EP0282444A1 - Beatmungsturm in Modulbauweise für Labortiere - Google Patents

Beatmungsturm in Modulbauweise für Labortiere Download PDF

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Publication number
EP0282444A1
EP0282444A1 EP88810066A EP88810066A EP0282444A1 EP 0282444 A1 EP0282444 A1 EP 0282444A1 EP 88810066 A EP88810066 A EP 88810066A EP 88810066 A EP88810066 A EP 88810066A EP 0282444 A1 EP0282444 A1 EP 0282444A1
Authority
EP
European Patent Office
Prior art keywords
annular
inhalation
external
duct
holes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP88810066A
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English (en)
French (fr)
Other versions
EP0282444B1 (de
Inventor
David M. Bernstein
Hermut Fleissner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RESEARCH AND CONSULTING CO AG
Original Assignee
RESEARCH AND CONSULTING CO AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RESEARCH AND CONSULTING CO AG filed Critical RESEARCH AND CONSULTING CO AG
Priority to AT88810066T priority Critical patent/ATE68088T1/de
Publication of EP0282444A1 publication Critical patent/EP0282444A1/de
Application granted granted Critical
Publication of EP0282444B1 publication Critical patent/EP0282444B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A61D7/04—Devices for anaesthetising animals by gases or vapours; Inhaling devices

Definitions

  • the present invention relates to a modular inhalation tower for laboratory animals comprising two concentric vertical conduits around the vertical axis of this tower which comprises several stages each of which has a tray for supporting individual inhalation chambers and conduits of radial connections, grouped by stages and distributed equiangularly on each stage, to connect each inhalation chamber to the internal central distribution conduit, the external central conduit for evacuating the inhaled gas having openings concentric with each of said connection conduits in communication with each of said inhalation chambers with the external central exhaust duct.
  • the aerosol is distributed continuously through a small tube to the nose of each animal and is aspirated at the exit of this tube without having come into contact with other parts of the body. animal or with other animals.
  • the creation of a modular inhalation tower with a support tray on each floor was proposed in a technical note published in the spring of 1986 by the Geneva research center of the Battelle Memorial Institute.
  • the object of the present invention is precisely the production of such a modular inhalation tower which has a very large capacity with a space requirement reduced to a minimum.
  • the inhalation tower proposed in the technical note mentioned above was made of PVC, the increase in capacity creates heating problems and therefore heat dissipation which required the use of metal to allow better evacuation of heat by simple convection with ambient air. This change in material led to modifications in the construction of the cooling tower.
  • the present invention relates to an inhalation tower as defined by claim 1.
  • This inhalation tower has two vertical coaxial ducts 1,2 which form a column which carries a series of circular plates 3 regularly spaced and each defining a stage intended to receive individual inhalation chambers 4.
  • These chambers are generally tubular in shape ending in a front part in the shape of a rectangular truncated cone 4a, which ends at a cylindrical end 4b, intended to engage in a housing 5 formed in the wall of the external conduit 2, an O-ring seal 6 being in a groove in the cylindrical wall of the housing 5.
  • the bottom of this housing 5 is pierced with an opening 7 which puts it in communication with the interior of the external conduit 2 and which lets a distribution pipe 8 pass through its center which is screwed into the wall of the internal duct 1.
  • Each of the internal conduits 1 and external 2 constituting the column is formed of nested segments 11 respectively 12 whose width corresponds to the height of a stage of the inhalation tower.
  • the upper end of each segment 11 and 12 has an external annular bearing surface 9 respectively 10 while the lower ends of these segments 11 and 12 comprise internal annular bearing surfaces 13, respectively 14.
  • the respective diameters of the external bearing surfaces 9 and 10 are complementary to the respective diameters of the internal surfaces so that the lower ends of the respective segments 11 and 12 can be fitted on the upper ends of the respective adjacent segments.
  • the height of the internal surface 14 of the external segment 12 is less than that of the external surface 10 of this same segment, thus providing an annular space intended to receive the internal edge of a circular plate 3.
  • the external face of the external conduit 2 has an annular clearance 15 which extends between the stage of housings 5 and the external bearing 10, providing an annular projection 16 adjacent to the external bearing 10.
  • Four equidistant bores 17 are formed perpendicular to the plane of this annular projection 16. They correspond to four threads 18 formed perpendicular to the plane of the opposite end face of the same segment 12.
  • An angular offset corresponding to a half pitch separating the housings 5 exists between the holes 17 passing through the annular projection 16 and the threads 18 formed at the other end, so that the successive rows of housings are offset by half a step with respect to each other.
  • the circular plates 3 also include four equidistant holes intended to correspond to the holes 17 and the threads 18.
  • a screw 19 is introduced into each of the threads 18 through the respective holes 17 and the holes of the circular plate 3, thus making all the segments 2 and the trays 3 secured to each other over the entire height of the inhalation tower.
  • This disc 20 is fixed in its center to a disc of smaller diameter 23 which adapts to a central opening of the support frame 21.
  • a supply pipe 24 is rotatably mounted in the center of the disc 23.
  • a closed space 25 is formed between the two discs 20 and 23. This space 25 communicates with the collector of gas inhaled by animals, formed between the internal and external conduits 1 and 2 by holes 26 formed through the disc 20.
  • a hole of smaller diameter 27 passes through the center of the disc 20 and is intended for the complete evacuation of the water during cleaning.
  • the central column is closed by a flange 28 which adjusts on the external 12 and internal 11 segments and which carries a feed tube 29 mounted rotatably in its center.
  • This tube 29 is intended to be connected to a source of gas or aerosol to be inhaled. Since the flange fits over the ends of the two segments 11 and 12, the gas or aerosol leaving the tube 29 is introduced into the internal conduit 1.
  • Each of the plates comprises a circlar rib 30 for the radial positioning of the inhalation chambers 4 which each comprises a pair of projections 4c intended to engage inside this circular rib 30. Outside this rib 30, the plate 3 comprises an annular channel 31 intended to collect the urine and the excrement of the animals.
  • the inhalation tower which has just been described has many advantages. Its capacity according to its volume is high, its modular design allows to adapt the height of the tower according to the needs. This modular design also offers a great advantage for cleaning.
  • the heat released by the dozens of animals that this tower can receive can be evacuated by natural convection between the ambient air and the metal parts that make up this tower.
  • the rotary mounting of this tower on its support also saves space, insofar as it is not necessary to have access to this tower over its entire periphery but only over part of it.

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Housing For Livestock And Birds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Duct Arrangements (AREA)
EP88810066A 1987-02-09 1988-02-05 Beatmungsturm in Modulbauweise für Labortiere Expired - Lifetime EP0282444B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT88810066T ATE68088T1 (de) 1987-02-09 1988-02-05 Beatmungsturm in modulbauweise fuer labortiere.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH475/87A CH670378A5 (de) 1987-02-09 1987-02-09
CH475/87 1987-02-09

Publications (2)

Publication Number Publication Date
EP0282444A1 true EP0282444A1 (de) 1988-09-14
EP0282444B1 EP0282444B1 (de) 1991-10-09

Family

ID=4187850

Family Applications (1)

Application Number Title Priority Date Filing Date
EP88810066A Expired - Lifetime EP0282444B1 (de) 1987-02-09 1988-02-05 Beatmungsturm in Modulbauweise für Labortiere

Country Status (6)

Country Link
US (1) US4860741A (de)
EP (1) EP0282444B1 (de)
JP (1) JPS63194653A (de)
AT (1) ATE68088T1 (de)
CH (1) CH670378A5 (de)
DE (1) DE3865326D1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109797A (en) * 1990-08-29 1992-05-05 Briant James K Avian inhalation exposure chamber
US5099792A (en) * 1991-04-08 1992-03-31 Battelle Memorial Institute Interchangeable whole-body and nose-only exposure system
US5297502A (en) * 1993-05-05 1994-03-29 Jaeger Rudolf J Modular reversible-flow-past nasopulmonary respiratory dosing system for laboratory animals
US6725859B1 (en) * 1997-01-22 2004-04-27 Charles River Laboratories Apparatus for delivering air-borne substances
US7377276B2 (en) * 2001-01-31 2008-05-27 United States Of America As Represented By The Secretary Of The Army Automated inhalation toxicology exposure system and method
US6904912B2 (en) * 2001-01-31 2005-06-14 The United States Of America As Represented By The Secretary Of The Army Automated inhalation toxicology exposure system
US8221329B2 (en) * 2001-07-31 2012-07-17 The United State Of America As Represented By The Secretary Of The Army Inhalation system and method
US6651587B1 (en) 2002-03-29 2003-11-25 Battelle Memorial Institute Container for containing an experimental test animal
FR2879094B1 (fr) * 2004-12-10 2007-10-26 Equip Veterinaire Minerve Sa Dispositif d'induction directe de gaz anesthesiants pour rongeur, associe a une cellule d'isolement securisee et transferable vers une unite d'acquisition de donnees en imagerie medicale
CA2652925A1 (fr) * 2006-05-24 2007-11-29 Equipement Veterinaire Minerve Cellule universelle pour l'imagerie medicale d'un petit animal sous anesthesie
JP4885102B2 (ja) * 2007-09-28 2012-02-29 富士フイルム株式会社 ノーズマスク
US20090223460A1 (en) * 2008-03-10 2009-09-10 Starr Life Sciences Corp. Bioactive gas supply chamber for animal research such as hypoxia studies on non-anesthetized small animals with direct physiologic monitoring
WO2010002331A1 (en) * 2008-07-04 2010-01-07 Astrazeneca Ab Apparatus and method for exposing laboratory animals to a test substance
US9408682B2 (en) * 2009-04-27 2016-08-09 Rapid Biomedical Gmbh Animal imaging holding device and method
US9180263B2 (en) * 2009-07-01 2015-11-10 Microdose Therapeutx, Inc. Laboratory animal pulmonary dosing device
WO2011014908A1 (en) * 2009-08-03 2011-02-10 Colin Dunlop An improved method and apparatus for delivering a fluid to a patient
CN101803962B (zh) * 2010-04-23 2011-10-05 中国人民解放军军事医学科学院微生物流行病研究所 一种啮齿动物口鼻吸入动态暴露装置
US9320453B2 (en) 2011-05-06 2016-04-26 Rapid Biomedical Gmbh Assembly to perform imaging on rodents
CN104586533B (zh) * 2014-08-01 2016-04-27 南通大学 实验操作简单易行、经过滤的内外式一氧化碳中毒装置
US20170312066A1 (en) * 2015-11-30 2017-11-02 The University Of Notre Dame Du Lac Versatile inhalation anesthesia platform for small animal surgery
WO2017136856A1 (en) 2016-02-07 2017-08-10 U.S. Government As Represented By The Secretary Of The Army Oro-nasal inhalation plethysmography mask exposure system
WO2017136855A1 (en) 2016-02-07 2017-08-10 Haupt Brett Head-only and/or whole body inhalation exposure chamber
CN105476728A (zh) * 2016-02-15 2016-04-13 赵菁 一种诱发小鼠心肺血管疾病的实验装置
US10820566B2 (en) * 2016-05-27 2020-11-03 Animal Care Systems, Inc. Animal cage environmental systems and methods
US11084046B2 (en) 2016-10-03 2021-08-10 The Government Of The United States, As Represented By The Secretary Of The Army Aerosol concentrating apparatus for use with aerosol aging drum

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1507065A1 (de) * 1965-12-14 1969-06-19 Rudolf Bruenger Kaefig fuer Kleintiere
EP0053253A2 (de) * 1980-11-27 1982-06-09 BASF Aktiengesellschaft Inhalationsapparatur für Versuchstiere
EP0121795A2 (de) * 1983-03-10 1984-10-17 Stauffer Chemical Company Gerät zur Inhalation von Testgas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3548840A (en) * 1967-10-30 1970-12-22 Gallaher Ltd Cigarette smoking machines
SU1014543A1 (ru) * 1981-05-20 1983-04-30 Ордена Трудового Красного Знамени Институт Физиологии Им.А.А.Богомольца Устройство дл сбора экскрементов у лабораторных животных
US4721060A (en) * 1986-07-17 1988-01-26 Battelle Memorial Institute Nose-only exposure system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1507065A1 (de) * 1965-12-14 1969-06-19 Rudolf Bruenger Kaefig fuer Kleintiere
EP0053253A2 (de) * 1980-11-27 1982-06-09 BASF Aktiengesellschaft Inhalationsapparatur für Versuchstiere
EP0121795A2 (de) * 1983-03-10 1984-10-17 Stauffer Chemical Company Gerät zur Inhalation von Testgas

Also Published As

Publication number Publication date
CH670378A5 (de) 1989-06-15
EP0282444B1 (de) 1991-10-09
JPS63194653A (ja) 1988-08-11
US4860741A (en) 1989-08-29
ATE68088T1 (de) 1991-10-15
DE3865326D1 (de) 1991-11-14

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