EP0208787A1 - Micro-tube medical de guidage - Google Patents
Micro-tube medical de guidage Download PDFInfo
- Publication number
- EP0208787A1 EP0208787A1 EP86900633A EP86900633A EP0208787A1 EP 0208787 A1 EP0208787 A1 EP 0208787A1 EP 86900633 A EP86900633 A EP 86900633A EP 86900633 A EP86900633 A EP 86900633A EP 0208787 A1 EP0208787 A1 EP 0208787A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- balloon
- tube
- tip
- outlet hole
- fluid outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/0069—Tip not integral with tube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
- A61M25/0075—Valve means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/7722—Line condition change responsive valves
- Y10T137/7837—Direct response valves [i.e., check valve type]
- Y10T137/7879—Resilient material valve
- Y10T137/7888—With valve member flexing about securement
Definitions
- the present invention relates to guiding microtubes for inserting into blood vessel.
- the catheter .used for injecting therapeutic liquid into lesion on blood vessel has been used by firstly introducing a guide wire thereof within the blood vessel near the lesion and then inserting it along the outer wall of the guide wire.
- a metal guide wire of stainless steel and stainless steel coil has been used and has drawbacks such as liability to injuring the inner wall of blood vessel during operation.
- Recently so called flow guide wire, of which tip is floated on the blood flow and introduced into peripheral blood vessels, has been proposed, but it also has drawbacks, for example, in which the structure is so fine that it is difficult to pass through such blood vessels having many windings and bendings and it is substantially impossible to introduce it up to lesion of peripheral blood vessels.
- a guide catheter which can perform the roles of both catheter and guide wire and well known leak balloon catheter have drawbacks, for example, the liability to injuring the inner wall of blood vessels, the difficulty of passing through peripheral blood vessels and the instability of the operation.
- the object of the present invention is to present a flow guide wire and/or a flow guide catheter (called as a guiding microtube hereinunder) which improve the disadvantages of the above prior art.
- Another object of the present invention is to present a flow guide wire which can be selectively introduced into peripheral blood vessels by simple handling in short time and be easily withdrawn and further be handled very safely.
- Another object of the present invention is to present a flow guide catheter particularly a leak balloon catheter which can easily be introduced into peripheral blood vessels and be handled safely by controlling the infusion of therapeutic liquid easily and certainly.
- the fundamental structure of the guiding microtube of the present invention is a cylindrical or spheroidal balloon which is projectingly attached to the tip of a plastic tube.
- the guiding microtube of the present invention comprises a plastic tube having a fluid outlet hole at the tip of the tube and a fluid inlet hole near the rear end of the plastic tube, said plastic tube having optionally fine tip portion, thick operational portion and taper portion connecting both, making an inside portion of said tube a fluid transfer channel, said channel optionally containing non-X ray transmission material said inside portion so that the function of said fluid transfer channel is maintained, attaching a cylindrical or spheroidal balloon at the tip of said tube so as to interconnect the lumen of said balloon with said fluid outlet hole, optionally providing a fluid outlet hole at the tip of said balloon and providing a valve mechanism within the lumen of said balloon when the fluid outlet hole is provided at the tip of said balloon.
- the guiding microtube of the present invention may perform function of a flow guide wire and/or a leak balloon catheter.
- said tube When used as the flow guide wire, said tube has a slender tip portion, a thick operational portion and taper portion interconnecting them, and contains non-X ray transmission material within it.
- a fluid outlet hole is provided to the balloon having a valve mechanism.
- Said valve mechanism comprises a movable stopper which is engaged with the catheter, and said stopper makes said outlet hole of therapeutic liquid open or close according to the transformation of said balloon caused by the change of the inner pressure of said balloon to form a valve mechanism.
- F ig.1(a) shows an elevational cross sectional view of the fundamental structure of the flow guide wire of the present invention
- Figs.1(b) and (c) show cross sectional views of Fig.1(a) at part A-A' and part B-B', respectively.
- the flow guide wire of the present invention comprises a plastic tube 1 having an empty portion 2 which is opened throughly, non-X ray transmission material 3 and a balloon 4.
- the tube 1 from its tip to the rear end, there are a slender aad flexible tip portion 10, a taper portion 11 and a relatively thick and hard operational portion 12 successiveively.
- the non-X ray transmission material 3 is inserted into the empty portion 2 from the rear end of the operational portion 12 to the taper portion 11, being fixed at the rear end of the operational portion 12 by any method.
- a fluid outlet hole 13 is provided at the tip of the tube 1 and a fluid inlet hole 5 at the rear end thereof: and at the end of flexible tip portion 10 a elastic balloon 4 containing non-X ray transmission material 3' is attached independently and projectingly, and the lumen 7 of said balloon is interconnected with the fluid inlet hole 5, the fluid outlet hole 13 and the fluid transfer channel 6.
- fluid inlet hole 5 is capped and preferably may be connected with a connector or an injector.
- Fig.2 is an elevation cross sectional view of another embodiment of the balloon, and in this case, a balloon 4 is cylindrical, its tip being closed with non-X ray transmission material 3' fixed with fiber 8' and adhesive 9' etc.
- Fig.3 shows a tube 1 in which flexible and a slender material is used and a flexible portion and taper portion are shortened.
- the balloon 4 is made of elastic cylindrical or spheroidal rubber latex, silicone rubber, urthane elastomer etc. in uniform thin membrane.
- the membrane of the balloon may be as much as about 250 p in thickness and its pressure resistant property can be improved compared with the one used in above flow guide wire, because the size of the balloon can be smaller before dilatation.
- a small hole through which normally fluid can not be passed may be provided at a part of the balloon 4 to prevent bursting of the balloon 4.
- the balloon 4 is attached so as to cover the flexible tip portion 10 of the tube 1, and the covered part is fixed by fastening tightly with fiber 8 of silk, nylon, polyester or urethane elastomer on the rubber and finished to have smooth and even surface by applying adhesive 9 to the surface. It is preferred to contain non-X ray transmission material at the tip of the balloon 4 as shown in the Figure, but it is not always necessary.
- the fluids to dilate the balloon 4 include liquids such as physiological saline or blood vessel contrast media or gases such as carbon dioxide, and they are introduced under pressure into the lumen 7 of the balloon via the'fluid transfer channel 6 and the fluid outlet hole 13 from an injector or a connector which is connected with the fluid inlet hole 5 in order to dilate the balloon 4.
- the tube 1 having the empty portion 2 which is opened through has even and smooth surface overall, its tip being finished slenderly to be flexible.
- the fluid inlet hole 5 is provided at the rear end.
- any of melt spinnable or extrusion modable plastic materials may be used, and polyamide, polyester, polyolefin or Teflon are preferably employed.
- the diameter of the empty portion 2 of the tube 1 is desirably larger, and it is necessary for even the structure from the taper portion 11 up to the flexible tip portion 10 which cannot be made larger in order to maintain tensile strength to be more than 0.15 mm.
- each portion of the tube 1 may depend on the age or body of the patient and severity of the illness and cannot be defined specifically. The normal typical sizes will be given below.
- the non-X ray transmission material 3 used in the present invention are metal wires having superior aniographic formation by X ray radiation such as gold, stainless steel or tungsten.
- the metal wires are processed taperingly not to choke the empty portion of the taper portion 11 but in other portions they have diameters of 20-80% of the inner diameter of the empty portion in the operational portion.
- a portion corresponding to flexible tip portion is formed by drawing it with heating, then the taper portion is formed by drawing suitably, and cut in desired length.
- the cut end of the flexible tip portion is slightly opened by heating.
- a balloon made of rubber latex which had separately prepared by coagulation method contained non-X ray transmission material 3' at the tip is covered, and if necessary, after ensuring fixation by applying adhesive, it is fastened tightly with fiber 8 as described above, and on the fiber the adhesive 9 is applied on the surface to finish it smoothly and the surface is finished to have gentle grade to complete the attachment of the balloon 4.
- non-X ray transmission material 3 processed taperingly is inserted and fixed at the rear end of the tube 1.
- non-X ray transmission material 3 wounded beforehand, is engaged with the empty portion 2, or adhesive is introduced into the empty portion 2 to fix the non-X ray transmission material 3 on the inside wall of the tube 1.
- the fluid inlet hole 5 is provided to the side of the tube by boring a hole in the side wall of the tube with a micro drill and if necessary, a connecting terminal such as a cap or a connector is provided to obtain the flow guide wire of the present invention.
- the expanded balloon of the flow guide wire of the present invention is introduced to peripheral blood vessel by way of blood flow to lead the guide wire. While an operator observes the image of the balloon by X ray radiation by a monitor, he can have its tip arrive at the target lesion of blood vessel more selectively.
- the thickness of the membrane of the balloon can be greater, and durability against expansion and shrinkage is improved.
- the air in the lumen of the balloon can be replaced with the liquid of the contrast medium for expansion of the balloon, and the confirmation of the balloon at the tip is very easy in use.
- the non-X ray transmission material 3 contained in the empty portion 2 of the tube 1 gives suitable hardness to the flow guide wire to obtain good operability, and the image represented through a monitor by X ray radiation is so fine that the position of the non-X ray transmission material 3' at the tip can be easily found.
- the balloon 4 at the tip is greatly dilated and movable freely according to blood flow, it is easily passed through winding blood vessels and can reach the lesion on peripheral blood vessel selectively.
- the balloon 4 is further dilated at the reached site, so that the tip of the flow guide wire is fixed at the wall of the blood vessel. Therefore, the transfer of the tip of the guide wire by the movement of the blood vessel and the insertion of the catheter is prevented, and the blood vessel is formed straight by pulling the guide wire to make the insertion of catheter easy. According to the present invention, better results are obtained for the diagnosis and treatment by catheterization.
- the operation can be more conveniently carried out than the use of prior flow guide wires when it is withdrawn from the catheter, because the tip portion is smaller than the operational portion.
- Fig.4 is an elevation view (a) and a cross section view (b) of an embodiment of the leak balloon catheter of the present invention.
- This comprises a balloon 4 which is a flexible elastic material and provided with a fine fluid outlet hole 14 at the tip, said balloon attaching to the tip of the tube 1 which has an empty portion 2 and is the body of the catheter.
- a stopper 15 which contacts directly with a fluid outlet hole 14 for exiting therapeutic liquid, and one end of fine fiber 16 is fixed at the stopper 15 while another a little loosened end of it is fixed in adhesive 9.through the engagement between the tube 1 and the balloon 4. All of these composes a valve mechanism which will be described below.
- the engagement portion of the balloon 4 and the tube 1 is fastened with fiber, and in order to avoid abnormal storage of blood, the knots and unevenness are finished smoothly with adhesive 9 and the difference between the rear end of the balloon and the catheter is finished to gentle grade.
- a small fluid inlet hole 5 for introducing therapeutic liquid is provided at the operational portion of the tube 1, and is interconnected with the empty portion 2 and the lumen of the balloon, and the empty portion 2 is utilized as a fluid transfer channel.
- Fig.5 shows an elevation view of an embodiment in which a pipe 91 comprising non-X ray transmission material (usually metal) is inserted between a fluid outlet hole 14 and a stopper 15.
- Fig.6 shows an embodiment in which the balloon 4 is attached to the tip of the tube by narrowing the outer diameter of the latter through drawing, the outer diameter of the attached balloon 4 being the same as that of the tube 1.
- Fig.7 is an elevation view of an embodiment in which a pipe 92 comprising non-X ray transmission material is employed for the connection between the tube 1 and the balloon 4.
- the tube 1 and the balloon 4 are capped each other from both ends of the pipe 92 comprising non-X ray transmission material along with their outer walls, and the outer circumferences of the tube 1 and the balloon 4 are fastened with yarn 18 to fix on the pipe 92.
- the knots of yarn and the unevenness of the connection are made smooth with adhesive 9.
- the yarn 16 connected with a valve mechanism is fixed between the pipe 92 and the balloon 4, and a stopper 15 engages with the tube 1.
- the balloon 4 attached at the tip of the tube 1 is an empty elastic body having a circular cross section which is oblongly cylindrical or spheroidal as well as flexible, and it has a sufficient strength not to be cut when dilated and introduced to the lesion by means of blood flow.
- a stopper 15 which contacts directly from the lumen of the balloon 4 with the pipe 91 comprising non-X ray transmission material and positioned at or in front of the fluid outlet hole 14 is a ball of which diameter is by about 50% larger than that of the outlet hole of fluid 15 and is smaller than that of the lumen of the balloon 4.
- the yarn 16 connecting them in fine and flexible so that the movement of the stopper 15 is free, and is loosened while the balloon 4 is not yet dilated, and its end is fixed between the tube 1 and the balloon 4, and has strength enough not to be cut or off under the pressure of the therapeutic liquid stream.
- the diameter of the yarn 16 is preferably about 10-40p.
- the fluid inlet hole 5 near the operational portion of the tube 1 is normally covered with a cap, and has a structure equipped with a connector or an injector.
- the material of the tube comprising a catheter is not particularly limited, but melt extrusion moldable tubes such as one of synthetic resins such as polyamides, polyesters, polyolefins and fluororesins are preferably used.
- melt extrusion moldable tubes such as one of synthetic resins such as polyamides, polyesters, polyolefins and fluororesins are preferably used.
- the catheter used for diagnosis and treatment of blood vessels within brain is required to be soft, silicone and polyurethane are suitably used.
- very flexible rubber latex, silicone rubber or urethane elastomer are preferably used.
- the balloon of rubber latex coated with silicone oil is preferred, because it prevents degradation or formation of thrombus in contacting with blood.
- the thinner elastic body for example, having the thickness of less than 300u preferably less than 200p is suitable.
- the diameter of the fine fluid outlet hole 14 is about 100-400u, since it becomes larger by dilatation even it is usually smaller.
- the therapeutic liquids used for dilatation of the balloon include physiological saline or contrast media, and they are extruded through the fluid outlet hole 14.
- each part of the leak balloon catheter of the present invention may be dependent on age of patient, physical constitution, severity of illness etc. and cannot be particularly defined.
- the normal typical sizes will be given as follows.
- the ball-like body used for a stopper 15 comprising a valve mechanism of the leak balloon catheter of the present invention may be of silicone or other synthetic resins, and stainless steel or steel, the latter two being preferred because of easy processing for boring a hole connected with yarn.
- silicone coating on the surface of the ball-like body is suitable because of close contacting.
- the fluid outlet hole 14 is not always necessary for the balloon.
- the operation should be careful because the therapeutic liquid remained in the lumen of the pipe is dried and clogged by withdrawing the air in the lumen of the catheter before use.
- the non-X ray transmission materials used herein include pipes of metals having superior angiographic formation by X ray radiation, typically gold or platinum, and metals being stable in therapeutic liquid are preferred.
- pipes used rigid synthetic resin as materials which are coated with a mixture of metal powder having angiographic formation ability by X ray radiation such as tungsten or tantalum etc. and adhesive, but in the absolute concentration of metal the above pipes are better.
- 0.2-0.6 mm of the diameter of hole of the pipe can be used without any difficulty of passing through therapeutic liquid.
- the plane of the pipe 91 contacting with the stopper 5 is made to be conical, it is more convenient because of greater contacting area with the ball-like body.
- the stopper 15 used for a valve mechanism normally contacts with the fluid outlet hole 14 or the pipe 91 comprising non-X ray transmission material from the lumen of the balloon 4, and when therapeutic liquid is injected into the lumen of the balloon 4 from the empty portion 2 which is a fluid transfer channel of the tube 1, it is at first pressed toward the fluid outlet hole 14 by the pressure of the liquid.
- the balloon begins to dilate because of no outlet, and finally it becomes dilated towards the direction in which the length of the balloon elongates.
- the yarn of the stopper under pressure elongates pressed with the fluid outlet hole 14 while the yarn 16 maintains loosen, but when the yarn 16 is stretched by the longation of the balloon 4, the stopper 15 is apart from the fluid outlet hole 4, and the fine hole opens and the leak of therapeutic liquid begins. Then even when the injection of therapeutic liquid stops, the leak of therapeutic liquid continues for some time under the pressure from autoshrinkage of the balloon 4. In time the lenthwise shrinkage of the balloon 4 begins.
- the stopper 15 since the stopper 15 receives the pressure of therapeutic liquid which continues to leak, the yarn 16 maintains stretched, and then the stopper 15 contacts with the fluid outlet hole 14 to choke up and stop the leak of therapeutic liquid.
- the form of the balloon is maintained as long as the injection pressure does not change.
- a hollow tube having 0.8mm of outer diameter and 0.4mm of inner diameter of hollow portion was prepared by conventional melt spinning through hollow spinneret, and was cut into a length of 1.5m. Then the tip portion of said tube was drawn by heating with steam to obtain soft and fine tip portion having 0.4mm of outer diameter and 0.25mm of inner diameter of hollow portion in length of about 3cm. The tip was formed slightly conically by heating, and was covered with a rubber latex tube which had be separately prepared by coagulation method and cut into the desired length, and then they were fastened tightly with polyurethane elastic yarn.
- the tip portion of the balloon fastened with polyurethane yarn and the exposed portion of the gold wire was made smooth and round with epoxy resin and unevenness was also made gentle grade, and the balloon and polyester tube were applied with silicone coating, and further a detachable connector for connecting with syringe was attached on the fluid inlet hole at the rear end to give the flow guide wire of the present invention.
- the wire was inserted into blood vessel from femoral artery by Seldinger's method, and reached lower mesenteric artery from abdominal aorta.
- the balloon was dilated to 4mm of diameter and made free by floating on blood flow. It floated on the blood flow to reach gastro-duodenal artery.
- the flow guide wire of the present invention was dilated into 4mm of diameter at the entrance of abdominal artery, and entered into inherent hepatic artery by floating in blood flow to reach the lesion of peripheral blood vessel of right hepatic artery.
- the balloon was further dilated and fixed on the inner wall of the blood vessel to introduce catheter without slipping off the tip of the guide wire. Consequently, it was possible that the catheter was inserted to the lesion and good therapeutical effect was obtained.
- Example 2 (Leak balloon catheter)
- a stopper 15 in which nylon yarn 6 having diameter of 0.03mm had fixed with adhesive on a stainless steel ball of 0.3mm of diameter with adhesive (Sankyo Pharmaceutical Co.: "ARON ⁇ A") was inserted into the lumen of a balloon 4 in which a fine hole had been bored with sharp-pointed piano wire-of-0.2mm of diameter at the tip of the rubber latex having 0.4mm of inner diameter, 0.15mm of thickness and 4mm of length.
- the balloon 4 having nylon yarn 4 of about 4mm in length was attached.
- Physiological saline was injected into the leak balloon catheter through a fluid inlet hole equipped with 25G injection syringe attached with a three way coke from an injection cylinder of volume of 2.5 ml, and the balloon was dilated at about 2.0 kg/cm 2 . When the valve was closed, the balloon maintained the form, and no leak from the fluid outlet hole was noticed.
- Example 3 Leak Balloon catheter
- a stopper 5 in which nylon yarn 6 of 0.04 mm of diameter had fixed with adhesive on a stainless steel ball of 0.3 mm of diameter and the surface had been coated with silicone (Toray Silicone: "SH781”) was inserted into the lumen of a rubber latex balloon 2 having 0.4 mm of inner diameter, 0.2 mm of thickness and 5 mm of length.
- silicone Toray Silicone: "SH781”
- a fine hole was bored with sharp-pointed piano wire of 0.2 mm of diameter, and within the lumen inserted was a gold pipe 91 having 0.2 mm of inner diameter and 0.5 mm of outer diameter of which one end of the lumen had been finished conically with very fine drill, the insertion being done from another unfinished end.
- the engaging portion and the gold pipe inserting portion were fixed on the circumference of the balloon by fastening with polyurethane yarn, and further with two-liquid type epoxy resin (Nagase-Ciba: "ARALDITE” "HARDNER”) to finish smoothly, and unevenness between the balloon and the catheter was made gentle grade.
- the balloon catheter of the present invention inserted into femoral artery by Seldinger's method, the balloon was not dilated from femoral artery to abdominal artery, but contrast medium ("Andiographin") was injected under pressure through an injection syringe at the fluid inlet hole 5 from an injection cylinder filled with the medium through abdominal artery to hepatic arteries to dilate the balloon which floated in blood flow. Adding slight pressure to dilate the blood vessel itself, it easily reached left hepatic artery and the injection of therapeutic liquid (antitumor agent) could be done.
- the gold pipe 91 at the tip portion could be visually traced by an X ray radiation monitor, and when the leak balloon catheter was withdrawn, it could be clean only by wiping with gauze and no blood was noted.
- the leak balloon catheter of the present invention can float on blood flow and move freely by adjusting the size of the balloon depending on the state of the blood vessel of the patient after the insertion into the blood vessel.
- the guiding ability of the balloon is remarkably improved, and the balloon can reach the peripheral part without creaping into or injuring inner wall of blood vessel even at the branched part of blood vessel and would blood vessel. Therefore, the burden of patients is not only relieved, but the concern of the operator is remarkably lightened.
- a contrast medium is used for the dilatation of the balloon, observation by monitor is definite, and therapeutic liquid is readily replaced and injected when it reaches lesion and the therapeutic liquid is injected under pressure.
- Using a pipe of non-X ray transmission metal at the tip even at the injection of therapeutic liquid, the case in which the tip of the catheter is transferred to another blood vessel can be easily found by the movement of the blood vessel and the operation can be amended.
- the infusion of therapeutic liquid can be carried out maintaining the dilated tip balloon, it is possible to effect the infusion under limitation or choking up of blood flow.
- F igs.1-3 show the guiding microtube of the present invention suitable for the use as flow guide wire.
- Fig.1(a) is an elevation cross sectional view of the fundamental structure thereof
- Fig.1(b) is a cross sectional view of part A-A' in Fig.1(a)
- Fig. 1(c) is a cross sectional view of part B-B' in Fig. 1(a)
- Fig.2 is an elevation cross sectional view of a structure wherein non-X ray transmission material 3 t is contained in the tip of the lumen of a balloon
- Fig.3 is an elevation cross sectional view of a structure wherein flexible and slender material is used for a synthetic resin tube 1 and the flexible portion and taper portion are shortened.
- Figs.4-7 show a guiding microtube of the present invention suitable for the use as leak balloon catheter.
- Fig.4(a) is an elevation view of the fundamental structure thereof
- Fig.4(b) is a cross sectional view of part A-A' in Fig: 1 (a)
- Figs.5, 6 and 7 are elevation views of the tip portions of other embodiments.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60002131A JPS61162956A (ja) | 1985-01-11 | 1985-01-11 | リ−クバル−ンカテ−テル |
JP2131/85 | 1985-01-11 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0208787A1 true EP0208787A1 (fr) | 1987-01-21 |
EP0208787A4 EP0208787A4 (fr) | 1988-02-17 |
EP0208787B1 EP0208787B1 (fr) | 1992-08-26 |
Family
ID=11520781
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP86900633A Expired - Lifetime EP0208787B1 (fr) | 1985-01-11 | 1986-01-10 | Micro-tube medical de guidage |
Country Status (6)
Country | Link |
---|---|
US (1) | US4909796A (fr) |
EP (1) | EP0208787B1 (fr) |
JP (1) | JPS61162956A (fr) |
KR (1) | KR930010960B1 (fr) |
DE (1) | DE3686527T2 (fr) |
WO (1) | WO1986003979A1 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0278937A2 (fr) * | 1987-02-13 | 1988-08-17 | Stig Bengmark | Méthode pour positioner un tube dans l'intestin grêle |
WO1992014508A1 (fr) * | 1991-02-15 | 1992-09-03 | Mallinckrodt Medical, Inc. | Fil de guidage stable a la torsion |
EP0766977A1 (fr) * | 1995-10-06 | 1997-04-09 | Olympus Optical Co., Ltd. | Cathéter |
WO1997037714A1 (fr) * | 1996-04-05 | 1997-10-16 | Medtronic, Inc. | Catheter a ballonnet a gonflage et regulation automatiques |
US5730733A (en) * | 1995-06-01 | 1998-03-24 | Scimed Life Systems, Inc. | Flow assisted catheter |
AU704027B2 (en) * | 1995-11-08 | 1999-04-15 | Shell Internationale Research Maatschappij B.V. | Catalyst activation and rejuvenation process |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5860938A (en) * | 1996-03-07 | 1999-01-19 | Scimed Life Systems, Inc. | Medical pressure sensing guide wire |
US5964714A (en) * | 1996-03-07 | 1999-10-12 | Scimed Life Systems, Inc. | Pressure sensing guide wire |
US5899892A (en) * | 1996-05-31 | 1999-05-04 | Scimed Life Systems, Inc. | Catheter having distal fiber braid |
US6193705B1 (en) | 1998-10-28 | 2001-02-27 | Scimed Life Systems, Inc. | Flow assisted catheter |
NZ519810A (en) * | 1999-12-27 | 2004-05-28 | Alza Corp | Osmotic beneficial agent delivery system |
US6997713B2 (en) * | 2003-09-24 | 2006-02-14 | Levatino Samuel R | Microtubes for surgery and dentistry |
US20050197683A1 (en) * | 2003-09-24 | 2005-09-08 | Levatino Samuel R. | Microtubes for surgery and dentistry |
US20040107283A1 (en) * | 2003-10-06 | 2004-06-03 | Trilibis Inc. | System and method for the aggregation and matching of personal information |
US20070073160A1 (en) | 2005-09-13 | 2007-03-29 | Children's Medical Center Corporation | Light-guided transluminal catheter |
US8954134B2 (en) * | 2005-09-13 | 2015-02-10 | Children's Medical Center Corporation | Light-guided transluminal catheter |
DE102006024095A1 (de) * | 2006-05-17 | 2007-12-06 | Epflex Feinwerktechnik Gmbh | Druckanschlussvorrichtung für eine Führungsdrahteinheit |
EP2279766B1 (fr) | 2009-07-31 | 2014-06-18 | Abbott Laboratories Vascular Enterprises Limited | Tubes non métalliques pour dispositifs médicaux |
JP2017125224A (ja) * | 2016-01-12 | 2017-07-20 | 仲山貴金属鍍金株式会社 | 金属管及びその製造方法 |
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US4024873A (en) * | 1976-05-24 | 1977-05-24 | Becton, Dickinson And Company | Balloon catheter assembly |
US4029104A (en) * | 1976-03-08 | 1977-06-14 | Kerber Charles W | Calibrated leak balloon micro-catheter |
FR2465488A1 (fr) * | 1976-04-29 | 1981-03-27 | Pevsner Paul | Catheter a ballonnet de petites dimensions utilisable pour effectuer des perfusions dans les vaisseaux sanguins |
EP0042703A1 (fr) * | 1980-06-23 | 1981-12-30 | Toray Monofilament Company Limited | Cathéter médical endo-veineux du type auto-guidé |
US4341218A (en) * | 1978-05-30 | 1982-07-27 | University Of California | Detachable balloon catheter |
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US4346712A (en) * | 1979-04-06 | 1982-08-31 | Kuraray Company, Ltd. | Releasable balloon catheter |
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US4646742A (en) * | 1986-01-27 | 1987-03-03 | Angiomedics Incorporated | Angioplasty catheter assembly |
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- 1985-01-11 JP JP60002131A patent/JPS61162956A/ja active Granted
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1986
- 1986-01-10 DE DE8686900633T patent/DE3686527T2/de not_active Expired - Lifetime
- 1986-01-10 KR KR1019860700632A patent/KR930010960B1/ko not_active IP Right Cessation
- 1986-01-10 EP EP86900633A patent/EP0208787B1/fr not_active Expired - Lifetime
- 1986-01-10 WO PCT/JP1986/000007 patent/WO1986003979A1/fr active IP Right Grant
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1989
- 1989-05-09 US US07/349,912 patent/US4909796A/en not_active Expired - Lifetime
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US4029104A (en) * | 1976-03-08 | 1977-06-14 | Kerber Charles W | Calibrated leak balloon micro-catheter |
FR2465488A1 (fr) * | 1976-04-29 | 1981-03-27 | Pevsner Paul | Catheter a ballonnet de petites dimensions utilisable pour effectuer des perfusions dans les vaisseaux sanguins |
US4024873A (en) * | 1976-05-24 | 1977-05-24 | Becton, Dickinson And Company | Balloon catheter assembly |
US4024873B1 (fr) * | 1976-05-24 | 1984-09-18 | ||
US4341218A (en) * | 1978-05-30 | 1982-07-27 | University Of California | Detachable balloon catheter |
EP0042703A1 (fr) * | 1980-06-23 | 1981-12-30 | Toray Monofilament Company Limited | Cathéter médical endo-veineux du type auto-guidé |
Non-Patent Citations (1)
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Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0278937A2 (fr) * | 1987-02-13 | 1988-08-17 | Stig Bengmark | Méthode pour positioner un tube dans l'intestin grêle |
EP0278937A3 (en) * | 1987-02-13 | 1990-07-25 | Stig Bengmark | Method and tube equipment for supplying fluid to a space and draining said space |
WO1992014508A1 (fr) * | 1991-02-15 | 1992-09-03 | Mallinckrodt Medical, Inc. | Fil de guidage stable a la torsion |
US5730733A (en) * | 1995-06-01 | 1998-03-24 | Scimed Life Systems, Inc. | Flow assisted catheter |
EP0766977A1 (fr) * | 1995-10-06 | 1997-04-09 | Olympus Optical Co., Ltd. | Cathéter |
US5800411A (en) * | 1995-10-06 | 1998-09-01 | Olympus Optical Co., Ltd. | Catheter |
AU704027B2 (en) * | 1995-11-08 | 1999-04-15 | Shell Internationale Research Maatschappij B.V. | Catalyst activation and rejuvenation process |
US6458096B1 (en) | 1996-04-01 | 2002-10-01 | Medtronic, Inc. | Catheter with autoinflating, autoregulating balloon |
US6749583B2 (en) | 1996-04-01 | 2004-06-15 | Medtronic, Inc. | Catheter with autoinflating, autoregulating balloon |
WO1997037714A1 (fr) * | 1996-04-05 | 1997-10-16 | Medtronic, Inc. | Catheter a ballonnet a gonflage et regulation automatiques |
EP1118348A3 (fr) * | 1996-04-05 | 2001-09-05 | Medtronic, Inc. | Cathéter à ballonnet à gonflage et régulation automatiques |
Also Published As
Publication number | Publication date |
---|---|
DE3686527T2 (de) | 1993-03-25 |
EP0208787B1 (fr) | 1992-08-26 |
US4909796A (en) | 1990-03-20 |
KR870700015A (ko) | 1987-02-28 |
JPS61162956A (ja) | 1986-07-23 |
KR930010960B1 (ko) | 1993-11-18 |
JPH0434416B2 (fr) | 1992-06-05 |
WO1986003979A1 (fr) | 1986-07-17 |
EP0208787A4 (fr) | 1988-02-17 |
DE3686527D1 (de) | 1992-10-01 |
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