EP0316200A2 - Medizinisches Ultraschallabbildungssystem - Google Patents
Medizinisches Ultraschallabbildungssystem Download PDFInfo
- Publication number
- EP0316200A2 EP0316200A2 EP88310686A EP88310686A EP0316200A2 EP 0316200 A2 EP0316200 A2 EP 0316200A2 EP 88310686 A EP88310686 A EP 88310686A EP 88310686 A EP88310686 A EP 88310686A EP 0316200 A2 EP0316200 A2 EP 0316200A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- velocity
- rejection
- samples
- signal
- clutter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002604 ultrasonography Methods 0.000 title claims description 16
- 238000003384 imaging method Methods 0.000 title description 4
- 230000017531 blood circulation Effects 0.000 claims abstract description 23
- 230000001419 dependent effect Effects 0.000 claims abstract description 15
- 238000002592 echocardiography Methods 0.000 claims abstract description 9
- 238000001914 filtration Methods 0.000 claims abstract description 5
- 238000012545 processing Methods 0.000 claims description 13
- 230000004044 response Effects 0.000 claims description 9
- 230000001629 suppression Effects 0.000 claims 1
- 238000012285 ultrasound imaging Methods 0.000 abstract description 5
- 238000012546 transfer Methods 0.000 abstract description 2
- 230000006870 function Effects 0.000 description 22
- 238000005070 sampling Methods 0.000 description 8
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 238000004364 calculation method Methods 0.000 description 5
- 230000000747 cardiac effect Effects 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 238000012935 Averaging Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 230000004075 alteration Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 208000019622 heart disease Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000013519 translation Methods 0.000 description 2
- 208000020446 Cardiac disease Diseases 0.000 description 1
- 230000018199 S phase Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000013507 mapping Methods 0.000 description 1
- 229940127554 medical product Drugs 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 230000002966 stenotic effect Effects 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
- G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
- G01S15/88—Sonar systems specially adapted for specific applications
- G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
- G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
- G01S15/8979—Combined Doppler and pulse-echo imaging systems
- G01S15/8981—Discriminating between fixed and moving objects or between objects moving at different speeds, e.g. wall clutter filter
Definitions
- This invention relates to the field of ultrasound imaging and, in particular, to ultrasound imaging for medical diagnostic purposes. More specifically, the invention relates to improved signal filtering for use in cardiovascular ultrasound flow mapping, permitting improved discrimination between blood flow and heart wall motion.
- the first aspect is the angle between the flow velocity of interest and the incident ultrasound beam.
- the most accurate velocities are measured when the angle is very small.
- certain cardiac anomalies such as high-velocity jets caused by stenotic, regurgitant, or shunt lesions, or defects in the heart
- the exact angle of flow is unknown, and movement or rotation of the transducer is necessary until the location of the highest maximum velocity is obtained.
- the other important aspect of the equation is the proportional relationship between the frequency used to interrogate the blood flow and the resultant frequency shift. Due to this relationship, both pulsed Doppler and continuous-wave (CW) Doppler measurements are often employed.
- CW continuous-wave
- a typical prior art medical ultrasound imaging system employs a phased array transducer, a scanner unit and a signal processing and display unit.
- the scanner unit provides analog signal conditioning, beam forming and signal translation from the ultrasound range to a more convenient intermediate frequency (I.F.) range.
- I.F. intermediate frequency
- the processing and display unit then converts the analog I.F. signals to digital form and processes the digital samples in order to facilitate extraction and display of desired information contained in the transducer output.
- the display and processing unit may provide both black and white (monochrome) as well as color imaging.
- the monochrome mode typically is used to show anatomic detail, with blood flow shown in the color mode.
- a two-dimensional monochrome image may show a sector- (i.e., arcuately-) shaped scan region (i.e., volume) of a patient, displayed at a rate of approximately 30 frames per second.
- a color mode image may be overlaid on a portion (up to 100%) of the scanned sector, displacing the monochrome image.
- the monochrome signal or the color signal is displayed; alternatively, the two signals may be combined in some fashion.
- the color image is typically a color-coded blood flow map, where the color coding indicates localized velocity and turbulence of blood flow.
- velocity is shown in shades of red and blue, red indicating flow toward the transducer and blue indicating flow away from the transducer, or vice versa; sometimes another color may be mixed in over a portion of the scale, to focus attention on flows within selected ranges.
- the intensity and/or shading of the color represents the speed of the flow toward or away from the transducer. Shades of green are sometimes added to indicate turbulence.
- Velocity is measured using Doppler frequency shift techniques, which are well known. Turbulence is calculated, based on sample-to-sample consistency of velocities.
- the received (i.e., echoed) signal at the transducer output contains not only a Doppler shift component due to reflection from the moving blood, but also Doppler components due to reflections from the motion of tissue structures such as blood vessels, heart walls and valves.
- the heart wall is constantly in motion and is denser than the blood, it contributes a substantial Doppler signal which is significantly larger in amplitude (but generally lower in frequency) than the signal generated by the blood flow itself.
- a primary function of the signal processing and display unit is, therefore, to separate to the extent possible the signal due to the blood flow from other extraneous signals, such as those due to heart wall motion. (These extraneous signals may be termed "clutter.")
- the clutter rejection filter provides a frequency-dependent attenuation (or gain) of the received (i.e., returned echo) Doppler signal; the gain is higher for the blood flow signals (which are higher in frequency since blood flow is higher in velocity) than for the clutter signals.
- the received signal After the received signal has been thus filtered, it is sampled and velocity calculations are made from samples. Each computed velocity value is then "screened" against certain rejection (i.e., validation) criteria by the velocity sample rejection system.
- Velocities which have been determined from samples whose amplitudes (or at least one of whose amplitudes) are (is) below a predetermined acceptance/rejection threshold are considered unreliable and are therefore "discarded" by the velocity sample rejection system (i.e., they are neither displayed nor used in further calculations).
- the present invention provides an improved system for extracting blood flow information from "clutter" in a medical ultrasound system, to provide a better signal-to-noise ratio.
- the signal processing used in the velocity sample rejection system for separation the blood flow echo from the other Doppler components in the reflected signal, has used a simple, frequency-independent thresholding function. That is, any received signal sample having an amplitude below a selected threshold was discarded; the threshold was the same for all frequencies.
- the present inventio:n may utilize the same clutter rejection filter and velocity determination system as in the prior art (or any equivalent clutter rejection filter and velocity determination means).
- the present invention utilizes, in combination with these elements, a velocity sample rejection system which implements a velocity-dependent (i.e., frequency-dependent) rejection threshold. That is, the acceptance/rejection threshold is a function of frequency.
- the shape of the velocity-dependent thresholding function closely matches that of the attenuation transfer function of the clutter rejection filter.
- the rejection threshold is substantially lower than it is for high velocity samples.
- the rejection level increases monotonically as the signal deviates from the I.F.
- This type of frequency-dependent clutter and reject filtering has been found to improve the signal-to-noise ratio (i.e., clutter rejection) by about 12 dB, for the particular clutter rejection filter used in the HP,77020 system identified above.
- Fig. 1 there is shown a block diagram of a Doppler ultrasound system 10 of the type in which the present invention may be used.
- a Doppler ultrasound system 10 of the type in which the present invention may be used.
- One such prior art system which is commercially available is the model HP 77020 Phased Array Ultrasound System sold by Hewlett-Packard Company Medical Products Group, Andover, Massachusetts.
- the system employs a phased array ultrasound transducer 12, a scanner unit 14 and a processing and display unit 16.
- the scanner unit 14 generates the signals to control the transducer array 12 so as to generate a directed beam of ultrasonic energy, and receives (and optionally filters and amplifies) the echoes detected by the transducer array.
- the output of the transducer array is an analog Doppler shift signal centered about a predetermined frequency, the I.F.
- the output from the scanner unit 14 is supplied to processing and display unit (PDU) 16, a block diagram of which is shown in Figs. 2A and 2B.
- the first stage of the PDU is a variable gain amplifier 18; the gain of this amplifier is manually set by the operator.
- the output of the amplifier 18 is run though a bandpass I.F. filter 22.
- the I.F. filter 22 passes the complete range of intermediate frequencies, which typically may be from one to three megahertz. Although the filter 22 is used to optimize the signal-to-noise ratio of the returning echo, the Doppler signal has yet to be extracted.
- a sampling process is used to detect the Doppler shift and, hence, to determine the blood velocity at a given depth in the body of the patient.
- the output of the bandpass filter 22 is fed through a notch filter, not shown, in order to attenuate any signal component from the local oscillator for the transducer; such component(s) could interfere with the signal processing).
- the signal transmitted into the patient's body by the transducer contains energy only at the harmonics of the pulse repetition frequency (PRF).
- PRF pulse repetition frequency
- the returning echo contains components originating from two types of sources: stationary tissue and nonstationary tissue (including blood).
- the echoes from stationary tissue like the emitted signal, contain energy only at the PRF harmonics.
- the echoes from moving targets contain energy at frequencies shifted from the PRF harmonics by an amount proportional to the velocity of the target, as described by the Doppler equation. The system is designed to detect these frequency shifts.
- the sum of the two echo types (in the filtered I.F. output) is sampled by an analog-to-digital converter (ADC) 24, which then supplies complex samples.
- ADC analog-to-digital converter
- the timing of the sampling operation is controlled by a sampling clock supplied on line 26.
- PRI pulse repetition interval
- PRF pulse repetition interval
- the process of sampling can be restated as the translation and summing of each of the harmonics of the PRF and their immediate spectrums down to baseband.
- the spectrum is mirrored about the frequency PRF/2 (referred to as the Nyquist rate).
- PRF/2 referred to as the Nyquist rate
- quadrature sampling is often used.
- a pair of samplers is provided. A short time after a first one of the samplers take a sample, the second sampler takes another sample of the same signal. The delay between the two samplings is one-fourth the period of the I.F. The lead-lag phase relationship between the two sets of samples provides flow direction information. Additionally, the inclusion of the second sampler effectively doubles the Doppler bandwidth, allowing shifts from -Nyquist to +Nyquist frequencies to be distinguished.
- a conventional quadrature baseband mixing system may be used, sampling its output to produce the complex samples.
- a conventional clutter rejection filter 28 is used to reject unwanted Doppler signals.
- These unwanted signals are chiefly "wall signals" -- that is, reflections from the stationary or slowly moving heart and vessel walls as well as from the tissue between the transducer and the flow volume being interrogated.
- Such wall signals are typically 100 times as large as the echo received from the blood and are distinguished by having a much lower frequency Doppler shift than the echoes from the blood motion.
- the clutter rejection filter exploits this frequency separation to attenuate the low-frequency wall signals so they will not obscure the desired blood flow data.
- Fig. 3 shows in curve 40 a typical response for a clutter rejection filter.
- a Doppler processing system 32 then decodes the filtered signal to convert the "de-cluttered" Doppler frequency information into velocity information at each spatial point in the sampled volume. These raw velocity calculations are not immediately displayed. Rather, velocity samples are first separated into “good” samples and “bad” samples by a velocity sample rejection system. The “bad” samples are discarded, and a circular averager 33 uses only the "good” samples to generate the average velocity at each point.
- the averaging of velocity measures in stage 33 is a so-called “circular” averaging process which takes into account the fact that velocity is represented as a complex variable using modulo arithmetic.
- the averaged velocity data is supplied to an image memory and scan conversion subsystem 34 which generates the signals to control a display monitor 36 in order to show an image representing the measured blood flow in the sampled volume.
- the present invention is distinguished from the prior art in the particulars of the clutter rejection filtering and associated velocity sample rejection system, which uses a velocity-dependent threshold to distinguish between "goodness” and "badness” of velocity samples.
- the response of the prior art velocity sample rejection system is represented by the flat threshold function shown at line 42 in Fig. 3, superimposed on the clutter filter response curve 40. Note that the ordinate shows gain for the clutter rejection filter but amplitude for the rejection threshold function.
- the present invention employs a rejection threshold response as shown in Fig. 4 at curve 46.
- This rejection threshold function 46 is a frequency-dependent stepwise approximation to the clutter filter response 44.
- rejection threshold function 46 is shown as having four levels. That choice is for exemplification only, as the system designer may choose a different number of level without departing from the spirit of the invention.
- the locations of the threshold- level-transition points may be decided empirically.
- the velocity-dependent-rejection response of the present invention is accomplished by an apparatus which screens out (from further processing) velocity samples which do not meet the acceptability criteria -- i.e., are based on echoes whose amplitudes fall below the threshold function.
- velocity sample is somewhat of a misnomer; velocities are calculated, not sampled. Nevertheless, in the vernacular, each calculated velocity value is often called a sample.
- each velocity value Since the calculation of velocity is based on a differential phase measurement, each velocity value actually requires two signal samples.
- the acceptance or rejection of a velocity sample thus depends on the acceptability of the pair of signal samples used to calculate that velocity value.
- Each sample is a complex value -- i.e., it has both magnitude and phase. Consequently, the rejection criteria depends on four variables: two magnitudes and two phases. Stated another way, the rejection function depends on the amplitudes of the two echo samples and on the calculated velocity (since the phase difference divided by the sampling period gives the velocity).
- Figs. 2A and 2B The system providing this operation is shown in Figs. 2A and 2B.
- ROM 54 provides the phase (on line 55A) and magnitude (on line 55B) of each sample.
- This phase and magnitude information is stored in a temporary memory called a line buffer, 56.
- the system divides each scanned sector into a large number of consecutively adjacent scan lines. Each scan line is subdivided into a number of sample "points" (i.e., small volumes) at which localized Doppler measurements are taken.
- Line buffer 56 stores the samples for each line from one scan line to the next.
- a second ROM receives each current sample's phase and magnitude information on lines 55A and 55B from ROM 54 while receiving from line buffer 56 the comparable information for the previous sample at the same spatial location.
- the VRFG ROM has two jobs: it decodes the phase information to provide on line 62 a signal (VELOCITY) providing a velocity sample and it generates the velocity rejection function (the REJECT or rejection signal, for short) on line 64.
- the VELOCITY signal is calculated by dividing the inter-sample angular progression by the PRI.
- the REJECT signal is a binary signal provided in a first state to indicate that the rejection threshold was exceeded for the current sample (i e., the sample is "good"), and in a second state to indicate that the reject threshold was not exceeded (i.e., the sample is "bad”.) .
- the REJECT signal is said to be "asserted” or "present”.
- the circular averaging stage 66 receives both outputs from VRFG ROM 60; however, it only processes those samples of the VELOCITY signal for which the REJECT signal is not asserted, That is, when the REJECT signal is asserted. the velocity value on line 62 is ignored or discarded; it is not averaged with prior velocity samples and it is not displayed.
- Fig. 5 depicts a high-level flow chart for the operation of the angle and magnitude conversion ROM 54.
- step 82 the real and imaginary data portions of a Doppler sample are received, each coded as seven bits.
- the vector magnitude (MAGVEC) of the sample is then computed in step 84 as the square root of the sum of the squares of the real and imaginary data.
- the magnitude is then encoded (in step 86) to a two-bit variable, MAGREJ.
- the angle of the sample vector is evaluated (in step 88) to a five-bit variable, VALUE.
- the number of bits used for each variable is to some degree a matter of design choice.
- Fig. 6 provides a high-level flow chart for the operation of the VRFG ROM 60.
- the inputs to this ROM are a pair of five-bit angle values termed NEWANGLE (for the new, or current, sample) and OLDANGLE (for the preceding scan's sample, from the line buffer), and a pair of corresponding two-bit magnitude values labelled, respectively, MAGVEC1 (for the current sample) and MAGVEC2 (for the preceding sample).
- NEWANGLE for the new, or current, sample
- OLDANGLE for the preceding scan's sample, from the line buffer
- MAGVEC1 for the current sample
- MAGVEC2 for the preceding sample.
- DELTA is encoded into a corresponding five-bit velocity value, VELOCITY (step 96).
- VELOCITY DELTA/PRI.
- REJECT rejection signal
- That function serves the purpose of asserting the REJECT signal if for a given value of VELOCITY, either MAGVEC1 or MAGVEC2 is below the threshold level established for that velocity range.
- the rejection function is defined by the shaded area 49 under the dashed threshold line 46.
- the ordinate in Fig. 4 represents the amplitude of the echoes, which become encoded as MAGVEC1 and MAGVEC2 values.
- the REJECT signal is asserted if either MAGVEC1 or MAGVEC2 is less than T1.
- the threshold increases to T2, and so forth.
- the system can look first at the lesser of MAGVEC1 and MAGVEC2 and then check to ensure that the corresponding frequencies are in the range where those amplitudes are acceptable.
- the VELOCITY and REJECT signals on lines 62 and 64 are also applied to a turbulence calcuator 102, which calculates a measure of the dispersion in values between successive samples at the same spatial location.
- the turbulence calculator is controlled by the REJECT signal, to ignore velocity samples not passing the rejection criteria.
- the turbulence calculation is supplied along with the circular averages to an optional spatial filter 104.
- the spatial filter can be a median filter, averaging filter, or other type of filter for enhancing the image.
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- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Radar, Positioning & Navigation (AREA)
- Remote Sensing (AREA)
- Acoustics & Sound (AREA)
- Computer Networks & Wireless Communication (AREA)
- General Physics & Mathematics (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Measuring Volume Flow (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/119,754 US4850364A (en) | 1987-11-12 | 1987-11-12 | Medical ultrasound imaging system with velocity-dependent rejection filtering |
US119754 | 1987-11-12 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0316200A2 true EP0316200A2 (de) | 1989-05-17 |
EP0316200A3 EP0316200A3 (en) | 1990-03-28 |
EP0316200B1 EP0316200B1 (de) | 1993-08-25 |
Family
ID=22386174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP88310686A Expired - Lifetime EP0316200B1 (de) | 1987-11-12 | 1988-11-11 | Medizinisches Ultraschallabbildungssystem |
Country Status (4)
Country | Link |
---|---|
US (1) | US4850364A (de) |
EP (1) | EP0316200B1 (de) |
JP (1) | JP2738939B2 (de) |
DE (1) | DE3883484T2 (de) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0492054A2 (de) * | 1990-12-20 | 1992-07-01 | Hewlett-Packard Company | Adaptives Sperrfilter zur farblichen Darstellung von Strömungen in der Ultraschallbildtechnik |
EP0524774A2 (de) * | 1991-07-25 | 1993-01-27 | Matsushita Electric Industrial Co., Ltd. | Bildgebener Ultraschall-Doppler-Apparat |
WO1994016341A1 (en) * | 1993-01-08 | 1994-07-21 | General Electric Company | Color flow imaging system utilizing a time domain adaptive wall filter |
WO1994020866A1 (en) * | 1993-03-01 | 1994-09-15 | General Electric Company | Wall filter using circular convolution for a color flow imaging system |
WO2006096915A1 (en) * | 2005-03-15 | 2006-09-21 | Uscom Limited | Automatic flow tracking system and method |
EP2397867A1 (de) * | 2010-06-17 | 2011-12-21 | Samsung Medison Co., Ltd. | Adaptive Clutterfiltrierung in einem Ultraschallsystem |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0379139B1 (de) * | 1989-01-17 | 1994-07-27 | Fujitsu Limited | Ultraschalldiagnosegerät |
JPH03188841A (ja) * | 1989-09-20 | 1991-08-16 | Toshiba Corp | 超音波診断装置 |
US5197477A (en) * | 1990-10-12 | 1993-03-30 | Advanced Technology Laboratories, Inc. | Ultrasonic doppler flow measurement system with tissue motion discrimination |
US5419331A (en) * | 1994-02-10 | 1995-05-30 | The University Of Rochester | System for estimating target velocity from pulse echoes in response to their correspondence with predetermined delay trajectories corresponding to different distinct velocities |
US5429137A (en) * | 1994-06-03 | 1995-07-04 | Siemens Medical Systems, Inc. | Acoustic scan conversion method and apparatus for velocity flow |
US5515852A (en) * | 1994-06-06 | 1996-05-14 | Hewlett-Packard Company | Method and apparatus for a detection strength spatial filter in an ultrasound imaging system |
US5640960A (en) * | 1995-04-18 | 1997-06-24 | Imex Medical Systems, Inc. | Hand-held, battery operated, doppler ultrasound medical diagnostic device with cordless probe |
US5634465A (en) * | 1995-06-09 | 1997-06-03 | Advanced Technology Laboratories, Inc. | Continuous display of cardiac blood flow information |
US6001063A (en) * | 1998-06-23 | 1999-12-14 | Acuson Corporation | Ultrasonic imaging method and apparatus for providing doppler energy correction |
US20030078227A1 (en) * | 1998-07-02 | 2003-04-24 | Greenleaf James F. | Site-directed transfection with ultrasound and cavitation nuclei |
US6146331A (en) * | 1998-09-30 | 2000-11-14 | Siemens Medical Systems, Inc. | Method for improved clutter suppression for ultrasonic color doppler imaging |
US6370264B1 (en) | 1999-04-07 | 2002-04-09 | Steven C Leavitt | Method and apparatus for ultrasonic color flow imaging |
US7555333B2 (en) | 2000-06-19 | 2009-06-30 | University Of Washington | Integrated optical scanning image acquisition and display |
EP1691666B1 (de) | 2003-12-12 | 2012-05-30 | University of Washington | Katheterskop-3d-führung und schnittstellensystem |
US7530948B2 (en) | 2005-02-28 | 2009-05-12 | University Of Washington | Tethered capsule endoscope for Barrett's Esophagus screening |
US8537203B2 (en) * | 2005-11-23 | 2013-09-17 | University Of Washington | Scanning beam with variable sequential framing using interrupted scanning resonance |
US20070213618A1 (en) * | 2006-01-17 | 2007-09-13 | University Of Washington | Scanning fiber-optic nonlinear optical imaging and spectroscopy endoscope |
US9561078B2 (en) | 2006-03-03 | 2017-02-07 | University Of Washington | Multi-cladding optical fiber scanner |
US20070216908A1 (en) * | 2006-03-17 | 2007-09-20 | University Of Washington | Clutter rejection filters for optical doppler tomography |
US8840566B2 (en) | 2007-04-02 | 2014-09-23 | University Of Washington | Catheter with imaging capability acts as guidewire for cannula tools |
CN101636113B (zh) * | 2007-04-27 | 2011-09-21 | 株式会社日立医药 | 超声波诊断装置 |
US7952718B2 (en) | 2007-05-03 | 2011-05-31 | University Of Washington | High resolution optical coherence tomography based imaging for intraluminal and interstitial use implemented with a reduced form factor |
EP3600061A1 (de) * | 2017-03-31 | 2020-02-05 | Koninklijke Philips N.V. | Messungen von intravaskulärem durchfluss und druck |
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EP0298569A1 (de) * | 1987-07-09 | 1989-01-11 | Laboratoires D'electronique Philips | Gerät zum Ausschliessen von Festechos für Ultraschallechographie |
EP0225667B1 (de) * | 1985-12-03 | 1993-02-10 | Laboratoires D'electronique Philips | Gerät zur Ultraschallechographie der Bewegung von Körperorganen, insbesondere der Blutströmung oder des Herzens |
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JPS5920820A (ja) * | 1982-07-28 | 1984-02-02 | Aloka Co Ltd | 超音波血流画像形成装置 |
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-
1987
- 1987-11-12 US US07/119,754 patent/US4850364A/en not_active Expired - Lifetime
-
1988
- 1988-11-11 EP EP88310686A patent/EP0316200B1/de not_active Expired - Lifetime
- 1988-11-11 JP JP63285615A patent/JP2738939B2/ja not_active Expired - Lifetime
- 1988-11-11 DE DE88310686T patent/DE3883484T2/de not_active Expired - Fee Related
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US3934577A (en) * | 1972-12-08 | 1976-01-27 | Hoffmann-La Roche Inc. | Fetal heart rate monitoring apparatus |
EP0081045A1 (de) * | 1981-12-03 | 1983-06-15 | Kabushiki Kaisha Toshiba | Ultraschall diagnoseanlage |
EP0137317A2 (de) * | 1983-09-08 | 1985-04-17 | Matsushita Electric Industrial Co., Ltd. | Ultraschallgerät zur Blutströmungsmessung |
US4660565A (en) * | 1983-12-08 | 1987-04-28 | Kabushiki Kaisha Toshiba | Ultrasonic imaging apparatus using pulsed Doppler signal |
US4651745A (en) * | 1984-04-02 | 1987-03-24 | Aloka Co., Ltd. | Ultrasonic Doppler diagnostic device |
EP0202920A2 (de) * | 1985-05-20 | 1986-11-26 | Matsushita Electric Industrial Co., Ltd. | Blutgeschwindigkeitsmesser nach dem Ultraschall-Doppler-Prinzip |
EP0225667B1 (de) * | 1985-12-03 | 1993-02-10 | Laboratoires D'electronique Philips | Gerät zur Ultraschallechographie der Bewegung von Körperorganen, insbesondere der Blutströmung oder des Herzens |
EP0266998A2 (de) * | 1986-11-03 | 1988-05-11 | Hewlett-Packard Company | Gerät zum Sichtbarmachen von Strömung |
EP0298569A1 (de) * | 1987-07-09 | 1989-01-11 | Laboratoires D'electronique Philips | Gerät zum Ausschliessen von Festechos für Ultraschallechographie |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0492054A2 (de) * | 1990-12-20 | 1992-07-01 | Hewlett-Packard Company | Adaptives Sperrfilter zur farblichen Darstellung von Strömungen in der Ultraschallbildtechnik |
EP0492054A3 (en) * | 1990-12-20 | 1993-02-24 | Hewlett-Packard Company | Adaptive rejection filter for colour flow ultrasound imaging |
EP0524774A2 (de) * | 1991-07-25 | 1993-01-27 | Matsushita Electric Industrial Co., Ltd. | Bildgebener Ultraschall-Doppler-Apparat |
EP0524774A3 (en) * | 1991-07-25 | 1994-12-07 | Matsushita Electric Ind Co Ltd | Ultrasonic doppler imaging apparatus |
WO1994016341A1 (en) * | 1993-01-08 | 1994-07-21 | General Electric Company | Color flow imaging system utilizing a time domain adaptive wall filter |
WO1994020866A1 (en) * | 1993-03-01 | 1994-09-15 | General Electric Company | Wall filter using circular convolution for a color flow imaging system |
WO2006096915A1 (en) * | 2005-03-15 | 2006-09-21 | Uscom Limited | Automatic flow tracking system and method |
EP2397867A1 (de) * | 2010-06-17 | 2011-12-21 | Samsung Medison Co., Ltd. | Adaptive Clutterfiltrierung in einem Ultraschallsystem |
US9107602B2 (en) | 2010-06-17 | 2015-08-18 | Samsung Medison Co., Ltd. | Adaptive clutter filtering in an ultrasound system |
Also Published As
Publication number | Publication date |
---|---|
EP0316200B1 (de) | 1993-08-25 |
JPH01164355A (ja) | 1989-06-28 |
JP2738939B2 (ja) | 1998-04-08 |
DE3883484D1 (de) | 1993-09-30 |
US4850364A (en) | 1989-07-25 |
EP0316200A3 (en) | 1990-03-28 |
DE3883484T2 (de) | 1994-03-24 |
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