EP0606783A1 - Tropfgerät-Ansatzstück - Google Patents

Tropfgerät-Ansatzstück Download PDF

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Publication number
EP0606783A1
EP0606783A1 EP19930400052 EP93400052A EP0606783A1 EP 0606783 A1 EP0606783 A1 EP 0606783A1 EP 19930400052 EP19930400052 EP 19930400052 EP 93400052 A EP93400052 A EP 93400052A EP 0606783 A1 EP0606783 A1 EP 0606783A1
Authority
EP
European Patent Office
Prior art keywords
filter element
face
channel
liquid
membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19930400052
Other languages
English (en)
French (fr)
Inventor
Jean-François Grégoire
Jean Bonnelye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kerplas SNC
Original Assignee
Kerplas SNC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9108697A priority Critical patent/FR2678905B1/fr
Application filed by Kerplas SNC filed Critical Kerplas SNC
Priority to EP19930400052 priority patent/EP0606783A1/de
Publication of EP0606783A1 publication Critical patent/EP0606783A1/de
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/18—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • A61J1/145—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using air filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • A61J1/1456—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using liquid filters

Definitions

  • the present invention relates to a drip tip adapted to be fixed to a container containing a liquid, in particular a pharmaceutical product, of the type described in the preamble of claim 1.
  • the usual tips have a body adapted to be fixed, for example, in the neck of a bottle containing a liquid.
  • the nozzle is crossed by a channel whose transverse dimensions are reduced, and the profile of the channel is determined by the liquid contained in the bottle so as to avoid a distribution by continuous jet of the liquid.
  • one solution is to put bactericide in the product.
  • the drops dispensed contain not only active product but also bactericide and the volume of liquid to be dispensed is greater than that necessary for treatment.
  • the introduction of bactericide increases the cost of the product contained in the bottle, and does not ensure a constant amount of active product distributed in each drop.
  • the solution comprises non-solubilized parts which can be evacuated through the channel of the nozzle.
  • dropper tips have been proposed equipped with a filter preventing the passage of fine solid particles and / or bacteria between the inside and outside of the bottle and vice versa, and in particular tips of the aforementioned type (see for example FR-A-2 422 569).
  • the invention aims to fill this gap and, for this purpose, it relates to a drip tip of the aforementioned type, characterized by the characterizing part of claim 1.
  • the invention also relates to a container provided with a nozzle as described above.
  • a nozzle 2 according to the prior art (see FIG. 1) comprises a body 4 through which is pierced a channel 6 opening on the one hand on an internal end face 8 of the nozzle located inside the bottle and on the other hand on an outer end face 10 of the nozzle.
  • the passage section of the channel at the level of the internal end face 8 is relatively small, of the order, for example, of 0.2 millimeters in diameter.
  • This dimension is predetermined, as a function of the liquid contained in the bottle, in order to obtain a predetermined drip rate of liquid.
  • the passage section of the channel 6 at the level of the external end face 10 is of a predetermined size depending on the size of the desired drops.
  • a channel flaring is thus obtained from the internal end face 8 to the external end face 10.
  • the body of the end piece consists of a first part 22 and a second part 24, located in the extension of one another.
  • a channel passes through the end piece 20, and comprises a first channel part 26 delimited by the first part 22 of the body and a second channel part 28 delimited by the second part 24 of the body.
  • the section of the second channel part 28 is smaller than the section of the first channel part 26, delimiting a shoulder 30 externally delimited by a circular projection 31.
  • a filter membrane 32 is arranged transversely between the two parts 26 and 28 of the channel, its periphery being applied against the shoulder 30 by the first part 22 of the body and being positioned by projection 31.
  • the membrane 32 is an open porosity membrane, the doors of which have a diameter smaller than 0.2 microns.
  • the membrane 32 prevents the passage of bacteria between the first and the second channel parts 26, 28 respectively, and vice versa.
  • the flow rate that is to say the number of drops dispensed during a predetermined period of time, is a function of the viscosity of the fluid contained in the bottle and of the effective section of the membrane, this is ie the section of membrane through which the liquid crosses the pores of the membrane.
  • the effective section of the membrane is limited by the passage section of the second part 28 of the channel adjacent to the membrane 32.
  • the size of the drops is determined by the passage section of the channel 28 adjacent to the external end face 34 of the nozzle.
  • the second part 28 of the channel may be cylindrical, as shown in FIG. 2, or have a flaring profile, or the like.
  • FIG 3 there is shown a second embodiment of a nozzle 20 according to the invention in which the membrane 32 has been replaced by a filter element 42 composed of at least two superposed filter membranes with open porosity.
  • One of these superimposed membranes is an open porosity membrane whose pores have a diameter smaller than 0.2 microns.
  • a passage 44 has been arranged hollowed out in the shoulder 30.
  • the passage 44 consists of a spiral groove 45 (see FIG. 4), open on its face in contact with the filter element 42, the inner end of the spiral groove communicating with the second channel part 28.
  • the fluid flows through the membrane not only in the part located opposite the second part 28 of the channel, but also in the part opposite the passage 44 and then in the second part of channel 28 (see arrows in Figure 3).
  • the passage 44 therefore constitutes a part of the effective passage section of the filter element.
EP19930400052 1991-07-10 1993-01-13 Tropfgerät-Ansatzstück Withdrawn EP0606783A1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR9108697A FR2678905B1 (fr) 1991-07-10 1991-07-10 Embout goutte a goutte.
EP19930400052 EP0606783A1 (de) 1991-07-10 1993-01-13 Tropfgerät-Ansatzstück

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9108697A FR2678905B1 (fr) 1991-07-10 1991-07-10 Embout goutte a goutte.
EP19930400052 EP0606783A1 (de) 1991-07-10 1993-01-13 Tropfgerät-Ansatzstück

Publications (1)

Publication Number Publication Date
EP0606783A1 true EP0606783A1 (de) 1994-07-20

Family

ID=26134634

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19930400052 Withdrawn EP0606783A1 (de) 1991-07-10 1993-01-13 Tropfgerät-Ansatzstück

Country Status (2)

Country Link
EP (1) EP0606783A1 (de)
FR (1) FR2678905B1 (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1245499A1 (de) * 2001-03-13 2002-10-02 Taisai Kako Co., Ltd. Schliessstruktur für ein Ausgabebehälter
DE102008001313B3 (de) * 2008-04-22 2009-06-04 Stella Kunststofftechnik Gmbh Tropfkappe
CN106516397A (zh) * 2016-08-30 2017-03-22 嘉兴市腾翔塑业有限公司 液态化妆品出液器
US9983151B2 (en) 2014-05-08 2018-05-29 Lawrence Livermore National Security, Llc Ultralow-dose, feedback imaging with laser-Compton X-ray and laser-Compton gamma ray sources

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678905B1 (fr) * 1991-07-10 1995-01-27 Kerplas Snc Embout goutte a goutte.
FI108514B (fi) * 1993-06-25 2002-02-15 Cusi Lab Polymeerimembraanien käyttö sellaisten farmaseuttisten liuosten jakelussa, jotka sisältävät kvaternäärisiä ammoniumyhdisteitä
FR2934572A1 (fr) * 2008-07-31 2010-02-05 Thea Lab Embout pour flacon de conditionnement de liquide a distribuer goutte a goutte.
FR2974350B1 (fr) * 2011-04-21 2014-06-06 Rexam Healthcare La Verpillier Dispositif de distribution de produit liquide muni d'un organe de reduction de debit
KR101262161B1 (ko) 2011-12-20 2013-05-14 황재연 신규한 구조의 액상 내용물 내장 용기

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422569A1 (fr) * 1978-04-14 1979-11-09 Roussel Uclaf Distributeur de liquide sterile
DE3146343A1 (de) * 1981-11-23 1983-10-20 PROAQUA - PROVITA AG, 1700 Fribourg Steril verschlossener behaelter und verfahren zu seiner herstellung
US4414172A (en) * 1982-05-21 1983-11-08 Filtertek, Inc. Process and apparatus for sealing a plurality of filter elements
WO1990005110A1 (en) * 1988-11-03 1990-05-17 Eye Research Institute Of Retina Foundation Filter bottle
EP0401022A1 (de) * 1989-06-01 1990-12-05 Pall Corporation Vorrichtung zur injektionsfreien Verabreichung und Dosierung einer Flüssigkeit
FR2678905A1 (fr) * 1991-07-10 1993-01-15 Kerplas Snc Embout goutte a goutte.

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422569A1 (fr) * 1978-04-14 1979-11-09 Roussel Uclaf Distributeur de liquide sterile
DE3146343A1 (de) * 1981-11-23 1983-10-20 PROAQUA - PROVITA AG, 1700 Fribourg Steril verschlossener behaelter und verfahren zu seiner herstellung
US4414172A (en) * 1982-05-21 1983-11-08 Filtertek, Inc. Process and apparatus for sealing a plurality of filter elements
WO1990005110A1 (en) * 1988-11-03 1990-05-17 Eye Research Institute Of Retina Foundation Filter bottle
EP0401022A1 (de) * 1989-06-01 1990-12-05 Pall Corporation Vorrichtung zur injektionsfreien Verabreichung und Dosierung einer Flüssigkeit
FR2678905A1 (fr) * 1991-07-10 1993-01-15 Kerplas Snc Embout goutte a goutte.

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1245499A1 (de) * 2001-03-13 2002-10-02 Taisai Kako Co., Ltd. Schliessstruktur für ein Ausgabebehälter
US6672479B2 (en) 2001-03-13 2004-01-06 Taisai Kako Co., Ltd./Nihon Tenganyaku Closing structure of a dispensing container
DE102008001313B3 (de) * 2008-04-22 2009-06-04 Stella Kunststofftechnik Gmbh Tropfkappe
DE102008001313B9 (de) * 2008-04-22 2009-11-12 Stella Kunststofftechnik Gmbh Tropfkappe
US9983151B2 (en) 2014-05-08 2018-05-29 Lawrence Livermore National Security, Llc Ultralow-dose, feedback imaging with laser-Compton X-ray and laser-Compton gamma ray sources
CN106516397A (zh) * 2016-08-30 2017-03-22 嘉兴市腾翔塑业有限公司 液态化妆品出液器

Also Published As

Publication number Publication date
FR2678905B1 (fr) 1995-01-27
FR2678905A1 (fr) 1993-01-15

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