EP0564383B1 - Device, especially used for microtechnical analysis - Google Patents

Device, especially used for microtechnical analysis Download PDF

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Publication number
EP0564383B1
EP0564383B1 EP93440030A EP93440030A EP0564383B1 EP 0564383 B1 EP0564383 B1 EP 0564383B1 EP 93440030 A EP93440030 A EP 93440030A EP 93440030 A EP93440030 A EP 93440030A EP 0564383 B1 EP0564383 B1 EP 0564383B1
Authority
EP
European Patent Office
Prior art keywords
tube
extended
ring
diameter
annular projections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP93440030A
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German (de)
French (fr)
Other versions
EP0564383A1 (en
Inventor
Marc Majurel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INSTITUT JACQUES BOY
Original Assignee
INSTITUT JACQUES BOY
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Filing date
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Application filed by INSTITUT JACQUES BOY filed Critical INSTITUT JACQUES BOY
Publication of EP0564383A1 publication Critical patent/EP0564383A1/en
Application granted granted Critical
Publication of EP0564383B1 publication Critical patent/EP0564383B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082Test tubes per se

Definitions

  • the subject of the present invention is a device including a micro-tube intended for microtechnology of analysis, in particular for the detection of erythrocytic agglutinates, said device having the advantageous characteristic of being able to adapt to standard test tubes, type hemolysis tubes, commonly used in medical analysis laboratories.
  • the devices used for this purpose range from standard hemolysis tubes to 96-well microplates, which have the first disadvantage of requiring the use of relatively large quantities of products, and the second, that of comprising a large number of microtubes and to be consequently of delicate handling, requiring in addition to resort to a specific instrument for its centrifugation.
  • the present invention makes it possible to remedy these drawbacks of known devices by proposing a device which can be adapted to standard test tubes of the hemolysis tube type, which gives it the advantage of great ease of handling linked to great flexibility of implementation, due to the fact that it can be used individually or in combination with one or more other identical tubes, depending on the type of analysis to be performed.
  • the present invention thus relates to a device incorporating a micro-tube which is essentially characterized in that it consists of a cylindrical tube extended at its upper end by a crown of larger diameter and at its lower end by a portion of frustoconical tube itself extended by a micro-tube inserted in a rectangular tab on the two faces of which it projects, and which extends to the upper edge of the portion of frustoconical tube at the level of which is disposed around the tube cylindrical a first annular projection, at a short distance above which is located a second annular projection, the diameter of said annular projections being substantially less than that of the crown.
  • the device of the invention can be produced by molding a semi-rigid plastic material of the polyethylene type.
  • the annular projections surrounding the cylindrical body may have a diameter very slightly greater than the internal diameter of a standard test tube, so as to center and keep the device in a vertical position in said test tube, the upper edge of which comes resting on the lower edge of the end crown.
  • the rectangular tongue can extend downwards by a certain length beyond the micro-tube, so as to allow on the one hand the easy gripping of the device during the manipulations, and on the other hand the affixing of a inscription allowing the identification of the tube.
  • the end ring has two flats allowing the writing of a reference number and facilitating the gripping of the device by its upper part.
  • a device 1 comprises a cylindrical tube 11 extended at its upper part by a crown 12 and at its lower part by a portion of frustoconical tube 13 it -Even extended by a micro-tube 10 whose lower end 19 is frustoconical and which is inserted into a rectangular tongue 14 used for affixing an inscription allowing the identification of the tube.
  • the cylindrical tube 11 is provided with two annular projections, one 15 arranged at its base and the other 16 at a short distance above, the diameters of these two annular projections being equal and substantially smaller than that of the end ring 12.
  • the end ring 12 is provided with two flats 17 and 18 intended for affixing reference numbers and also to allow better gripping of the device 1 by its upper part.
  • FIG. 2 we see in this figure the device 1 according to the invention placed in a standard test tube 2.
  • annular projections 15 and 16 allow the device 1, and therefore the micro-tube 10, to be kept in the vertical position, since it is in slight compression in the test tube 2, while the crown 12 comes to bear on the upper edge 21 of tube 2, from which it projects slightly.
  • the device according to the invention offers that, which is particularly appreciable, of not requiring suitable racks, replaced by standard test tubes which are commonly placed in racks which are also standard.
  • the device according to the invention can thus be placed in standard centrifuges, unlike certain existing devices, which require the use of centrifuges adapted to their dimensions.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The device comprises a cylindrical body (11) extended at its upper end by a crown ring (12) and at its lower end by a frustoconical segment (13), itself extended by a microtube (10) inserted into a rectangular tab (14) from the two faces of which it projects, and which is extended as far as the upper edge of the frustoconical segment (13), at which a first annular projection (15) is arranged around the cylindrical body (11), at a short distance above which a second annular projection (16) is arranged, the diameter of the said annular projections being substantially smaller than that of the crown ring (12) and being very slightly greater than the internal diameter of the standard test tubes in which the device (1) is intended to be placed, the crown ring (12) coming to bear with its lower edge on the upper edge (21) of the said standard test tubes. <IMAGE>

Description

La présente invention a pour objet un dispositif incluant un micro-tube destiné à des microtechniques d'analyse, notamment à la mise en évidence des agglutinats érythrocytaires, ledit dispositif présentant la particularité avantageuse de pouvoir s'adapter sur les tubes à essais standard, du type tubes à hémolyse, couramment utilisés dans les laboratoires d'analyses médicales.The subject of the present invention is a device including a micro-tube intended for microtechnology of analysis, in particular for the detection of erythrocytic agglutinates, said device having the advantageous characteristic of being able to adapt to standard test tubes, type hemolysis tubes, commonly used in medical analysis laboratories.

On connaît les contraintes attachées à certaines analyses, notamment immuno-hématologiques, qui doivent pouvoir être mises en oeuvres avec de très petites quantités de produits et conduire à des résultats aisément lisibles.We know the constraints attached to certain analyzes, in particular immuno-hematological, which must be able to be implemented with very small quantities of products and lead to easily readable results.

Les dispositifs utilisés à cet effet vont du tube à hémolyse standard aux microplaques à 96 puits, qui présentent, le premier l'inconvénient de nécessiter la mise en oeuvre de quantités de produits relativement importantes, et le second, celui de comporter un grand nombre de microtubes et d'être en conséquence de manipulation délicate, nécessitant en outre de recourir à un instrument spécifique pour sa centrifugation.The devices used for this purpose range from standard hemolysis tubes to 96-well microplates, which have the first disadvantage of requiring the use of relatively large quantities of products, and the second, that of comprising a large number of microtubes and to be consequently of delicate handling, requiring in addition to resort to a specific instrument for its centrifugation.

La présente invention permet de remédier à ces inconvénients des dispositifs connus en proposant un dispositif qui peut être adapté sur les tubes à essais standard du type tubes à hémolyse, ce qui lui confère l'avantage d'une grande facilité de manipulation liée à un grande souplesse de mise en oeuvre, due au fait qu'il peut être utilisé individuellement ou en association avec un ou plusieurs autres tubes identiques, selon le type d'analyse à effectuer.The present invention makes it possible to remedy these drawbacks of known devices by proposing a device which can be adapted to standard test tubes of the hemolysis tube type, which gives it the advantage of great ease of handling linked to great flexibility of implementation, due to the fact that it can be used individually or in combination with one or more other identical tubes, depending on the type of analysis to be performed.

La présente invention a ainsi pour objet un dispositif incorporant un micro-tube qui se caractérise essentiellement en ce qu'il est constitué d'un tube cylindrique prolongé à son extrémité supérieure par une couronne de plus grand diamètre et à son extrémité inférieure par une portion de tube tronconique elle-même prolongée par un micro-tube inséré dans une languette rectangulaire sur les deux faces de laquelle il fait saillie, et qui se prolonge jusqu'au bord supérieur de la portion de tube tronconique au niveau duquel est disposée autour du tube cylindrique une première saillie annulaire, à courte distance au-dessus de laquelle se trouve disposée une deuxième saille annulaire, le diamètre desdites saillies annulaires étant sensiblement inférieur à celui de la couronne.The present invention thus relates to a device incorporating a micro-tube which is essentially characterized in that it consists of a cylindrical tube extended at its upper end by a crown of larger diameter and at its lower end by a portion of frustoconical tube itself extended by a micro-tube inserted in a rectangular tab on the two faces of which it projects, and which extends to the upper edge of the portion of frustoconical tube at the level of which is disposed around the tube cylindrical a first annular projection, at a short distance above which is located a second annular projection, the diameter of said annular projections being substantially less than that of the crown.

Le dispositif de l'invention peut être réalisé par moulage d'une matière plastique semi-rigide du type polyéthylène.The device of the invention can be produced by molding a semi-rigid plastic material of the polyethylene type.

Les saillies annulaires entourant le corps cylindrique peuvent présenter un diamètre très légèrement supérieur au diamètre interne d'un tube à essais standard, de manière à assurer le centrage et le maintien du dispositif en position verticale dans ledit tube à essais, dont le bord supérieur vient en appui sur le bord inférieur de la couronne d'extrémité.The annular projections surrounding the cylindrical body may have a diameter very slightly greater than the internal diameter of a standard test tube, so as to center and keep the device in a vertical position in said test tube, the upper edge of which comes resting on the lower edge of the end crown.

La languette rectangulaire peut se prolonger vers le bas d'une certaine longueur au-delà du micro-tube, de manière à permettre d'une part la préhension aisée du dispositif pendant les manipulations, et d'autre part l'apposition d'une inscription permettant l'identification du tube.The rectangular tongue can extend downwards by a certain length beyond the micro-tube, so as to allow on the one hand the easy gripping of the device during the manipulations, and on the other hand the affixing of a inscription allowing the identification of the tube.

Par ailleurs, selon un mode de réalisation avantageux du dispositif selon l'invention, la couronne d'extrémité comporte deux méplats permettant l'inscription d'un numéro de référence et facilitant la préhension du dispositif par sa partie supérieure.Furthermore, according to an advantageous embodiment of the device according to the invention, the end ring has two flats allowing the writing of a reference number and facilitating the gripping of the device by its upper part.

Les caractéristiques et les avantages du dispositif selon l'invention seront mieux compris à la lecture de la description qui suit, faite en regard du dessin annexé qui en représente un mode de réalisation, étant bien entendu que cette description ne présente aucun caractère limitatif vis à vis de l'invention.The characteristics and advantages of the device according to the invention will be better understood on reading the description which follows, made with reference to the appended drawing which represents an embodiment thereof, it being understood that this description has no limiting character with regard to screw of the invention.

Dans le dessin annexé :

  • la figure 1 représente une vue en perspective d'un dispositif selon l'invention.
  • la figure 2 représente une vue en coupe de ce même dispositif mis en place dans un tube à essais.
In the attached drawing:
  • Figure 1 shows a perspective view of a device according to the invention.
  • 2 shows a sectional view of the same device installed in a test tube.

Si on se réfère d'abord à la figure 1, on voit qu'un dispositif 1 selon l'invention comprend un tube cylindrique 11 prolongé à sa partie supérieure par une couronne 12 et à sa partie inférieure par une portion de tube tronconique 13 elle-même prolongé par un micro-tube 10 dont l'extrémité inférieure 19 est tronconique et qui se trouve inséré dans une languette rectangulaire 14 servant à l'apposition d'une inscription permettant l'identification du tube.If we refer first to Figure 1, we see that a device 1 according to the invention comprises a cylindrical tube 11 extended at its upper part by a crown 12 and at its lower part by a portion of frustoconical tube 13 it -Even extended by a micro-tube 10 whose lower end 19 is frustoconical and which is inserted into a rectangular tongue 14 used for affixing an inscription allowing the identification of the tube.

Le tube cylindrique 11 est muni de deux saillies annulaires, l'une 15 disposée à sa base et l'autre 16 à une courte distance au-dessus, les diamètres de ces deux saillies annulaires étant égaux et sensiblement inférieurs à celui de la couronne d'extrémité 12.The cylindrical tube 11 is provided with two annular projections, one 15 arranged at its base and the other 16 at a short distance above, the diameters of these two annular projections being equal and substantially smaller than that of the end ring 12.

La couronne d'extrémité 12 est munie de deux méplats 17 et 18 destinés à l'apposition de numéros de référence et également à permettre une meilleure préhension du dispositif 1 par sa partie supérieure.The end ring 12 is provided with two flats 17 and 18 intended for affixing reference numbers and also to allow better gripping of the device 1 by its upper part.

Si on se réfère maintenant à la figure 2, on voit sur cette figure le dispositif 1 selon l'invention mis en place dans un tube à essais standard 2.If we now refer to FIG. 2, we see in this figure the device 1 according to the invention placed in a standard test tube 2.

On constate que les saillies annulaires 15 et 16 permettent le maintien en position verticale du dispositif 1, et donc du micro-tube 10, car se trouvant en légère compression dans le tube à essais 2, tandis que la couronne 12 vient en appui sur le bord supérieur 21 du tube 2, d'où elle dépasse légèrement.It can be seen that the annular projections 15 and 16 allow the device 1, and therefore the micro-tube 10, to be kept in the vertical position, since it is in slight compression in the test tube 2, while the crown 12 comes to bear on the upper edge 21 of tube 2, from which it projects slightly.

Outre les avantages déjà exposés, le dispositif selon l'invention offre celui, particulièrement appréciable, de ne pas nécessiter de portoirs adaptés, remplacés par les tubes à essais standard qui sont couramment placés dans des portoirs également standard.In addition to the advantages already explained, the device according to the invention offers that, which is particularly appreciable, of not requiring suitable racks, replaced by standard test tubes which are commonly placed in racks which are also standard.

Le dispositif selon l'invention peut ainsi être placé dans des centrifugeuses standard, à la différence de certains dispositifs existants, qui nécessitent de recourir à des centrifugeuses adaptées à leurs dimensions.The device according to the invention can thus be placed in standard centrifuges, unlike certain existing devices, which require the use of centrifuges adapted to their dimensions.

Claims (3)

  1. Device (1) which is destined in particular for implementation of micro-analysis techniques, comprising a cylindrical tube (11) which is extended at its upper end by a ring (12) with a larger diameter, and at its lower end by a portion of frusto-conical tube (13) which itself is extended by a microtube (10) inserted in a rectangular tongue (14), on both surfaces of which it projects, and which tongue extends to the upper edge of the portion of frusto-conical tube (13), at the level of which there is disposed around the cylindrical body (11) a first annular projection (15), a short distance above which there is disposed a second annular projection (16), the diameter of these annular projections (15, 16) being substantially smaller than that of the ring (12).
  2. Device according to claim 1, characterised in that the ring (12) is provided with two flattened portions (17, 18), which permit firstly inscription of a reference number, and secondly improved grasping of the device by its upper part.
  3. System destined in particular for implementation of micro-analysis techniques, characterised in that it comprises a device (1) according to one of claims 1 and 2, and a standard test tube (2), and in that the diameter of the annular projections (15, 16) is greater than the inner diameter of the test tube (2), to the extent that these annular projections (15, 16) are in a condition of slight compression when the device (1) is inserted in the test tube (2) with the ring (12) supported by its lower edge on the upper edge of the tube (2).
EP93440030A 1992-03-23 1993-03-23 Device, especially used for microtechnical analysis Expired - Lifetime EP0564383B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9203624 1992-03-23
FR929203624A FR2688888B1 (en) 1992-03-23 1992-03-23 DEVICE IN PARTICULAR FOR THE IMPLEMENTATION OF MICROTECHNICS OF ANALYSIS.

Publications (2)

Publication Number Publication Date
EP0564383A1 EP0564383A1 (en) 1993-10-06
EP0564383B1 true EP0564383B1 (en) 1996-07-24

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Application Number Title Priority Date Filing Date
EP93440030A Expired - Lifetime EP0564383B1 (en) 1992-03-23 1993-03-23 Device, especially used for microtechnical analysis

Country Status (5)

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EP (1) EP0564383B1 (en)
AT (1) ATE140641T1 (en)
DE (1) DE69303750T2 (en)
ES (1) ES2092265T3 (en)
FR (1) FR2688888B1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5915583A (en) * 1997-05-21 1999-06-29 Abbott Laboraties Container
US5924594A (en) * 1997-09-12 1999-07-20 Becton Dickinson And Company Collection container assembly

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES275137Y (en) * 1981-07-20 1984-10-01 American Hospital Supply Corporation A CONTAINER TO CONTAIN A SMALL AMOUNT OF LIQUID.
EP0245994A3 (en) * 1986-04-28 1988-07-06 Ici Australia Limited Method and apparatus for reaction
IE904353A1 (en) * 1990-03-29 1991-10-09 Becton Dickinson Co Compartmental body fluid collection tube

Also Published As

Publication number Publication date
FR2688888B1 (en) 1994-07-01
ES2092265T3 (en) 1996-11-16
DE69303750T2 (en) 1997-03-06
DE69303750D1 (en) 1996-08-29
ATE140641T1 (en) 1996-08-15
EP0564383A1 (en) 1993-10-06
FR2688888A1 (en) 1993-09-24

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