EE9900036A - Novel compounds and compositions for the treatment of diseases associated with tryptase activity - Google Patents
Novel compounds and compositions for the treatment of diseases associated with tryptase activityInfo
- Publication number
- EE9900036A EE9900036A EEP199900036A EE9900036A EE9900036A EE 9900036 A EE9900036 A EE 9900036A EE P199900036 A EEP199900036 A EE P199900036A EE 9900036 A EE9900036 A EE 9900036A EE 9900036 A EE9900036 A EE 9900036A
- Authority
- EE
- Estonia
- Prior art keywords
- compositions
- treatment
- novel compounds
- diseases associated
- tryptase activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
- C07D233/08—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
- C07D233/12—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D233/14—Radicals substituted by oxygen atoms
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2313996P | 1996-07-30 | 1996-07-30 | |
| US89577297A | 1997-07-17 | 1997-07-17 | |
| PCT/US1997/013422 WO1998004537A1 (en) | 1996-07-30 | 1997-07-30 | Novel compounds and compositions for treating diseases associated with tryptase activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE9900036A true EE9900036A (en) | 1999-08-16 |
Family
ID=26696778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP199900036A EE9900036A (en) | 1996-07-30 | 1997-07-30 | Novel compounds and compositions for the treatment of diseases associated with tryptase activity |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0934293A1 (en) |
| JP (1) | JP2001509787A (en) |
| KR (1) | KR20000029679A (en) |
| CN (1) | CN1073103C (en) |
| AU (1) | AU733621B2 (en) |
| CA (1) | CA2262542A1 (en) |
| CZ (1) | CZ29799A3 (en) |
| EE (1) | EE9900036A (en) |
| FI (1) | FI990171A (en) |
| HU (1) | HUP0003267A3 (en) |
| LV (1) | LV12291B (en) |
| NO (1) | NO990433L (en) |
| NZ (1) | NZ333713A (en) |
| PL (1) | PL331465A1 (en) |
| SI (1) | SI9720047A (en) |
| SK (1) | SK8599A3 (en) |
| WO (1) | WO1998004537A1 (en) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221914B1 (en) | 1997-11-10 | 2001-04-24 | Array Biopharma Inc. | Sulfonamide bridging compounds that inhibit tryptase activity |
| AU2723099A (en) * | 1998-02-06 | 1999-08-23 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tryptase inhibitors |
| AU2924699A (en) * | 1998-02-06 | 1999-08-23 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tryptase inhibitors |
| AU5625499A (en) * | 1998-09-04 | 2000-03-27 | Altana Pharma Ag | Novel pyranoses |
| ATE279398T1 (en) * | 1999-08-10 | 2004-10-15 | Altana Pharma Ag | DIAZOCINDIONE DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS |
| JP2003509417A (en) * | 1999-09-14 | 2003-03-11 | アルタナ ファルマ アクチエンゲゼルシャフト | Tryptase inhibitor |
| WO2001036386A1 (en) * | 1999-11-17 | 2001-05-25 | Sumitomo Pharmaceuticals Co., Ltd. | Diabetic remedy containing dipiperazine derivative |
| DE19955476A1 (en) * | 1999-11-18 | 2001-05-23 | Boehringer Ingelheim Pharma | Bis-basic compounds as tryptase inhibitors, process for their preparation and their use as medicaments |
| JP2003518087A (en) | 1999-12-20 | 2003-06-03 | アルタナ ファルマ アクチエンゲゼルシャフト | Tryptase inhibitor |
| TR200402322T4 (en) * | 1999-12-20 | 2004-12-21 | Altana Pharma Ag | Tryptase inhibitors |
| CA2438594A1 (en) | 2001-01-31 | 2002-08-08 | Altana Pharma Ag | Diazocine derivatives and their use as tryptase inhibitors |
| AU2002253026B2 (en) | 2001-02-21 | 2007-08-09 | Altana Pharma Ag | Tryptase inhibitors |
| US7060716B2 (en) | 2001-02-21 | 2006-06-13 | Altana Pharma Ag | Tryptase inhibitors |
| JP2004525926A (en) * | 2001-03-15 | 2004-08-26 | アルタナ ファルマ アクチエンゲゼルシャフト | Tryptase inhibitor |
| WO2002074732A2 (en) * | 2001-03-15 | 2002-09-26 | Altana Pharma Ag | Tryptase-inhibitors |
| HUP0400167A3 (en) | 2001-06-11 | 2012-09-28 | Xenoport Inc | Prodrugs of gaba analogs, compositions and uses thereof |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| JP2005508871A (en) | 2001-06-19 | 2005-04-07 | アルタナ ファルマ アクチエンゲゼルシャフト | Tryptase inhibitor |
| BRPI0517227B8 (en) | 2004-11-04 | 2021-05-25 | Xenoport Inc | 1-{[alpha-isobutanoyloxyethoxy)carbonyl]amino methyl}-1-acetic acid extended-release tablet, and use of the tablet |
| JP5385402B2 (en) * | 2008-12-19 | 2014-01-08 | メルツ・ファルマ・ゲゼルシヤフト・ミト・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト・アウフ・アクティーン | 1-amino-alkylcyclohexane derivatives for the treatment of mast cell mediated diseases |
| TWI432188B (en) | 2008-12-19 | 2014-04-01 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of inflammatory skin diseases |
| FR3038605B1 (en) | 2015-07-06 | 2018-08-24 | Universite Amiens Picardie Jules Verne | VICINAL PRIMARY DIAMINS ASSOCIATED WITH CHELATING MOTIFS OF METALS AND / OR FREE RADICALS, ACTIVE AGAINST CARBONYL AND OXIDIZING STRESSES AND THEIR USE |
| JP7373191B2 (en) * | 2017-05-12 | 2023-11-02 | 国立研究開発法人理化学研究所 | Class A GPCR-binding compound variants |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845242A (en) * | 1987-04-28 | 1989-07-04 | Georgia Tech Research Corporation | Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents |
| US5525623A (en) * | 1993-03-12 | 1996-06-11 | Arris Pharmaceutical Corporation | Compositions and methods for the treatment of immunomediated inflammatory disorders |
| EP0688337A1 (en) * | 1993-03-12 | 1995-12-27 | Arris Pharmaceutical Corporation | Compositions and methods for the treatment of immunomediated inflammatory disorders |
| EP0763016B1 (en) * | 1994-06-01 | 2000-01-26 | Axys Pharmaceuticals, Inc. | Compositions and methods for treating mast-cell mediated conditions |
| RU2159229C2 (en) * | 1994-09-23 | 2000-11-20 | Эксис Фармасьютикалз, Инк. | Cycloalkylene or heterocycloalkylene derivatives, pharmaceutical composition, aerosol device, and medical treatment method |
| PL322409A1 (en) * | 1995-03-24 | 1998-01-19 | Arris Pharm Corp | Reversible protease inhibitors |
| TW438591B (en) * | 1995-06-07 | 2001-06-07 | Arris Pharm Corp | Reversible cysteine protease inhibitors |
-
1997
- 1997-07-30 EP EP97937066A patent/EP0934293A1/en not_active Withdrawn
- 1997-07-30 KR KR1019997000757A patent/KR20000029679A/en not_active Application Discontinuation
- 1997-07-30 WO PCT/US1997/013422 patent/WO1998004537A1/en not_active Application Discontinuation
- 1997-07-30 NZ NZ333713A patent/NZ333713A/en unknown
- 1997-07-30 JP JP50913698A patent/JP2001509787A/en active Pending
- 1997-07-30 SK SK85-99A patent/SK8599A3/en unknown
- 1997-07-30 PL PL97331465A patent/PL331465A1/en unknown
- 1997-07-30 AU AU39670/97A patent/AU733621B2/en not_active Ceased
- 1997-07-30 CZ CZ99297A patent/CZ29799A3/en unknown
- 1997-07-30 CA CA002262542A patent/CA2262542A1/en not_active Abandoned
- 1997-07-30 HU HU0003267A patent/HUP0003267A3/en unknown
- 1997-07-30 SI SI9720047A patent/SI9720047A/en unknown
- 1997-07-30 EE EEP199900036A patent/EE9900036A/en unknown
- 1997-07-30 CN CN97196877A patent/CN1073103C/en not_active Expired - Fee Related
-
1999
- 1999-01-29 NO NO990433A patent/NO990433L/en not_active Application Discontinuation
- 1999-01-29 FI FI990171A patent/FI990171A/en unknown
- 1999-02-18 LV LVP-99-27A patent/LV12291B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1073103C (en) | 2001-10-17 |
| FI990171A (en) | 1999-03-23 |
| LV12291B (en) | 2000-04-20 |
| AU733621B2 (en) | 2001-05-17 |
| PL331465A1 (en) | 1999-07-19 |
| CN1226892A (en) | 1999-08-25 |
| NO990433D0 (en) | 1999-01-29 |
| SK8599A3 (en) | 2000-03-13 |
| FI990171A0 (en) | 1999-01-29 |
| NO990433L (en) | 1999-03-25 |
| SI9720047A (en) | 1999-08-31 |
| CZ29799A3 (en) | 1999-06-16 |
| HUP0003267A3 (en) | 2002-02-28 |
| CA2262542A1 (en) | 1998-02-05 |
| KR20000029679A (en) | 2000-05-25 |
| AU3967097A (en) | 1998-02-20 |
| LV12291A (en) | 1999-06-20 |
| JP2001509787A (en) | 2001-07-24 |
| NZ333713A (en) | 2000-12-22 |
| HUP0003267A2 (en) | 2001-06-28 |
| EP0934293A1 (en) | 1999-08-11 |
| WO1998004537A1 (en) | 1998-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EE9900036A (en) | Novel compounds and compositions for the treatment of diseases associated with tryptase activity | |
| DE69509544T2 (en) | COMPOSITION FOR THE TREATMENT OF OVARIAL OSTROGEN-DEPENDENT DISEASES | |
| FI953180A0 (en) | Compositions for the treatment of diabetic complications | |
| DE69117117D1 (en) | Cleaning composition for the prevention and alleviation of skin irritation | |
| NO20006630L (en) | Pharmaceutical composition for the treatment of diabetes | |
| FI971969A0 (en) | Compositions and method of use for the treatment of hemorrhoids | |
| PT934057E (en) | MEDICAL FORMULATIONS OF AEROSOLS WITH FORMOTEROL | |
| DE69812784D1 (en) | Composition for the prevention and elimination of plant diseases | |
| EE04055B1 (en) | Compounds and compositions for the treatment of diseases associated with serine protease activity, in particular tryptase activity, and their use | |
| NO965564D0 (en) | Medical application of bromelain | |
| DE69620691T2 (en) | Therapeutic agent for the treatment of hypercholesterolemia | |
| DE69405919D1 (en) | Compositions for the treatment of keratin fibers | |
| NO991459D0 (en) | Use of 1-hydroxy-2-pyridones for the treatment of skin infections | |
| DE69807466T2 (en) | TRIPTOLID DERIVATIVES USEFUL FOR THE TREATMENT OF AUTOIMMUNE DISEASES | |
| DE69822297D1 (en) | TRIPTOLID DERIVATIVES SUITABLE FOR THE TREATMENT OF AUTOIMMUNE DISEASES | |
| DE69913380D1 (en) | COMPOSITION FOR THE TREATMENT OF PERIODONTAL DISEASES | |
| HUP0000785A3 (en) | Ointment for the treatment of burns and other skin diseases | |
| NO982562D0 (en) | Composition for the treatment of pain | |
| NO963482D0 (en) | Medical application of bromelain | |
| BR9507732A (en) | Pharmaceutical composition for the treatment of glaucoma | |
| DE69813354T2 (en) | Agents for the treatment of heart diseases | |
| NO970127D0 (en) | Topical compositions for the treatment of skin disease | |
| LT99019A (en) | Novel compounds and compositions for treating diseases associated with tryptase activity | |
| ID24439A (en) | USE OF TIAZOLIDINDION FOR HYPERGLICEMIA TREATMENT | |
| DE69822628D1 (en) | PYRROLO [2.1.5-CD] INDOLICINE DERIVATIVES USEFUL FOR THE PREVENTION OR TREATMENT OF ESTROGEN-DEPENDENT DISEASES |