EP0459818A1 - Emballage pour suppositoires, ouvrable par pelage - Google Patents

Emballage pour suppositoires, ouvrable par pelage Download PDF

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Publication number
EP0459818A1
EP0459818A1 EP91304933A EP91304933A EP0459818A1 EP 0459818 A1 EP0459818 A1 EP 0459818A1 EP 91304933 A EP91304933 A EP 91304933A EP 91304933 A EP91304933 A EP 91304933A EP 0459818 A1 EP0459818 A1 EP 0459818A1
Authority
EP
European Patent Office
Prior art keywords
suppository
container
bulges
sheets
peel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP91304933A
Other languages
German (de)
English (en)
Inventor
Niro Sotta
Shigeru Takamuku
Shoji Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of EP0459818A1 publication Critical patent/EP0459818A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52Details
    • B65D75/58Opening or contents-removing devices added or incorporated during package manufacture
    • B65D75/5855Peelable seals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/08Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of suppositories or sticks
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/321Both sheets being recessed
    • B65D75/323Both sheets being recessed and forming several compartments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D2575/3209Details
    • B65D2575/3218Details with special means for gaining access to the contents
    • B65D2575/3245Details with special means for gaining access to the contents by peeling off the non-rigid sheet

Definitions

  • the present invention relates to an improved peel-openable container for suppository.
  • a conventional typical container (1) for suppository is generally produced by overlapping two sheets (10) and (11) each made of a synthetic resin, etc. and having a plurality of bulges (12) for containing a suppository and suppository inlets (13) connecting with the bulges, so that the bulges of one sheet face the bulges of other sheet at the respective peripheries and then heat-sealing the overlapped portion of the two sheets excluding the bulges (12), in a form of a number of lines with appropriate line-to-line intervals, to form a sealed portion (15) with one end of each sheet left unsealed so as to serve as a holding rib (14) for easy opening.
  • the thus produced suppository container (1) can be made into a packed suppository product (2) as shown in Fig. 4 by injecting a molten suppository composition into the bulges (12) through the inlets (13), cooling and solidifying the composition, heat-sealing the inlets (13), and forming stitches (16) for separation of packed suppository product into individual suppository units.
  • the sealed portion (15) is formed by effecting heat-sealing in a form of lines with appropriate line-to-line intervals and not by heat-sealing the whole area of the overlapped sheet portion.
  • the reason for effecting heat-sealing in this way is to ensure easy peeling when a packed suppository product (2) produced from the container (1) as shown in Fig. 4 is separated into individual suppository units by means of the stitches (16) and the sheets (10) and (11) are peeled from each other by means of the holding ribs (14) to take out a suppository.
  • the sealed portion (15) is formed by effecting heat-sealing in a form of a plurality of lines as shown in Fig. 3 and then a molten suppository composition is injected into the bulges (12), however, the suppository (3) in each bulge has fine notches (31) at the both sides as shown in Fig. 5 because the molten composition injected into each bulge (12) penetrates into the unsealed gaps of the overlapped portion of the two sheets at the periphery of each bulge.
  • notches (31) not only give poor appearance to the suppository but also give, in some cases, a stimulus to the diseased part when inserted into the anus. Even if the notches are not large enough to actually give a stimulus to the diseased part, it is highly probable that the patient, when seeing the notches, have a feeling of uneasiness to such stimulus.
  • the main object of the present invention is to provide a suppository container free from the above-mentioned drawbacks of the prior art.
  • a peel-openable container for suppository produced by overlapping two sheets each having a plurality of bulges for containing a suppository, with each other so that the bulges of one sheet face the bulges of other sheet at the respective peripheries and then sealing the overlapped portion of the two sheets excluding the bulges, in a form of a number of lines with appropriate line-to-line intervals, in which container smooth uniformly sealed areas of such small width as to give substantially no hindrance to peel-opening of the container are formed at least at the portions along the two-side contours of each bulge.
  • the suppository container of the present invention smooth uniformly sealed areas of such small width as to give substantially no hindrance to peel-opening of the container are formed at least at the portions along the two-side contours of each bulge; consequently, the molten suppository composition injected into the bulge does not penetrate into the unsealed gaps of the overlapped portion of the two sheets at the periphery of the bulge, unlike the case of the conventional suppository container.
  • the packed suppository product has no notches at the both sides, has a smooth surface, gives no stimulus to the diseased part when inserted into the anus, and gives no feeling of uneasiness to the patient.
  • Fig. 1 is a front view showing an example of the suppository container of the present invention
  • Fig. 2 is a front view showing an example of the packed suppository product of the present invention
  • Fig. 3 is a perspective view of the conventional suppository container
  • Fig. 4 is a front view of a conventional packed suppository product
  • Fig. 5 is a half enlarged view of a suppository taken out of the packed suppository product of Fig. 4.
  • a peel-openable container (1) for suppository can be produced by overlapping two sheets (10) and (11) each having a plurality of bulges (12) for containing a suppository and suppository inlets (13) extending from the end of each bulge to the end of each sheet, so that the bulges of one sheet face the bulges of other sheet at the respective peripheries and then sealing the overlapped portion (15) of the two sheets excluding the bulges (12), in a form of a number of lines with appropriate line-to-line intervals.
  • the sealing lines need not necessarily be continuous lines and may be dotted lines. The width of each sealing line can be determined empirically, depending upon the material of sheet, the method of sealing (or jointing), etc.
  • the suppository container of the present invention is characterized in that smooth uniformly sealed areas (17) of such small width as to give substantially no hindrance to peel-opening of the container (1) are formed at least at the portions along the two-side contours of each bulge (12).
  • the width of the uniformly sealed areas (17) can be changed depending upon the material of sheet, the method of sealing (or jointing), etc., but appropriately is generally 0.1 to 3 mm, preferably 0.5 to 1.5 mm.
  • ribs (14) for easy opening of the container (these ribs are not subjected to linear sealing), at one end of the overlapped and sealed sheets, generally at the end opposite to the end having suppository inlets (13).
  • These ribs (14) can have protuberances (19) for easy pinching of the ribs for fingers.
  • the material of the sheets used for producing a suppository container of the present invention has no particular restriction, but is preferably natural, semi-synthetic or synthetic resins, particularly heat-sealable thermoplastic resins such as polypropylene, polyvinyl chloride and a laminate sheet of polyvinyl chloride and polyethylene.
  • a suppository container of the present invention from sheets made of such a resin can be effected by a per se known process.
  • the suppository container of the present invention can be produced, for example, by overlapping two sheets, setting the overlapped sheets in a mold formed so as to provide a molded article as shown in Fig. 1, and subjecting the sheets to vacuum forming or pressure forming with heating to form bulges and simultaneously heat-seal the overlapped portion of the sheets.
  • the thus produced suppository container (1) of the present invention as shown in Fig. 1 can be made into a packed suppository product (2) as shown in Fig. 2, by injecting a predetermined amount of a molten suppository composition into each bulge (12) through the suppository inlet (13), cooling and solidifying the composition, heat-sealing the inlet (13) to form a sealed portion (18), and forming stitches (16) for easy separation of packed suppository product into individual suppository units.
  • the packed suppository product is separated into individual suppository units by means of the stitches (16); each suppository unit is subjected to peel-opening by means of the holding ribs (14); thereby, a molded suppository can be taken out of each bulge (12).
  • the molded suppository has substantially no flash as shown in Fig. 5, has a smooth surface, gives substantially no stimulus to the diseased part when inserted to the anus, and gives no feeling of uneasiness to the patient.
  • the "suppository container" of the present invention includes not only a molding as shown in Fig. 1 but also other molding produced according to a process other than the above process.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Composite Materials (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Packages (AREA)
EP91304933A 1990-05-31 1991-05-31 Emballage pour suppositoires, ouvrable par pelage Withdrawn EP0459818A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2142468A JPH0640892B2 (ja) 1990-05-31 1990-05-31 坐剤成型包装体及び坐剤用コンテナ
JP142468/90 1990-05-31

Publications (1)

Publication Number Publication Date
EP0459818A1 true EP0459818A1 (fr) 1991-12-04

Family

ID=15316019

Family Applications (1)

Application Number Title Priority Date Filing Date
EP91304933A Withdrawn EP0459818A1 (fr) 1990-05-31 1991-05-31 Emballage pour suppositoires, ouvrable par pelage

Country Status (3)

Country Link
EP (1) EP0459818A1 (fr)
JP (1) JPH0640892B2 (fr)
KR (1) KR910019590A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999048768A1 (fr) * 1998-03-25 1999-09-30 Elopak Systems A/G Recipient a ouverture pelable
WO2000056263A1 (fr) * 1999-03-23 2000-09-28 Taisho Pharmaceutical Co., Ltd. Emballage pour suppositoire et procede de production associe
WO2003009666A1 (fr) * 2001-07-26 2003-02-06 Barroso Perez Concepcion Methode d'administration de medicaments et dispositifs destines a mettre en oeuvre ladite methode
WO2015074644A1 (fr) * 2013-11-21 2015-05-28 Dr.-Ing. Jens Sebastian, Dipl.-Ing. Florian Wiest Gbr Emballage, article moulé avec emballage, ainsi que dispositif et procédé de fabrication correspendants

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017187766A1 (fr) * 2016-04-26 2017-11-02 株式会社彫刻プラスト Film stratifié pour emballage sous enveloppe pelliplaquée, corps d'emballage et procédé de fabrication de corps d'emballage

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1067307A (fr) * 1954-06-15
US3039246A (en) * 1959-08-06 1962-06-19 Ivers Lee Co Suppository package and method of making it
FR1417341A (fr) * 1964-10-02 1965-11-12 Procédé d'assemblage de deux surfaces juxtaposées, en vue d'en faciliter la séparation
FR1530471A (fr) * 1967-04-06 1968-06-28 Charles Nicolle Ets Emballage en matière plastique, notamment pour le moulage et le conditionnement de suppositoires

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6010761B2 (ja) * 1981-11-11 1985-03-20 株式会社西村渡辺抽出研究所 晶析装置
JPS6010761U (ja) * 1983-06-30 1985-01-24 株式会社 大塚製薬工場 坐薬容器

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1067307A (fr) * 1954-06-15
US3039246A (en) * 1959-08-06 1962-06-19 Ivers Lee Co Suppository package and method of making it
FR1417341A (fr) * 1964-10-02 1965-11-12 Procédé d'assemblage de deux surfaces juxtaposées, en vue d'en faciliter la séparation
FR1530471A (fr) * 1967-04-06 1968-06-28 Charles Nicolle Ets Emballage en matière plastique, notamment pour le moulage et le conditionnement de suppositoires

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999048768A1 (fr) * 1998-03-25 1999-09-30 Elopak Systems A/G Recipient a ouverture pelable
EP1306316A1 (fr) * 1998-03-25 2003-05-02 Elopak Systems Ag Récipient à ouverture pelable
WO2000056263A1 (fr) * 1999-03-23 2000-09-28 Taisho Pharmaceutical Co., Ltd. Emballage pour suppositoire et procede de production associe
WO2003009666A1 (fr) * 2001-07-26 2003-02-06 Barroso Perez Concepcion Methode d'administration de medicaments et dispositifs destines a mettre en oeuvre ladite methode
WO2015074644A1 (fr) * 2013-11-21 2015-05-28 Dr.-Ing. Jens Sebastian, Dipl.-Ing. Florian Wiest Gbr Emballage, article moulé avec emballage, ainsi que dispositif et procédé de fabrication correspendants
US11084614B2 (en) 2013-11-21 2021-08-10 Sebastian, Jens, Dr. Packaging, a shaped object having packaging, and a device and method for producing same

Also Published As

Publication number Publication date
JPH0435665A (ja) 1992-02-06
KR910019590A (ko) 1991-12-19
JPH0640892B2 (ja) 1994-06-01

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