EP0247428A3 - Carbohydrate containing dichloromethylenimino radicals, and method for their preparation - Google Patents

Carbohydrate containing dichloromethylenimino radicals, and method for their preparation Download PDF

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Publication number
EP0247428A3
EP0247428A3 EP87106837A EP87106837A EP0247428A3 EP 0247428 A3 EP0247428 A3 EP 0247428A3 EP 87106837 A EP87106837 A EP 87106837A EP 87106837 A EP87106837 A EP 87106837A EP 0247428 A3 EP0247428 A3 EP 0247428A3
Authority
EP
European Patent Office
Prior art keywords
preparation
dichloromethylenimino
radicals
carbohydrate containing
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP87106837A
Other languages
German (de)
French (fr)
Other versions
EP0247428A2 (en
Inventor
Tillmann Dr. Hassel
Hanns Peter Dr. Müller
Gerhard Dr. Bonse
Oswald Dr. Lockhoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of EP0247428A2 publication Critical patent/EP0247428A2/en
Publication of EP0247428A3 publication Critical patent/EP0247428A3/en
Withdrawn legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)

Abstract

Die Erfindung betrifft neue Zucker, die eine Isocyaniddi­ chlorid-Gruppe an eines der nicht-anomeren C-Atome des Zuckermoleküls gebunden enthalten und ihre Herstellung durch Chlorieren von Zuckern, die eine Isonitrilgruppe an eines der nicht-anomeren C-Atome des Zuckermoleküls gebunden enthalten. The invention relates to new sugars which is an isocyanide di chloride group on one of the non-anomeric carbon atoms of the Contained sugar molecule bound and their preparation by chlorination of sugars that have an isonitrile group one of the non-anomeric carbon atoms of the sugar molecule bound included.

EP87106837A 1986-05-23 1987-05-12 Carbohydrate containing dichloromethylenimino radicals, and method for their preparation Withdrawn EP0247428A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863617272 DE3617272A1 (en) 1986-05-23 1986-05-23 SUGARS HAVING ISOCYANIDE DICHLORIDE GROUPS AND METHOD FOR THE PRODUCTION THEREOF
DE3617272 1986-05-23

Publications (2)

Publication Number Publication Date
EP0247428A2 EP0247428A2 (en) 1987-12-02
EP0247428A3 true EP0247428A3 (en) 1989-11-15

Family

ID=6301410

Family Applications (1)

Application Number Title Priority Date Filing Date
EP87106837A Withdrawn EP0247428A3 (en) 1986-05-23 1987-05-12 Carbohydrate containing dichloromethylenimino radicals, and method for their preparation

Country Status (4)

Country Link
EP (1) EP0247428A3 (en)
JP (1) JPS62283991A (en)
DE (1) DE3617272A1 (en)
IL (1) IL82593A0 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476924A (en) * 1989-01-27 1995-12-19 Duke University Protecting group for acetals and methods of using the same in the activation of saccharides

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3575959A (en) * 1969-05-13 1971-04-20 Merck & Co Inc 5'-substituted ribofuranosyl nucleosides
JPS5175072A (en) * 1974-12-18 1976-06-29 Tokyo Tanabe Co RIBOFURANOOZUNONITOROSOKARUBAMIRUJUDOTAINO SEIZOHO
JPS56103196A (en) * 1980-01-21 1981-08-18 Wakamoto Pharmaceut Co Ltd Preparation of d-glucose derivative
JPS56103197A (en) * 1980-01-21 1981-08-18 Wakamoto Pharmaceut Co Ltd Novel d-glucose derivative and antitumor agent containing the same as active constitutent
EP0171016A2 (en) * 1984-08-10 1986-02-12 Bayer Ag Cyclic ethers alpha-substituted by an isocyanide dichloride group, and method for their preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3575959A (en) * 1969-05-13 1971-04-20 Merck & Co Inc 5'-substituted ribofuranosyl nucleosides
JPS5175072A (en) * 1974-12-18 1976-06-29 Tokyo Tanabe Co RIBOFURANOOZUNONITOROSOKARUBAMIRUJUDOTAINO SEIZOHO
JPS56103196A (en) * 1980-01-21 1981-08-18 Wakamoto Pharmaceut Co Ltd Preparation of d-glucose derivative
JPS56103197A (en) * 1980-01-21 1981-08-18 Wakamoto Pharmaceut Co Ltd Novel d-glucose derivative and antitumor agent containing the same as active constitutent
EP0171016A2 (en) * 1984-08-10 1986-02-12 Bayer Ag Cyclic ethers alpha-substituted by an isocyanide dichloride group, and method for their preparation

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Band 86, Nr 1, 3. Januar 1977, Seite 451, Zusammenfassung Nr. 16911j, Columbus, Ohio, US; & JP-A-51 075 072 (TOKYO TANABE CO., LTD) 29-06-1976 *
CHEMICAL ABSTRACTS, Band 96, Nr. 3, 18. Januar 1982, Seite 488, Zusammenfassung Nr. 20428f, Columbus, Ohio, US; & JP-A-56 103 196 (WAKAMOTO PHARMACEUTICAL CO., LTD) 18-08-1981 *
CHEMICAL ABSTRACTS, Band 96, Nr. 3, 18. Januar 1982, Seite 488, Zusammenfassung Nr. 20429g, Columbus, Ohio, US; & JP-A-56 103 197 (WAKAMOTO PHARMACEUTICAL CO., LTD) 18-08-1981 *
H. ULRICH: "The Chemistry of Imidoyl Halides", 1968, Seiten 13-55, Plenum Press, New York, US, Kapitel 2: "Carbonimidoyl Dihalides" *

Also Published As

Publication number Publication date
JPS62283991A (en) 1987-12-09
IL82593A0 (en) 1987-11-30
EP0247428A2 (en) 1987-12-02
DE3617272A1 (en) 1987-11-26

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: BONSE, GERHARD, DR.

Inventor name: MUELLER, HANNS PETER, DR.

Inventor name: HASSEL, TILLMANN, DR.

Inventor name: LOCKHOFF, OSWALD, DR.