ECSP099828A - Uso de ranolazina para peptido natriuretico tipo-cerebral elevado - Google Patents
Uso de ranolazina para peptido natriuretico tipo-cerebral elevadoInfo
- Publication number
- ECSP099828A ECSP099828A EC2009009828A ECSP099828A ECSP099828A EC SP099828 A ECSP099828 A EC SP099828A EC 2009009828 A EC2009009828 A EC 2009009828A EC SP099828 A ECSP099828 A EC SP099828A EC SP099828 A ECSP099828 A EC SP099828A
- Authority
- EC
- Ecuador
- Prior art keywords
- ranolazine
- cerebral
- natural peptide
- elevated type
- coronary
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Vascular Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Esta invención se encuentra orientada al uso de ranolazina para reducir el riesgo de accidentes adversos coronarios en un paciente mamífero. Típicamente, los péptidos natriuréticos se encuentran asociados con la enfermedad coronaria, sindrome coronario agudo, y/o disfunción diastólica. La ranolazina puede ser administrada a un paciente como una solución intravenosa o en una forma posológica oral.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94121007P | 2007-05-31 | 2007-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP099828A true ECSP099828A (es) | 2010-01-29 |
Family
ID=39929825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2009009828A ECSP099828A (es) | 2007-05-31 | 2009-12-28 | Uso de ranolazina para peptido natriuretico tipo-cerebral elevado |
Country Status (12)
Country | Link |
---|---|
US (1) | US20080299195A1 (es) |
EP (1) | EP2170333B1 (es) |
KR (1) | KR20100033490A (es) |
CN (1) | CN101896181A (es) |
CA (1) | CA2689633A1 (es) |
EA (1) | EA200971073A1 (es) |
EC (1) | ECSP099828A (es) |
ES (1) | ES2402675T3 (es) |
HK (1) | HK1143066A1 (es) |
IL (1) | IL202493A0 (es) |
WO (1) | WO2008150565A2 (es) |
ZA (1) | ZA200908657B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8822473B2 (en) * | 2002-05-21 | 2014-09-02 | Gilead Sciences, Inc. | Method of treating diabetes |
CA2486712C (en) * | 2002-05-21 | 2012-01-03 | Cv Therapeutics, Inc. | Method of treating diabetes |
CA2677931A1 (en) * | 2007-02-13 | 2008-08-21 | Cv Therapeutics, Inc. | Use of ranolazine for the treatment of cardiovascular diseases |
US20090111826A1 (en) * | 2007-02-13 | 2009-04-30 | Louis Lange | Use of ranolazine for the treatment of cardiovascular diseases |
CA2678319A1 (en) * | 2007-02-13 | 2008-08-21 | Cv Therapeutics, Inc. | Use of ranolazine for the treatment of coronary microvascular diseases |
JP2010518171A (ja) * | 2007-02-13 | 2010-05-27 | ギリアード・パロ・アルト・インコーポレイテッド | 非冠微小血管疾患の処置のためのラノラジンの使用 |
US20080233191A1 (en) * | 2007-03-22 | 2008-09-25 | Brent Blackburn | Use of ranolazine for elevated brain-type natriuretic peptide |
US20090012103A1 (en) * | 2007-07-05 | 2009-01-08 | Matthew Abelman | Substituted heterocyclic compounds |
MX2011012140A (es) * | 2009-05-14 | 2012-02-28 | Gilead Sciences Inc | Ranolazina para el tratamiento de problemas del snc. |
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US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
EP0714660B1 (en) * | 1989-06-23 | 2002-09-04 | Syntex (U.S.A.) LLC | Ranolazine and related piperazines for protecting skeletal muscles |
US5455045A (en) * | 1993-05-13 | 1995-10-03 | Syntex (U.S.A.) Inc. | High dose formulations |
US20030077229A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs |
US6541479B1 (en) * | 1997-12-02 | 2003-04-01 | Massachusetts College Of Pharmacy | Calcium channel blockers |
US6897305B2 (en) * | 1998-06-08 | 2005-05-24 | Theravance, Inc. | Calcium channel drugs and uses |
US6479496B1 (en) * | 1998-09-10 | 2002-11-12 | Cv Therapeutics, Inc. | Methods for treating angina with ranolazine |
US6303607B1 (en) * | 1998-09-10 | 2001-10-16 | Cv Therapeutics, Inc. | Method for administering a sustained release ranolanolazine formulation |
US6734192B1 (en) * | 1999-08-23 | 2004-05-11 | Mp-1 Inc. | Treatment of viral infections |
US20050245502A1 (en) * | 1999-08-23 | 2005-11-03 | Phoenix Biosciences | Treatments for viral infections |
US6803457B1 (en) * | 1999-09-30 | 2004-10-12 | Pfizer, Inc. | Compounds for the treatment of ischemia |
US6528511B2 (en) * | 2000-02-18 | 2003-03-04 | Cv Therapeutics, Inc. | Partial fatty acid oxidation inhibitors in the treatment of congestive heart failure |
US20030220312A1 (en) * | 2000-05-11 | 2003-11-27 | G.D. Searle & Co. | Epoxy-steroidal aldosterone antagonist and calcium channel blocker combination therapy for treatment of cardiovascular disorders |
US20020052377A1 (en) * | 2000-07-21 | 2002-05-02 | Wolff Andrew A. | Method for treating angina |
AU2001278045B2 (en) * | 2000-07-27 | 2006-08-03 | Pharmacia Corporation | Epoxy-steroidal aldosterone antagonist and calcium channel blocker combination therapy for treatment of congestive heart failure |
GB0028414D0 (en) * | 2000-11-22 | 2001-01-03 | Univ Leeds | Flush preservation solution |
US6423705B1 (en) * | 2001-01-25 | 2002-07-23 | Pfizer Inc. | Combination therapy |
BR0206644A (pt) * | 2001-01-26 | 2004-02-25 | Schering Corp | Combinações de inibidor(es) de absorção de esteróis com agente(s) cardiovascular(es) para o tratamento de condições vasculares |
DE10126328A1 (de) * | 2001-05-30 | 2002-12-12 | Infineon Technologies Ag | Integrierte, abstimmbare Kapazität |
US20030220310A1 (en) * | 2001-07-27 | 2003-11-27 | Schuh Joseph R. | Epoxy-steroidal aldosterone antagonist and calcium channel blocker combination therapy for treatment of congestive heart failure |
US20050250676A1 (en) * | 2001-11-19 | 2005-11-10 | Aventis Pharma Deutschland Gmbh | Method of activating insulin receptor substrate-2 to stimulate insulin production |
WO2003066035A2 (en) * | 2002-02-08 | 2003-08-14 | Smithkline Beecham Corporation | Compounds for inhibiting insulin secretion and methods related thereto |
RU2308976C2 (ru) * | 2002-02-15 | 2007-10-27 | Си Ви Терапьютикс, Инк. | Полимерное покрытие для медицинских устройств |
US20030220344A1 (en) * | 2002-04-04 | 2003-11-27 | Luiz Belardinelli | Method of treating arrhythmias |
CA2486712C (en) * | 2002-05-21 | 2012-01-03 | Cv Therapeutics, Inc. | Method of treating diabetes |
US8822473B2 (en) * | 2002-05-21 | 2014-09-02 | Gilead Sciences, Inc. | Method of treating diabetes |
WO2004079372A1 (en) * | 2003-03-05 | 2004-09-16 | Metabolex Inc. | Methods and compositions for treating and diagnosing diabetes and related diseases involving beta-trp |
EP2377528B1 (en) * | 2003-06-12 | 2014-02-19 | The Board of Regents of the University of Colorado | Fatty acid metabolism inhibitors for use in the treatment of cancer |
WO2005002597A1 (en) * | 2003-07-02 | 2005-01-13 | Polycord, Inc. | Method for delivering polymerized therapeutic agent compositions and compositions thereof |
US7060723B2 (en) * | 2003-08-29 | 2006-06-13 | Allergan, Inc. | Treating neurological disorders using selective antagonists of persistent sodium current |
ES2258365B1 (es) * | 2003-10-03 | 2007-12-01 | Lacer, S.A. | Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos. |
WO2005070126A2 (en) * | 2004-01-08 | 2005-08-04 | The Regents Of The University Of Colorado | Methods and compositions for treating human diseases and wounds with ucp and fas inhibitors |
US8829051B2 (en) * | 2004-05-24 | 2014-09-09 | Geoffrey C. GURTNER | Method of treating or preventing pathologic effects of acute increases in hyperglycemia and/or acute increases of free fatty acid flux |
SG156681A1 (en) * | 2004-11-09 | 2009-11-26 | Cv Therapeutics Inc | Use of ranolazine in combination with at least one remodeling agent for reversing left ventricular remodeling in the treatment of heart failure |
KR20070093988A (ko) * | 2005-01-06 | 2007-09-19 | 씨브이 쎄러퓨틱스, 인코포레이티드 | 라놀라진 함유 서방성 약제학적 제형물 |
US20060205727A1 (en) * | 2005-03-11 | 2006-09-14 | Wayne Kaesemeyer | Combination therapy for endothelial dysfunction, angina and diabetes |
WO2008080012A1 (en) * | 2006-12-21 | 2008-07-03 | Cv Therapeutics, Inc. | Reduction of cardiovascular symptoms |
CA2678319A1 (en) * | 2007-02-13 | 2008-08-21 | Cv Therapeutics, Inc. | Use of ranolazine for the treatment of coronary microvascular diseases |
JP2010518171A (ja) * | 2007-02-13 | 2010-05-27 | ギリアード・パロ・アルト・インコーポレイテッド | 非冠微小血管疾患の処置のためのラノラジンの使用 |
CA2677931A1 (en) * | 2007-02-13 | 2008-08-21 | Cv Therapeutics, Inc. | Use of ranolazine for the treatment of cardiovascular diseases |
US20090111826A1 (en) * | 2007-02-13 | 2009-04-30 | Louis Lange | Use of ranolazine for the treatment of cardiovascular diseases |
US20080233191A1 (en) * | 2007-03-22 | 2008-09-25 | Brent Blackburn | Use of ranolazine for elevated brain-type natriuretic peptide |
US20100130436A1 (en) * | 2008-11-25 | 2010-05-27 | Gilead Palo Alto, Inc. | Co-administration of ranolazine and cardiac glycosides |
MX2011012140A (es) * | 2009-05-14 | 2012-02-28 | Gilead Sciences Inc | Ranolazina para el tratamiento de problemas del snc. |
-
2008
- 2008-03-24 EA EA200971073A patent/EA200971073A1/ru unknown
- 2008-03-24 WO PCT/US2008/058063 patent/WO2008150565A2/en active Application Filing
- 2008-03-24 ES ES08732776T patent/ES2402675T3/es active Active
- 2008-03-24 EP EP08732776A patent/EP2170333B1/en active Active
- 2008-03-24 KR KR1020097027109A patent/KR20100033490A/ko not_active Application Discontinuation
- 2008-03-24 US US12/054,334 patent/US20080299195A1/en not_active Abandoned
- 2008-03-24 CA CA002689633A patent/CA2689633A1/en not_active Abandoned
- 2008-03-24 CN CN2008801009580A patent/CN101896181A/zh active Pending
-
2009
- 2009-12-03 IL IL202493A patent/IL202493A0/en unknown
- 2009-12-07 ZA ZA200908657A patent/ZA200908657B/xx unknown
- 2009-12-28 EC EC2009009828A patent/ECSP099828A/es unknown
-
2010
- 2010-10-06 HK HK10109528.0A patent/HK1143066A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP2170333A2 (en) | 2010-04-07 |
WO2008150565A2 (en) | 2008-12-11 |
ZA200908657B (en) | 2010-08-25 |
EA200971073A1 (ru) | 2010-08-30 |
CN101896181A (zh) | 2010-11-24 |
US20080299195A1 (en) | 2008-12-04 |
KR20100033490A (ko) | 2010-03-30 |
ES2402675T8 (es) | 2013-06-25 |
EP2170333B1 (en) | 2013-02-20 |
AU2008260480A1 (en) | 2008-12-11 |
ES2402675T3 (es) | 2013-05-07 |
WO2008150565A3 (en) | 2009-04-02 |
HK1143066A1 (en) | 2010-12-24 |
CA2689633A1 (en) | 2008-12-11 |
IL202493A0 (en) | 2011-07-31 |
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