EP0585383A4 - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
EP0585383A4
EP0585383A4 EP9292913103A EP92913103A EP0585383A4 EP 0585383 A4 EP0585383 A4 EP 0585383A4 EP 9292913103 A EP9292913103 A EP 9292913103A EP 92913103 A EP92913103 A EP 92913103A EP 0585383 A4 EP0585383 A4 EP 0585383A4
Authority
EP
European Patent Office
Prior art keywords
chemical compounds
compounds
chemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP9292913103A
Other versions
EP0585383A1 (en
Inventor
Gerald Robert Girard
David Taylor Hill
Joseph Weinstock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0585383A1 publication Critical patent/EP0585383A1/en
Publication of EP0585383A4 publication Critical patent/EP0585383A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EP9292913103A 1991-05-15 1992-05-14 Chemical compounds Withdrawn EP0585383A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919110532A GB9110532D0 (en) 1991-05-15 1991-05-15 Chemical compounds
GB91105320 1991-05-15

Publications (2)

Publication Number Publication Date
EP0585383A1 EP0585383A1 (en) 1994-03-09
EP0585383A4 true EP0585383A4 (en) 1994-08-17

Family

ID=10695047

Family Applications (1)

Application Number Title Priority Date Filing Date
EP9292913103A Withdrawn EP0585383A4 (en) 1991-05-15 1992-05-14 Chemical compounds

Country Status (11)

Country Link
EP (1) EP0585383A4 (en)
JP (1) JPH06507899A (en)
AU (1) AU2156192A (en)
GB (1) GB9110532D0 (en)
IE (1) IE921539A1 (en)
MX (1) MX9202262A (en)
NZ (1) NZ242734A (en)
PT (1) PT100491A (en)
TW (1) TW211010B (en)
WO (1) WO1992020651A2 (en)
ZA (1) ZA923496B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395847A (en) * 1993-12-02 1995-03-07 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
KR100587187B1 (en) * 1997-10-29 2006-10-24 론자 아게 Process for the preparation of formylimidazoles
KR100567183B1 (en) * 1997-11-14 2006-06-13 론자 아게 How to prepare formyl imidazole
JP2000053651A (en) * 1998-06-18 2000-02-22 Lonza Ag Production of formylimidazoles
SE9903028D0 (en) 1999-08-27 1999-08-27 Astra Ab New use
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
RU2453536C2 (en) * 2007-10-22 2012-06-20 Оркид Рисерч Лабораториз Лимитед Histone deacetylase inhibitors
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (en) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド Guanylate cyclase receptor agonists in combination with other drugs
RS65632B1 (en) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-pure agonists of guanylate cyclase c, method of making and using same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10075018I2 (en) * 1989-06-14 2001-08-09 Smithkline Beecham Corp Imidazoalkenoic acid.
AU640417B2 (en) * 1989-10-25 1993-08-26 Smithkline Beecham Corporation Substituted 5-((tetrazolyl)alkenyl)imidazoles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9220651A3 *

Also Published As

Publication number Publication date
MX9202262A (en) 1992-11-01
TW211010B (en) 1993-08-11
GB9110532D0 (en) 1991-07-03
PT100491A (en) 1993-09-30
WO1992020651A3 (en) 1993-02-18
NZ242734A (en) 1995-04-27
EP0585383A1 (en) 1994-03-09
IE921539A1 (en) 1992-11-18
AU2156192A (en) 1992-12-30
WO1992020651A2 (en) 1992-11-26
JPH06507899A (en) 1994-09-08
ZA923496B (en) 1993-04-28

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19931027

AK Designated contracting states

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Designated state(s): BE CH DE FR GB IT LI NL

A4 Supplementary search report drawn up and despatched

Effective date: 19940628

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17Q First examination report despatched

Effective date: 19970428

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 19990619