EG24122A - Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines - Google Patents

Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines

Info

Publication number
EG24122A
EG24122A EGNA2005000622A EG24122A EG 24122 A EG24122 A EG 24122A EG NA2005000622 A EGNA2005000622 A EG NA2005000622A EG 24122 A EG24122 A EG 24122A
Authority
EG
Egypt
Prior art keywords
quinolines
cyano
nitro
alkoxy
synthesis
Prior art date
Application number
Other languages
English (en)
Inventor
Scott M Duncan
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of EG24122A publication Critical patent/EG24122A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EGNA2005000622 2003-04-09 2005-10-05 Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines EG24122A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46164703P 2003-04-09 2003-04-09
PCT/US2004/010190 WO2004092138A1 (en) 2003-04-09 2004-04-02 Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines

Publications (1)

Publication Number Publication Date
EG24122A true EG24122A (en) 2008-07-06

Family

ID=33299849

Family Applications (1)

Application Number Title Priority Date Filing Date
EGNA2005000622 EG24122A (en) 2003-04-09 2005-10-05 Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines

Country Status (21)

Country Link
US (1) US6933388B2 (no)
EP (1) EP1611103A1 (no)
JP (1) JP2006522810A (no)
KR (1) KR20050120788A (no)
CN (1) CN100376558C (no)
AR (1) AR043988A1 (no)
AU (1) AU2004230864A1 (no)
BR (1) BRPI0409134A (no)
CA (1) CA2521294A1 (no)
CL (1) CL2004000758A1 (no)
CO (1) CO5640089A2 (no)
CR (1) CR7991A (no)
EC (1) ECSP056089A (no)
EG (1) EG24122A (no)
MX (1) MXPA05010685A (no)
NI (1) NI200500175A (no)
NO (1) NO20054375L (no)
RU (1) RU2333909C2 (no)
TW (1) TW200504024A (no)
UA (1) UA80607C2 (no)
WO (1) WO2004092138A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101723854A (zh) * 2008-10-24 2010-06-09 上海特化医药科技有限公司 6-取代氨基-3-氰基喹啉类化合物的制备方法及其中间体
CN111116416B (zh) * 2019-12-30 2021-03-23 中国农业大学 一种β-氨基丙烯腈类化合物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA73073C2 (uk) * 1997-04-03 2005-06-15 Уайт Холдінгз Корпорейшн Заміщені 3-ціанохіноліни, спосіб їх одержання та фармацевтична композиція
US6002008A (en) * 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
JP4537582B2 (ja) * 1998-09-29 2010-09-01 アメリカン・サイアナミド・カンパニー プロテインチロシンキナーゼインヒビターとしての置換３−シアノキノリン

Also Published As

Publication number Publication date
UA80607C2 (en) 2007-10-10
CO5640089A2 (es) 2006-05-31
ECSP056089A (es) 2006-03-01
RU2333909C2 (ru) 2008-09-20
AU2004230864A1 (en) 2004-10-28
RU2005134653A (ru) 2006-03-27
JP2006522810A (ja) 2006-10-05
TW200504024A (en) 2005-02-01
CA2521294A1 (en) 2004-10-28
KR20050120788A (ko) 2005-12-23
BRPI0409134A (pt) 2006-03-28
CN1771230A (zh) 2006-05-10
CR7991A (es) 2006-05-31
CN100376558C (zh) 2008-03-26
US20040204587A1 (en) 2004-10-14
EP1611103A1 (en) 2006-01-04
NI200500175A (es) 2006-05-04
NO20054375L (no) 2005-10-12
AR043988A1 (es) 2005-08-17
MXPA05010685A (es) 2005-12-12
WO2004092138A1 (en) 2004-10-28
US6933388B2 (en) 2005-08-23
CL2004000758A1 (es) 2005-02-04

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