EP0600869A4 - Synthetische peptide zur abbildung von arterien. - Google Patents

Synthetische peptide zur abbildung von arterien.

Info

Publication number
EP0600869A4
EP0600869A4 EP19910910995 EP91910995A EP0600869A4 EP 0600869 A4 EP0600869 A4 EP 0600869A4 EP 19910910995 EP19910910995 EP 19910910995 EP 91910995 A EP91910995 A EP 91910995A EP 0600869 A4 EP0600869 A4 EP 0600869A4
Authority
EP
European Patent Office
Prior art keywords
synthetic peptides
arterial imaging
arterial
imaging
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910910995
Other languages
English (en)
French (fr)
Other versions
EP0600869A1 (de
Inventor
Robert S Lees
Ann M Lees
Allan Fischman
Ing-Lung Shih
Mark A Findeis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
New England Deaconess Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New England Deaconess Hospital filed Critical New England Deaconess Hospital
Publication of EP0600869A4 publication Critical patent/EP0600869A4/de
Publication of EP0600869A1 publication Critical patent/EP0600869A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Optics & Photonics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Radiology & Medical Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP91910995A 1990-05-03 1991-05-02 Synthetische peptide zur abbildung von arterien Withdrawn EP0600869A1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US51821590A 1990-05-03 1990-05-03
US51814290A 1990-05-03 1990-05-03
US518142 1990-05-03
PCT/US1991/003026 WO1991016919A1 (en) 1990-05-03 1991-05-02 Synthetic peptides for arterial imaging
US518215 1995-08-23

Publications (2)

Publication Number Publication Date
EP0600869A4 true EP0600869A4 (de) 1993-03-22
EP0600869A1 EP0600869A1 (de) 1994-06-15

Family

ID=27059361

Family Applications (1)

Application Number Title Priority Date Filing Date
EP91910995A Withdrawn EP0600869A1 (de) 1990-05-03 1991-05-02 Synthetische peptide zur abbildung von arterien

Country Status (5)

Country Link
EP (1) EP0600869A1 (de)
JP (1) JPH05507276A (de)
AU (1) AU663291B2 (de)
CA (1) CA2080493A1 (de)
WO (1) WO1991016919A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972890A (en) * 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US5726153A (en) * 1988-05-02 1998-03-10 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US5997844A (en) * 1991-02-08 1999-12-07 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
JPH07504902A (ja) * 1992-03-13 1995-06-01 ダイアタイド・インコーポレイテッド 炎症造影用のテクネチウム−９９ｍ標識ペプチド
US5733549A (en) * 1992-08-14 1998-03-31 Shino-Test Corporation Peptides including amino acid sequences selected from lipoprotein (a) and apolipoprotein (a), antibodies recognizing these amino acid sequences, and methods of determination using these antibodies
US5605671A (en) * 1992-10-05 1997-02-25 The Regents Of The University Of Michigan Radiolabeled neutrophil activating peptides for imaging
US5413778A (en) * 1992-10-05 1995-05-09 The Regents Of The University Of Michigan Labelled monocyte chemoattractant protein material and medical uses thereof
WO1994009128A1 (en) * 1992-10-22 1994-04-28 Mallinckrodt Medical, Inc. Therapeutic treatment for inhibiting vascular restenosis
DE4301871A1 (de) * 1993-01-13 1994-07-14 Diagnostikforschung Inst Neue Mittel zur Diagnose von Gefäßerkrankungen
DE4425778A1 (de) * 1994-07-13 1996-01-18 Diagnostikforschung Inst Komplexverbindungen zur Diagnose von Gefäßerkrankungen
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
JP2001505539A (ja) * 1996-08-07 2001-04-24 プロテイン・スペシャルティーズ，リミテッド エラスチン及び他の線維状タンパク質由来の自己整列ペプチド
US6632923B1 (en) 1996-11-27 2003-10-14 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
ATE317264T1 (de) 1996-11-27 2006-02-15 Boston Heart Foundation Inc Neue low density lipoprotein bindende proteine und deren verwendung in der diagnostik und behandlung von atherosklerose
US6605588B1 (en) 1996-11-27 2003-08-12 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
EP1598082A4 (de) * 2003-02-27 2008-11-12 Univ Kyushu Nat Univ Corp Kontrastmittel für kernspintomografie
US8119598B2 (en) 2007-05-10 2012-02-21 Hospital For Sick Children Synthetic peptide materials for joint reconstruction, repair and cushioning
GB201102189D0 (en) * 2011-02-08 2011-03-23 King S College London Materials and methods relating to cardiovascular imaging
WO2023086771A2 (en) * 2021-11-05 2023-05-19 Trustees Of Tufts College Materials for valuable metal recovery

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0162414A2 (de) * 1984-05-15 1985-11-27 Research Corporation Amphipatische Peptide und deren pharmazeutische Zusammensetzung
WO1986004144A1 (en) * 1984-12-31 1986-07-17 International Genetic Engineering, Inc. Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
WO1989010098A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Stimulation of chemotaxis by chemotactic peptides
WO1989010760A1 (en) * 1988-05-02 1989-11-16 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1242643A (en) * 1983-08-12 1988-10-04 Eric T. Fossel Nmr imaging utilizing chemical shift reagents
US4660563A (en) * 1984-12-31 1987-04-28 Massachusetts Institute Of Technology Method and means for detection of arterial lesions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0162414A2 (de) * 1984-05-15 1985-11-27 Research Corporation Amphipatische Peptide und deren pharmazeutische Zusammensetzung
WO1986004144A1 (en) * 1984-12-31 1986-07-17 International Genetic Engineering, Inc. Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
WO1989010098A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Stimulation of chemotaxis by chemotactic peptides
WO1989010760A1 (en) * 1988-05-02 1989-11-16 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF CELL BIOLOGY vol. 107, no. 5, November 1988, NEW YORK,USA pages 1987 - 1993 BLOOD ET AL 'IDENTIFICATION OF A TUMOR CELL RECEPTOR FOR VGVAPG,AN ELASTIN-DERIVED CHEMOTACTIC PEPTIDE' *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES,USA vol. 87, February 1990, WASHINGTON D.C.,USA pages 1436 - 1440 SHIH ET AL 'FOCAL ACCUMULATION OF AN APOLIPOPROTEIN B-BASED SYNTHETIC OLIGOPEPTIDE IN THE HEALING RABBIT ARTERIAL WALL' *
See also references of WO9116919A1 *

Also Published As

Publication number Publication date
EP0600869A1 (de) 1994-06-15
CA2080493A1 (en) 1991-11-04
WO1991016919A1 (en) 1991-11-14
AU7992891A (en) 1991-11-27
AU663291B2 (en) 1995-10-05
JPH05507276A (ja) 1993-10-21

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19921019

AK Designated contracting states

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Effective date: 19970113

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18D Application deemed to be withdrawn

Effective date: 19990705