EP0551084A3 - Human antithrombin-iii preparation - Google Patents

Human antithrombin-iii preparation Download PDF

Info

Publication number
EP0551084A3
EP0551084A3 EP9393100056A EP93100056A EP0551084A3 EP 0551084 A3 EP0551084 A3 EP 0551084A3 EP 9393100056 A EP9393100056 A EP 9393100056A EP 93100056 A EP93100056 A EP 93100056A EP 0551084 A3 EP0551084 A3 EP 0551084A3
Authority
EP
European Patent Office
Prior art keywords
iii preparation
human antithrombin
antithrombin
human
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP9393100056A
Other languages
English (en)
Other versions
EP0551084A2 (en
Inventor
Yahiro Uemura
Prabir Bhattcharya
Swaraj Kaur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha Therapeutic Corp
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Publication of EP0551084A2 publication Critical patent/EP0551084A2/en
Publication of EP0551084A3 publication Critical patent/EP0551084A3/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8128—Antithrombin III
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/106664—Blood serum or blood plasma standard or control

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP9393100056A 1992-01-10 1993-01-05 Human antithrombin-iii preparation Withdrawn EP0551084A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/818,831 US5319072A (en) 1992-01-10 1992-01-10 Human antithrombin-III preparation
US818831 1992-01-10

Publications (2)

Publication Number Publication Date
EP0551084A2 EP0551084A2 (en) 1993-07-14
EP0551084A3 true EP0551084A3 (en) 1994-09-28

Family

ID=25226534

Family Applications (1)

Application Number Title Priority Date Filing Date
EP9393100056A Withdrawn EP0551084A3 (en) 1992-01-10 1993-01-05 Human antithrombin-iii preparation

Country Status (4)

Country Link
US (1) US5319072A (ja)
EP (1) EP0551084A3 (ja)
JP (1) JP3471379B2 (ja)
CA (1) CA2085953C (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3494667B2 (ja) * 1992-10-02 2004-02-09 アベンティス ファーマ株式会社 アンチトロンビンｉｉｉ製剤
KR100330540B1 (ko) * 1993-04-05 2002-09-04 웰파이드 코포레이션 안티트롬빈-iii액상제제및그안정화방법
US5610285A (en) * 1994-08-24 1997-03-11 Bayer Corporation Purification of α-1 proteinase inhibitor using novel chromatographic separation conditions
US5767108A (en) * 1995-08-22 1998-06-16 Medtronic, Inc. Method for making improved heparinized biomaterials
US6562781B1 (en) 1995-11-30 2003-05-13 Hamilton Civic Hospitals Research Development Inc. Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US6491965B1 (en) * 1995-11-30 2002-12-10 Hamilton Civic Hospitals Research Development, Inc. Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US7045585B2 (en) * 1995-11-30 2006-05-16 Hamilton Civic Hospital Research Development Inc. Methods of coating a device using anti-thrombin heparin
AT405739B (de) * 1997-09-19 1999-11-25 Immuno Ag Verfahren zur reinigung von antithrombin iii
US6245741B1 (en) 1998-05-19 2001-06-12 Washington University Protein Z-dependent protease inhibitor
JP2002526418A (ja) 1998-10-08 2002-08-20 チルドレンズ ホスピタル 血管形成を阻害するための組成物と方法
US6462180B1 (en) 1999-11-24 2002-10-08 Bayer Corporation Method of preparing α-1 proteinase inhibitor
EP2522354B1 (en) * 2011-05-12 2017-08-23 CSL Behring GmbH Methods to reduce adverse events caused by pharmaceutical preparations comprising plasma derived proteins

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6048930A (ja) * 1983-08-24 1985-03-16 Nippon Sekijiyuujishiya アンチトロンビン３の精製法
EP0224811A2 (en) * 1985-12-02 1987-06-10 Miles Inc. Improved method of preparing alpha-1-proteinase inhibitor
EP0339919A2 (en) * 1988-04-28 1989-11-02 The Green Cross Corporation Method for purifying antithrombin-III and antithrombin-III preparation containing said antithrombin-III
EP0408029A1 (en) * 1989-07-12 1991-01-16 The Green Cross Corporation Method of fractionating plasma protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632981A (en) * 1982-07-30 1986-12-30 Genentech, Inc. Human antithrombin III
US5066788A (en) * 1984-09-21 1991-11-19 Boehringer Ingelheim International Gmbh Blood coagulation inhibiting proteins, processes for preparing them and their uses

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6048930A (ja) * 1983-08-24 1985-03-16 Nippon Sekijiyuujishiya アンチトロンビン３の精製法
EP0224811A2 (en) * 1985-12-02 1987-06-10 Miles Inc. Improved method of preparing alpha-1-proteinase inhibitor
EP0339919A2 (en) * 1988-04-28 1989-11-02 The Green Cross Corporation Method for purifying antithrombin-III and antithrombin-III preparation containing said antithrombin-III
EP0408029A1 (en) * 1989-07-12 1991-01-16 The Green Cross Corporation Method of fractionating plasma protein

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CESK. FARM., vol. 31, no. 1, pages 27 - 29 *
CHEMICAL ABSTRACTS, vol. 103, no. 6, 12 August 1985, Columbus, Ohio, US; abstract no. 42631g, "Purification of antithrobin III from blood plasma." page 354; *
CHEMICAL ABSTRACTS, vol. 96, no. 19, 10 May 1982, Columbus, Ohio, US; abstract no. 158030b, RYBAK M. ET AL.: "Separation and purification of antithrombin III, thrombin and carboxypeptidase N by affinity sorption on hydroxymethacrylate with immobilized heparin" page 331; *

Also Published As

Publication number Publication date
US5319072A (en) 1994-06-07
CA2085953A1 (en) 1993-07-11
JPH06128296A (ja) 1994-05-10
EP0551084A2 (en) 1993-07-14
CA2085953C (en) 2002-02-19
JP3471379B2 (ja) 2003-12-02

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