EP0557273A4 - - Google Patents

Info

Publication number
EP0557273A4
EP0557273A4 EP19900917617 EP90917617A EP0557273A4 EP 0557273 A4 EP0557273 A4 EP 0557273A4 EP 19900917617 EP19900917617 EP 19900917617 EP 90917617 A EP90917617 A EP 90917617A EP 0557273 A4 EP0557273 A4 EP 0557273A4
Authority
EP
European Patent Office
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900917617
Other versions
EP0557273A1 (en
Inventor
Takashi Akamizu
Shoichiro Ikuyama
Motoyasu Saji
Shinji Kosugi
Toshiaki Ban
Leonard D. Kohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of EP0557273A1 publication Critical patent/EP0557273A1/en
Publication of EP0557273A4 publication Critical patent/EP0557273A4/xx
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP90917617A 1990-11-15 1990-11-15 Rat thyrotropin receptor gene and uses thereof Withdrawn EP0557273A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1990/006533 WO1992008726A1 (en) 1990-11-15 1990-11-15 Rat thyrotropin receptor gene and uses thereof

Publications (2)

Publication Number Publication Date
EP0557273A1 EP0557273A1 (en) 1993-09-01
EP0557273A4 true EP0557273A4 (en) 1994-01-12

Family

ID=22221148

Family Applications (1)

Application Number Title Priority Date Filing Date
EP90917617A Withdrawn EP0557273A1 (en) 1990-11-15 1990-11-15 Rat thyrotropin receptor gene and uses thereof

Country Status (3)

Country Link
EP (1) EP0557273A1 (en)
CA (1) CA2095013A1 (en)
WO (1) WO1992008726A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0506890A4 (en) * 1989-12-20 1993-06-30 Nichols Institute Diagnostics Recombinant thyrotropin receptor
JP2000512280A (en) * 1996-06-05 2000-09-19 ラポポート，バジル Human thyroid stimulating hormone receptor composition and use thereof
GB2376016A (en) * 2001-05-30 2002-12-04 Nadir R Farid Thyrotropin receptor (TSHR) domain cleavage catalysed by the metalloprotease ADAM 10

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472508A (en) * 1982-12-30 1984-09-18 The Beth Israel Hospital Association Test for detecting and measuring the graves' disease-specific immunoglobulins
US4609622A (en) * 1983-05-31 1986-09-02 Interthyr Research Foundation Inc. Clinical determination and/or quantification of thyrotropin and a variety of thyroid stimulatory or inhibitory factors performed in vitro with an improved thyroid cell line, FRTL-5
US4973578A (en) * 1988-03-17 1990-11-27 Mayo Foundation For Medical Education And Research Synthetic peptides derived from the alpha-subunit of human lycoprotein hormones

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA. vol. 87, August 1990, WASHINGTON US pages 5677 - 5681 Akamizu T;Ikuyama S;Saji M;Kosugi S;Kozak C;McBride OW;Kohn LD 'Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.' *
See also references of WO9208726A1 *

Also Published As

Publication number Publication date
CA2095013A1 (en) 1992-05-16
EP0557273A1 (en) 1993-09-01
WO1992008726A1 (en) 1992-05-29

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19930504

AK Designated contracting states

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RHK1 Main classification (correction)

Ipc: C12N 15/12

A4 Supplementary search report drawn up and despatched

Effective date: 19931123

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Withdrawal date: 19940301