EP0032098B1 - Dispositif de prélèvement et de distribution de volumes réglables de liquides, à affichage numérique - Google Patents

Dispositif de prélèvement et de distribution de volumes réglables de liquides, à affichage numérique Download PDF

Info

Publication number
EP0032098B1
EP0032098B1 EP80401875A EP80401875A EP0032098B1 EP 0032098 B1 EP0032098 B1 EP 0032098B1 EP 80401875 A EP80401875 A EP 80401875A EP 80401875 A EP80401875 A EP 80401875A EP 0032098 B1 EP0032098 B1 EP 0032098B1
Authority
EP
European Patent Office
Prior art keywords
sleeve
control rod
rotation
cover
casing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
EP80401875A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0032098A1 (fr
Inventor
Eric Marteau D'autry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AT80401875T priority Critical patent/ATE3138T1/de
Publication of EP0032098A1 publication Critical patent/EP0032098A1/fr
Application granted granted Critical
Publication of EP0032098B1 publication Critical patent/EP0032098B1/fr
Expired legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/022—Capillary pipettes, i.e. having very small bore
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/026—Drum counters

Definitions

  • the present invention relates to a device for collecting and distributing adjustable volumes of liquid samples, with digital display.
  • the invention therefore applies equally well to micro-pipettes equipped at their lower end with sampling cones or to displacement pipettes; positive, than to all other sampling and distribution devices such as dilutors for example.
  • the devices of this kind of the prior art have the drawback of comprising boxes that are too long. This excessive axial dimension of the boxes was made necessary by the very design of the adjustment and display mechanisms in accordance with the prior art, for example illustrated by French patent application FR-A-2 203 680. It should be noted that such a drawback becomes particularly troublesome in the case of handling so-called "positive displacement" pipettes, ie comprising in addition at their lower part a calibrated capillary tube of a certain length in which a piston moves in leaktight manner.
  • the present invention therefore aims to completely modify the design of such adjustment and display mechanisms, so as to be able to limit their axial size.
  • the sheath is able to penetrate substantially completely into the housing.
  • the diameter of the internal opening of the sleeve is dimensioned so as to allow the penetration of the sheath into the sleeve.
  • the pipette shown by way of nonlimiting example in FIG. 1 is of the so-called "positive displacement" type.
  • a pipette conventionally comprises an upper housing 10 integral with a substantially tubular lower body 12 fitted at its lower end, in a removable manner, with a calibrated capillary tube 24 in which a piston 14 controlled in its movement moves in sealed manner. displacement by a control rod 20.
  • the capillary tube 24 is preferably constituted by a glass tube calibrated in diameter but not in length.
  • the piston 14 has at least one sealing zone.
  • This piston can for example advantageously be produced in the form of a stainless steel wire having, in the case of rods of small diameters, a coating for example of Teflon.
  • the stop for limiting the upward stroke of the piston is none other than the stop for limiting the stroke of the pinching member of the piston 14.
  • This upper stop is of course adjustable in vertical position, so that the useful stroke of the sampling and distribution piston can be modified by adjusting the position of this upper stop.
  • the lower stroke limit stop remains fixed.
  • Such devices usually include an upper housing 10 secured to a substantially cylindrical lower body 12 in which a piston 14 which alternately moves is elastically urged to come into contact with an adjustable upper stop for limiting the stroke of the piston.
  • a piston 14 which alternately moves is elastically urged to come into contact with an adjustable upper stop for limiting the stroke of the piston.
  • the clamping member 16 which is resiliently urged upwards thanks to the spring 18, and which is controlled in its movement simultaneously with the piston 14 by a control rod 20 passing through the housing 10.
  • the upper end of the rod 20 is provided with a push button 22.
  • the adjustment and display mechanism proper comprises a sleeve 26 threaded over its entire outer part, which thus enables it to cooperate by screwing with a corresponding thread made directly on the inner wall of the housing 10.
  • the sleeve 26 is able to penetrate, substantially completely, in the cavity 30 of the housing 10. It will be observed that, in the embodiment described, the lower part of the sleeve 26 constituting the variable stop in the present position a radial peripheral projection 32 which is intended to limit the screwing depth of the sleeve 26 inside the cavity 30 of the housing 10.
  • the sleeve 26 is shown in a position close to its upper limit position.
  • the mechanism according to the invention further comprises a prismatic control rod 20 which passes entirely through the sheath 26 and whose particular profile ensures the rotational attachment of the rod 20 with the sheath 26 while, however, allowing free relative winding of the rod 20 with respect to the sleeve 26.
  • the control rod 20 has a hexagonal section, and the threaded sleeve 26 has a through quality of homologous section. It is perfectly clear that the particular section of the control rod 20 can affect any other rectilinear or curvilinear polygonal shape or other more irregular shapes.
  • the important characteristic of the rod-sleeve assembly is the close cooperation between these two members, so that a rotation of the control rod 20 always causes rotation of the sleeve 26 while allowing their relative free sliding.
  • the mechanism according to the invention further comprises a sleeve 34 which is mounted to rotate freely in the upper part of the housing 10, coaxial with the sleeve 26 and the control rod 20. It will now be noted that, during the mounting of the pipette, after having screwed the sheath 26 inside the cavity 30 of the housing 10, the sleeve 34 is placed in the upper part of the housing 10 and, at this time, the sleeve 34 remains completely independent of any rotation rod 20 and / or sleeve 26.
  • the diameter 36 of the internal orifice of the sleeve 34 must be dimensioned so as to allow penetration of the sheath 26 inside said sleeve 34.
  • Such a characteristic precisely allows reduce the length of the cavity 30 of the housing 10 intended to receive the entire adjustment and display mechanism while allowing a large useful adjustment stroke.
  • the sleeve 34 is furthermore removably fitted with a means for securing in rotation with the control rod 20.
  • this securing means consists of a part of revolution 38 having an orifice interior of formed homologous to the exterior profile of the control rod 20, so as to be able to rotate with the latter.
  • the lower end of the joining piece 38 ends in a conical part 40 intended to allow it to be wedged in the upper part of the sleeve 34.
  • a coincidence therefore allows the sleeve 34 and the control rod to be joined in rotation. 20.
  • This particular provision will make it possible in particular to adjust the pipette to zero, for example during assembly at the factory.
  • the orifice in the upper part of the housing 10 is advantageously closed by a snap-on cover 42 simultaneously ensuring that the sleeve 34 and the various volume indicator drums described in more detail are held in place below.
  • the sleeve 34 shown in the accompanying drawings has at its lower part a radial projection 44 intended to cooperate with a homologous recess 46 formed on the inner wall of the housing 10.
  • the joining piece 38 has, in the vicinity of its upper part, a crown 50 provided with a peripheral groove intended to receive a friction ring 52 which, by cooperation with the homologous part of the cover 42, ensures the immobilization of the adjustment mechanism in the position chosen by the user.
  • a friction ring 52 which, by cooperation with the homologous part of the cover 42, ensures the immobilization of the adjustment mechanism in the position chosen by the user.
  • a braking ring 52 will be made of an elastically deformable flexible material, resistant to wear and tearing.
  • a braking ring made of a material chosen from fluorocarbon resins, polychloroprene and preferably polyurethanes.
  • the upper part of the attachment piece 38 comprises a sort of crown provided with a peripheral groove 54, a recess or even a projection intended to materialize a gripping area, to allow the extraction of said attachment piece 38 outside the sleeve 34. Since this dismantling operation of the adjustment and display mechanism of the pipette should in principle only be carried out in the factory, these gripping zones will be very difficult, if not at all, accessible from outside the housing 10, and will preferably require the use of a special shaped key intended to allow the extraction of this part only by qualified personnel.
  • the mechanism for ensuring the display of the sample volume chosen by the operator also includes a plurality of volume indicator drums.
  • These volume indicator drums for example the drum of the units 56, the tens drum 58 and the hundreds drum 60, are mounted around said sleeve 34 so as to stack them on top of each other.
  • the radial projection 44 previously described also makes it possible to avoid sliding downwards and placing the first drum 56 indicating the units in exact position.
  • this first drum of the units must be integral in rotation with the sleeve 34. This attachment can be obtained, for example by wedging, by gluing or by any other suitable means.
  • the other drums (tens 58 and hundreds 60) remain completely free to rotate around the sleeve 34.
  • drums are however obviously coupled with drive means capable of controlling their relative displacement in dependence on the movement of the sleeve 34 , the movement of the sleeve 26 and the movement of the control rod 20, which are all integral in rotation as seen previously when the pipette is fully assembled.
  • the drums respectively indicate the volume settings in units, tens and hundreds of microliters. It is perfectly possible to provide more or less drums, graduated in any desired unit.
  • the movement of the drums relative to each other is carried out in a conventional manner. For a complete rotation of the drum 56 of the units, only a pair of teeth drives a rock 62 mounted on a shaft 64, which penetrates into the snap-on cover 42. Rock 62 drives continuous gears on the tens drum 58 to move it d 'a tenth of a turn. Similarly, a complete rotation of the tens drum 58 causes a unitary movement of the hundreds drum 60 by the play of a simple pair of gear teeth, an additional rock 66 and a continuous gear on the hundreds drum. 60.
  • the casing 10 of the pipette conventionally comprises a transparent window 68 allowing the reading of the indicator drums.
  • the push button 22 is produced in two independent parts. Only the lower part 70 drives the control rod 20 in rotation. This solidarity in rotation of the lower part 70 of the push button 22 can be obtained by any suitable means, for example by giving the orifice passing through this lower part 70 of the button 22 a shape homologous to the external profile of the control rod 20.
  • the upper part 72 of the push button remains completely free to rotate both relative to the control rod 20 relative to the lower part 70 of the push button 22.
  • Such an arrangement has the advantage of avoiding any risk of the pipette being adjusted during use of the pipette. The operator thus exerts pressure on the upper part 72 and only on this upper part of the button 22 using his thumb.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Treatment Of Fiber Materials (AREA)
EP80401875A 1980-01-04 1980-12-29 Dispositif de prélèvement et de distribution de volumes réglables de liquides, à affichage numérique Expired EP0032098B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT80401875T ATE3138T1 (de) 1980-01-04 1980-12-29 Vorrichtung zum entnehmen und wiederabgeben waehlbarer fluessigkeitsmengen mit einer numerischen anzeige.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8000130A FR2473124A1 (fr) 1980-01-04 1980-01-04 Dispositif de prelevement et de distribution de volumes reglables de liquides, a affichage numerique
FR8000130 1980-01-04

Publications (2)

Publication Number Publication Date
EP0032098A1 EP0032098A1 (fr) 1981-07-15
EP0032098B1 true EP0032098B1 (fr) 1983-04-27

Family

ID=9237217

Family Applications (1)

Application Number Title Priority Date Filing Date
EP80401875A Expired EP0032098B1 (fr) 1980-01-04 1980-12-29 Dispositif de prélèvement et de distribution de volumes réglables de liquides, à affichage numérique

Country Status (6)

Country Link
US (1) US4362063A (enrdf_load_stackoverflow)
EP (1) EP0032098B1 (enrdf_load_stackoverflow)
JP (1) JPS5716332A (enrdf_load_stackoverflow)
AT (1) ATE3138T1 (enrdf_load_stackoverflow)
DE (1) DE3062907D1 (enrdf_load_stackoverflow)
FR (1) FR2473124A1 (enrdf_load_stackoverflow)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515339A1 (fr) * 1981-10-28 1983-04-29 Marteau D Autry Eric Pipette de precision a deplacement positif
US4501163A (en) * 1983-08-30 1985-02-26 Macdermott Bruce R Adjustable micro-dispensing liquid pipet
US4567780A (en) * 1984-03-12 1986-02-04 American Hospital Supply Corporation Hand-held pipette with disposable capillary
FI844320A7 (fi) * 1984-11-02 1986-05-03 Labsystems Oy Utspaedningsdoseringsanordning.
CH671526A5 (enrdf_load_stackoverflow) * 1985-12-17 1989-09-15 Hamilton Bonaduz Ag
FR2607407B1 (fr) * 1986-11-27 1991-08-02 Marteau D Autry Eric Procede et dispositif de calibrage d'une pipette de prelevement et de dosage
US5104625A (en) * 1989-10-04 1992-04-14 Drummond Scientific Company Pipetter device
US5104624A (en) * 1989-10-20 1992-04-14 Costar Corporation Pipetter
US5192511A (en) * 1991-05-31 1993-03-09 Tri-Continent Scientific, Inc. Pipette tip and piston
US5320810A (en) * 1992-05-13 1994-06-14 Integrated Instrument Services, Inc. Pipette with an axially stationary volume adjusting wheel
EP0689622B1 (en) * 1993-03-16 1997-07-09 W.L. Gore & Associates, Inc. Composite fiber of commingled fiberglass and polytetrafluoroethylene and method of producing same
US6814936B1 (en) 1999-07-01 2004-11-09 Goran Enhorning Pipette assembly having a small volume disposable tip
KR101587785B1 (ko) * 2014-05-20 2016-01-22 (주)연우 액체용기용 정량 토출장치
CN106459865B (zh) 2014-06-17 2019-01-08 雅马哈发动机株式会社 缸型尖头安装头、使用该缸型尖头安装头的头装置以及移动装置
EP3917671B1 (en) 2019-01-28 2024-02-21 Formulatrix International Holding Ltd Positive displacement pipette tip for motorized control automation or instrument system
CN114705500B (zh) * 2022-03-23 2022-10-25 瑞安市人民医院(瑞安市人民医院医疗服务集团瑞安市妇幼保健院瑞安市红十字医院) 一种高效精确的药学用微量药剂取样设备

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2203680A1 (enrdf_load_stackoverflow) * 1972-10-24 1974-05-17 Gilson Warren
FR2427134A1 (fr) * 1978-06-02 1979-12-28 Suovaniemi Finnpipette Pipette de volume reglable, a manchon d'arret filete exterieurement

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3327904A (en) * 1966-01-11 1967-06-27 Greiner Scient Corp Liquid dispensing devices
GB1403790A (en) * 1972-10-19 1975-08-28 British Insulated Callenders Wire drawing machinery
US4250755A (en) * 1979-10-22 1981-02-17 Drummond Scientific Co. Pipette

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2203680A1 (enrdf_load_stackoverflow) * 1972-10-24 1974-05-17 Gilson Warren
FR2427134A1 (fr) * 1978-06-02 1979-12-28 Suovaniemi Finnpipette Pipette de volume reglable, a manchon d'arret filete exterieurement

Also Published As

Publication number Publication date
DE3062907D1 (en) 1983-06-01
EP0032098A1 (fr) 1981-07-15
FR2473124B1 (enrdf_load_stackoverflow) 1982-06-25
JPS5716332A (en) 1982-01-27
FR2473124A1 (fr) 1981-07-10
US4362063A (en) 1982-12-07
ATE3138T1 (de) 1983-05-15
JPS6366576B2 (enrdf_load_stackoverflow) 1988-12-21

Similar Documents

Publication Publication Date Title
EP0032098B1 (fr) Dispositif de prélèvement et de distribution de volumes réglables de liquides, à affichage numérique
EP0591038B1 (fr) Perfectionnement à une pipette de prélèvement et de distribution de volumes réglables de liquides
EP0014120B1 (fr) Pipette à déplacement positif
EP0074883B1 (fr) Mécanisme de translation rectiligne à poulies et courroies
EP0078724B1 (fr) Pipette de précision à déplacement positif
FR2727037A1 (fr) Centrifugeuse a rotor demontable et a dispositif de blocage axial du rotor sur l'arbre d'entrainement
WO1997019642A1 (fr) Dispositif pour le prelevement de muqueuses uterines
EP0032469A1 (fr) Pipette à déplacement positif perfectionnée
EP0272963A1 (fr) Pipette de prélèvement et de dosage; procédé et dispositif pour son calibrage
FR2464420A1 (fr) Robinet de dosage a commande magnetique
EP0192544B1 (fr) Serrure perfectionnée à cylindre, à combinaison sans clé et outil de changement de combinaison
FR2639260A1 (fr) Baton applicateur de produit pateux
EP3749456B1 (fr) Dispositif de verrouillage d'une vis de réglage de volume pour un système de pipetage
CH643145A5 (fr) Dispositif pour prelever un volume predetermine et reglable de liquide dans un recipient.
WO2024236239A1 (fr) Connexion amovible d'une sonde ampérométrique, procédé de remplacement d'une sonde utilisant cette connexion et sonde ampérométrique
EP0404860A1 (fr) Seringue comprenant un corps a chambre de volume variable et un dispositif d'aiguille assemblable audit corps
FR2593564A1 (fr) Ensemble cylindre-piston equipe de detecteurs de proximite de position reglable
EP0068963A1 (fr) Ferme-porte automatique à moyens de freinage incorporés
EP0001960A1 (fr) Système de fixation d'un appareil sur une cartouche de fluide sous pression
FR2653051A1 (fr) Dispositif de compression de ressorts.
FR2505944A1 (fr) Element temporisateur pneumatique
CA1067691A (fr) Tete micrometrique pour instrument de mesure d'interieurs
EP2600214A1 (fr) Mecanisme de transmission entre deux parties d'une tige de commande pour mouvement horloger
FR2958129A1 (fr) Applicateur cosmetique
FR2851497A1 (fr) Porte-cartouches et stylo-plume comprenant un tel porte-cartouches

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Designated state(s): AT BE CH DE GB IT LU NL SE

17P Request for examination filed

Effective date: 19810911

ITF It: translation for a ep patent filed
GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Designated state(s): AT BE CH DE GB IT LI LU NL SE

REF Corresponds to:

Ref document number: 3138

Country of ref document: AT

Date of ref document: 19830515

Kind code of ref document: T

REF Corresponds to:

Ref document number: 3062907

Country of ref document: DE

Date of ref document: 19830601

KL Correction list

Free format text: 83/04

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: LU

Payment date: 19831221

Year of fee payment: 4

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 19831231

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: AT

Payment date: 19921126

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 19921222

Year of fee payment: 13

ITTA It: last paid annual fee
PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 19921231

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: BE

Payment date: 19930115

Year of fee payment: 13

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Effective date: 19931229

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Effective date: 19931230

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Effective date: 19931231

BERE Be: lapsed

Owner name: MARTEAU D'AUTRY ERIC

Effective date: 19931231

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Effective date: 19940701

NLV4 Nl: lapsed or anulled due to non-payment of the annual fee
EUG Se: european patent has lapsed

Ref document number: 80401875.2

Effective date: 19940710

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 19991217

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 19991218

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 19991221

Year of fee payment: 20

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20001228

Ref country code: GB

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20001228

Ref country code: CH

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20001228

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: GB

Ref legal event code: PE20

Effective date: 20001228

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT