EE200200583A - Method for the preparation of (E) -N- (6,6-dimethyl-2-hepten-4-ynyl) -N-methyl-1-naphthalenemethanamine (terbinafine) - Google Patents

Method for the preparation of (E) -N- (6,6-dimethyl-2-hepten-4-ynyl) -N-methyl-1-naphthalenemethanamine (terbinafine)

Info

Publication number
EE200200583A
EE200200583A EEP200200583A EEP200200583A EE200200583A EE 200200583 A EE200200583 A EE 200200583A EE P200200583 A EEP200200583 A EE P200200583A EE P200200583 A EEP200200583 A EE P200200583A EE 200200583 A EE200200583 A EE 200200583A
Authority
EE
Estonia
Prior art keywords
naphthalenemethanamine
hepten
terbinafine
ynyl
dimethyl
Prior art date
Application number
EEP200200583A
Other languages
Estonian (et)
Inventor
Kakal�k Ivan
Oremus Vladim�r
�mahovsk Vendel
�nup�rek Vladislav
Vand�k Du�an
Varga Ivan
Zem�nek Mari�n
�talmach Valdemar
Jezek Ladislav
Original Assignee
Slovakofarma A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Slovakofarma A.S. filed Critical Slovakofarma A.S.
Publication of EE200200583A publication Critical patent/EE200200583A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EEP200200583A 2000-04-07 2001-04-05 Method for the preparation of (E) -N- (6,6-dimethyl-2-hepten-4-ynyl) -N-methyl-1-naphthalenemethanamine (terbinafine) EE200200583A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SK520-2000A SK5202000A3 (en) 2000-04-07 2000-04-07 Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4- inyl)-n-methyl-1-naphthalenemethylamine (terbinaphin)
PCT/SK2001/000008 WO2001077064A1 (en) 2000-04-07 2001-04-05 Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine (terbinafine)

Publications (1)

Publication Number Publication Date
EE200200583A true EE200200583A (en) 2004-04-15

Family

ID=20435846

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200583A EE200200583A (en) 2000-04-07 2001-04-05 Method for the preparation of (E) -N- (6,6-dimethyl-2-hepten-4-ynyl) -N-methyl-1-naphthalenemethanamine (terbinafine)

Country Status (7)

Country Link
AU (1) AU2001248998A1 (en)
EE (1) EE200200583A (en)
HU (1) HUP0302919A3 (en)
LT (1) LT5051B (en)
LV (1) LV12955B (en)
SK (1) SK5202000A3 (en)
WO (1) WO2001077064A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100459275B1 (en) * 2001-12-28 2004-12-03 주식회사유한양행 A PROCESS FOR THE PREPARATION OF TERBINAFINE OR HCl SALT THEREOF
KR20030066186A (en) * 2002-02-05 2003-08-09 한솔케미언스 주식회사 Process for preparation of Terbinafin
ITMI20022534A1 (en) 2002-11-29 2004-05-30 Dinamite Dipharma S P A PROCEDURE FOR THE PREPARATION OF TERBINAFINA BY USING PLATINUM AS A CATALYST.
UA93892C2 (en) * 2005-10-31 2011-03-25 Янссен Фармацевтика H.B. Processes for the preparation of cyclopropyl-amide derivatives
EA014905B1 (en) * 2005-10-31 2011-02-28 Янссен Фармацевтика Н.В. Novel processes for the preparation of piperazinyl benzamide derivatives
CN101624328B (en) * 2009-07-31 2011-12-14 山东铂源化学有限公司 Method for synthesizing (E)-1-chlorine-6, 6-dimethyl-2-heptylene-4-alkyne
CN104725240B (en) * 2015-02-12 2017-05-24 吉林修正药业新药开发有限公司 Method for preparing terbinafine hydrochloride Z-shaped isomer
CN105016966A (en) * 2015-07-31 2015-11-04 江苏恒润制药有限公司 Preparation method of (E)-1-chloro-6,6-dimethyl-2-heptene-4-alkyne
CN111153807B (en) * 2020-01-16 2023-01-06 河南豫辰药业股份有限公司 Preparation method of N, N-dimethylamino chloropropane hydrochloride

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1410A (en) 1979-08-22 1988-04-22 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
CH678527A5 (en) 1989-06-22 1991-09-30 Sandoz Ag Trans(E)-N-(1-naphthyl:methyl)-heptenyl-amine prepn. - by simultaneously converting crude mixt. contg. cis and trans isomers to salt and precipitating trans isomer
JP3116364B2 (en) * 1989-10-02 2000-12-11 萬有製薬株式会社 Method for producing enyne derivatives
NZ280065A (en) 1995-09-20 1998-04-27 Apotex Inc Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives

Also Published As

Publication number Publication date
LT5051B (en) 2003-08-25
SK5202000A3 (en) 2001-12-03
HUP0302919A2 (en) 2003-12-29
WO2001077064A8 (en) 2002-01-03
HUP0302919A3 (en) 2004-09-28
LV12955B (en) 2003-04-20
LT2002103A (en) 2003-05-26
AU2001248998A1 (en) 2001-10-23
WO2001077064A1 (en) 2001-10-18

Similar Documents

Publication Publication Date Title
IS2940B (en) Antibodies against CD40
EE200200704A (en) New compounds, process for their preparation and their use
EE200200470A (en) New compounds, process for their preparation and their use
NO20035775L (en) 3-fluoro-pyrrolidines as anti-diabetic agents
DE50202328D1 (en) AMIDOFUNCTIONAL AMINOPOLYDIORGANOSILOXANE
NO20035208D0 (en) New vaccine preparation
NO20031573L (en) Alpha-aryl ethanolamines and their use as beta-3 adrenergic receptor agonists
NO20031273D0 (en) Substituted cinnamic acid guanidines, process for their preparation, their use as drug and drug containing the same
IT1317716B1 (en) PROCESS FOR THE PREPARATION OF OXYDRYL CONTERMINAL PERFLUOROPOLYXIALKYLENES.
DE50209888D1 (en) printing process
BR0211391B1 (en) process for preparing 4-aminodiphenylamines.
DK1330458T3 (en) N- (1,2,4-triazoloazinyl) thiophenesulfonamide compounds as herbicides
BR0213561B1 (en) process for the preparation of 2-halopyridecarboxylic acid amides.
EE200200583A (en) Method for the preparation of (E) -N- (6,6-dimethyl-2-hepten-4-ynyl) -N-methyl-1-naphthalenemethanamine (terbinafine)
PT1432682E (en) PROCESS FOR THE PREPARATION OF REPAGLINIDA
IT1319671B1 (en) PROCESS FOR THE PREPARATION OF (S) -N, N'-BIS (2-IDROSSI-1- (IDROSSIMETIL) ETIL) -5 - ((2-IDROSSI-1-OSSOPROPIL) AMINO)
DK1098891T3 (en) Polycyclic thiazolidin-2-ylidene amines, process for their preparation and their use as drugs
EE200200697A (en) New compounds, process for their preparation and their use
NO20030868D0 (en) N- (3,5-dichloro-2-methoxyphenyl) -4-methoxy-3-piperazin-1-yl-benzenesulfonamide
PT1292586E (en) PROCESS FOR THE PREPARATION OF PYRAZOLOPYRYIDINONES
PT1363516E (en) AN IMPROVED PROCESS FOR THE PREPARATION OF SINVASTATIN
DK1373232T3 (en) Process for the preparation of N-substituted 2,6-dialkylmorpholines
ITMI20021031A0 (en) PROCEDURE FOR PREPARING POLYCARBONATE-POLYOLS
BR0111039B1 (en) Process for the preparation of 2-chloro-5-chloromethyl-1,3-thiazole.
DK1429753T3 (en) Pharmaceutical composition comprising gamma-butyrobetaine