EE200300059A - Compounds containing a perfluoroalkyl group containing carbohydrate residues, their preparation method and their use - Google Patents

Compounds containing a perfluoroalkyl group containing carbohydrate residues, their preparation method and their use

Info

Publication number
EE200300059A
EE200300059A EEP200300059A EEP200300059A EE200300059A EE 200300059 A EE200300059 A EE 200300059A EE P200300059 A EEP200300059 A EE P200300059A EE P200300059 A EEP200300059 A EE P200300059A EE 200300059 A EE200300059 A EE 200300059A
Authority
EE
Estonia
Prior art keywords
preparation
perfluoroalkyl group
carbohydrate residues
group containing
compounds containing
Prior art date
Application number
EEP200300059A
Other languages
Estonian (et)
Inventor
Platzek Johannes
Mareski Peter
Niedballa Ulrich
Rad�chel Bernd
Weinmann Hanns-Joachim
Misselwitz Bernd
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of EE200300059A publication Critical patent/EE200300059A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200300059A 2000-08-11 2001-07-23 Compounds containing a perfluoroalkyl group containing carbohydrate residues, their preparation method and their use EE200300059A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10040381A DE10040381C1 (en) 2000-08-11 2000-08-11 Perfluoroalkyl-containing complexes with sugar residues, process for their preparation and their use
PCT/EP2001/008499 WO2002014309A1 (en) 2000-08-11 2001-07-23 Perfluoroalkyl-containing complexes comprising sugar residues, method for producing the same and use thereof

Publications (1)

Publication Number Publication Date
EE200300059A true EE200300059A (en) 2004-12-15

Family

ID=7652861

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300059A EE200300059A (en) 2000-08-11 2001-07-23 Compounds containing a perfluoroalkyl group containing carbohydrate residues, their preparation method and their use

Country Status (31)

Country Link
EP (1) EP1307446B1 (en)
JP (1) JP2004506631A (en)
KR (1) KR100820387B1 (en)
CN (1) CN1249058C (en)
AR (1) AR035579A1 (en)
AT (1) ATE293623T1 (en)
AU (2) AU2001289729B2 (en)
BG (1) BG107540A (en)
BR (1) BR0113192A (en)
CA (1) CA2418790A1 (en)
CZ (1) CZ2003340A3 (en)
DE (2) DE10040381C1 (en)
DK (1) DK1307446T3 (en)
EE (1) EE200300059A (en)
ES (1) ES2240517T3 (en)
HK (1) HK1062016A1 (en)
HR (1) HRP20030172A2 (en)
HU (1) HUP0300744A3 (en)
IL (1) IL154328A0 (en)
MX (1) MXPA03001285A (en)
NO (1) NO20030648L (en)
NZ (1) NZ524079A (en)
PL (1) PL360359A1 (en)
PT (1) PT1307446E (en)
RU (1) RU2280644C2 (en)
SK (1) SK1542003A3 (en)
TW (1) TWI243170B (en)
UA (1) UA75364C2 (en)
WO (1) WO2002014309A1 (en)
YU (1) YU10403A (en)
ZA (1) ZA200301948B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19948651B4 (en) * 1999-09-29 2006-10-05 Schering Ag Galenic formulations containing para and diamagnetic perfluorinated compounds, their preparation and use
DE10231799B4 (en) * 2002-07-10 2006-10-05 Schering Ag Use of perfluoroalkyl-containing metal complexes as contrast agents in MR imaging for the presentation of intravascular thrombi
US7344704B2 (en) 2002-07-10 2008-03-18 Schering Ag Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi
DE10260372B4 (en) 2002-12-13 2007-01-04 Schering Ag Magnetic resonance imaging apparatus and method for spatially resolved imaging
JP2009509915A (en) * 2005-07-15 2009-03-12 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト Perfluoroalkyl-containing complexes and their use as contrast agents for NMR, X-ray and radiodiagnosis as well as radiotherapy
DE102006049821A1 (en) * 2006-10-18 2008-04-24 Bayer Schering Pharma Aktiengesellschaft New, well tolerated metal chelates, for use as radiodiagnostic, radiotherapeutic or NMR and X-ray diagnostic agents, contain chelator and perfluorinated polyethylene glycol residues
US20100215581A1 (en) * 2006-10-25 2010-08-26 Koninklijke Philips Electronics N.V. Contrast agents for detecting prostate cancer
DE102008024976A1 (en) 2008-05-23 2009-12-17 Marvis Technologies Gmbh Medical instrument
JP2011190183A (en) * 2010-03-11 2011-09-29 Noguchi Institute Fluorous sugar-bonded crown ether derivative
EP2450067A1 (en) 2010-10-18 2012-05-09 MaRVis Technologies GmbH Medical device
EP2484388A1 (en) 2011-02-05 2012-08-08 MaRVis Technologies GmbH Implantable or insertable MRI-detectable medical device having a coating comprising paramagnetic ions and a process for preparing it
EP2692365A1 (en) 2012-08-03 2014-02-05 MaRVis Medical GmbH Implantable or insertable MRI-detectable medical device having a coating comprising paramagnetic ions and a process for preparing it
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
WO2018096082A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
CA3120665A1 (en) 2018-11-23 2020-05-28 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
DE68901924T2 (en) * 1988-01-26 1992-12-10 Nycomed As PARAMAGNETIC CONNECTIONS.
CA2069886A1 (en) * 1989-10-23 1991-04-24 David Love Multi-site metal chelating agents
US5330743A (en) * 1992-11-12 1994-07-19 Magnetic Research, Inc. Aminosaccharide contrast agents for magnetic resonance images
IL115670A (en) * 1994-10-21 1999-11-30 Nihon Mediphysics Co Ltd Diagnostic imaging agent
DE19603033A1 (en) * 1996-01-19 1997-07-24 Schering Ag Perfluoroalkyl-containing metal complexes, processes for their preparation and their use in NMR diagnostics
DE19728954C1 (en) * 1997-06-30 1999-04-22 Schering Ag Saccharide conjugates, pharmaceutical compositions containing them, processes for their preparation and their use
DE19729013A1 (en) * 1997-07-03 1999-02-04 Schering Ag Oligomeric, perfluoroalkyl-containing compounds, processes for their preparation and their use in NMR diagnostics
DE19744004C1 (en) * 1997-09-26 1999-07-22 Schering Ag Lipophilic metal complexes for necrosis and infarct imaging
DE19758105A1 (en) * 1997-12-18 1999-06-24 Schering Ag New dendritic polymer-saccharide conjugates
DE19914101C1 (en) * 1999-03-22 2000-10-12 Schering Ag Perfluoroalkylamides, their preparation and their use in diagnostics
DE19948651B4 (en) * 1999-09-29 2006-10-05 Schering Ag Galenic formulations containing para and diamagnetic perfluorinated compounds, their preparation and use

Also Published As

Publication number Publication date
DE10040381C1 (en) 2002-06-06
JP2004506631A (en) 2004-03-04
EP1307446B1 (en) 2005-04-20
CN1249058C (en) 2006-04-05
CN1468234A (en) 2004-01-14
PT1307446E (en) 2005-08-31
HRP20030172A2 (en) 2005-04-30
ATE293623T1 (en) 2005-05-15
IL154328A0 (en) 2003-09-17
ES2240517T3 (en) 2005-10-16
KR100820387B1 (en) 2008-04-08
AU2001289729B2 (en) 2006-11-16
NO20030648D0 (en) 2003-02-10
BR0113192A (en) 2003-07-15
AU8972901A (en) 2002-02-25
BG107540A (en) 2003-11-28
HUP0300744A3 (en) 2009-01-28
MXPA03001285A (en) 2004-05-17
WO2002014309A1 (en) 2002-02-21
NO20030648L (en) 2003-04-11
SK1542003A3 (en) 2003-10-07
CA2418790A1 (en) 2003-02-07
CZ2003340A3 (en) 2003-09-17
DE50105965D1 (en) 2005-05-25
TWI243170B (en) 2005-11-11
EP1307446A1 (en) 2003-05-07
YU10403A (en) 2006-05-25
HK1062016A1 (en) 2004-10-15
UA75364C2 (en) 2006-04-17
PL360359A1 (en) 2004-09-06
AR035579A1 (en) 2004-06-16
RU2280644C2 (en) 2006-07-27
NZ524079A (en) 2005-10-28
HUP0300744A2 (en) 2003-09-29
KR20030024855A (en) 2003-03-26
ZA200301948B (en) 2004-06-25
DK1307446T3 (en) 2005-08-15

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