AU2001248998A1 - Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1- naphthalenemethanamine (terbinafine) - Google Patents

Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1- naphthalenemethanamine (terbinafine)

Info

Publication number
AU2001248998A1
AU2001248998A1 AU2001248998A AU4899801A AU2001248998A1 AU 2001248998 A1 AU2001248998 A1 AU 2001248998A1 AU 2001248998 A AU2001248998 A AU 2001248998A AU 4899801 A AU4899801 A AU 4899801A AU 2001248998 A1 AU2001248998 A1 AU 2001248998A1
Authority
AU
Australia
Prior art keywords
naphthalenemethanamine
hepten
terbinafine
ynyl
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001248998A
Inventor
Ladislav Jezek
Ivan Kakalik
Vladimir Oremus
Vendel Smahovsk
Vladislav Snuparek
Valdemar Swtalmach
Dusan Vandak
Ivan Varga
Marian Zemanek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zentiva KS
Original Assignee
Slovakofarma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Slovakofarma AS filed Critical Slovakofarma AS
Publication of AU2001248998A1 publication Critical patent/AU2001248998A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
AU2001248998A 2000-04-07 2001-04-05 Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1- naphthalenemethanamine (terbinafine) Abandoned AU2001248998A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SK520-2000A SK5202000A3 (en) 2000-04-07 2000-04-07 Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4- inyl)-n-methyl-1-naphthalenemethylamine (terbinaphin)
SKPV0520-2000 2000-04-07
PCT/SK2001/000008 WO2001077064A1 (en) 2000-04-07 2001-04-05 Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine (terbinafine)

Publications (1)

Publication Number Publication Date
AU2001248998A1 true AU2001248998A1 (en) 2001-10-23

Family

ID=20435846

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001248998A Abandoned AU2001248998A1 (en) 2000-04-07 2001-04-05 Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1- naphthalenemethanamine (terbinafine)

Country Status (7)

Country Link
AU (1) AU2001248998A1 (en)
EE (1) EE200200583A (en)
HU (1) HUP0302919A3 (en)
LT (1) LT5051B (en)
LV (1) LV12955B (en)
SK (1) SK5202000A3 (en)
WO (1) WO2001077064A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100459275B1 (en) * 2001-12-28 2004-12-03 주식회사유한양행 A PROCESS FOR THE PREPARATION OF TERBINAFINE OR HCl SALT THEREOF
KR20030066186A (en) * 2002-02-05 2003-08-09 한솔케미언스 주식회사 Process for preparation of Terbinafin
ITMI20022534A1 (en) 2002-11-29 2004-05-30 Dinamite Dipharma S P A PROCEDURE FOR THE PREPARATION OF TERBINAFINA BY USING PLATINUM AS A CATALYST.
CN101300242B (en) * 2005-10-31 2012-07-11 詹森药业有限公司 Processes for the preparation of cyclopropyl-amide derivatives
AU2006309077A1 (en) * 2005-10-31 2007-05-10 Janssen Pharmaceutica N.V. Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
CN101624328B (en) * 2009-07-31 2011-12-14 山东铂源化学有限公司 Method for synthesizing (E)-1-chlorine-6, 6-dimethyl-2-heptylene-4-alkyne
CN104725240B (en) * 2015-02-12 2017-05-24 吉林修正药业新药开发有限公司 Method for preparing terbinafine hydrochloride Z-shaped isomer
CN105016966A (en) * 2015-07-31 2015-11-04 江苏恒润制药有限公司 Preparation method of (E)-1-chloro-6,6-dimethyl-2-heptene-4-alkyne
CN111153807B (en) * 2020-01-16 2023-01-06 河南豫辰药业股份有限公司 Preparation method of N, N-dimethylamino chloropropane hydrochloride

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19375084I2 (en) 1979-08-22 2000-11-16 Novartis Ag Propenylamine Process for their preparation pharmaceutical compositions containing them and their use as medicines
CH678527A5 (en) 1989-06-22 1991-09-30 Sandoz Ag Trans(E)-N-(1-naphthyl:methyl)-heptenyl-amine prepn. - by simultaneously converting crude mixt. contg. cis and trans isomers to salt and precipitating trans isomer
JP3116364B2 (en) * 1989-10-02 2000-12-11 萬有製薬株式会社 Method for producing enyne derivatives
NZ280065A (en) 1995-09-20 1998-04-27 Apotex Inc Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives

Also Published As

Publication number Publication date
WO2001077064A1 (en) 2001-10-18
HUP0302919A3 (en) 2004-09-28
LT2002103A (en) 2003-05-26
EE200200583A (en) 2004-04-15
LV12955B (en) 2003-04-20
WO2001077064A8 (en) 2002-01-03
SK5202000A3 (en) 2001-12-03
HUP0302919A2 (en) 2003-12-29
LT5051B (en) 2003-08-25

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