EP0600869A4 - Synthetic peptides for arterial imaging. - Google Patents

Synthetic peptides for arterial imaging.

Info

Publication number
EP0600869A4
EP0600869A4 EP19910910995 EP91910995A EP0600869A4 EP 0600869 A4 EP0600869 A4 EP 0600869A4 EP 19910910995 EP19910910995 EP 19910910995 EP 91910995 A EP91910995 A EP 91910995A EP 0600869 A4 EP0600869 A4 EP 0600869A4
Authority
EP
European Patent Office
Prior art keywords
synthetic peptides
arterial imaging
arterial
imaging
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910910995
Other languages
German (de)
French (fr)
Other versions
EP0600869A1 (en
Inventor
Robert S Lees
Ann M Lees
Allan Fischman
Ing-Lung Shih
Mark A Findeis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
New England Deaconess Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New England Deaconess Hospital filed Critical New England Deaconess Hospital
Publication of EP0600869A4 publication Critical patent/EP0600869A4/en
Publication of EP0600869A1 publication Critical patent/EP0600869A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
EP91910995A 1990-05-03 1991-05-02 Synthetic peptides for arterial imaging Withdrawn EP0600869A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US51814290A 1990-05-03 1990-05-03
US51821590A 1990-05-03 1990-05-03
US518142 1990-05-03
PCT/US1991/003026 WO1991016919A1 (en) 1990-05-03 1991-05-02 Synthetic peptides for arterial imaging
US518215 1995-08-23

Publications (2)

Publication Number Publication Date
EP0600869A4 true EP0600869A4 (en) 1993-03-22
EP0600869A1 EP0600869A1 (en) 1994-06-15

Family

ID=27059361

Family Applications (1)

Application Number Title Priority Date Filing Date
EP91910995A Withdrawn EP0600869A1 (en) 1990-05-03 1991-05-02 Synthetic peptides for arterial imaging

Country Status (5)

Country Link
EP (1) EP0600869A1 (en)
JP (1) JPH05507276A (en)
AU (1) AU663291B2 (en)
CA (1) CA2080493A1 (en)
WO (1) WO1991016919A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726153A (en) * 1988-05-02 1998-03-10 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US5972890A (en) * 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5997844A (en) * 1991-02-08 1999-12-07 Diatide, Inc. Technetium-99m labeled peptides for imaging
WO1993017719A1 (en) * 1992-03-13 1993-09-16 Diatech, Inc. TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING INFLAMMATION
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
WO1994004563A1 (en) * 1992-08-14 1994-03-03 Shino-Test Corporation PEPTIDES CONTAINING RESPECTIVE AMINO ACID SEQUENCES SELECTED FROM AMONG THOSE OF LIPOPROTEIN(a) AND APOLIPOPROTEIN(a), ANTIBODIES RESPECTIVELY RECOGNIZING THESE AMINO ACID SEQUENCES, AND METHOD OF ASSAYING WITH THESE ANTIBODIES
US5605671A (en) * 1992-10-05 1997-02-25 The Regents Of The University Of Michigan Radiolabeled neutrophil activating peptides for imaging
US5413778A (en) * 1992-10-05 1995-05-09 The Regents Of The University Of Michigan Labelled monocyte chemoattractant protein material and medical uses thereof
AU5537994A (en) * 1992-10-22 1994-05-09 Mallinckrodt Medical, Inc. Therapeutic treatment for inhibiting vascular restenosis
DE4301871A1 (en) * 1993-01-13 1994-07-14 Diagnostikforschung Inst New means of diagnosing vascular diseases
DE4425778A1 (en) * 1994-07-13 1996-01-18 Diagnostikforschung Inst Complex compounds for the diagnosis of vascular diseases
US6489446B1 (en) 1996-08-07 2002-12-03 Hsc Research And Development Limited Partnership Self-aligning peptides modeled on human elastin and other fibrous proteins
WO1998005685A2 (en) * 1996-08-07 1998-02-12 Protein Specialties, Ltd. Self-aligning peptides derived from elastin and other fibrous proteins
US6605588B1 (en) 1996-11-27 2003-08-12 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
US6632923B1 (en) 1996-11-27 2003-10-14 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
US6355451B1 (en) 1996-11-27 2002-03-12 Boston Heart Foundation, Inc. Low density lipoprotein binding proteins and their use in diagnosing and treating atherosclerosis
US7368099B2 (en) * 2003-02-27 2008-05-06 Kyushu University, National University Corporation MRI contrast agents
AU2008251900A1 (en) 2007-05-10 2008-11-20 Elastin Specialties, Inc. Synthetic peptide materials for joint reconstruction, repair and cushioning
GB201102189D0 (en) * 2011-02-08 2011-03-23 King S College London Materials and methods relating to cardiovascular imaging
WO2023086771A2 (en) * 2021-11-05 2023-05-19 Trustees Of Tufts College Materials for valuable metal recovery

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0162414A2 (en) * 1984-05-15 1985-11-27 Research Corporation Amphipathic peptides and pharmaceutical compositions containing same
WO1986004144A1 (en) * 1984-12-31 1986-07-17 International Genetic Engineering, Inc. Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
WO1989010098A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Stimulation of chemotaxis by chemotactic peptides
WO1989010760A1 (en) * 1988-05-02 1989-11-16 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1242643A (en) * 1983-08-12 1988-10-04 Eric T. Fossel Nmr imaging utilizing chemical shift reagents
US4660563A (en) * 1984-12-31 1987-04-28 Massachusetts Institute Of Technology Method and means for detection of arterial lesions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0162414A2 (en) * 1984-05-15 1985-11-27 Research Corporation Amphipathic peptides and pharmaceutical compositions containing same
WO1986004144A1 (en) * 1984-12-31 1986-07-17 International Genetic Engineering, Inc. Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
WO1989010098A1 (en) * 1988-04-21 1989-11-02 Uab Research Foundation Stimulation of chemotaxis by chemotactic peptides
WO1989010760A1 (en) * 1988-05-02 1989-11-16 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF CELL BIOLOGY vol. 107, no. 5, November 1988, NEW YORK,USA pages 1987 - 1993 BLOOD ET AL 'IDENTIFICATION OF A TUMOR CELL RECEPTOR FOR VGVAPG,AN ELASTIN-DERIVED CHEMOTACTIC PEPTIDE' *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES,USA vol. 87, February 1990, WASHINGTON D.C.,USA pages 1436 - 1440 SHIH ET AL 'FOCAL ACCUMULATION OF AN APOLIPOPROTEIN B-BASED SYNTHETIC OLIGOPEPTIDE IN THE HEALING RABBIT ARTERIAL WALL' *
See also references of WO9116919A1 *

Also Published As

Publication number Publication date
JPH05507276A (en) 1993-10-21
CA2080493A1 (en) 1991-11-04
AU7992891A (en) 1991-11-27
EP0600869A1 (en) 1994-06-15
WO1991016919A1 (en) 1991-11-14
AU663291B2 (en) 1995-10-05

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19921019

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

17Q First examination report despatched

Effective date: 19970113

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19990705