ECSP044862A - Pirenzepine ophthalmic gel - Google Patents
Pirenzepine ophthalmic gelInfo
- Publication number
- ECSP044862A ECSP044862A EC2004004862A ECSP044862A ECSP044862A EC SP044862 A ECSP044862 A EC SP044862A EC 2004004862 A EC2004004862 A EC 2004004862A EC SP044862 A ECSP044862 A EC SP044862A EC SP044862 A ECSP044862 A EC SP044862A
- Authority
- EC
- Ecuador
- Prior art keywords
- ophthalmic gel
- pirenzepine
- pirenzepine ophthalmic
- gel
- pyrenzepine
- Prior art date
Links
- 229940100655 ophthalmic gel Drugs 0.000 title 1
- RMHMFHUVIITRHF-UHFFFAOYSA-N pirenzepine Chemical compound C1CN(C)CCN1CC(=O)N1C2=NC=CC=C2NC(=O)C2=CC=CC=C21 RMHMFHUVIITRHF-UHFFFAOYSA-N 0.000 title 1
- 229960004633 pirenzepine Drugs 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000001491 myopia Diseases 0.000 abstract 1
- 230000004379 myopia Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Es un objeto primario de la presente invención proporcionar una formulación oftálmica acuosa, para tratar la miopía, ésta formulación comprende la pirenzepina en combinación con un portador de gel, aceptable farmacéuticamente
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29373101P | 2001-05-25 | 2001-05-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP044862A true ECSP044862A (es) | 2004-03-23 |
Family
ID=23130330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2004004862A ECSP044862A (es) | 2001-05-25 | 2004-01-23 | Pirenzepine ophthalmic gel |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20040137069A1 (es) |
| EP (1) | EP1397132A4 (es) |
| JP (1) | JP2004531569A (es) |
| KR (1) | KR20040018380A (es) |
| CN (1) | CN1509172A (es) |
| BR (1) | BR0210013A (es) |
| CA (1) | CA2447562A1 (es) |
| EC (1) | ECSP044862A (es) |
| HU (1) | HUP0304071A2 (es) |
| IL (1) | IL158904A0 (es) |
| MX (1) | MXPA03010655A (es) |
| NO (1) | NO20035224D0 (es) |
| NZ (1) | NZ529615A (es) |
| PL (1) | PL366924A1 (es) |
| RU (1) | RU2297831C2 (es) |
| WO (1) | WO2002096418A1 (es) |
| ZA (1) | ZA200309791B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070033032A (ko) * | 2004-07-16 | 2007-03-23 | 프로테오시스 악티엔게젤샤프트 | 세포보호제로서 parp 및 sir 조절 활성을 갖는무스카린 길항제 |
| JP4963359B2 (ja) * | 2005-01-12 | 2012-06-27 | ロート製薬株式会社 | 眼局所適用製剤 |
| NZ572193A (en) | 2006-03-31 | 2011-10-28 | Quadra Logic Tech Inc | Nasolacrimal drainage system implants for drug therapy with non-fluid swellable retention structure around drug core |
| RU2009128703A (ru) * | 2006-12-26 | 2011-02-10 | Клт Плаг Диливери, Инк. (Us) | Имплантаты, доставляющие лекарства, для уменьшения оптических дефектов |
| US10265265B2 (en) | 2007-03-15 | 2019-04-23 | Drug Delivery Solutions Limited | Topical composition |
| EP2008651A1 (en) | 2007-06-26 | 2008-12-31 | Drug Delivery Solutions Limited | A bioerodible patch |
| ES2538838T3 (es) | 2007-09-07 | 2015-06-24 | Mati Therapeutics Inc. | Método para preparar insertos de fármacos para liberación sostenida de agentes terapéuticos |
| WO2010083129A2 (en) | 2009-01-13 | 2010-07-22 | The Regents Of The University Of California | Implantable delivery vehicle for ocular delivery of muscarinic antagonists |
| HUE070784T2 (hu) * | 2010-10-25 | 2025-06-28 | Univ Manitoba | Terápiás készítmények diabéteszes szimmetrikus polineuropátia kezelésére |
| CN103533962B (zh) | 2011-03-14 | 2018-05-18 | 药品配送方案有限公司 | 一种眼用组合物 |
| RU2635185C2 (ru) * | 2013-12-17 | 2017-11-09 | Иван Дмитриевич Захаров | Фармацевтический препарат для профилактики и лечения прогрессирующей близорукости |
| WO2016172712A2 (en) | 2015-04-23 | 2016-10-27 | Sydnexis, Inc. | Ophthalmic composition |
| US9421199B2 (en) | 2014-06-24 | 2016-08-23 | Sydnexis, Inc. | Ophthalmic composition |
| EP3302426A4 (en) | 2015-05-29 | 2018-12-05 | Sydnexis, Inc. | D2o stabilized pharmaceutical formulations |
| CN105663137A (zh) * | 2016-01-14 | 2016-06-15 | 王真 | 哌仑西平在制备治疗脓毒症疾病的药物中的应用 |
| EA201892703A1 (ru) * | 2016-05-25 | 2019-04-30 | Сингапур Хелт Сервисиз Пте Лтд | Водная композиция, содержащая атропин |
| TWI852865B (zh) | 2017-11-03 | 2024-08-11 | 瑞士商愛爾康公司 | 氮雜雙環和二氮呯衍生物 |
| WO2019136358A1 (en) | 2018-01-05 | 2019-07-11 | Iveena Delivery Systems, Inc. | Treatment of myopic progression |
| EP3542788A1 (en) | 2018-03-19 | 2019-09-25 | MC2 Therapeutics Limited | Topical composition comprising calcipotriol and betamethasone dipropionate |
| MX2021011607A (es) * | 2019-03-26 | 2021-12-10 | Winsantor Inc | Formulaciones topicas para el tratamiento de neuropatias perifericas. |
| WO2020251926A1 (en) * | 2019-06-10 | 2020-12-17 | Jenivision Inc. | Methods and formulations for treating vision disorders |
| CA3146848A1 (en) * | 2019-07-11 | 2021-01-14 | University Of Utah Research Foundation | Multi-agent ocular formulations and treatment methods |
| KR102808906B1 (ko) * | 2021-06-18 | 2025-05-19 | 대우제약 주식회사 | 고점도 점안제를 무균여과하는 방법 |
| CN117338787A (zh) * | 2023-11-24 | 2024-01-05 | 南京恒道医药科技股份有限公司 | 一种眼用药物组合物及其制备方法 |
| WO2025171327A1 (en) * | 2024-02-09 | 2025-08-14 | Levation Pharma Ltd. | Methods for producing dermatological gel compositions |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU188852B (en) * | 1983-03-16 | 1986-05-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer |
| US4865599A (en) * | 1986-08-18 | 1989-09-12 | Houston Biotechnology, Inc. | Ophthalmic compositions for treating nerve degeneration |
| CA1336490C (en) * | 1988-06-03 | 1995-08-01 | Paul Michael Iuvone | Pharmacological treatment of ocular development |
| US5122522A (en) * | 1989-06-21 | 1992-06-16 | The Trustees Of The University Of Pennsylvania | Treatment and control of ocular development |
| US5360801A (en) * | 1989-06-21 | 1994-11-01 | The Trustees Of The University Of Pennsylvania | Pharmacological stimulation of eye growth |
| DE69033775T2 (de) * | 1989-06-21 | 2001-11-15 | Trustees Of The University Of Pennsylvania, Philadelphia | Verwendung eines Muskarinantagonists zur Herstellung eines Medikaments für die Behandlung und Regulierung der Augenentwicklung |
| US5055302A (en) * | 1990-02-22 | 1991-10-08 | Trustees Of The University Of Pennsylvania | Neuropeptide control of ocular growth |
| SU1827797A3 (ru) * | 1991-04-30 | 1996-05-20 | Н.Б. Леонидов | Лекарственный препарат для анестезии глаз |
| US5461808A (en) * | 1993-02-08 | 1995-10-31 | Fritts; Robert W. | Table top backlit display |
| US5461052A (en) * | 1993-04-30 | 1995-10-24 | The Trustees Of The University Of Pennsylvania | Prevention of myopia by tricyclic compounds |
| US5385939A (en) * | 1993-04-30 | 1995-01-31 | The Trustees Of The University Of Pennsylvania | GABA-ergic modulation of eye growth |
| US5516808A (en) * | 1994-10-27 | 1996-05-14 | Sawaya; Assad S. | Topical cellulose pharmaceutical formulation |
| US5888493A (en) * | 1996-12-05 | 1999-03-30 | Sawaya; Assad S. | Ophthalmic aqueous gel formulation and related methods |
| RU2135129C1 (ru) * | 1998-11-18 | 1999-08-27 | Ларионов Евгений Викторович | Глазные капли "корнеалон-плюс" |
| US6164282A (en) * | 1999-01-27 | 2000-12-26 | Allergan Sales, Inc. | Methods for restoring and/or enhancing accommodation in pseudo phakia |
-
2002
- 2002-05-01 KR KR10-2003-7015393A patent/KR20040018380A/ko not_active Ceased
- 2002-05-01 CA CA002447562A patent/CA2447562A1/en not_active Abandoned
- 2002-05-01 BR BR0210013-4A patent/BR0210013A/pt not_active IP Right Cessation
- 2002-05-01 EP EP02734130A patent/EP1397132A4/en not_active Withdrawn
- 2002-05-01 WO PCT/US2002/013823 patent/WO2002096418A1/en not_active Ceased
- 2002-05-01 CN CNA02810174XA patent/CN1509172A/zh active Pending
- 2002-05-01 NZ NZ529615A patent/NZ529615A/en unknown
- 2002-05-01 RU RU2003136735/15A patent/RU2297831C2/ru not_active IP Right Cessation
- 2002-05-01 JP JP2002592928A patent/JP2004531569A/ja not_active Withdrawn
- 2002-05-01 HU HU0304071A patent/HUP0304071A2/hu unknown
- 2002-05-01 PL PL02366924A patent/PL366924A1/xx not_active Application Discontinuation
- 2002-05-01 IL IL15890402A patent/IL158904A0/xx unknown
- 2002-05-01 MX MXPA03010655A patent/MXPA03010655A/es not_active Application Discontinuation
-
2003
- 2003-10-31 US US10/698,320 patent/US20040137069A1/en not_active Abandoned
- 2003-11-24 NO NO20035224A patent/NO20035224D0/no not_active Application Discontinuation
- 2003-12-18 ZA ZA200309791A patent/ZA200309791B/xx unknown
-
2004
- 2004-01-23 EC EC2004004862A patent/ECSP044862A/es unknown
-
2006
- 2006-04-07 US US11/400,635 patent/US20060188576A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1397132A4 (en) | 2006-12-13 |
| BR0210013A (pt) | 2004-08-10 |
| MXPA03010655A (es) | 2007-06-22 |
| CN1509172A (zh) | 2004-06-30 |
| WO2002096418A1 (en) | 2002-12-05 |
| RU2003136735A (ru) | 2005-03-27 |
| IL158904A0 (en) | 2004-05-12 |
| ZA200309791B (en) | 2004-10-04 |
| NZ529615A (en) | 2005-07-29 |
| US20060188576A1 (en) | 2006-08-24 |
| PL366924A1 (en) | 2005-02-07 |
| KR20040018380A (ko) | 2004-03-03 |
| EP1397132A1 (en) | 2004-03-17 |
| US20040137069A1 (en) | 2004-07-15 |
| RU2297831C2 (ru) | 2007-04-27 |
| CA2447562A1 (en) | 2002-12-05 |
| HUP0304071A2 (hu) | 2004-04-28 |
| JP2004531569A (ja) | 2004-10-14 |
| NO20035224D0 (no) | 2003-11-24 |
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