EP0436625A4 - Mixed feed recombinant yeast fermentation - Google Patents

Mixed feed recombinant yeast fermentation

Info

Publication number
EP0436625A4
EP0436625A4 EP19890911170 EP89911170A EP0436625A4 EP 0436625 A4 EP0436625 A4 EP 0436625A4 EP 19890911170 EP19890911170 EP 19890911170 EP 89911170 A EP89911170 A EP 89911170A EP 0436625 A4 EP0436625 A4 EP 0436625A4
Authority
EP
European Patent Office
Prior art keywords
mixed feed
recombinant yeast
yeast fermentation
feed recombinant
fermentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19890911170
Other languages
English (en)
Other versions
EP0436625A1 (en
Inventor
Russell Arthur Brierley
Robert Steven Siegel
Christopher Michael Bussineau
William Scot Craig
Gregory Clyde Holtz
Geneva Ruth Davis
Richard Gordon Buckholz
Gregory Patrick Thill
Lillian Margaret Wondrack
Mary Ellen Digan
Michael Miller Harpold
Stephen Vernon Lair
Steven Bradley Ellis
Mark Edward Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIBIA Neurosciences Inc
Original Assignee
Salk Institute Biotechnology Industrial Associates Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/265,446 external-priority patent/US4875200A/en
Priority claimed from US07/323,964 external-priority patent/US5102789A/en
Application filed by Salk Institute Biotechnology Industrial Associates Inc filed Critical Salk Institute Biotechnology Industrial Associates Inc
Publication of EP0436625A1 publication Critical patent/EP0436625A1/en
Publication of EP0436625A4 publication Critical patent/EP0436625A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462—Lysozyme (3.2.1.17)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP19890911170 1988-09-26 1989-09-25 Mixed feed recombinant yeast fermentation Withdrawn EP0436625A4 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US24944688A 1988-09-26 1988-09-26
US249446 1988-09-26
US07/265,446 US4875200A (en) 1988-11-01 1988-11-01 Illuminating bezel
US265446 1988-11-01
US31151789A 1989-02-13 1989-02-13
US311517 1989-02-13
US07/323,964 US5102789A (en) 1989-03-15 1989-03-15 Production of epideramal growth factor in pichia pastoris yeast cells
US323964 1994-10-17

Publications (2)

Publication Number Publication Date
EP0436625A1 EP0436625A1 (en) 1991-07-17
EP0436625A4 true EP0436625A4 (en) 1991-08-21

Family

ID=27500320

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19890911170 Withdrawn EP0436625A4 (en) 1988-09-26 1989-09-25 Mixed feed recombinant yeast fermentation

Country Status (6)

Country Link
EP (1) EP0436625A4 (da)
JP (1) JPH04501662A (da)
AU (1) AU4332589A (da)
DK (1) DK55191A (da)
IL (1) IL91765A0 (da)
WO (1) WO1990003431A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5434135A (en) * 1990-08-02 1995-07-18 Indu Parikh Growth factor compositions, preparation and use
AU660421B2 (en) * 1990-08-02 1995-06-29 Indu Parikh Growth factor compositions, preparation and use
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
JPH06500470A (ja) * 1990-09-04 1994-01-20 メルク　エンド　カンパニー　インコーポレーテッド メチロトローフ酵母細胞におけるインスリン様成長因子の産生
WO1992013951A1 (en) * 1991-02-04 1992-08-20 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of human serum albumin in methylotrophic yeast cells
ATE220105T1 (de) * 1991-04-01 2002-07-15 Merck & Co Inc Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung
GB9402832D0 (en) * 1994-02-15 1994-04-06 Smith Kline Beecham Biolog S A Novel process
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6124439A (en) * 1994-08-17 2000-09-26 The Rockefeller University OB polypeptide antibodies and method of making
US6350730B1 (en) 1994-08-17 2002-02-26 The Rockefeller University OB polypeptides and modified forms as modulators of body weight
US6048837A (en) * 1994-08-17 2000-04-11 The Rockefeller University OB polypeptides as modulators of body weight
US6471956B1 (en) 1994-08-17 2002-10-29 The Rockefeller University Ob polypeptides, modified forms and compositions thereto
US6309853B1 (en) 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
US6124448A (en) * 1994-08-17 2000-09-26 The Rockfeller University Nucleic acid primers and probes for the mammalian OB gene
ES2264181T3 (es) * 1997-10-01 2006-12-16 Dsm Ip Assets B.V. Procedimiento para la produccion de proteinas.
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
US6773911B1 (en) 1998-11-23 2004-08-10 Amgen Canada Inc. Apoptosis-inducing factor
AU3910000A (en) * 1999-03-22 2000-10-09 Zymogenetics Inc. Improved methods for producing proteins in transformed (pichia)
US6258559B1 (en) 1999-03-22 2001-07-10 Zymogenetics, Inc. Method for producing proteins in transformed Pichia
AU2002356880A1 (en) 2001-10-31 2003-05-12 Phytex, Llc Phytase-containing animal food and method
US6793911B2 (en) * 2002-02-05 2004-09-21 Abb Lummus Global Inc. Nanocrystalline inorganic based zeolite and method for making same
CA2498017C (en) 2002-09-13 2016-06-14 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
US7919297B2 (en) 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
WO2008017066A2 (en) 2006-08-03 2008-02-07 Cornell Research Foundation, Inc. Phytases with improved thermal stability
DK2106447T3 (da) * 2007-01-26 2013-06-24 Novozymes As Fremgangsmåde til methanoluafhængig induktion fra methanolinducerbare promotorer i Pichia
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
CN106191181B (zh) 2016-07-22 2019-12-13 江苏江山聚源生物技术有限公司 一种毕赤酵母表达重组蛋白的发酵工艺
WO2018158335A1 (en) * 2017-02-28 2018-09-07 Vib Vzw Means and methods for oral protein delivery

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0226846A1 (en) * 1985-11-26 1987-07-01 Phillips Petroleum Company Yeast production of hepatitis B Surface antigen
WO1989004320A1 (en) * 1987-11-02 1989-05-18 The Salk Institute Biotechnology/Industrial Associ PRODUCTION OF ANIMAL LYSOZYME c VIA SECRETION FROM PICHIA PASTORIS AND COMPOSITION THEREFOR

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE155527T1 (de) * 1983-10-03 1997-08-15 Chiron Corp Superoxiddismutase und deren expression in mikroorganismen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0226846A1 (en) * 1985-11-26 1987-07-01 Phillips Petroleum Company Yeast production of hepatitis B Surface antigen
WO1989004320A1 (en) * 1987-11-02 1989-05-18 The Salk Institute Biotechnology/Industrial Associ PRODUCTION OF ANIMAL LYSOZYME c VIA SECRETION FROM PICHIA PASTORIS AND COMPOSITION THEREFOR

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS DATABASE, Abstract no.26044335, Accession no 84044335; R.J.White et al : "Ruminant stomach lysozymes functional perculiarities amino-acid sequence and genomic cloning " & Federation Proceedings ,1983, vol 42, no 7, page 1253 *
PASCAL DATABASE Abstract no 88 0425984, Accession no 88425086. J.M.Cregg et al : " Development of the methylotropic yeast, Pichia Pastoris, as a host system for the production of foreign proteins " & Dev. in industrial microbiology, 1988 vol 29,supp 3,pages 33-41 *
See also references of WO9003431A1 *

Also Published As

Publication number Publication date
EP0436625A1 (en) 1991-07-17
WO1990003431A1 (en) 1990-04-05
JPH04501662A (ja) 1992-03-26
DK55191A (da) 1991-05-24
DK55191D0 (da) 1991-03-26
AU4332589A (en) 1990-04-18
IL91765A0 (en) 1990-06-10

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