EE05343B1 - Inhalable solution composition containing the tiotropium salt - Google Patents

Inhalable solution composition containing the tiotropium salt

Info

Publication number
EE05343B1
EE05343B1 EEP200300202A EEP200300202A EE05343B1 EE 05343 B1 EE05343 B1 EE 05343B1 EE P200300202 A EEP200300202 A EE P200300202A EE P200300202 A EEP200300202 A EE P200300202A EE 05343 B1 EE05343 B1 EE 05343B1
Authority
EE
Estonia
Prior art keywords
composition containing
solution composition
tiotropium salt
inhalable solution
inhalable
Prior art date
Application number
EEP200300202A
Other languages
Estonian (et)
Inventor
Drechsel Karin
Niklaus-Humke Barbara
Schmelzer Christel
Barth Petra
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7661727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE05343(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma Gmbh & Co. Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co. Kg
Publication of EE200300202A publication Critical patent/EE200300202A/en
Publication of EE05343B1 publication Critical patent/EE05343B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200300202A 2000-10-31 2001-10-24 Inhalable solution composition containing the tiotropium salt EE05343B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10054042 2000-10-31
PCT/EP2001/012296 WO2002036591A2 (en) 2000-10-31 2001-10-24 Inhalative solution formulation containing a tiotropium salt

Publications (2)

Publication Number Publication Date
EE200300202A EE200300202A (en) 2003-10-15
EE05343B1 true EE05343B1 (en) 2010-10-15

Family

ID=7661727

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300202A EE05343B1 (en) 2000-10-31 2001-10-24 Inhalable solution composition containing the tiotropium salt

Country Status (33)

Country Link
EP (1) EP1335729A2 (en)
JP (1) JP4559703B2 (en)
KR (1) KR100983208B1 (en)
CN (1) CN1237970C (en)
AR (1) AR038765A1 (en)
AU (2) AU2174102A (en)
BG (1) BG66425B1 (en)
BR (1) BR0115016A (en)
CA (1) CA2427583C (en)
CZ (1) CZ305033B6 (en)
DE (1) DE10152369A1 (en)
EA (1) EA009068B1 (en)
EC (1) ECSP034570A (en)
EE (1) EE05343B1 (en)
HK (1) HK1060569A1 (en)
HR (1) HRP20030337A2 (en)
HU (1) HUP0301377A3 (en)
IL (2) IL155676A0 (en)
ME (1) ME00242B (en)
MX (1) MXPA03003750A (en)
MY (1) MY132777A (en)
NO (1) NO332524B1 (en)
NZ (1) NZ526024A (en)
PE (1) PE20020518A1 (en)
PL (1) PL361001A1 (en)
SA (1) SA01220503B1 (en)
SK (1) SK288031B6 (en)
TW (1) TWI296934B (en)
UA (1) UA76435C2 (en)
UY (1) UY26991A1 (en)
WO (1) WO2002036591A2 (en)
YU (1) YU33103A (en)
ZA (1) ZA200303045B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070092334A (en) 2000-04-28 2007-09-12 코산 바이오사이언시즈, 인코포레이티드 Production of polyketides
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
CA2544733A1 (en) * 2003-10-09 2005-04-21 Inverseon, Inc. Methods for treating diseases and conditions with inverse agonists and for screening for agents acting as inverse agonists
SE0303269L (en) * 2003-12-03 2005-06-04 Microdrug Ag Medical product
MX2007011273A (en) * 2005-03-16 2007-11-08 Meda Pharma Gmbh & Co Kg The combination of anticholinergics and leukotriene recptor antagonists for the treatment of repiratory diseases.
AU2007267523B2 (en) * 2006-05-26 2012-02-09 Dey, L.P. Nebulizable compositions of quaternary ammonium muscarinic receptor antagonists
CN100446770C (en) * 2007-01-10 2008-12-31 上海现代药物制剂工程研究中心有限公司 Water aerosol containing beclomethasone dipropionate
TR200907237A2 (en) * 2009-09-23 2011-04-21 Bi̇lgi̇ç Mahmut Tiotropium dry powder combination
CN111936124A (en) * 2018-07-26 2020-11-13 四川海思科制药有限公司 Aerosol pharmaceutical composition containing glycopyrronium salt and indacaterol salt, and preparation method and application thereof
WO2020019953A1 (en) * 2018-07-26 2020-01-30 四川海思科制药有限公司 Aerosol pharmaceutical composition containing a glycopyrrolate salt, preparation method therefor, and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
DE4203306A1 (en) * 1992-02-06 1993-08-12 Ig Spruehtechnik Gmbh ASTHMA OR PULMONAL AEROSOL PREPARATIONS WITH LECITHIN
TW537903B (en) * 1995-06-27 2003-06-21 Boehringer Ingelheim Kg New stable pharmaceutical preparation for producing propellant gas-free aerosols
US5824669A (en) * 1996-03-22 1998-10-20 Nitromed, Inc. Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
EP0954318A1 (en) * 1996-06-04 1999-11-10 The Procter & Gamble Company A nasal spray containing an intranasal steroid and an antihistamine
DE19653969A1 (en) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg New aqueous pharmaceutical preparation for the production of propellant-free aerosols
JPH10298107A (en) * 1997-04-25 1998-11-10 Taisho Pharmaceut Co Ltd Pharmaceutical composition
NZ509489A (en) * 1998-08-04 2002-10-25 Jago Res A Medicinal aerosol formulations comprising cromoglycic acid and/or nedocromil
DE19847968A1 (en) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Separate storage of an active material and a solvent comprises a closure cap and a container, with a chamber attached to the unit.

Also Published As

Publication number Publication date
JP2004523482A (en) 2004-08-05
UY26991A1 (en) 2002-06-20
BR0115016A (en) 2005-05-03
KR100983208B1 (en) 2010-09-20
WO2002036591A3 (en) 2002-07-25
SA01220503B1 (en) 2007-03-10
BG107726A (en) 2004-11-30
JP4559703B2 (en) 2010-10-13
SK5262003A3 (en) 2003-10-07
IL155676A (en) 2012-05-31
NO332524B1 (en) 2012-10-08
CA2427583A1 (en) 2002-05-10
EE200300202A (en) 2003-10-15
ECSP034570A (en) 2003-06-25
AU2002221741B2 (en) 2007-04-05
PL361001A1 (en) 2004-09-20
CZ305033B6 (en) 2015-04-08
PE20020518A1 (en) 2002-07-12
HK1060569A1 (en) 2004-08-13
AU2174102A (en) 2002-05-15
NZ526024A (en) 2005-10-28
KR20040010552A (en) 2004-01-31
HUP0301377A2 (en) 2003-10-28
MY132777A (en) 2007-10-31
AR038765A1 (en) 2005-01-26
SK288031B6 (en) 2012-12-03
TWI296934B (en) 2008-05-21
NO20031914L (en) 2003-06-23
MXPA03003750A (en) 2004-10-15
MEP40708A (en) 2011-02-10
ME00242B (en) 2011-05-10
CN1237970C (en) 2006-01-25
BG66425B1 (en) 2014-04-30
UA76435C2 (en) 2006-08-15
EP1335729A2 (en) 2003-08-20
ZA200303045B (en) 2004-04-22
CA2427583C (en) 2008-02-12
IL155676A0 (en) 2003-11-23
HUP0301377A3 (en) 2005-12-28
YU33103A (en) 2006-05-25
EA200300483A1 (en) 2003-12-25
CN1473044A (en) 2004-02-04
NO20031914D0 (en) 2003-04-29
WO2002036591A2 (en) 2002-05-10
CZ20031487A3 (en) 2003-09-17
HRP20030337A2 (en) 2005-04-30
EA009068B1 (en) 2007-10-26
DE10152369A1 (en) 2002-05-08

Similar Documents

Publication Publication Date Title
DE60020343D1 (en) CILOSTAZOL CONTAINING PREPARATION
ATE275391T1 (en) NEW INHALATION POWDER CONTAINING TIOTROPIUM
DE60135560D1 (en) VALSARTAN SALT
NO20022922L (en) Inhalation
NO20042154L (en) Therapeutic isoquinoline compounds
NO20032909L (en) Glucopyranosyloxypyrazole derivatives as well as their drug use
EE200200656A (en) Tropane derivatives for therapeutic use
ATE313952T1 (en) STABLE BIOCIDAL COMPOSITION
EE05020B1 (en) The pharmaceutical composition of G1buride
HK1129111A1 (en) Tiotropium salts, pharmaceutical formulations containing the salts and the use thereof
DK1299095T3 (en) Clear aqueous anesthetic preparation
NO20022921D0 (en) Inhalation
ATE324883T1 (en) PHARMACEUTICAL COMPOSITION CONTAINING LUMIRACOXIB
EE200300202A (en) Inhalable solution composition containing the tiotropium salt
ATE350016T1 (en) PHARMACEUTICAL COMPOSITION CONTAINING BICALUTAMID
EE05314B1 (en) Inhalable solution composition containing the tiotropium salt
PT1227817E (en) AQUOSA PHARMACEUTICAL COMPOSITION CYCLOSONIDE CONTAINING
DE60122948D1 (en) Fungicidal compositions containing fludioxonil
ATE297187T1 (en) RESORCINO CONTAINING COMPOSITION
DE60124516D1 (en) COMBINATION OF THE LEZITHINE WITH ASCORBIC ACID
ATE350029T1 (en) PHARMACEUTICAL COMPOSITION CONTAINING GAMMA-BUTYROBETAIN
EE200300045A (en) Crystalline drug substance
IS6712A (en) Angular torsemide
SE0004749D0 (en) New salt form
SE9903847D0 (en) Nicotine composition

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20101231