementioned type, characterized by the characterizing part of claim 1.
D'autres caractéristiques sont décrites dans les sous-revendications 2 à 8.Other features are described in subclaims 2 to 8.
L'invention concerne également un récipient muni d'un embout tel que décrit ci-dessus.The invention also relates to a container provided with a nozzle as described above.
La présente invention sera mieux comprise à la lecture de la description détaillée qui va suivre, faite à titre d'exemple et en référence aux dessins annexés sur lesquels :
- la Figure 1 est une vue partielle en coupe d'un embout selon l'art antérieur;
- la Figure 2 est une vue en coupe d'un premier mode de réalisation d'un embout selon l'invention;
- la Figure 3 est une vue analogue à la Figure 2 d'un second mode de réalisation d'une embout selon l'invention; et
- la Figure 4 est une vue en coupe selon la ligne IV-IV de la Figure 3.
- Figure 1 is a partial sectional view of a tip according to the prior art;
- Figure 2 is a sectional view of a first embodiment of a nozzle according to the invention;
- Figure 3 is a view similar to Figure 2 of a second embodiment of a nozzle according to the invention; and
- Figure 4 is a sectional view along line IV-IV of Figure 3.
Un embout 2 selon l'art antérieur (voir Figure 1) comporte un corps 4 à travers lequel est percé un canal 6 ouvrant d'une part sur une face d'extrémité interne 8 de l'embout située à l'intérieur du flacon et d'autre part sur une face d'extrémité externe 10 de l'embout.A nozzle 2 according to the prior art (see FIG. 1) comprises a body 4 through which is pierced a
La section de passage du canal au niveau de la face d'extrémité interne 8 est relativement petite, de l'ordre, par exemple, de 0,2 millimètres en diamètre.The passage section of the channel at the level of the internal end face 8 is relatively small, of the order, for example, of 0.2 millimeters in diameter.
Cette dimension est prédéterminée, en fonction du liquide contenu dans le flacon, pour obtenir un débit de liquide goutte à goutte prédéterminé.This dimension is predetermined, as a function of the liquid contained in the bottle, in order to obtain a predetermined drip rate of liquid.
La section de passage du canal 6 au niveau de la face d'extrémité externe 10 est d'une dimension prédéterminée fonction de la taille des gouttes désirées.The passage section of the
On obtient ainsi un canal s'évasant depuis la face d'extrémité interne 8 jusqu'à la face d'extrémité externe 10.A channel flaring is thus obtained from the internal end face 8 to the
Sur la Figure 2, on a représenté un embout 20 selon l'invention.In Figure 2, there is shown a
Le corps de l'embout est constitué d'une première partie 22 et d'une seconde partie 24, situées dans le prolongement l'une de l'autre.The body of the end piece consists of a
Un canal traverse l'embout 20, et comporte une première partie de canal 26 délimitée par la première partie 22 du corps et une seconde partie de canal 28 délimitée par la seconde partie 24 du corps.A channel passes through the
La section de la seconde partie 28 de canal est plus petite que la section de la première partie 26 de canal, délimitant un épaulement 30 délimité extérieurement par une saillie circulaire 31.The section of the
Une membrane filtrante 32 est agencée transversalement entre les deux parties 26 et 28 du canal, sa périphérie étant appliquée contre l'épaulement 30 par la première partie 22 du corps et étant positionnée par la saillie 31.A
La membrane 32 est une membrane à porosité ouverte, dont les portes ont un diamètre plus petit que 0,2 microns.The
En d'autres termes, la membrane 32 interdit le passage de bactéries entre la première et la seconde parties de canal 26, 28 respectivement, et inversement.In other words, the
Dans un tel embout, le débit, c'est-à-dire le nombre de gouttes distribuées pendant un laps de temps prédéterminé, est fonction de la viscosité du fluide contenu dans le flacon et de la section efficace de la membrane, c'est-à-dire de la section de membrane à travers laquelle le liquide traverse les pores de la membrane.In such a nozzle, the flow rate, that is to say the number of drops dispensed during a predetermined period of time, is a function of the viscosity of the fluid contained in the bottle and of the effective section of the membrane, this is ie the section of membrane through which the liquid crosses the pores of the membrane.
Dans le mode de réalisation représenté sur la Figure 2, la section efficace de la membrane est limitée par la section de passage de la deuxième partie 28 de canal adjacente à la membrane 32.In the embodiment shown in FIG. 2, the effective section of the membrane is limited by the passage section of the
Comme dans l'art antérieur, la taille des gouttes est déterminée par la section de passage du canal 28 adjacente à la face d'extrémité externe 34 de l'embout.As in the prior art, the size of the drops is determined by the passage section of the
Selon le produit utilisé, le débit goutte à goutte désiré et la taille des gouttes à obtenir, la seconde partie 28 du canal peut être cylindrique, comme représenté sur la Figure 2, ou avoir un profil s'évasant, ou autre.Depending on the product used, the desired drip rate and the size of the drops to be obtained, the
Sur la Figure 3, on a représenté un deuxième mode de réalisation d'un embout 20 selon l'invention dans lequel la membrane 32 a été remplacée par un élément filtrant 42 composé d'au moins deux membranes filtrantes superposées à porosité ouverte.In Figure 3, there is shown a second embodiment of a
L'une de ces membranes superposées est une membrane à porosité ouverte dont les pores ont un diamètre plus petit que 0,2 microns.One of these superimposed membranes is an open porosity membrane whose pores have a diameter smaller than 0.2 microns.
Pour obtenir le débit désiré, c'est-à-dire une section de passage efficace adaptée, on a agencé un passage 44 creusé dans l'épaulement 30.To obtain the desired flow rate, that is to say a suitable effective passage section, a
Le passage 44 est constitué d'une gorge 45 (voir Figure 4) en spirale, ouverte sur sa face en contact avec l'élément filtrant 42, l'extrémité intérieure de la gorge en spirale communiquant avec la seconde partie de canal 28.The
Dans cet agencement, le fluide s'écoule à travers la membrane non seulement dans la partie située en vis-à-vis de la seconde partie 28 de canal, mais également dans la partie en vis-à-vis du passage 44 puis dans la seconde partie de canal 28 (voir les flèches de la Figure 3). Le passage 44 constitue donc une partie de la section de passage efficace de l'élément filtrant.In this arrangement, the fluid flows through the membrane not only in the part located opposite the
Pour réaliser l'embout selon l'invention, on met en oeuvre les étapes consistant à :
- mouler par injection d'une matière plastique la
seconde partie 24 du corps traversée par laseconde partie 28 de canal; - mettre l'élément filtrant en appui contre la face d'extrémité de la seconde partie du corps constituant l'épaulement 30;
- positionner en tant qu'insert l'ensemble élément filtrant-seconde partie du corps dans un moule d'injection dont la cavité est adaptée pour la formation de la
première partie 22 du corps; - surmouler la
première partie 22 du corps pour solidariser les deux parties du corps et l'élément filtrant, le surmoulage intéressant la périphérie de ce dernier et celle de laseconde partie 24 du corps.
- injection molding the
second part 24 of the body through which thesecond channel part 28 passes by a plastic material; - placing the filter element in abutment against the end face of the second part of the body constituting the
shoulder 30; - positioning the filter element-second part of the body as an insert in an injection mold, the cavity of which is suitable for forming the
first part 22 of the body; - overmolding the
first part 22 of the body to secure the two parts of the body and the filter element, the overmolding interesting the periphery of the latter and that of thesecond part 24 of the body.
Claims (9)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9108697A FR2678905B1 (en) | 1991-07-10 | 1991-07-10 | DRIP TIP. |
| EP19930400052 EP0606783A1 (en) | 1991-07-10 | 1993-01-13 | Droplet forming tip |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9108697A FR2678905B1 (en) | 1991-07-10 | 1991-07-10 | DRIP TIP. |
| EP19930400052 EP0606783A1 (en) | 1991-07-10 | 1993-01-13 | Droplet forming tip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP0606783A1 true EP0606783A1 (en) | 1994-07-20 |
Family
ID=26134634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP19930400052 Withdrawn EP0606783A1 (en) | 1991-07-10 | 1993-01-13 | Droplet forming tip |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP0606783A1 (en) |
| FR (1) | FR2678905B1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1245499A1 (en) * | 2001-03-13 | 2002-10-02 | Taisai Kako Co., Ltd. | Closing structure of a dispensing container |
| DE102008001313B3 (en) * | 2008-04-22 | 2009-06-04 | Stella Kunststofftechnik Gmbh | Drop cap for use with pressurized container i.e. drop dispenser, has entry channel formed in such manner to prevent channel from being filled by fluid i.e. liquid medicine, in flow direction without pressurization of pressurized container |
| CN106516397A (en) * | 2016-08-30 | 2017-03-22 | 嘉兴市腾翔塑业有限公司 | Liquid cosmetic discharge device |
| US9983151B2 (en) | 2014-05-08 | 2018-05-29 | Lawrence Livermore National Security, Llc | Ultralow-dose, feedback imaging with laser-Compton X-ray and laser-Compton gamma ray sources |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2678905B1 (en) * | 1991-07-10 | 1995-01-27 | Kerplas Snc | DRIP TIP. |
| DE69411816T2 (en) * | 1993-06-25 | 1998-12-03 | Alcon Cusi S A | New use of polymeric membranes for dispensing pharmaceutical solutions containing quaternary ammonium compounds used as preservatives and corresponding dosing containers |
| FR2934572A1 (en) * | 2008-07-31 | 2010-02-05 | Thea Lab | BOTTLE FOR FLASK OF LIQUID CONDITIONING TO DISPENSE DROP GOUTTE. |
| FR2974350B1 (en) * | 2011-04-21 | 2014-06-06 | Rexam Healthcare La Verpillier | LIQUID PRODUCT DISPENSING DEVICE WITH FLOW REDUCING MEMBER |
| KR101262161B1 (en) | 2011-12-20 | 2013-05-14 | 황재연 | Container for liquid contents of novel structure |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2422569A1 (en) * | 1978-04-14 | 1979-11-09 | Roussel Uclaf | STERILE LIQUID DISPENSER |
| DE3146343A1 (en) * | 1981-11-23 | 1983-10-20 | PROAQUA - PROVITA AG, 1700 Fribourg | Sterile-sealed container and method of producing it |
| US4414172A (en) * | 1982-05-21 | 1983-11-08 | Filtertek, Inc. | Process and apparatus for sealing a plurality of filter elements |
| WO1990005110A1 (en) * | 1988-11-03 | 1990-05-17 | Eye Research Institute Of Retina Foundation | Filter bottle |
| EP0401022A1 (en) * | 1989-06-01 | 1990-12-05 | Pall Corporation | Contamination-resistant dispensing and metering device |
| FR2678905A1 (en) * | 1991-07-10 | 1993-01-15 | Kerplas Snc | Dropper nozzle |
-
1991
- 1991-07-10 FR FR9108697A patent/FR2678905B1/en not_active Expired - Fee Related
-
1993
- 1993-01-13 EP EP19930400052 patent/EP0606783A1/en not_active Withdrawn
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2422569A1 (en) * | 1978-04-14 | 1979-11-09 | Roussel Uclaf | STERILE LIQUID DISPENSER |
| DE3146343A1 (en) * | 1981-11-23 | 1983-10-20 | PROAQUA - PROVITA AG, 1700 Fribourg | Sterile-sealed container and method of producing it |
| US4414172A (en) * | 1982-05-21 | 1983-11-08 | Filtertek, Inc. | Process and apparatus for sealing a plurality of filter elements |
| WO1990005110A1 (en) * | 1988-11-03 | 1990-05-17 | Eye Research Institute Of Retina Foundation | Filter bottle |
| EP0401022A1 (en) * | 1989-06-01 | 1990-12-05 | Pall Corporation | Contamination-resistant dispensing and metering device |
| FR2678905A1 (en) * | 1991-07-10 | 1993-01-15 | Kerplas Snc | Dropper nozzle |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1245499A1 (en) * | 2001-03-13 | 2002-10-02 | Taisai Kako Co., Ltd. | Closing structure of a dispensing container |
| US6672479B2 (en) | 2001-03-13 | 2004-01-06 | Taisai Kako Co., Ltd./Nihon Tenganyaku | Closing structure of a dispensing container |
| DE102008001313B3 (en) * | 2008-04-22 | 2009-06-04 | Stella Kunststofftechnik Gmbh | Drop cap for use with pressurized container i.e. drop dispenser, has entry channel formed in such manner to prevent channel from being filled by fluid i.e. liquid medicine, in flow direction without pressurization of pressurized container |
| DE102008001313B9 (en) * | 2008-04-22 | 2009-11-12 | Stella Kunststofftechnik Gmbh | drip cap |
| US9983151B2 (en) | 2014-05-08 | 2018-05-29 | Lawrence Livermore National Security, Llc | Ultralow-dose, feedback imaging with laser-Compton X-ray and laser-Compton gamma ray sources |
| CN106516397A (en) * | 2016-08-30 | 2017-03-22 | 嘉兴市腾翔塑业有限公司 | Liquid cosmetic discharge device |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2678905A1 (en) | 1993-01-15 |
| FR2678905B1 (en) | 1995-01-27 |
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