EG17345A - Compositions and methods of enhancing transdermal and transmembrane penetration of topical and systemic agents - Google Patents

Compositions and methods of enhancing transdermal and transmembrane penetration of topical and systemic agents

Info

Publication number
EG17345A
EG17345A EG358/85A EG35885A EG17345A EG 17345 A EG17345 A EG 17345A EG 358/85 A EG358/85 A EG 358/85A EG 35885 A EG35885 A EG 35885A EG 17345 A EG17345 A EG 17345A
Authority
EG
Egypt
Prior art keywords
topical
compositions
methods
systemic agents
enhancing transdermal
Prior art date
Application number
EG358/85A
Other languages
English (en)
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of EG17345A publication Critical patent/EG17345A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
EG358/85A 1984-06-13 1985-06-13 Compositions and methods of enhancing transdermal and transmembrane penetration of topical and systemic agents EG17345A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/620,229 US4743588A (en) 1984-06-13 1984-06-13 Compositions and methods of enhancing transdermal and transmembrane penetration systemic agents

Publications (1)

Publication Number Publication Date
EG17345A true EG17345A (en) 1991-03-30

Family

ID=24485099

Family Applications (1)

Application Number Title Priority Date Filing Date
EG358/85A EG17345A (en) 1984-06-13 1985-06-13 Compositions and methods of enhancing transdermal and transmembrane penetration of topical and systemic agents

Country Status (16)

Country Link
US (1) US4743588A (el)
EP (1) EP0164998A3 (el)
JP (1) JPS611623A (el)
KR (1) KR860000065A (el)
AU (1) AU582364B2 (el)
CA (1) CA1255594A (el)
DK (1) DK259485A (el)
EG (1) EG17345A (el)
FI (1) FI852331L (el)
GR (1) GR851421B (el)
HU (1) HU193774B (el)
IL (1) IL75488A (el)
NZ (1) NZ212368A (el)
PT (1) PT80625B (el)
ZA (1) ZA854365B (el)
ZW (1) ZW9985A1 (el)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837026A (en) * 1985-10-03 1989-06-06 Rajakhyaksha Vithal J Transdermal and systemic preparation and method
US5204339A (en) * 1986-01-31 1993-04-20 Whitby Research, Inc. Penetration enhancers for transdermal delivery of systemic agents
JPS63502282A (ja) * 1986-01-31 1988-09-01 ホイットビ−・リサ−チ・インコ−ポレ−テッド １−置換アザシクロアルカン類より成る組成物とその用法
CA1298557C (en) * 1986-01-31 1992-04-07 Whitby Research Incorporated Compositions comprising 1-substituted azacyclo-alkanes
NZ220495A (en) * 1986-05-30 1990-07-26 Univ California A2a cyclopeptan-2-ones carrier containing methotrexate compositions
CA1308352C (en) * 1986-08-15 1992-10-06 James V. Peck Compositions comprising 1-oxohydrocarbyl-substituted azacyclohexanes
US4917896A (en) * 1986-08-15 1990-04-17 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agents
US4808414A (en) * 1986-09-29 1989-02-28 Nelson Research & Development Co. Amide penetration enhancers for transdermal delivery of systemic agents
DE3778833D1 (de) * 1986-11-19 1992-06-11 Whitby Research Inc Penetrationsverbesserer fuer die transdermale verabreichung von systemisch wirksamen arzneimitteln.
EP0268219A1 (en) * 1986-11-19 1988-05-25 Whitby Research Incorporated Penetration enhancers for transdermal delivery of systemic agents
US5112804A (en) * 1987-04-01 1992-05-12 Temple University Of The Commonwealth System Of Higher Education Pharmaceutical composition and method of intranasal administration
US4920101A (en) * 1987-09-30 1990-04-24 Nelson Research & Development Co. Compositions comprising 1-oxo- or thiohydrocarbyl substituted azacycloaklkanes
US4879275A (en) * 1987-09-30 1989-11-07 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agent
CA1334646C (en) * 1988-04-08 1995-03-07 James Vanolden Peck Transdermal penetration enhancers
EP0425505B1 (en) * 1988-06-30 1993-03-17 The Upjohn Company Transdermal antisecretory agents for gastrointestinal disease
US5059603A (en) * 1989-06-12 1991-10-22 Centuries Laboratories, Inc. Method and composition for treating impotence
US5981591A (en) * 1992-12-04 1999-11-09 Mayor Pharmaceutical Laboratories, Inc. Sprayable analgesic composition and method of use
US6767925B1 (en) 1996-10-31 2004-07-27 Joseph A. Deihl Sprayable analgesic composition and method of use
US20060002959A1 (en) * 1996-11-14 2006-01-05 Government Of The United States Skin-sctive adjuvants for transcutaneous immuization
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US20060002949A1 (en) * 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
CN1172674C (zh) 1997-11-10 2004-10-27 赛勒吉药物股份有限公司 促进渗透和减少刺激的系统
US20040258703A1 (en) * 1997-11-14 2004-12-23 The Government Of The Us, As Represented By The Secretary Of The Army Skin-active adjuvants for transcutaneous immunization
US6262117B1 (en) 1999-02-18 2001-07-17 Allergan Sales, Inc. Method and composition for treating acne
JP4932086B2 (ja) * 1999-04-08 2012-05-16 インターセル ユーエスエイ、インコーポレイテッド 経皮的免疫のための乾燥製剤
WO2002064162A2 (en) * 2001-02-13 2002-08-22 Government Of The United States, As Represented By The Secretary Of The Army Vaccine for transcutaneous immunization
US6521613B2 (en) 2001-04-10 2003-02-18 Allergan, Inc. Lactam compounds for penetration enhancement
US20030175329A1 (en) * 2001-10-04 2003-09-18 Cellegy Pharmaceuticals, Inc. Semisolid topical hormonal compositions and methods for treatment
US20060222692A1 (en) * 2005-03-31 2006-10-05 Fairfield Clinical Trials Llc Method and compositions for transdermal administration of antimicrobial medications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3223708A (en) * 1962-05-24 1965-12-14 Robert R Mod N-decanoyltetrahydroquinoline
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
DE3009546A1 (de) * 1980-03-13 1981-09-24 Henkel KGaA, 4000 Düsseldorf Desodorierende kosmetische zusammensetzungen

Also Published As

Publication number Publication date
ZW9985A1 (en) 1985-09-04
DK259485A (da) 1985-12-14
KR860000065A (ko) 1986-01-25
HUT38543A (en) 1986-06-30
CA1255594A (en) 1989-06-13
JPS611623A (ja) 1986-01-07
AU4345285A (en) 1985-12-19
NZ212368A (en) 1988-03-30
GR851421B (el) 1985-11-25
IL75488A (en) 1989-07-31
EP0164998A2 (en) 1985-12-18
FI852331A0 (fi) 1985-06-12
US4743588A (en) 1988-05-10
PT80625A (en) 1985-07-01
EP0164998A3 (en) 1987-06-16
FI852331L (fi) 1985-12-14
ZA854365B (en) 1986-05-28
DK259485D0 (da) 1985-06-10
AU582364B2 (en) 1989-03-23
HU193774B (en) 1987-11-30
PT80625B (en) 1987-03-26

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