EP0570335A1 - Dispositif et procédé pour mélanger un composant pulvérulent solide dans un matériau liquide - Google Patents

Dispositif et procédé pour mélanger un composant pulvérulent solide dans un matériau liquide Download PDF

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Publication number
EP0570335A1
EP0570335A1 EP93810315A EP93810315A EP0570335A1 EP 0570335 A1 EP0570335 A1 EP 0570335A1 EP 93810315 A EP93810315 A EP 93810315A EP 93810315 A EP93810315 A EP 93810315A EP 0570335 A1 EP0570335 A1 EP 0570335A1
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EP
European Patent Office
Prior art keywords
line
passed
interior
passage
container
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP93810315A
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German (de)
English (en)
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EP0570335B1 (fr
Inventor
Urs Liechti
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JetSolutions SA
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Liechti Urs
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50Mixing liquids with solids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/50Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle
    • B01F25/53Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle in which the mixture is discharged from and reintroduced into a receptacle through a recirculation tube, into which an additional component is introduced
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05Stirrers
    • B01F27/11Stirrers characterised by the configuration of the stirrers
    • B01F27/112Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades
    • B01F27/1122Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades anchor-shaped
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05Stirrers
    • B01F27/11Stirrers characterised by the configuration of the stirrers
    • B01F27/114Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections
    • B01F27/1145Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections ribbon shaped with an open space between the helical ribbon flight and the rotating axis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/23Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by the orientation or disposition of the rotor axis
    • B01F27/232Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by the orientation or disposition of the rotor axis with two or more rotation axes
    • B01F27/2322Mixers with rotary stirring devices in fixed receptacles; Kneaders characterised by the orientation or disposition of the rotor axis with two or more rotation axes with parallel axes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/85Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with two or more stirrers on separate shafts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/90Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with paddles or arms 
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/92Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with helices or screws

Definitions

  • the invention relates to a device and a method for adding a pourable component to a liquid base, namely a device according to the preamble of claim 1 and a method according to the preamble of claim 10.
  • the device and the method serve in particular to produce mixtures, such as emulsions, suspensions and the like, for example pastes, ointments, lotions, creams etc., which are used for pharmaceutical or cosmetic purposes, the mixtures produced forming the end product or even further can be processed.
  • mixtures such as emulsions, suspensions and the like, for example pastes, ointments, lotions, creams etc., which are used for pharmaceutical or cosmetic purposes, the mixtures produced forming the end product or even further can be processed.
  • the device and the method can be provided, for example, for the batch-wise emulsification of a product which has at least two immiscible components, such as water and at least one fat and / or oil, the two immiscible components preferably being at about 60 to 80 ° C temperature be warmed before mixing them together.
  • a water-in-oil emulsion can first be produced, which is cooled during the emulsification process and, during a phase transition, changes into an oil-in-water emulsion which forms the end product.
  • Devices which are known on the market and are intended for batch operation for mixing a good, in particular for adding a pourable component to a liquid base, have a double-walled container which at least has a stirrer rotatable about a vertical axis, a homogenizer and a device for introducing a cooling or heating fluid between the two walls of the container.
  • the homogenizer is used to vertically circulate the material moved by the stirrer and to reduce the emulsion droplets by shear in the production of emulsions.
  • Homogenizers which exert their shearing action by rotating tools are preferably installed in the known devices.
  • colloid mills, pin mills or dissolver disks working according to the rotor-stator principle can be inserted into the containers, one or the other homogenizer being preferred depending on the product to be manufactured.
  • an oil-in-water emulsion intended as a pharmaceutical is produced with the known devices, in which the oil is to be distributed in the form of fine droplets in the water, at least one oil is heated in a preheating container and in the liquid state with the water in the aforementioned container mixed.
  • the material formed from water and oil is then cooled with constant stirring and homogenization by a cooling fluid passed between the two walls of the container for a predetermined period of time.
  • Additional components such as, for example, at least one active pharmaceutical ingredient and / or at least one dye are added to the liquid phase in the container during the mixing and emulsification process.
  • the object of the invention is to create a device and a method which do not have the disadvantages of the known devices and methods.
  • the device should be able to be used for the production of various mixtures, for example for the production of emulsions, suspensions, gels and the like.
  • FIG. 1 shows a device for mixing a good, shown schematically, partly in vertical section, partly in a view
  • FIG. 2 shows a schematic illustration of a solids introduction device with a metering element
  • Figure 3 is a schematic representation of a solids feeding device with another dosing
  • Figure 4 is a schematic representation of part of a turbulence tube.
  • the device for mixing a good shown in FIG. 1 and designated as a whole by 1 has a container 2.
  • This is essentially rotationally symmetrical, that is to say it has a vertical axis 3, and has a double-walled wall 4, at the lower end of which a floor 5 is connected.
  • the container 2 is further provided with a cover 6 detachably connected to the wall 4, which together with the wall 4 and the bottom 5 delimits an interior space 7.
  • the bottom 5 has an outlet 8 at the lower end, which is provided with a regulating element 9 which can optionally be locked and released.
  • An anchor stirrer 10 and a spiral stirrer 11 are arranged in the interior 7 of the container 2, both of which can be rotated about their vertical axis by a common drive device 12.
  • the shafts 10a and 11a of the two stirrers 10 and 11 penetrate the cover 6 and can be driven in opposite directions by the motor 13 of the drive device 12 via a gear at speeds of, for example, 10 to 20 or 25 to 50 revolutions per minute.
  • the two agitator arms 10b and 10c of the anchor agitator 10 are adapted to the inner shape of the container 2 and have movable scrapers 13 which, when the agitator 10 is rotated, are pressed against the inner wall of the container 2 by the centrifugal force generated thereby.
  • the device 1 also has a line 14 which connects the outlet 8 to the inlet 6a provided in the cover 6. Through this line 14, at least part of the material present in the container is passed through during the mixing and emulsification process and is thereby circulated vertically.
  • the line 14 has a pump 15, an outlet valve 16 and a solids introduction device 17 arranged downstream of the pump 15 in the flow direction. The latter essentially serves to admix at least one component consisting of solid particles to a liquid base compound passed through the line 14 by means of the pump 15.
  • FIGS. 2 and 3 Two embodiments of the solids introduction device 17, designated 17a and 17b, are shown in FIGS. 2 and 3 on a larger scale and in detail. They are essentially cylindrical, that is to say they have an axis 18, and have a passage 19 through which the liquid base material or a mixture produced during the mixing or emulsification process can be passed.
  • the passage 19 is formed by a cross-sectional constriction, has an oval, for example elliptical, cross section at least over part of its length and is formed by a cavity which is rectangular in cross section, for example square 20 interrupted, the cross-sectional area perpendicular to the passage 19 is slightly larger than the cross section of the passage 19.
  • a feed line 21 opens into the cavity 20, which serves to feed a bulk material, for example a powdered medicinal product, to the liquid matrix passed through the passage 19 to mix.
  • This feed line 21 has a metering element 22 connected to the solids feeding device 17, which - as shown in FIGS. 2 and 3 - can be designed as a flap valve 22a or pinch valve 22b.
  • the solids feed device 17 has two further feed lines 23 and 24 opening into the cavity 28, through which liquid additives can be added to the mixed material passed through the solids feed device 17.
  • a turbulence tube 25 connected to the line 14 via the inlet 6a and projecting into the interior 7. This serves to homogenize the material passed through the turbulence tube 25 and to optimally distribute it in the interior 7 of the container 2.
  • the turbulence tube 25, the lower end of which is shown on a larger scale and also in detail in FIG. 4, has an elongated, sleeve-like and essentially cylindrical housing 26 which has a bottom 26a with a circular opening 26b at the lower end.
  • An axially displaceable displacement element 27 is also arranged in the interior of the housing 26. This is essentially rotationally symmetrical and has an enlarged diameter at its end 27a facing the base 26a.
  • the actuating device 28 has a manually, electrically and / or hydraulically adjustable actuating element which serves for optionally enlarging or reducing the gap width s.
  • the turbulence pipe 25 also has a baffle plate 29 arranged at the lower end, through which the material guided through the opening 26a is deflected and distributed evenly in the interior 7.
  • the device 1 has a heating and / or cooling device, not shown, with which a heating or cooling fluid can optionally be introduced into the intermediate space formed by the two wall parts of the double-walled container 2, in order to thereby heat or cool the material present in the container.
  • a batch of an oil-in-water emulsion is to be produced using a device described with reference to FIGS. 1 to 4, a batch of water is introduced into the interior 7 of the container 2 through an inlet (not shown in FIG. 1).
  • a heating fluid for example hot water and / or water vapor, is then passed through the intermediate space 5 of the wall 4 in order to heat the water present in the interior 7 of the container 2 to a temperature of, for example, 60 to 80 ° C.
  • a batch of at least one oil is heated in a preheating container to a temperature that is also 60 to 80 ° C.
  • a vacuum can be generated in container 2 in order to prevent the formation of air bubbles in the emulsion.
  • a vacuum pump used to generate the vacuum can be connected to the interior 7 of the container 2 via a connection (not shown in FIG. 1).
  • the shut-off device 9 is opened and at least part of the water present in the container 2 is passed through the line 14 by means of the conveying device 15.
  • the heated oil is mixed through the feed line 23 or 24 of the solids feed device 17 to the water passed through the passage 19.
  • the static pressure of the water jet passed through the line 14 in the cavity 20 is lower than in the other sections of the line 14 and preferably also less than the atmospheric pressure of the surroundings, so that the oil passes through the passage 19 water flowing through it is sucked in. If the device 1 is designed such that a negative pressure prevails in the interior 7 relative to the surroundings, the oil can also be sucked in by this negative pressure and conveyed into the interior 7.
  • the mixture present in the container 2 is still - through successive time intervals or continuously - passed through the line 14 so that via the feed line 21 there is at least one component consisting of solid particles, for example a powdery one , Active pharmaceutical ingredient and / or a powdery dye, these being sucked in at least in part by the negative pressure prevailing in the cavity 20.
  • solid particles for example a powdery one , Active pharmaceutical ingredient and / or a powdery dye, these being sucked in at least in part by the negative pressure prevailing in the cavity 20.
  • These solids are taken up essentially in particles. This means that the powder column, which is conveyed through line 21 and ends at one end in cavity 20, is removed in particles by the liquid passed through cavity 20.
  • This type of solids absorption has the advantage over the already known methods that the powder distributes itself relatively quickly and evenly in the material and that no agglomerates of solid particles can form during or after the powder is introduced, since these are introduced by the through the cavity 20 flowing liquid optimally wetted and distributed in this.
  • the liquid flow passed through the cavity 20 takes the form of an oval beam in cross section at.
  • the powdery component is taken up via one of the two flatter interface areas of the jet, so that the distribution of the solid particles in the liquid flowing through the cavity 20 and also the wettability of the solid particles are additionally improved.
  • the emulsion produced can finally be removed from the device 1 by opening the outlet valve 16.
  • the mixed material passed through the line 14 is circulated vertically, homogenized through the turbulence tube 25 and evenly distributed in the interior 7.
  • the conveying path of the mixed material conveyed out of the turbulence tube 25 into the interior 7 is indicated by the arrows 30 shown in FIGS. 1 and 4. Since the flow cross-section at the lower end of the turbulence tube 25 is reduced, the mixture passed through it is accelerated before it leaves the turbulence tube 25 and pressed out of the turbulence tube 25 through the gap.
  • the mixture flowing out forms an annular jet which is deflected on the plate 29, whereupon the mixture is distributed uniformly in the interior 7.
  • the strength of the homogenization depends on the gap width s, the mixture being homogenized correspondingly more strongly by reducing the gap width s.
  • the device 1 now has the further advantage over the known devices that the mix is gently homogenized - that is, without a homogenizer, which has a movable tool for generating the shear effect - so that the molecular structures of those present in the mix Components are not destroyed. Furthermore, by regulating the gap width s, the strength of the homogenization can also be set depending on the product to be manufactured and on the physical and chemical properties of the starting materials used.
  • the end product When emulsifying, the end product may also form before the mix has cooled completely. In this case, in order to prevent the emulsion particles from further shrinking, the gap width s can be increased during the subsequent cooling process, so that the mixture is practically no longer homogenized, but is only circulated vertically.
  • the emulsion or suspension particles agglomerate during the production of emulsions and suspensions, that is to say they adhere to one another, as a result of which the quality of the product to be produced is deteriorated.
  • the gap width s can be reduced, so that an emulsion or a suspension with an optimal average particle size can thereby be produced.
  • the end face of the displacement element 27 facing the gap can be provided with holes and / or grooves (not shown in FIG. 4) and / or with a cross toothing. Through such an end face, the mixing can be promoted by adjusting the gap width s and the homogenization of a mixed material passed through the turbulence tube 25 can be increased.
  • the baffle plate 29 serving for the uniform distribution of the mixed material flowing out of the turbulence tube 25 has different shapes can have.
  • it can also be curved, so that the material deflected by it is optimally distributed in the interior 7.
  • liquid additives such as preservatives, thickeners, perfumes and the like, can be sucked in during the mixing process via the feed lines 23 and 24 of the solids introduction device 17, so that no conveying devices serving to admix these substances are required.
  • the device 1 can of course also have an electronic control device in order to automatically carry out the control and / or regulating operations that are different for the mixing process.
  • the wall 4 of the container 2 can have thermal insulation and / or a pipe coil instead of the intermediate space 5, so that the cooling or heating fluid can be passed through the pipe coil.
  • an electrical heating device could also be provided, possibly with a cooling device can be combined so that the container can be cooled or heated.
  • the device can also have a cleaning device for cleaning the container in order to clean the inner wall of the container, the at least one stirrer and also the turbulence tube.
EP93810315A 1992-04-30 1993-04-29 Dispositif et procédé pour mélanger un composant pulvérulent solide dans un matériau liquide Expired - Lifetime EP0570335B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1397/92 1992-04-30
CH139792 1992-04-30

Publications (2)

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EP0570335A1 true EP0570335A1 (fr) 1993-11-18
EP0570335B1 EP0570335B1 (fr) 1995-08-23

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EP (1) EP0570335B1 (fr)
DE (1) DE59300496D1 (fr)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1043061A1 (fr) * 1999-03-27 2000-10-11 Guntram Krettek Dispositif de dispersion
DE19961088C2 (de) * 1999-12-17 2003-12-11 Mosel Vitelic Inc Vorrichtung zum Mischen von Chemikalien
ITBO20090604A1 (it) * 2009-09-23 2011-03-24 Samia S P A Impianto per la produzione di composizioni, quali stucchi, leganti e simili, particolarmente adatti all'impiego nell'industria conciaria e procedimento per la produzione di tali composizioni mediante un tale impianto
US20130008321A1 (en) * 2010-03-25 2013-01-10 G.S.G. S.R.L. Machine for the treatment of food mixtures with an improved performance
CN103657469A (zh) * 2013-12-26 2014-03-26 沈阳华盈环保材料有限公司 大开门三螺旋锥形混合机
CN105130144A (zh) * 2015-09-21 2015-12-09 河南金谷实业发展有限公司 药剂加注混合破碎一体装置
EP2985073A1 (fr) * 2014-08-11 2016-02-17 Remmers Baustofftechnik GmbH Procede et dispositif destines a la fabrication de couleurs et de vernis
EP2616171A4 (fr) * 2010-09-16 2018-01-17 Outotec (Finland) Oy Dispositif et procédé de dispersion de deux solutions l'une dans l'autre dans l'extraction de solvants
CN108554216A (zh) * 2018-06-01 2018-09-21 弘暖纤科技(北京)有限公司 搅拌装置
CN110917943A (zh) * 2019-11-13 2020-03-27 温州市天瑞制药机械有限公司 植物胶溶胶罐
CN110935358A (zh) * 2019-12-18 2020-03-31 泗县智固通机电设备有限公司 一种物料生产用混合罐
CN111013450A (zh) * 2020-01-17 2020-04-17 浙江厚达智能科技股份有限公司 旋转升降搅拌式中药煎桶
CN111266030A (zh) * 2020-03-19 2020-06-12 安庆市鑫富化工有限责任公司 一种用于制备3-氨基丙醇的快速混合装置
CN111569699A (zh) * 2020-05-25 2020-08-25 温学强 一种搅拌装置
WO2022243797A1 (fr) * 2021-05-20 2022-11-24 Precision Planting Llc Dispositif d'agitation de bouillie

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US6200937B1 (en) 1998-06-09 2001-03-13 Neutrogena Corporation Anti-residue shampoo and liquid toiletry production method
DE102007060455A1 (de) * 2007-12-12 2009-06-18 Deutsche Amphibolin-Werke Von Robert Murjahn Stiftung & Co. Kg Vorrichtung zum Durchmischen von Baumaterial

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US3246683A (en) * 1962-07-24 1966-04-19 Shell Oil Co Preparing slurry mixtures of pulverous solids and water
US3393898A (en) * 1967-03-29 1968-07-23 Agricultural Chemical Equipmen Fertilizer blender
FR2293968A1 (fr) * 1974-12-13 1976-07-09 Cem Comp Electro Mec Procede et dispositif pour realiser des emulsions gaz-liquide
DE2602858A1 (de) * 1975-02-05 1976-08-19 Melyepitesi Tervezo Vallalat Mischapparat fuer das beimischen von festem koernigem material zu fluessigkeiten
US4045004A (en) * 1976-10-01 1977-08-30 Berger Henry F Chemical mixing and pumping apparatus
GB2087753A (en) * 1980-02-20 1982-06-03 Mta Mueszaki Kemiai Kutato Int Mixing apparatus
FR2499869A1 (fr) * 1981-02-19 1982-08-20 Laffort Cie J Appareil permettant l'incorporation homogene et a des doses determinees de substances diverses dans un liquide sans alteration de ce liquide
DE3844174A1 (de) * 1988-12-29 1990-07-05 Fresenius Ag Anlage zur herstellung von konzentraten durch mischung von fluessigkeit mit loeslichem feststoff
EP0419280A1 (fr) * 1989-09-21 1991-03-27 Halliburton Company Appareil de mélange

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3246683A (en) * 1962-07-24 1966-04-19 Shell Oil Co Preparing slurry mixtures of pulverous solids and water
US3393898A (en) * 1967-03-29 1968-07-23 Agricultural Chemical Equipmen Fertilizer blender
FR2293968A1 (fr) * 1974-12-13 1976-07-09 Cem Comp Electro Mec Procede et dispositif pour realiser des emulsions gaz-liquide
DE2602858A1 (de) * 1975-02-05 1976-08-19 Melyepitesi Tervezo Vallalat Mischapparat fuer das beimischen von festem koernigem material zu fluessigkeiten
US4045004A (en) * 1976-10-01 1977-08-30 Berger Henry F Chemical mixing and pumping apparatus
GB2087753A (en) * 1980-02-20 1982-06-03 Mta Mueszaki Kemiai Kutato Int Mixing apparatus
FR2499869A1 (fr) * 1981-02-19 1982-08-20 Laffort Cie J Appareil permettant l'incorporation homogene et a des doses determinees de substances diverses dans un liquide sans alteration de ce liquide
DE3844174A1 (de) * 1988-12-29 1990-07-05 Fresenius Ag Anlage zur herstellung von konzentraten durch mischung von fluessigkeit mit loeslichem feststoff
EP0419280A1 (fr) * 1989-09-21 1991-03-27 Halliburton Company Appareil de mélange

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1043061A1 (fr) * 1999-03-27 2000-10-11 Guntram Krettek Dispositif de dispersion
DE19961088C2 (de) * 1999-12-17 2003-12-11 Mosel Vitelic Inc Vorrichtung zum Mischen von Chemikalien
ITBO20090604A1 (it) * 2009-09-23 2011-03-24 Samia S P A Impianto per la produzione di composizioni, quali stucchi, leganti e simili, particolarmente adatti all'impiego nell'industria conciaria e procedimento per la produzione di tali composizioni mediante un tale impianto
US9375689B2 (en) * 2010-03-25 2016-06-28 Bravo S.P.A. Machine for the treatment of food mixtures having scraping and mixing blades and a blender disposed parallel thereto
US20130008321A1 (en) * 2010-03-25 2013-01-10 G.S.G. S.R.L. Machine for the treatment of food mixtures with an improved performance
EP2616171A4 (fr) * 2010-09-16 2018-01-17 Outotec (Finland) Oy Dispositif et procédé de dispersion de deux solutions l'une dans l'autre dans l'extraction de solvants
CN103657469A (zh) * 2013-12-26 2014-03-26 沈阳华盈环保材料有限公司 大开门三螺旋锥形混合机
EP2985073A1 (fr) * 2014-08-11 2016-02-17 Remmers Baustofftechnik GmbH Procede et dispositif destines a la fabrication de couleurs et de vernis
CN105130144A (zh) * 2015-09-21 2015-12-09 河南金谷实业发展有限公司 药剂加注混合破碎一体装置
CN105130144B (zh) * 2015-09-21 2018-01-30 河南金谷实业发展有限公司 药剂加注混合破碎一体装置
CN108554216A (zh) * 2018-06-01 2018-09-21 弘暖纤科技(北京)有限公司 搅拌装置
CN108554216B (zh) * 2018-06-01 2024-03-19 北京弘暖纤科技有限公司 搅拌装置
CN110917943A (zh) * 2019-11-13 2020-03-27 温州市天瑞制药机械有限公司 植物胶溶胶罐
CN110917943B (zh) * 2019-11-13 2021-09-07 温州市天瑞制药机械有限公司 植物胶溶胶罐
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DE59300496D1 (de) 1995-09-28
EP0570335B1 (fr) 1995-08-23

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