EP0056609A3 - Separation tube for separating by centrifugation - Google Patents

Separation tube for separating by centrifugation Download PDF

Info

Publication number
EP0056609A3
EP0056609A3 EP82100181A EP82100181A EP0056609A3 EP 0056609 A3 EP0056609 A3 EP 0056609A3 EP 82100181 A EP82100181 A EP 82100181A EP 82100181 A EP82100181 A EP 82100181A EP 0056609 A3 EP0056609 A3 EP 0056609A3
Authority
EP
European Patent Office
Prior art keywords
separating
separating member
components
tube
centrifugation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP82100181A
Other languages
German (de)
Other versions
EP0056609A2 (en
EP0056609B1 (en
Inventor
Uwe Werner Dr. Ballies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AT82100181T priority Critical patent/ATE6993T1/en
Publication of EP0056609A2 publication Critical patent/EP0056609A2/en
Publication of EP0056609A3 publication Critical patent/EP0056609A3/en
Application granted granted Critical
Publication of EP0056609B1 publication Critical patent/EP0056609B1/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B01L3/50215—Test tubes specially adapted for centrifugation purposes using a float to separate phases

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Centrifugal Separators (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

A separating tube (2) preferably made from a plastics material for centrifugal separation of a liquid containing at least two components and preferably blood is provided, in which an asymmetrically shaped separating member (6) serves to separate the two components. The separating member (6) has a specific gravity between that of the two components to be separated. As a result of the asymmetrical shape, the center of gravity (S) of separating member (6) is eccentrically positioned with respect to axis (M) of separating tube (2), so that the separating member (6) is rotated or tilted during centrifuging. At least one gap (f) is formed through which one of the two components reaches the top of separating member (6). At the end of the centrifuging process, the bouyancy of the heavier component rotates separating member (6) back into its original position in which it seals off separating tube (2). FIG. 4 is intended for publication with the summary.
EP82100181A 1981-01-21 1982-01-13 Separation tube for separating by centrifugation Expired EP0056609B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT82100181T ATE6993T1 (en) 1981-01-21 1982-01-13 SEPARATOR TUBE FOR CENTRIFUGAL SEPARATION.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3101733A DE3101733C2 (en) 1981-01-21 1981-01-21 Separating element in a separating tube for centrifugal separation
DE3101733 1981-01-21

Publications (3)

Publication Number Publication Date
EP0056609A2 EP0056609A2 (en) 1982-07-28
EP0056609A3 true EP0056609A3 (en) 1982-12-08
EP0056609B1 EP0056609B1 (en) 1984-04-11

Family

ID=6122999

Family Applications (1)

Application Number Title Priority Date Filing Date
EP82100181A Expired EP0056609B1 (en) 1981-01-21 1982-01-13 Separation tube for separating by centrifugation

Country Status (4)

Country Link
US (1) US4364832A (en)
EP (1) EP0056609B1 (en)
AT (1) ATE6993T1 (en)
DE (2) DE3101733C2 (en)

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DE8910591U1 (en) * 1989-09-05 1989-12-21 Walter Sarstedt Geräte und Verbrauchsmaterial für Medizin und Wissenschaft, 5223 Nümbrecht Blood serum collection device
WO1994009836A2 (en) * 1992-11-03 1994-05-11 Chronomed, Inc. Methods and procedures for preparing red blood fractions
DE4332189A1 (en) 1993-09-22 1995-03-23 Braun Melsungen Ag Blood collection device
US5741423A (en) * 1994-08-23 1998-04-21 Bates; John Liquid-liquid extraction
US5575778A (en) * 1994-09-21 1996-11-19 B. Braun Melsungen Ag Blood-taking device
US6280400B1 (en) 1998-12-05 2001-08-28 Becton Dickinson And Company Device and method for separating component of a liquid sample
US6406671B1 (en) 1998-12-05 2002-06-18 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US6497325B1 (en) 1998-12-05 2002-12-24 Becton Dickinson And Company Device for separating components of a fluid sample
US6516953B1 (en) 1998-12-05 2003-02-11 Becton, Dickinson And Company Device for separating components of a fluid sample
US6803022B2 (en) 1999-12-06 2004-10-12 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US6471069B2 (en) 1999-12-03 2002-10-29 Becton Dickinson And Company Device for separating components of a fluid sample
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
US6537503B1 (en) 1999-12-03 2003-03-25 Becton Dickinson And Company Device and method for separating components of a fluid sample
US6409528B1 (en) 1999-12-06 2002-06-25 Becton, Dickinson And Company Device and method for collecting, preparation and stabilizing a sample
CA2407346C (en) * 2000-04-28 2009-09-01 Harvest Technologies Corporation Blood components separator disk
US6465256B1 (en) 2000-08-26 2002-10-15 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US7374678B2 (en) 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
AU2003249642A1 (en) 2002-05-24 2003-12-12 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
ATE522273T1 (en) * 2003-05-19 2011-09-15 Harvest Technologies Corp METHOD AND DEVICE FOR SEPARATING FLUID COMPONENTS
EP1696785A4 (en) * 2003-12-09 2011-04-13 Lipose Corp Fat collection and preparation system and method
US20050124073A1 (en) * 2003-12-09 2005-06-09 Entire Interest Fat collection and preparation system and method
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
WO2006086201A2 (en) 2005-02-07 2006-08-17 Hanuman Llc Platelet rich plasma concentrate apparatus and method
EP2666494B1 (en) 2005-02-07 2018-01-17 Hanuman LLC Platelet rich plasma concentrate apparatus and method
US20070003449A1 (en) * 2005-06-10 2007-01-04 Mehdi Hatamian Valve for facilitating and maintaining fluid separation
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
JP5479319B2 (en) 2007-04-12 2014-04-23 バイオメット・バイオロジックス・リミテッド・ライアビリティ・カンパニー Buoy suspension fractionation system
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
EP2259774B1 (en) 2008-02-27 2012-12-12 Biomet Biologics, LLC Methods and compositions for delivering interleukin-1 receptor antagonist
US8337711B2 (en) 2008-02-29 2012-12-25 Biomet Biologics, Llc System and process for separating a material
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
EP2326421B1 (en) 2008-07-21 2012-06-20 Becton, Dickinson and Company Density phase separation device
CA2731155C (en) 2008-07-21 2013-09-24 Becton, Dickinson And Company Density phase separation device
CA2731156C (en) 2008-07-21 2013-09-24 Becton, Dickinson And Company Density phase separation device
US8177072B2 (en) 2008-12-04 2012-05-15 Thermogenesis Corp. Apparatus and method for separating and isolating components of a biological fluid
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
SG176028A1 (en) 2009-05-15 2011-12-29 Becton Dickinson Co Density phase separation device
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US20130116103A1 (en) * 2011-11-08 2013-05-09 Jonathan Erik Lundt Systems and methods for separating target materials in a suspension
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
US20160136639A1 (en) * 2014-11-13 2016-05-19 Becton, Dickinson And Company Mechanical Separator for a Biological Fluid
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001122A (en) * 1973-08-22 1977-01-04 Telan Corporation Method and device for separating blood components
DE2711731A1 (en) * 1976-05-06 1977-11-17 Sherwood Medical Ind Inc FLUID COLLECTION DEVICE
DE2734720A1 (en) * 1977-03-16 1979-02-15 Ballies Uwe Tube for sepn. by centrifugation - is made of synthetic material and contains moving cylindrical separator preventing subsequent remixing

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997442A (en) * 1974-03-18 1976-12-14 Corning Glass Works Method of separating and partitioning differing density phases of a multiphase fluid
US3981804A (en) * 1975-06-25 1976-09-21 Corning Glass Works Apparatus for separating multiphase fluids
AT381466B (en) * 1977-03-16 1986-10-27 Ballies Uwe SEPARATING TUBES FOR CENTRIFUGAL SEPARATION
DE2711336C2 (en) * 1977-03-16 1985-05-02 Uwe Werner Dr.Med. 2300 Kiel Ballies Separation tubes for centrifugal separation
US4147628A (en) * 1978-01-23 1979-04-03 Becton, Dickinson And Company Blood partitioning method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001122A (en) * 1973-08-22 1977-01-04 Telan Corporation Method and device for separating blood components
DE2711731A1 (en) * 1976-05-06 1977-11-17 Sherwood Medical Ind Inc FLUID COLLECTION DEVICE
DE2734720A1 (en) * 1977-03-16 1979-02-15 Ballies Uwe Tube for sepn. by centrifugation - is made of synthetic material and contains moving cylindrical separator preventing subsequent remixing

Also Published As

Publication number Publication date
US4364832A (en) 1982-12-21
DE3101733A1 (en) 1982-08-05
DE3260096D1 (en) 1984-05-17
ATE6993T1 (en) 1984-04-15
EP0056609A2 (en) 1982-07-28
EP0056609B1 (en) 1984-04-11
DE3101733C2 (en) 1982-10-14

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