ECSP17072984A - Procesos farmacéuticos novedosos - Google Patents
Procesos farmacéuticos novedososInfo
- Publication number
- ECSP17072984A ECSP17072984A ECIEPI201772984A ECPI201772984A ECSP17072984A EC SP17072984 A ECSP17072984 A EC SP17072984A EC IEPI201772984 A ECIEPI201772984 A EC IEPI201772984A EC PI201772984 A ECPI201772984 A EC PI201772984A EC SP17072984 A ECSP17072984 A EC SP17072984A
- Authority
- EC
- Ecuador
- Prior art keywords
- novel pharmaceutical
- cab
- pharmaceutical processes
- vonoprazan
- revaprazan
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La invención proporciona un bloqueador de ácido competitivo con potasio (P-CAB) para usarse en el tratamiento, prevención y/o reducción de síntomas de la enfermedad por reflujo gastroesofágico (ERGE) en pacientes que responden de manera parcial a un inhibidor de la bomba de protones (IBP). El P-CAB puede, por ejemplo, seleccionarse de 1-[5- (2-fluorofenil)- 1-(piridin- 3-ilsulfonil)- 1H-pirrol- 3-il]- N-metilmetanamina (vonoprazan), revaprazan (YH1855), YH4808, RQ-4 y CS-526, o una sal de los mismos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1505526.2A GB201505526D0 (en) | 2015-03-31 | 2015-03-31 | Novel pharmaceutical uses |
GBGB1521015.6A GB201521015D0 (en) | 2015-11-27 | 2015-11-27 | Novel pharmaceutical uses |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP17072984A true ECSP17072984A (es) | 2018-02-28 |
Family
ID=55806738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECIEPI201772984A ECSP17072984A (es) | 2015-03-31 | 2017-10-31 | Procesos farmacéuticos novedosos |
Country Status (22)
Country | Link |
---|---|
US (2) | US20180085361A1 (es) |
EP (1) | EP3277279A1 (es) |
JP (1) | JP2018513140A (es) |
KR (1) | KR20170132260A (es) |
CN (1) | CN107530335A (es) |
AU (1) | AU2016241069A1 (es) |
BR (1) | BR112017021024A2 (es) |
CA (1) | CA2981244A1 (es) |
CL (1) | CL2017002325A1 (es) |
CO (1) | CO2017010019A2 (es) |
CR (1) | CR20170404A (es) |
DO (1) | DOP2017000218A (es) |
EA (1) | EA201792148A1 (es) |
EC (1) | ECSP17072984A (es) |
IL (1) | IL254419A0 (es) |
MA (1) | MA41850A (es) |
MX (1) | MX2017012414A (es) |
PE (1) | PE20180195A1 (es) |
PH (1) | PH12017501751A1 (es) |
SG (1) | SG11201706739WA (es) |
TN (1) | TN2017000416A1 (es) |
WO (1) | WO2016159386A1 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11696893B2 (en) | 2017-07-10 | 2023-07-11 | Takeda Pharmaceutical Company Limited | Preparation comprising vonoprazan |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2980109A1 (en) | 2015-03-31 | 2016-10-06 | Mutabilis | Heterocyclic compounds and their use in preventing or treating bacterial infections |
WO2024027549A1 (zh) * | 2022-08-04 | 2024-02-08 | 江苏柯菲平医药股份有限公司 | 一种含有吡咯类胃酸分泌抑制剂的药物组合物及其制备方法 |
CN116270443A (zh) * | 2022-10-27 | 2023-06-23 | 广州白云山天心制药股份有限公司 | 富马酸伏诺拉生注射液及其制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7662832B2 (en) | 2004-09-03 | 2010-02-16 | Yuhan Corporation | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof |
US20080255200A1 (en) * | 2007-04-11 | 2008-10-16 | Auspex Pharmaceuticals, Inc. | Substituted benzimidazoles |
BRPI0916689A2 (pt) | 2008-07-28 | 2015-11-17 | Takeda Pharmaceutical | composição farmacêutica estabilizada, preparação sólida, e, métodos para estabilizar uma composição farmacêutica, e para estabilizar uma preparação sólida. |
WO2011004882A1 (ja) | 2009-07-09 | 2011-01-13 | ラクオリア創薬株式会社 | 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤 |
CA2902624C (en) | 2013-02-28 | 2021-05-18 | Takeda Pharmaceutical Company Limited | Method for producing sulfonyl chloride compound |
CN103951652B (zh) * | 2014-04-18 | 2015-09-23 | 潍坊博创国际生物医药研究院 | 5-(2-氟苯基)-n-甲基-1-(3-吡啶基磺酰基)-1h-吡咯-3-甲胺水溶性有机酸盐和注射剂及它们的制备方法 |
-
2016
- 2016-03-29 MA MA041850A patent/MA41850A/fr unknown
- 2016-03-30 US US15/563,417 patent/US20180085361A1/en not_active Abandoned
- 2016-03-30 KR KR1020177031036A patent/KR20170132260A/ko unknown
- 2016-03-30 CR CR20170404A patent/CR20170404A/es unknown
- 2016-03-30 TN TNP/2017/000416A patent/TN2017000416A1/en unknown
- 2016-03-30 EP EP16718032.2A patent/EP3277279A1/en not_active Withdrawn
- 2016-03-30 EA EA201792148A patent/EA201792148A1/ru unknown
- 2016-03-30 WO PCT/JP2016/061185 patent/WO2016159386A1/en active Application Filing
- 2016-03-30 JP JP2017550959A patent/JP2018513140A/ja active Pending
- 2016-03-30 AU AU2016241069A patent/AU2016241069A1/en not_active Abandoned
- 2016-03-30 BR BR112017021024A patent/BR112017021024A2/pt not_active Application Discontinuation
- 2016-03-30 MX MX2017012414A patent/MX2017012414A/es unknown
- 2016-03-30 PE PE2017001509A patent/PE20180195A1/es unknown
- 2016-03-30 SG SG11201706739WA patent/SG11201706739WA/en unknown
- 2016-03-30 CN CN201680020346.5A patent/CN107530335A/zh active Pending
- 2016-03-30 CA CA2981244A patent/CA2981244A1/en not_active Abandoned
-
2017
- 2017-09-11 IL IL254419A patent/IL254419A0/en unknown
- 2017-09-14 CL CL2017002325A patent/CL2017002325A1/es unknown
- 2017-09-20 DO DO2017000218A patent/DOP2017000218A/es unknown
- 2017-09-25 PH PH12017501751A patent/PH12017501751A1/en unknown
- 2017-10-03 CO CONC2017/0010019A patent/CO2017010019A2/es unknown
- 2017-10-31 EC ECIEPI201772984A patent/ECSP17072984A/es unknown
-
2018
- 2018-11-01 US US16/178,335 patent/US20190070159A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11696893B2 (en) | 2017-07-10 | 2023-07-11 | Takeda Pharmaceutical Company Limited | Preparation comprising vonoprazan |
Also Published As
Publication number | Publication date |
---|---|
CA2981244A1 (en) | 2016-10-06 |
PH12017501751A1 (en) | 2018-04-11 |
CR20170404A (es) | 2018-01-10 |
CN107530335A (zh) | 2018-01-02 |
TN2017000416A1 (en) | 2019-01-16 |
EP3277279A1 (en) | 2018-02-07 |
MX2017012414A (es) | 2018-01-26 |
PE20180195A1 (es) | 2018-01-26 |
WO2016159386A1 (en) | 2016-10-06 |
CO2017010019A2 (es) | 2018-02-20 |
US20180085361A1 (en) | 2018-03-29 |
US20190070159A1 (en) | 2019-03-07 |
BR112017021024A2 (pt) | 2018-07-03 |
DOP2017000218A (es) | 2018-01-31 |
MA41850A (fr) | 2018-02-06 |
SG11201706739WA (en) | 2017-09-28 |
CL2017002325A1 (es) | 2017-12-29 |
IL254419A0 (en) | 2017-11-30 |
EA201792148A1 (ru) | 2018-02-28 |
AU2016241069A1 (en) | 2017-09-21 |
JP2018513140A (ja) | 2018-05-24 |
KR20170132260A (ko) | 2017-12-01 |
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