EP0580094A1 - Unité de prise de sang - Google Patents
Unité de prise de sang Download PDFInfo
- Publication number
- EP0580094A1 EP0580094A1 EP93111491A EP93111491A EP0580094A1 EP 0580094 A1 EP0580094 A1 EP 0580094A1 EP 93111491 A EP93111491 A EP 93111491A EP 93111491 A EP93111491 A EP 93111491A EP 0580094 A1 EP0580094 A1 EP 0580094A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- tube
- diamond
- barrier
- container
- assembly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2205/00—General identification or selection means
- A61J2205/10—Bar codes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2205/00—General identification or selection means
- A61J2205/30—Printed labels
Definitions
- This invention relates to barrier coatings and barrier labels for providing an effective barrier against gas and water permeability for containers, especially plastic evacuated blood collection tubes.
- Such medical products that would derive a considerable benefit from improving their barrier properties include, but are not limited to, collection tubes and particularly those used for blood collection.
- Blood collection tubes require certain performance standards to be acceptable for use in medical applications. Such performance standards include the ability to maintain greater than about 90% original draw volume over a one year period, to be radiation sterilizable and to be noninterfering in tests and analysis.
- Draw volume retention depends on the existence of a partial vacuum, or reduced pressure, inside the tube. The draw volume changes in direct proportion to the change in vacuum (reduced pressure). Therefore, draw volume retention is dependent on good vacuum retention.
- Radiation sterilizable means that after the tube is exposed to certain levels of radiation in the sterilization process, there is substantially no change in optical or mechanical and functional properties.
- Noninterference in performance of a tube's specifications means that the materials of the tube, such as glass or plastic materials do not interfere with testing and analysis that is typically performed on blood in the tube. Such tests include but are not limited to, hematology, blood chemistry, blood typing, toxicology analysis and therapeutic drug monitoring. Furthermore, the tube must be capable of being subjected to automated machinery such as centrifuges.
- the present invention is a plastic composite container coated with a barrier composition or barrier label disposed over an outer surface of the composite container. That is, a barrier composition is coated over the previously formed plastic container or a barrier label coated with a barrier composition is disposed over the outer surface of the composite container.
- a barrier composition or barrier label improves the barrier properties of plastic containers, does not obscure the contents of the plastic containers and extends the shelf-life of plastic containers, especially plastic evacuated blood collection devices.
- a desirable barrier composition which can be disposed over a plastic container or a barrier label preferably comprises a diamond composition.
- a diamond composition may be applied either to an interior surface portion or to an exterior surface portion of the container or label.
- the barrier label may be placed or formed around the container and then adhered to the container by methods such as, but not limited to, an adhesive layer, heating the barrier label and container to a temperature sufficient to cause the barrier label to heat-shrink onto the container or by expanding the container into the barrier label by blow molding.
- the barrier label of the present invention is a polymer film with a diamond composition coating.
- the diamond composition provides a transparent, translucent or colorless appearance and may have printed matter applied thereon.
- Plastic tubes or barrier labels coated with the diamond composition are able to maintain far better vacuum retention and draw volume retention than previous tubes comprised of polymer compositions and blends thereof without a barrier coating or label.
- the coated or labeled tube's water barrier properties would be significantly improved since diamond coatings are substantially non-polar. Notably is the clarity of the diamond composition, its durability to substantially withstand resistance to impact, abrasion and scratches.
- Suitable films to be coated for use as barrier labels according to the present invention include, but are not limited to polypropylene films, low and high density polyethylene films and polyvinylchloride films.
- Printing may be placed on the barrier composition or label which is to be used on the container of interest.
- a product identification, bar code, brand name, company logo, lot number, expiration date and other data and information may all be included on the label surface.
- a matte finish or a corona discharged surface may be developed on the outer surface of the barrier composition so as to make the surface appropriate for writing additional information on the label.
- another pressure sensitive adhesive label may be placed over the outer surface of the barrier label so as to accommodate various hospital over-labels, for example.
- FIG. 1 is a perspective view of a typical blood collection tube with a stopper.
- FIG. 2 is a longitudinal sectional view of the tube of FIG. 1 taken along line 2-2.
- FIG. 3 is a longitudinal sectional view of a tube-shaped container similar to the tube of FIG. 1 without a stopper.
- FIG. 4 is a longitudinal sectional view of a tube-shaped container similar to the tube of FIG. 1 with a stopper.
- FIGS. 1 and 2 show a typical blood collection tube 10 , having an open end 16 , a closed end 18 and stopper 14 which includes a lower annular portion or skirt 15 which extends into and presses against the inside walls 12 of the tube for maintaining stopper 14 in place.
- FIG. 2 schematically illustrates that there are three mechanisms for a change in vacuum in a blood collection tube: (A) gas permeation through the stopper material; (B) gas permeation through the tube material and (C) leak at the closure-tube interface. Therefore, when there is substantially no gas permeation and no leak, there is good vacuum retention and good draw volume retention.
- FIG. 3 shows the preferred embodiment of the invention, a plastic tube coated with a diamond composition or covered by a diamond coated barrier label.
- the preferred embodiment includes many components which are substantially identical to the components of FIGS. 1 and 2. Accordingly, similar components performing similar functions will be numbered identically to those components of FIGS. 1 and 2, except that a suffix "a" will be used to identify those components in FIG. 3.
- collection tube assembly 20 comprises a plastic tube 10a , having an open end 16a and a closed end 18a .
- a coating comprising a diamond composition or diamond coated barrier label 25 extends over a substantial portion of the length of the tube which is upon the outer surface of the tube with the exception of open end 16a and closed end 18a thereof.
- FIG. 4 illustrates an alternate embodiment of the invention, wherein collection tube assembly 40 comprises stopper 48 in place for closing open end 41 of tube 42 .
- stopper 48 includes an annular upper portion 50 which extends over the top edge of tube 42 .
- Stopper 48 includes a lower annular portion or skirt 49 which extends into and presses against the inside walls of tube 42 for maintaining stopper 48 in place and also, defines a well 52 which, in turn, defines a septum portion 53 for receiving a cannula therethrough.
- the user once receiving a container such as that shown in FIG. 4 with a sample contained therein, may insert a cannula through septum 53 for receiving part or all of the contents in tube 42 to perform various tests on a sample.
- FIG. 4 differs from the embodiment in FIG. 3 in that the tube may be evacuated with the simultaneous placement of stopper 48 therein after the application of a diamond coating or diamond coated barrier label 45 thereover the tube. Alternatively, the diamond coating or diamond coated barrier label may be applied to the tube before it has been evacuated.
- An alternate embodiment of the invention also includes a coating or label incorporating both the upper portion of the stopper, as well as the entire container tube. Such an embodiment may be utilized, for example, for sealing the container with the stopper in place. Once a sample has been placed in the tube, the sample cannot be tampered with by removal of the stopper. Additionally, serrations could be included at the tube, stopper interface. The serrations may be registered so that it can be determined if the sealed container has been tampered with.
- tubes may contain reagents in the form of additives or coatings on the inner wall of the tube.
- a coating comprising a diamond composition forms a clear or translucent barrier. Therefore, the contents of a plastic tube coated with a coating comprising a diamond composition are visable to the observer at the same time identifying information may be displayed over the diamond film after it is applied to the plastic tube.
- a coating comprising a diamond composition may be formed on a substrate by radio frequency discharge, direct or dual ion beam deposition, sputtering or plasma chemical vapor depositions as described in U.S. Patent Nos. 4,698,256, 4,809,876, 4,992,298 and 5,055,318, the disclosures of which are herein incorporated by reference.
- the coating of the present invention is preferably a diamond composition comprising carbon having a major proportion of sp3 tetrahedral bonding and a minor proportion of sp2 bonds.
- the diamond compositions of the present invention may consist of carbon atoms bonded in a dense chemical structure similar to that in a diamond, but without a long range crystal order.
- the diamond coating is applied to the plastic container or to a barrier film by a dual ion beam ballistic alloy process.
- a plastic blood collection tube coated with the diamond composition or covered with a diamond coated barrier label may effectively be used in such applications as routine chemical analysis, biological inertness, hematology, blood chemistry, blood typing, toxicology analysis or therapeutic drug monitoring and other clinical tests involving body fluids.
- the diamond composition is also coated on the inner surface of the plastic blood collection tube, the diamond coating may be hemorepellent and/or have characteristics of a clot activator.
- plastic composite container is evacuated or not evacuated in accordance with this invention.
- the presence of a barrier composition or barrier label on the outer surface of the container has the effect of maintaining the general integrity of the container holding a sample so that it may be properly disposed of without any contamination to the user. Notably is the clarity of the barrier composition or barrier label and their abrasion and scratch resistance.
- the diamond coatings or blends thereof used in accordance with this disclosure may contain conventional additives and ingredients which do not adversely affect the properties of articles made therefrom.
- the barrier label is desirably a film coated with a high barrier performance material such as a diamond composition.
- Preferred film materials include, but are not limited to, polymeric substrate resins.
- Polymeric substrate resins include, but are not limited to polyamide, polyolefin and polyester.
- Polyamide includes but is not limited to, biaxial oriented nylon, aromatic amorphous polyamide, polyvinyl chloride and mixtures thereof.
- Polyolefin includes, but is not limited to biaxial oriented polypropylene, low density polyethylene, polychlorotrifluoroethylene and mixtures thereof.
- Polyester includes, but is not limited to, polyethylene terephthalate, polyethylene naphthalate, polyethylene isophthalate and mixtures thereof.
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Analytical Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91886492A | 1992-07-22 | 1992-07-22 | |
US918864 | 1992-07-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0580094A1 true EP0580094A1 (fr) | 1994-01-26 |
EP0580094B1 EP0580094B1 (fr) | 1996-10-16 |
Family
ID=25441088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19930111491 Expired - Lifetime EP0580094B1 (fr) | 1992-07-22 | 1993-07-17 | Unité de prise de sang |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0580094B1 (fr) |
JP (1) | JP2504915B2 (fr) |
AU (1) | AU664287B2 (fr) |
CA (1) | CA2100275A1 (fr) |
DE (1) | DE69305443T2 (fr) |
ES (1) | ES2093331T3 (fr) |
Cited By (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0603717A2 (fr) * | 1992-12-18 | 1994-06-29 | Becton, Dickinson and Company | Etiquette à propiété barrière |
GB2287473A (en) * | 1994-03-15 | 1995-09-20 | Dr Joseph Franks | Diamond coated polymer devices for biomedical applications |
AT402365B (de) * | 1993-12-21 | 1997-04-25 | Greiner & Soehne C A | Aufnahmevorrichtung mit einem zylinderförmigen behälter und blutprobenentnahmeröhrchen mit einer derartigen aufnahmevorrichtung |
EP0773166A1 (fr) * | 1994-08-11 | 1997-05-14 | Kirin Beer Kabushiki Kaisha | Recipient plastique revetu d'un film de carbone |
EP0876821A2 (fr) * | 1997-05-02 | 1998-11-11 | Howmedica International Inc. | Procédé pour améliorer le taux de friction ou démarrage et pendant le mouvement uniforme de polyuréthanes mous flexibles |
US5871700A (en) * | 1993-12-21 | 1999-02-16 | C.A. Greiner & Sohne Gesellschaft M.B.H. | Holding device with a cylindrical container and blood sampling tube with such a holding device |
US6979307B2 (en) | 1997-06-24 | 2005-12-27 | Cascade Medical Enterprises Llc | Systems and methods for preparing autologous fibrin glue |
US7745106B2 (en) | 1997-06-24 | 2010-06-29 | Cascade Medical Enterprises, Llc | Methods and devices for separating liquid components |
US20110123414A1 (en) * | 2001-06-18 | 2011-05-26 | Becton, Dickinson And Company | Multilayer containers |
US7985188B2 (en) | 2009-05-13 | 2011-07-26 | Cv Holdings Llc | Vessel, coating, inspection and processing apparatus |
US8512796B2 (en) | 2009-05-13 | 2013-08-20 | Si02 Medical Products, Inc. | Vessel inspection apparatus and methods |
US9272095B2 (en) | 2011-04-01 | 2016-03-01 | Sio2 Medical Products, Inc. | Vessels, contact surfaces, and coating and inspection apparatus and methods |
US9458536B2 (en) | 2009-07-02 | 2016-10-04 | Sio2 Medical Products, Inc. | PECVD coating methods for capped syringes, cartridges and other articles |
US9545360B2 (en) | 2009-05-13 | 2017-01-17 | Sio2 Medical Products, Inc. | Saccharide protective coating for pharmaceutical package |
US9554968B2 (en) | 2013-03-11 | 2017-01-31 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging |
US9662450B2 (en) | 2013-03-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Plasma or CVD pre-treatment for lubricated pharmaceutical package, coating process and apparatus |
US9664626B2 (en) | 2012-11-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Coating inspection method |
US9764093B2 (en) | 2012-11-30 | 2017-09-19 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
US9863042B2 (en) | 2013-03-15 | 2018-01-09 | Sio2 Medical Products, Inc. | PECVD lubricity vessel coating, coating process and apparatus providing different power levels in two phases |
US9878101B2 (en) | 2010-11-12 | 2018-01-30 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
US9903782B2 (en) | 2012-11-16 | 2018-02-27 | Sio2 Medical Products, Inc. | Method and apparatus for detecting rapid barrier coating integrity characteristics |
US9937099B2 (en) | 2013-03-11 | 2018-04-10 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging with low oxygen transmission rate |
US10189603B2 (en) | 2011-11-11 | 2019-01-29 | Sio2 Medical Products, Inc. | Passivation, pH protective or lubricity coating for pharmaceutical package, coating process and apparatus |
US10201660B2 (en) | 2012-11-30 | 2019-02-12 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition on medical syringes, cartridges, and the like |
US11066745B2 (en) | 2014-03-28 | 2021-07-20 | Sio2 Medical Products, Inc. | Antistatic coatings for plastic vessels |
US11077233B2 (en) | 2015-08-18 | 2021-08-03 | Sio2 Medical Products, Inc. | Pharmaceutical and other packaging with low oxygen transmission rate |
US11116695B2 (en) | 2011-11-11 | 2021-09-14 | Sio2 Medical Products, Inc. | Blood sample collection tube |
US11624115B2 (en) | 2010-05-12 | 2023-04-11 | Sio2 Medical Products, Inc. | Syringe with PECVD lubrication |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6179787B1 (en) * | 1997-09-12 | 2001-01-30 | Becton Dickinson And Company | Collection container assembly |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4164320A (en) * | 1974-09-26 | 1979-08-14 | Medical Laboratory Automation, Inc. | Patient and specimen identification means and system employing same |
US4809876A (en) * | 1987-08-27 | 1989-03-07 | Aluminum Company Of America | Container body having improved gas barrier properties |
EP0409122A2 (fr) * | 1989-07-19 | 1991-01-23 | Drummond Scientific Company | Pipette de sécurité |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4783361A (en) * | 1984-09-10 | 1988-11-08 | Ovonic Synthetic Materials Company, Inc. | Coated lenses |
US5019243A (en) * | 1987-04-03 | 1991-05-28 | Mcewen James A | Apparatus for collecting blood |
-
1993
- 1993-07-12 CA CA 2100275 patent/CA2100275A1/fr not_active Abandoned
- 1993-07-15 AU AU41978/93A patent/AU664287B2/en not_active Ceased
- 1993-07-17 ES ES93111491T patent/ES2093331T3/es not_active Expired - Lifetime
- 1993-07-17 DE DE1993605443 patent/DE69305443T2/de not_active Expired - Fee Related
- 1993-07-17 EP EP19930111491 patent/EP0580094B1/fr not_active Expired - Lifetime
- 1993-07-22 JP JP5181093A patent/JP2504915B2/ja not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4164320A (en) * | 1974-09-26 | 1979-08-14 | Medical Laboratory Automation, Inc. | Patient and specimen identification means and system employing same |
US4809876A (en) * | 1987-08-27 | 1989-03-07 | Aluminum Company Of America | Container body having improved gas barrier properties |
EP0409122A2 (fr) * | 1989-07-19 | 1991-01-23 | Drummond Scientific Company | Pipette de sécurité |
Cited By (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0603717A2 (fr) * | 1992-12-18 | 1994-06-29 | Becton, Dickinson and Company | Etiquette à propiété barrière |
EP0603717A3 (fr) * | 1992-12-18 | 1994-12-07 | Becton Dickinson Co | Etiquette à propiété barrière. |
AT402365B (de) * | 1993-12-21 | 1997-04-25 | Greiner & Soehne C A | Aufnahmevorrichtung mit einem zylinderförmigen behälter und blutprobenentnahmeröhrchen mit einer derartigen aufnahmevorrichtung |
US5871700A (en) * | 1993-12-21 | 1999-02-16 | C.A. Greiner & Sohne Gesellschaft M.B.H. | Holding device with a cylindrical container and blood sampling tube with such a holding device |
GB2287473A (en) * | 1994-03-15 | 1995-09-20 | Dr Joseph Franks | Diamond coated polymer devices for biomedical applications |
GB2287473B (en) * | 1994-03-15 | 1998-01-07 | Dr Joseph Franks | Coated polymer devices for biomedical applications |
EP0773166A1 (fr) * | 1994-08-11 | 1997-05-14 | Kirin Beer Kabushiki Kaisha | Recipient plastique revetu d'un film de carbone |
EP0773166A4 (fr) * | 1994-08-11 | 1999-08-25 | Kirin Brewery | Recipient plastique revetu d'un film de carbone |
EP1254845A2 (fr) * | 1994-08-11 | 2002-11-06 | Kirin Beer Kabushiki Kaisha | Recipient plastique revetu d'un film de carbone |
EP1254845A3 (fr) * | 1994-08-11 | 2006-02-15 | Kirin Beer Kabushiki Kaisha | Recipient plastique revetu d'un film de carbone |
EP0876821A2 (fr) * | 1997-05-02 | 1998-11-11 | Howmedica International Inc. | Procédé pour améliorer le taux de friction ou démarrage et pendant le mouvement uniforme de polyuréthanes mous flexibles |
EP0876821A3 (fr) * | 1997-05-02 | 2000-02-02 | Howmedica International Inc. | Procédé pour améliorer le taux de friction ou démarrage et pendant le mouvement uniforme de polyuréthanes mous flexibles |
US6979307B2 (en) | 1997-06-24 | 2005-12-27 | Cascade Medical Enterprises Llc | Systems and methods for preparing autologous fibrin glue |
US7745106B2 (en) | 1997-06-24 | 2010-06-29 | Cascade Medical Enterprises, Llc | Methods and devices for separating liquid components |
US20110123414A1 (en) * | 2001-06-18 | 2011-05-26 | Becton, Dickinson And Company | Multilayer containers |
US9283704B2 (en) * | 2001-06-18 | 2016-03-15 | Becton, Dickinson And Company | Multilayer containers |
US7985188B2 (en) | 2009-05-13 | 2011-07-26 | Cv Holdings Llc | Vessel, coating, inspection and processing apparatus |
US8512796B2 (en) | 2009-05-13 | 2013-08-20 | Si02 Medical Products, Inc. | Vessel inspection apparatus and methods |
US8834954B2 (en) | 2009-05-13 | 2014-09-16 | Sio2 Medical Products, Inc. | Vessel inspection apparatus and methods |
US10390744B2 (en) | 2009-05-13 | 2019-08-27 | Sio2 Medical Products, Inc. | Syringe with PECVD lubricity layer, apparatus and method for transporting a vessel to and from a PECVD processing station, and double wall plastic vessel |
US9545360B2 (en) | 2009-05-13 | 2017-01-17 | Sio2 Medical Products, Inc. | Saccharide protective coating for pharmaceutical package |
US10537273B2 (en) | 2009-05-13 | 2020-01-21 | Sio2 Medical Products, Inc. | Syringe with PECVD lubricity layer |
US9572526B2 (en) | 2009-05-13 | 2017-02-21 | Sio2 Medical Products, Inc. | Apparatus and method for transporting a vessel to and from a PECVD processing station |
US9458536B2 (en) | 2009-07-02 | 2016-10-04 | Sio2 Medical Products, Inc. | PECVD coating methods for capped syringes, cartridges and other articles |
US11624115B2 (en) | 2010-05-12 | 2023-04-11 | Sio2 Medical Products, Inc. | Syringe with PECVD lubrication |
US9878101B2 (en) | 2010-11-12 | 2018-01-30 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
US11123491B2 (en) | 2010-11-12 | 2021-09-21 | Sio2 Medical Products, Inc. | Cyclic olefin polymer vessels and vessel coating methods |
US9272095B2 (en) | 2011-04-01 | 2016-03-01 | Sio2 Medical Products, Inc. | Vessels, contact surfaces, and coating and inspection apparatus and methods |
US11724860B2 (en) | 2011-11-11 | 2023-08-15 | Sio2 Medical Products, Inc. | Passivation, pH protective or lubricity coating for pharmaceutical package, coating process and apparatus |
US11884446B2 (en) | 2011-11-11 | 2024-01-30 | Sio2 Medical Products, Inc. | Passivation, pH protective or lubricity coating for pharmaceutical package, coating process and apparatus |
US11148856B2 (en) | 2011-11-11 | 2021-10-19 | Sio2 Medical Products, Inc. | Passivation, pH protective or lubricity coating for pharmaceutical package, coating process and apparatus |
US10189603B2 (en) | 2011-11-11 | 2019-01-29 | Sio2 Medical Products, Inc. | Passivation, pH protective or lubricity coating for pharmaceutical package, coating process and apparatus |
US11116695B2 (en) | 2011-11-11 | 2021-09-14 | Sio2 Medical Products, Inc. | Blood sample collection tube |
US10577154B2 (en) | 2011-11-11 | 2020-03-03 | Sio2 Medical Products, Inc. | Passivation, pH protective or lubricity coating for pharmaceutical package, coating process and apparatus |
US9664626B2 (en) | 2012-11-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Coating inspection method |
US9903782B2 (en) | 2012-11-16 | 2018-02-27 | Sio2 Medical Products, Inc. | Method and apparatus for detecting rapid barrier coating integrity characteristics |
US9764093B2 (en) | 2012-11-30 | 2017-09-19 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
US10201660B2 (en) | 2012-11-30 | 2019-02-12 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition on medical syringes, cartridges, and the like |
US10363370B2 (en) | 2012-11-30 | 2019-07-30 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
US11406765B2 (en) | 2012-11-30 | 2022-08-09 | Sio2 Medical Products, Inc. | Controlling the uniformity of PECVD deposition |
US9662450B2 (en) | 2013-03-01 | 2017-05-30 | Sio2 Medical Products, Inc. | Plasma or CVD pre-treatment for lubricated pharmaceutical package, coating process and apparatus |
US11344473B2 (en) | 2013-03-11 | 2022-05-31 | SiO2Medical Products, Inc. | Coated packaging |
US10016338B2 (en) | 2013-03-11 | 2018-07-10 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging |
US9937099B2 (en) | 2013-03-11 | 2018-04-10 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging with low oxygen transmission rate |
US11298293B2 (en) | 2013-03-11 | 2022-04-12 | Sio2 Medical Products, Inc. | PECVD coated pharmaceutical packaging |
US10537494B2 (en) | 2013-03-11 | 2020-01-21 | Sio2 Medical Products, Inc. | Trilayer coated blood collection tube with low oxygen transmission rate |
US11684546B2 (en) | 2013-03-11 | 2023-06-27 | Sio2 Medical Products, Inc. | PECVD coated pharmaceutical packaging |
US10912714B2 (en) | 2013-03-11 | 2021-02-09 | Sio2 Medical Products, Inc. | PECVD coated pharmaceutical packaging |
US9554968B2 (en) | 2013-03-11 | 2017-01-31 | Sio2 Medical Products, Inc. | Trilayer coated pharmaceutical packaging |
US9863042B2 (en) | 2013-03-15 | 2018-01-09 | Sio2 Medical Products, Inc. | PECVD lubricity vessel coating, coating process and apparatus providing different power levels in two phases |
US11066745B2 (en) | 2014-03-28 | 2021-07-20 | Sio2 Medical Products, Inc. | Antistatic coatings for plastic vessels |
US11077233B2 (en) | 2015-08-18 | 2021-08-03 | Sio2 Medical Products, Inc. | Pharmaceutical and other packaging with low oxygen transmission rate |
Also Published As
Publication number | Publication date |
---|---|
ES2093331T3 (es) | 1996-12-16 |
CA2100275A1 (fr) | 1994-01-23 |
JPH06165772A (ja) | 1994-06-14 |
EP0580094B1 (fr) | 1996-10-16 |
AU4197893A (en) | 1994-01-27 |
AU664287B2 (en) | 1995-11-09 |
JP2504915B2 (ja) | 1996-06-05 |
DE69305443T2 (de) | 1997-03-06 |
DE69305443D1 (de) | 1996-11-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0580094B1 (fr) | Unité de prise de sang | |
EP0571116A1 (fr) | Tube de prélèvement du sang | |
AU669754B2 (en) | Barrier coating | |
EP0603717B1 (fr) | Etiquette à propiété barrière | |
US5716683A (en) | Blood collection tube assembly | |
US5000804A (en) | Process for making body fluid sample collection tube composite | |
EP0789092B1 (fr) | Tube de prélèvement du sang | |
EP0814114A1 (fr) | Couche barrière | |
EP0535810B1 (fr) | Tube pour le prélèvement du sang | |
US5683771A (en) | Blood collection tube assembly | |
US5955161A (en) | Blood collection tube assembly | |
AU7936601A (en) | Medical article having blood-contacting surface | |
AU681530B2 (en) | Container and related sample collection tube | |
EP1382394A1 (fr) | Ensemble des tubes de prélèvement d'échantillons avec différenciation des tubes | |
KR900004140B1 (ko) | 체액 수집용 관 조립체 | |
KR102281912B1 (ko) | 가스 장벽 코팅 위에 내부 탑 코팅을 지니는 배양 용기 및 관련 방법 | |
JPS61128944A (ja) | 減圧採血管 | |
CA2179231A1 (fr) | Revetement barriere | |
CA2271504A1 (fr) | Dispositif de prelevement sanguin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): BE DE ES FR GB IT SE |
|
17P | Request for examination filed |
Effective date: 19940305 |
|
17Q | First examination report despatched |
Effective date: 19950518 |
|
GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): BE DE ES FR GB IT SE |
|
ET | Fr: translation filed | ||
REF | Corresponds to: |
Ref document number: 69305443 Country of ref document: DE Date of ref document: 19961121 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2093331 Country of ref document: ES Kind code of ref document: T3 |
|
ITF | It: translation for a ep patent filed |
Owner name: ING. C. GREGORJ S.P.A. |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed | ||
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: ES Payment date: 19980720 Year of fee payment: 6 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 19990707 Year of fee payment: 7 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 19990718 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 19990915 Year of fee payment: 7 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20000718 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20000731 |
|
BERE | Be: lapsed |
Owner name: BECTON DICKINSON AND CY Effective date: 20000731 |
|
EUG | Se: european patent has lapsed |
Ref document number: 93111491.2 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: IF02 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20030709 Year of fee payment: 11 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20000810 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20040717 |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20040717 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES;WARNING: LAPSES OF ITALIAN PATENTS WITH EFFECTIVE DATE BEFORE 2007 MAY HAVE OCCURRED AT ANY TIME BEFORE 2007. THE CORRECT EFFECTIVE DATE MAY BE DIFFERENT FROM THE ONE RECORDED. Effective date: 20050717 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20050718 Year of fee payment: 13 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20050831 Year of fee payment: 13 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070201 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20070330 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20060731 |