EG19079A - Process for preparing of antibacterial 2 - carbapenem derivatives. - Google Patents

Process for preparing of antibacterial 2 - carbapenem derivatives.

Info

Publication number
EG19079A
EG19079A EG19490A EG19490A EG19079A EG 19079 A EG19079 A EG 19079A EG 19490 A EG19490 A EG 19490A EG 19490 A EG19490 A EG 19490A EG 19079 A EG19079 A EG 19079A
Authority
EG
Egypt
Prior art keywords
pref
antibacterial
preparing
methyl
formula
Prior art date
Application number
EG19490A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of EG19079A publication Critical patent/EG19079A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EG19490A 1989-03-28 1990-03-27 Process for preparing of antibacterial 2 - carbapenem derivatives. EG19079A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/001281 WO1990011284A1 (en) 1989-03-28 1989-03-28 Antibacterial 2-carbapenem derivatives

Publications (1)

Publication Number Publication Date
EG19079A true EG19079A (en) 1994-04-30

Family

ID=22214911

Family Applications (1)

Application Number Title Priority Date Filing Date
EG19490A EG19079A (en) 1989-03-28 1990-03-27 Process for preparing of antibacterial 2 - carbapenem derivatives.

Country Status (24)

Country Link
EP (1) EP0392681B1 (ko)
JP (1) JPH02286681A (ko)
KR (1) KR920002132B1 (ko)
CN (1) CN1024554C (ko)
AT (1) ATE100104T1 (ko)
AU (1) AU616345B2 (ko)
CA (1) CA2013024A1 (ko)
DD (1) DD293117A5 (ko)
DE (1) DE69005875T2 (ko)
DK (1) DK0392681T3 (ko)
EG (1) EG19079A (ko)
ES (1) ES2062340T3 (ko)
FI (1) FI914558A0 (ko)
HU (2) HU209817B (ko)
IE (1) IE901105L (ko)
IL (1) IL93835A0 (ko)
MX (1) MX20084A (ko)
NO (1) NO913815L (ko)
NZ (1) NZ233093A (ko)
PH (1) PH26902A (ko)
PT (1) PT93565A (ko)
WO (1) WO1990011284A1 (ko)
YU (1) YU59890A (ko)
ZA (1) ZA902347B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5317016A (en) * 1991-08-20 1994-05-31 Shionogi Seiyaku Kabushiki Kaisha Pyrrolidylthiocarbapenem derivative
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619924A (en) * 1984-05-18 1986-10-28 Pfizer Inc. 2-alkylthiopenem derivatives
US4757066A (en) * 1984-10-15 1988-07-12 Sankyo Company Limited Composition containing a penem or carbapenem antibiotic and the use of the same
US4665169A (en) * 1985-09-11 1987-05-12 Bristol-Myers Company Carbapenem antibiotics
EP0223397B1 (en) * 1985-10-17 1991-09-04 Pfizer Inc. Process for 2-(1-oxo-3-thiolanyl)-2-penem antibiotics
DE3775504D1 (en) * 1986-09-04 1992-02-06 Pfizer 2-(1-oxo-1-imino-1-thiacycloalkyl)-thiopenem-derivate.
US5013729A (en) * 1987-05-11 1991-05-07 Pfizer Inc. Diastereomeric 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylic acids

Also Published As

Publication number Publication date
EP0392681B1 (en) 1994-01-12
ZA902347B (en) 1991-11-27
NZ233093A (en) 1992-01-29
ATE100104T1 (de) 1994-01-15
ES2062340T3 (es) 1994-12-16
JPH02286681A (ja) 1990-11-26
FI914558A0 (fi) 1991-09-27
AU616345B2 (en) 1991-10-24
YU59890A (en) 1991-10-31
CA2013024A1 (en) 1990-09-28
IE901105L (en) 1990-09-28
DE69005875T2 (de) 1994-04-28
HU209817B (en) 1994-11-28
CN1046164A (zh) 1990-10-17
AU5229390A (en) 1990-10-04
DE69005875D1 (de) 1994-02-24
KR920002132B1 (ko) 1992-03-12
KR900014384A (ko) 1990-10-23
HUT63167A (en) 1993-07-28
PH26902A (en) 1992-12-03
CN1024554C (zh) 1994-05-18
HU895565D0 (en) 1992-07-28
IL93835A0 (en) 1990-12-23
NO913815D0 (no) 1991-09-27
NO913815L (no) 1991-11-27
WO1990011284A1 (en) 1990-10-04
EP0392681A1 (en) 1990-10-17
DD293117A5 (de) 1991-08-22
DK0392681T3 (da) 1994-03-21
HUT64070A (en) 1993-11-29
PT93565A (pt) 1990-11-07
MX20084A (es) 1993-03-01

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